LOCUS       NM_214684               2282 bp    mRNA    linear   VRT 28-SEP-2024
DEFINITION  Danio rerio calcium channel, voltage-dependent, gamma subunit 1a
            (cacng1a), mRNA.
ACCESSION   NM_214684
VERSION     NM_214684.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 2282)
  AUTHORS   Cai,W., Wang,Y., Luo,Y., Gao,L., Zhang,J., Jiang,Z., Fan,X., Li,F.,
            Xie,Y., Wu,X., Li,Y. and Yuan,W.
  TITLE     asb5a/asb5b Double Knockout Affects Zebrafish Cardiac Contractile
            Function
  JOURNAL   Int J Mol Sci 24 (22), 16364 (2023)
   PUBMED   38003559
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2282)
  AUTHORS   Mao,K., Li,X., Chen,Z., Dong,X., Zhangsun,D., Zhu,X. and Luo,S.
  TITLE     alpha-Conotoxin TxIB Improved Behavioral Abnormality and Changed
            Gene Expression in Zebrafish (Danio rerio) Induced by Alcohol
            Withdrawal
  JOURNAL   Front Pharmacol 13, 802917 (2022)
   PUBMED   35177988
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2282)
  AUTHORS   Lee,J., Horzmann,K.A. and Freeman,J.L.
  TITLE     An embryonic 100mug/L lead exposure results in sex-specific
            expression changes in genes associated with the neurological system
            in female or cancer in male adult zebrafish brains
  JOURNAL   Neurotoxicol Teratol 65, 60-69 (2018)
   PUBMED   29074346
REFERENCE   4  (bases 1 to 2282)
  AUTHORS   Han,Y., Qian,J., Zhang,J., Hu,C. and Wang,C.
  TITLE     Structure-toxicity relationship of cefoperazone and its impurities
            to developing zebrafish by transcriptome and Raman analysis
  JOURNAL   Toxicol Appl Pharmacol 327, 39-51 (2017)
   PUBMED   28465218
REFERENCE   5  (bases 1 to 2282)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2282)
  AUTHORS   Todd,P.K., Ackall,F.Y., Hur,J., Sharma,K., Paulson,H.L. and
            Dowling,J.J.
  TITLE     Transcriptional changes and developmental abnormalities in a
            zebrafish model of myotonic dystrophy type 1
  JOURNAL   Dis Model Mech 7 (1), 143-155 (2014)
   PUBMED   24092878
REFERENCE   7  (bases 1 to 2282)
  AUTHORS   Williams,C.M., Feng,Y., Martin,P. and Poole,A.W.
  TITLE     Protein kinase C alpha and beta are positive regulators of thrombus
            formation in vivo in a zebrafish (Danio rerio) model of thrombosis
  JOURNAL   J Thromb Haemost 9 (12), 2457-2465 (2011)
   PUBMED   21951302
REFERENCE   8  (bases 1 to 2282)
  AUTHORS   Woods,I.G., Wilson,C., Friedlander,B., Chang,P., Reyes,D.K.,
            Nix,R., Kelly,P.D., Chu,F., Postlethwait,J.H. and Talbot,W.S.
  TITLE     The zebrafish gene map defines ancestral vertebrate chromosomes
  JOURNAL   Genome Res 15 (9), 1307-1314 (2005)
   PUBMED   16109975
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC044150.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC044150.1, GW709681.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505374 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2282
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="AB"
                     /db_xref="taxon:7955"
                     /chromosome="6"
                     /map="6"
     gene            1..2282
                     /gene="cacng1a"
                     /gene_synonym="cacng1; wu:fb43f02; wu:fi19g08; zgc:55364"
                     /note="calcium channel, voltage-dependent, gamma subunit
                     1a"
                     /db_xref="GeneID:322013"
                     /db_xref="ZFIN:ZDB-GENE-030131-732"
     exon            1..391
                     /gene="cacng1a"
                     /gene_synonym="cacng1; wu:fb43f02; wu:fi19g08; zgc:55364"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    70..72
                     /gene="cacng1a"
                     /gene_synonym="cacng1; wu:fb43f02; wu:fi19g08; zgc:55364"
                     /note="upstream in-frame stop codon"
     CDS             157..834
                     /gene="cacng1a"
                     /gene_synonym="cacng1; wu:fb43f02; wu:fi19g08; zgc:55364"
                     /note="calcium channel, voltage-dependent, gamma subunit
                     1"
                     /codon_start=1
                     /product="calcium channel, voltage-dependent, gamma
                     subunit 1a"
                     /protein_id="NP_999849.1"
                     /db_xref="GeneID:322013"
                     /db_xref="ZFIN:ZDB-GENE-030131-732"
                     /translation="

MRKETKTKVLFFVILVGSVCMLTAVVTDHWAVLSPRVETINTTCEAVHFGLWKLCKKHIYIEDKEYIGKPCGPISLPGEMNCSYFRHFTPGEDSEIFEVKTQREYNISGAAIALFSLAFVILGTLCVLCSLKKGKDYMYKPAGMFFAFAGLCAFISVEVMRQSVLRMIASEHTIWIEYYYSWSFACACTGFVLLLLSGIGLVLVSMPQMPRNPWESCMDAEPEQM"

     misc_feature    199..753
                     /gene="cacng1a"
                     /gene_synonym="cacng1; wu:fb43f02; wu:fi19g08; zgc:55364"
                     /note="PMP-22/EMP/MP20/Claudin tight junction; Region:
                     Claudin_2; pfam13903"
                     /db_xref="CDD:372799"
     exon            392..466
                     /gene="cacng1a"
                     /gene_synonym="cacng1; wu:fb43f02; wu:fi19g08; zgc:55364"
                     /inference="alignment:Splign:2.1.0"
     exon            467..604
                     /gene="cacng1a"
                     /gene_synonym="cacng1; wu:fb43f02; wu:fi19g08; zgc:55364"
                     /inference="alignment:Splign:2.1.0"
     exon            605..2261
                     /gene="cacng1a"
                     /gene_synonym="cacng1; wu:fb43f02; wu:fi19g08; zgc:55364"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ttttatccatgcacaagctgcactgagcccttgataatcaagaactggaccagatctctgtttcatatataaaaaccagagattcctttgctaaaagaattactatcaagtaattatttattttatctgttaattggcaagtggatactggacaaaatgcgtaaggagaccaagacaaaagtcttattttttgtgatcttggtgggctcggtgtgcatgcttacagcagtggtgacagaccactgggccgttttgagtcctcgagtggaaacaataaacacaacatgtgaggcagttcacttcggcctttggaaactttgtaaaaaacacatctatattgaggataaggaatacattggtaaaccctgtggacccattagcttacctggagaaatgaactgttcttacttcagacacttcacgccaggggaagattctgagatctttgaagttaaaactcagagagaatacaacatctcaggtgctgccatagccctcttcagtcttgcctttgtgattctgggcactctgtgtgtgttgtgttctctcaaaaagggaaaagactatatgtacaagcctgccggcatgttcttcgcttttgcaggtctgtgtgccttcatatcagtagaggtaatgcggcagtcagtcttgaggatgatagccagcgagcatacaatctggattgagtattattattcctggtcttttgcttgcgcctgcacgggttttgtcctgctcctcctcagtggaatcggtctggtgctggtctccatgccacagatgcctagaaatccatgggaaagctgcatggacgctgagcctgaacagatgtagattaggaaaagcagatgccagaaggtaaaccactgcctcgccaaataggcctctttgatacagtaagagtgctcgacaaacagatgtcataaaactagcttagcaacttccttgtttcccccacaaagtggcatgaagaatataaatgtgccacacattcttgtcatgcaagcaagtagctaagcttttcagtctactattattatcatcatcatcgagtatccatgtttaaaaacatgatgtataaaatctctaaaatgcaatatgaagagtgcagctggcattgtgaattttgagtaatgatgtggtgatttaaatggagaagggttgcataagtattgtgtttgctataacattttgaaggaacgaaggaaggatttatgtttaacaacatatttcaaggattatgtactgttggttaatttgcactagcttgcaaataggtaattcaaacatcaacaagcaatgacgtaatgccacaagattttgctttacagatagcatcagtcatgtcttgtaaattaatttagatttgtttagaagtaaaaattctacttttttcccttgatttttattctagtcattttaaagtactttacttttgcctttttgcccttttggacacagtgatgctctgaactgctctgagcagaatgcaaatgcttggtctgctgcggttgctgaatgcttggccagacattttagaatattttcagatcttgcaggtgcaaagaaaatggcatcaatctaactcttatgtgaagctgtaaaatatctctgagatcgtccaagtctatggcttcctgaaatgcacccgcagacaagtctgaaacagataggcatttagtcatttctgtgtaaagtctgtagaaaatgtttcgctttgtatttatgctaagcagactttcttttgtacattataattagcaacaataaatagtttaatttggtaacttgcaactaatttctctctctcaggacattttgtaaactgtcttagaaatgcccttcatgatatctaaaaaaagatattaaaatacaagataataaatttggtgtcacttatacaattttatcaggccttttgccatttaaattagatgttatactcagtggataataagctaaatacaaacaaaatggcagacaacaaataaaaaagcacctgtaaaaatattggaaacaaaatgaaagaaacaaggaaagttagttttgggttttgtggtggctgttagaatgtacctttatatcccaattactacatgatgaggcaaatgcttcaatcaagtttattttgacaggaaatactgtatttatttcttttgttgttgtgcgcatgcagaacaagcatatctgctcaacagaatatctgtatttctgatgttgcaaacccatgttgtgtatttttaataaaacaaataagccaaaaaaaaaaaaaaaaaaaaaaa

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