LOCUS       XM_005164094           10036 bp    mRNA    linear   VRT 12-MAY-2025
DEFINITION  PREDICTED: Danio rerio trinucleotide repeat containing adaptor 6C1
            (tnrc6c1), transcript variant X4, mRNA.
ACCESSION   XM_005164094
VERSION     XM_005164094.6
DBLINK      BioProject: PRJNA1248012
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_133178) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On May 12, 2025 this sequence version replaced XM_005164094.5.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_049306965.1-RS_2025_04
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 04/11/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10036
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /isolation_source="Zebrafish international resource
                     center"
                     /db_xref="taxon:7955"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="Fibroblasts and whole tissue"
                     /dev_stage="adult"
                     /ecotype="United States"
                     /geo_loc_name="USA"
                     /collection_date="2022-07-19"
                     /collected_by="National Human Genome Research Institute"
                     /genotype="Double heterozygous"
     gene            1..10036
                     /gene="tnrc6c1"
                     /note="trinucleotide repeat containing adaptor 6C1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 6 ESTs, 4278 long SRA reads, 15 Proteins"
                     /db_xref="GeneID:560874"
                     /db_xref="ZFIN:ZDB-GENE-030131-7440"
     misc_feature    1
                     /gene="tnrc6c1"
                     /experiment="COORDINATES: cap analysis [ECO:0007248]"
                     /note="transcription start site"
     CDS             645..6098
                     /gene="tnrc6c1"
                     /codon_start=1
                     /product="trinucleotide repeat-containing gene 6C protein
                     isoform X4"
                     /protein_id="XP_005164151.1"
                     /db_xref="GeneID:560874"
                     /db_xref="ZFIN:ZDB-GENE-030131-7440"
                     /translation="

MEEKKKKKQEEKKKKEAAQKKAAEQKTKVPDSAKPSPTPPLPNNPSIATNPPVPSASSSTGGNGKRAPSGNNQQQQQPPAAPRYPPREVPPRFRQHEHKQLLKRGQPLPIGSTALVQPASASTTPQPFSCQTNPELPPQSGLTAHYENIPPSRSATTASTNSCSSWDPLIIDERDTEAWPSISCKESHVPAGCPLDTESISDISSMSMATGAGQQGHFSANHTSKANVSHSGGLLSSQGGASRGWGSGQSPASGEGKNEVSSTSVGARGWGSSNFNLNLNPNANPSAWPVLGHEGSGMGGGSSGGSNPPPNLCSPPGTLPSQGSSNSGSIGGPNGNSASNGGSGNGSTTWGSIMPSDSSEPHSTPSTNVSFSSEPQNLNTDGPNHTKQEPRSPGHSLSNWGVGPPGMGSFVQSQGGSSQVNGDREPIWGNGDAKSGGGSKDSDWDSGHWVQGGASGTSGWGQAASSGDWGKHSNIDTKGWNSSGSPTQEQQLNSWVRGPNAPASEGSSDSMECHHRRRDRSSRDETSPILPAQDMDPRVLCNTGWGQTPVRQHTAWETEEAARSNRKNDIGTEAWGSSSNAANVGPTSNSGSANPNSGTTSRPDSGGKSEGPCPSTGAAPGWGTAMSSPQAGSGWADTTSNKKPSIGPGDWGSTSAGGPGGNLQKSGQTWGSEEKSPTWEDSHAKAKPQCWVEGPKSHGWGNGPGGESGSGGEWGEPGDGKKNGPSSSTWEGEGTGLNEGSRGWTKPSAGVGGNWGEAQRPSVPPQGWNNKPQEGTNGNSTSGSMGSWGGPSSVKQSCSGWNGGNGGGVKPDHTGDPTGWEEPSPPSIRRKMEIDDGTSVWGDPSTYNKTVNLWDRNNPGMQGKPGPSNANNVPNNHHHHPHHNQPPIQSHNHGGPNSNNNHISPDNAGPHQTGPSHNRTTHMNPGWGEMTNAHSKPEPLWGEPAAPAASVDNGTSAWGKPPGSCGSWGENGPEVYSRGNGPPGSAPCKPAPKSMQDSWGGGEDMGLSAGQWEQDEGDMWNNTASQESNSSCSSWGNPPKKGPPKGKVTNKQDETWIMNRLIKQLTDMGFPRDPAEEALKSNNMNLDQAMSALLEKKTELDKRGMGMSDYNNGLVNKPMGCRPSVISKESSSDRPPFLDKDAGLADDAQTSPFMPSPSLKLPMGSAALPGQSLGVAMQNLNNRQMQSGVFGSSGAAQARALQQQPPPQPSVPPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTLLNQLYQLQLAYQRLQIQQQMLQAQRSVSGPIRQQEQQVARTINNMQQQIQQHQRQLAQALLMKQQQQQPPPSHPGLHPNAGKSALDTFPSHPQASSLSVSDLQTKEPQSSPNSFSPYPISGLNPNMNVNCMEVGGLSIKDSPQPQSRLSQWTHPNSMDNLSGNSSPMEPNFNKHGAISAGPSLGPPSKPPLDDSYSPYNLISSSDSPASPLAPHDSWGQGKNANDKISNGTNVNWPPEFCPGVPWKGLQNIDPETDPNVTPGSVPSGPTINTNIQDVNRYLLRDRSGGKLSDMKSTWSPGPISHTQASLSHELWKVPQGPRNTTAPTRPPPGLTNTKPSSTWGGNTLGLVASWGGSYSSGTTWSTDSSSRSTSWLVLRNLTPQIDGSTLRTLCMQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFFAQGQSLTPTTSWQANPGTNQTRLGGGGTAATHPIGHWNSSSLGGGGAGTGSGGKASNELLWGGVPQYSSLWGPPSAEDGRVVGSPTPINTLLPGDLLSGESM"

     misc_feature    3498..3812
                     /gene="tnrc6c1"
                     /note="Argonaute hook; Region: Ago_hook; pfam10427"
                     /db_xref="CDD:463088"
     misc_feature    3819..3932
                     /gene="tnrc6c1"
                     /note="UBA domain found in trinucleotide repeat-containing
                     gene 6C protein (TNRC6C) and similar proteins; Region:
                     UBA_TNR6C; cd14283"
                     /db_xref="CDD:270469"
     misc_feature    4062..4727
                     /gene="tnrc6c1"
                     /note="M domain of GW182; Region: M_domain; pfam12938"
                     /db_xref="CDD:432890"
     misc_feature    4761..5501
                     /gene="tnrc6c1"
                     /note="TNRC6-PABC binding domain; Region: TNRC6-PABC_bdg;
                     pfam16608"
                     /db_xref="CDD:465195"
     misc_feature    5553..5795
                     /gene="tnrc6c1"
                     /note="RNA recognition motif (RRM) superfamily; Region:
                     RRM_SF; cl17169"
                     /db_xref="CDD:473069"
     polyA_site      10036
                     /gene="tnrc6c1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

agtttcaacaaaatggctgctggagcgccacaaacgaaatcccagtgaacgcttcacgtcagtgcagaatcgtttcaaatggatgcattggaatttccgagcattgggacattaattcgtgtggactcgtttgcatacgtgttatcgagctgaaaggcatgctgaaagatttccctttacgcactttatatacatccaaaagcatactaaagctcaaactgccagtgcgcgcgcgtctgtgagggtgcgcgcgtgaagctgcttcttaaaatcgccgaaatgttacacttgatcaaccttaagcttgctcgctgacgtgcagaattgtcgtttaatgtccttttcactgtttgcactggtatttgtttttagagattgtttctttcccccctctggataaattccactgcataataagaggtgaattcctcaactggaaagtcaggctcgccattgcagttcactgcaagagcgagagagtctgactgcgactgaatatatctgatctgtgtcagtacgggtatcgacaacatcctccttcaccatgcagcttatgcaccccatctgaaccgcaaactgcagttgctccgtgtgcgaaataaagcctcgggacaaaacacatcacacaagaggagaaccatttgatggaagaaaagaaaaagaaaaagcaagaagaaaagaaaaagaaggaagctgctcagaaaaaggctgctgaacagaaaaccaaagtgccagactctgccaagcccagccccacccctcctctccccaacaaccccagcatcgccaccaaccctcccgtgccctcagccagcagcagcactggtggcaatggcaagcgcgcaccctccggcaacaaccaacagcaacagcagccgccggcagcccctcgctacccgcccagagaggtgccccctcgtttccgtcaacacgaacacaagcagctactgaagcgaggccaacctctgcccatcgggagcacagctcttgtgcagcccgcgtccgccagcactacacctcaacccttctcctgccagaccaatccagagctgcccccgcaaagtggcctgacagcgcattatgagaatataccccccagtcgcagtgccactacagcctctactaacagctgcagcagctgggatccactgattattgacgagcgcgatacggaggcttggccatcaatttcatgcaaagaaagccacgttcctgcaggatgccctttggacactgaaagtatcagtgacatcagcagcatgagcatggccactggagctggccagcaaggccatttctccgccaatcacacaagcaaagccaatgtcagccactcaggaggcctgctctctagtcagggtggggccagcagaggctggggctctggccaatctcctgccagtggagaagggaagaatgaagtctccagcacatcagtgggagccaggggttggggctcctctaactttaacttgaacttaaaccctaatgccaacccctctgcctggccagttctggggcatgaagggtctggcatgggtggcggcagctcagggggaagcaaccctcctcctaatctctgtagcccaccgggcactctgcccagccagggctctagcaacagtggcagtataggtggtcccaatggaaattctgcaagtaatggtggcagtggcaatggcagtaccacatggggtagtattatgcccagtgactcctcagagccacactccaccccatccacgaatgtgtctttcagctctgaacctcagaaccttaacactgatggaccaaatcacactaagcaggagcccagaagtcctggtcacagcctgtcaaactggggggttggacctccaggcatgggctcatttgttcaatcccaaggaggatcctcgcaggtcaacggggatagggaacctatttggggtaatggagatgccaagtctggtggtggctcaaaagactctgattgggactcagggcactgggtacaaggaggggcctcgggcacttctggctggggacaagctgcctcatctggtgactggggtaagcattccaacattgacaccaaaggatggaattcttcaggctctcccacccaagaacagcagctaaattcttgggtccgtgggcccaatgccccagctagtgagggaagtagtgacagcatggaatgccatcatcgcaggagggatcgatcatcaagagatgagacttctcctattctgcctgcccaggatatggatcctcgggttttgtgcaacacaggctggggacaaacacctgtgcggcagcatactgcttgggaaaccgaagaagctgctcgctccaaccgcaagaatgacattggaactgaggcctggggctcgtcttcaaatgcagccaatgtaggaccaacatctaattctggcagtgccaacccaaactcaggcactacatccagacctgactctggaggcaagagtgaaggcccctgccctagtactggtgctgcacctggatggggcacagcaatgtcatcaccccaggctggctctggttgggcagatacaaccagcaacaagaaaccttcaattggtcctggagattggggcagcacctcagctggaggcccaggaggcaacctgcagaaaagtggtcagacttggggttcggaagagaagtctccgacctgggaagacagtcacgctaaagccaaaccacagtgctgggttgagggacccaaatctcacgggtggggtaatggacctggtggagaaagtggttctggaggagaatggggtgaacctggagatggaaagaaaaatggtccctccagctctacctgggagggagagggtacaggcttaaatgagggatccagaggatggaccaagccttctgctggagtaggaggaaactggggagaagcacaacgccccagtgtgccaccacaaggatggaataacaagcctcaggagggtaccaatggcaatagcaccagtggaagcatgggttcttggggaggtcctagctcggtaaagcagagttgctctggatggaatggaggaaatggtggaggtgttaaacctgaccacactggagaccccactggatgggaggagccctctccaccctccattcgccgtaagatggagatcgatgatggtacctcagtttggggtgacccaagcacttacaacaaaacagtcaatctctgggacaggaataaccctggaatgcaaggcaaaccaggacctagcaatgccaacaatgtacccaacaaccatcatcatcatccccatcataatcagcctcccatacaatcccacaaccatggagggccaaactcaaacaataatcacatttctcctgataacgctggcccacatcaaacagggccatctcacaatagaacaacccacatgaatccaggatggggagagatgacaaatgcccattcaaaacctgaacctttatggggagagccagcagctcctgctgcaagtgtggacaatggcacttcagcatggggcaaacccccaggtagctgtggcagctggggtgaaaacggccctgaggtctatagccgaggcaatggaccccctggatctgccccctgcaaacctgcccccaaatctatgcaagatagttggggaggtggtgaggacatgggcctgtctgcagggcaatgggagcaggatgagggtgacatgtggaacaacactgcgtctcaggagagcaactcctcctgcagctcctggggcaacccaccgaaaaagggcccaccaaagggaaaagtcacaaacaaacaggatgaaacctggataatgaatcgtctcatcaagcagttgactgacatgggcttccctagagaccctgccgaagaagctcttaagagcaacaacatgaacttggatcaggccatgagcgccctgttagagaagaagacggaactagataaaagggggatgggaatgtctgactacaacaacggcctagtcaataaaccaatgggctgtaggccttcagtcatctccaaagaatcctcctcagatcgaccccctttcctggacaaggatgctgggctagcagatgatgcccaaacctcaccgtttatgccttctccgagcctgaagctcccaatgggtagtgctgcactccctggccagagtctaggagttgccatgcaaaacttgaacaacagacagatgcagagtggagtgtttggtagtagcggagcagcacaagcccgggccctgcagcagcagcctcctccccagccgtcagtgccacctctcaactcgtcccagcctagtctacgcgctcaagtgcctcagtttctcagccctcaggttcaagcacagcttttacagtttgcagcaaaaaacattggtctcaaccctgcacttttaacctcaccaataaaccctcagcatatgaccctgttgaaccaactttatcagctgcaactggcgtaccagcgtttacaaattcagcagcagatgttgcaggcacagcgcagtgtttctggccccatccgacagcaagagcagcaagttgcacgtacaatcaataacatgcagcaacagatccaacagcaccagcggcagctggctcaggctctgctgatgaaacaacagcagcagcagccgcccccctcacacccaggcctgcatcccaatgcaggcaaatcagctctggacacatttccatcccacccccaggcctccagcctctctgtttccgaccttcagaccaaagagccgcagtcttctccaaactccttctcaccctaccctatttctggattaaaccctaacatgaatgtaaactgcatggaagtgggtggcctgtccattaaggattctcctcagcctcagtcacgcctgtcacagtggacacacccaaactccatggataacctctctggcaactcctccccaatggagcccaacttcaacaagcatggtgccatctctgcaggcccaagtttgggtccccctagtaaaccaccactagatgactcctacagtccctacaatctgatttccagctcagattctcctgccagccctctggcacctcacgatagctggggccagggaaagaatgccaatgacaagatctccaatgggaccaatgttaactggcctccagagttttgtccaggagtgccatggaaaggactgcagaatattgaccccgagacagacccaaatgtgaccccagggagtgttcccagcgggcccaccatcaacaccaatattcaggatgtgaaccgctacctgctgagggacaggagtggaggcaagctgtctgacatgaagtccacttggtccccggggcccatctcgcacacccaggcatctctatctcatgagctttggaaagtaccacaagggccccgcaacacgacagctcccacacggccacctccaggcctgaccaacaccaagccctcgtccacatggggaggaaacacacttggtctggtagctagctggggcggctcctactcctcaggtaccacatggagtacagacagctccagcaggagcactagctggctggttttgagaaacctcacacctcagattgatggttcaacactccgaacactgtgcatgcagcacggcccgctcatcacattccatctcaacctgacacagggcaatgctgtggtccgctacagttctaaagaggaggctgccaaagcccagaaatccctacacatgtgtgttctgggaaacaccactatactggcagagtttgctggagaagaggaggtgaaccgcttctttgcacagggtcagtccctaacacccaccaccagctggcaggccaaccctggcaccaatcaaacacggctgggaggcggagggacggcggccacgcaccccatcggccactggaatagcagtagtctgggaggaggaggggccgggacggggtccggcggaaaggcgagcaacgagctgctgtgggggggtgtaccgcagtactccagcctgtgggggccacccagcgctgaggatggccgagttgtcggcagccccaccccaatcaatacgctgcttcctggagacctgctgagcggagagtccatgtgagagtgccaagcgctcgaccccctacggcagcgaaatatgaaacttcacgagcaaaaaccaagcaaatcatttggcgataatcagcgtcagtggaactgtgaaaaccaagagacaggaggctgaggccacacttgcattaaggctgctgaccttcttccttttgtttttgttttgcgtcttttcattggtgttcatttggcttgggttgcagtattctacagacttcttacgaagaatagtgactaaaagagaagtgaacctttaataactgaaaccagtgtgaaagtgtattttactataaactgatgagacaagctgccattttttgaattcctctggcacgagcacatcctgtcagtccaatcacagcatatcggcctgtcccagaagatacgtgtcattccaaaccaacccaccccactctctgtgttttggactggatccatggcgttttttcagttgtcatttggattgtttggattaattaacagcactaaactttagccttaactgctgatcagtcccgctccactccaactctgaagaaactcattttgagaattgcacattttctcatttctgagccaggactgtcaatgggtttgatctcatttacacatttgtccttcctgtttccctcggttgccatcctgtccttgttactctggaaaggacggacaggtatctgacccctctgcacatttattcttgagctgagagaacacgttgaggactacacaaaccactgctcatgaaaaactgtacagacaaactgctctctcttttccattttcctaagcaacctcattctatcaaaagatataagccctcgttgttgtttgtctgacgtgcaatatatgccacagactcttccgtccatctgtacgcagtgctttttttttgccggctaccggtaggagcttgcttggggacgggggaaatcaaagacttgtctcctgccgtgtccaccaagcgtgggactgaacagaagaggactctctcagtgtgtaagcccatggtgatgaaacattcacaagcacttcctctacacacactcaaggacaatgtgtgactacaggggcaacaggggcttcaaaccaaataagaggtgttttcttgtaacccagtagacaaagtgcatttttttgttgttgttgttgttgtatttggtacaaaagtatggaaggaagaaggcgtggtttcttcatagcacttagcaagagcatcaagctccgacttcaatgccaacaaattacacttggatgtgtgaaactgacaaaaagcaacgatgaaaagcaatctaccgaacttctcctccatgctcctttttgaactctaaacggattttgccgtttcttttcttcttctttgtcgtcttctttccacggtctctcgactttgaaatcagacatttcgaaaatggtagcaaaggatgtctgatgaggataaaacaccacaacaagactgaacgttcatgtttttgttttttttttttcttggagatgatatatatcaaagtaaatatcactgttacagtactccaaaatcattagcctttttgtctggagctgatagacatgtaatgtttctaatggattcagtggggccccctgccctggcggccctgcctacctgtatgataagtgtggccattgagtgcctatctgctgtggcacctcaggtgcccacgctctgacttttgacccgctgtgccaggccggcgcaccagatgccagaacggacccacctgggacggagcagtggctccatcagacctggccaatcagtacgtactactactgcgccagcactcgacctcgtctcaacttcactctcatagactctttttctccctctcatgcaaagatcactttagctggaagtggacaggttcgttttatgtacttttttgggtttttcccttctggaattgccagtgttctttttattttgtctgtttgtttggtcaacattgctgttgttatcttcattgctgttgttgttgatgttaaatcatcattttgcgctttttttgtttttcggtttgtgagtgtgtgtgtgtgtgtgtgtatgcgtgtatgtgtgtgtgtcaatgcagtggtctctatggtagctgctctcaccagcccctcttactgcgcatatgcagaaacactctgactaagaggcacacctcagtgtaaacgccgacaatcggcgttggcgattgatatgaaatcactcgttgtgacggaaatgggttgttttttctaagactgaacgcaaagaagagtagtttgatggtgctcagtttgtcttctgcctctcctctgcactttctttctgccacagtcctgccaggccacacgctcacactggtgctttcgacaaagggcaggcagagtacactactttacctggtcgcctcttctcacagtaataaacgcaaaacgataatggagactcggctctccacttctatgcaaaagacaggccgagaggtgcagttcacggccttcagcttcagcttcagtctgtagttctctccaagcccactcttcagcccaccagttcattgtgagaaggcagcttccttccagcgtggcttaaagtaagaaagcggcccgcttcgtttgaacagatgaccaggccctcactgtttactctctgaatgatctcttacattatgtacacgcagtctcagggcagcctcagagaaccccaaactgttgtatcattatgaggagggcgcaaatgtgtgttactgcattatctttcagtatgctaaatacgtggccgagtggacttggagaagattcacaggaagtcccttgtacctaatcttatcgttgacttaacttagatgtgaatctattcgagcgggactccttatatcttgaaatttgatttgtaaagagcacatggagacggagaggtagaatgcagctcggcaccaagacagacgggtagcaccttgtcccaggtatcaaatatgtaggcctgggaggactgctgagaattaaacagggaatccagaatgtttaggtgcactgtagatggttcgcatttgggtacatcttttttttttaaaccaaaaaaggtttatgtctcgttgtgattattgttgttacaaaaggaaactttaattctgtagtacacttttgactgaagtgcttctctctgcaagccttttgacgccccaatgtggcggacagatgactctggggttgctgtattgatggtattaaattctgtcccgaaacggtgcagattactttttatttttcgtcttttaacaggtccaggtccgattggacctattgtatcaggagacctggggcacacgccagttgataccaagtcttataaagggggggaatctcctttctggtagatttttcttttctctttcgtttgttttgtttttaacttcacactcgagtgacactagcaacaatcactattgcctgtttttgaagatatatatatacatatatatttttaactgcctttctctaagctgtactcgagaccacagattgaagaaaaaaaaaaaaaaaaaaacgtccaaaacttgtttaaaatccagaggaatgcctggctgactagctggctagctaacaagtgcccagtcctccattgtgggcatactaggtcttatctataggactaatgtaccccagctccatgagaacgactcagatgcaactttgtgtagatcgtacaaaatatgatgagctctaagaaacacaaatcctctttcttagggccgtggctagaatatgcacatgctggttgatatacatgtacatctgaaatcctgtgtatgtatatgtaactggttcttttgtttgatttttactttattttaaggccccccgttttcttctctccatgaatttacctagaagataagaagcataaacatatcaaaattatacaaataaaaaaaaaactaa

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