LOCUS       NM_201463               1873 bp    mRNA    linear   VRT 16-SEP-2024
DEFINITION  Danio rerio peter pan homolog (ppan), mRNA.
ACCESSION   NM_201463
VERSION     NM_201463.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1873)
  AUTHORS   Parvez S, Herdman C, Beerens M, Chakraborti K, Harmer ZP, Yeh JJ,
            MacRae CA, Yost HJ and Peterson RT.
  TITLE     MIC-Drop: A platform for large-scale in vivo CRISPR screens
  JOURNAL   Science 373 (6559), 1146-1151 (2021)
   PUBMED   34413171
REFERENCE   2  (bases 1 to 1873)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1873)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1873)
  AUTHORS   Liu X, Jia X, Yuan H, Ma K, Chen Y, Jin Y, Deng M, Pan W, Chen S,
            Chen Z, de The H, Zon LI, Zhou Y, Zhou J and Zhu J.
  TITLE     DNA methyltransferase 1 functions through C/ebpa to maintain
            hematopoietic stem and progenitor cells in zebrafish
  JOURNAL   J Hematol Oncol 8, 15 (2015)
   PUBMED   25886310
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1873)
  AUTHORS   Recher G, Jouralet J, Brombin A, Heuze A, Mugniery E, Hermel JM,
            Desnoulez S, Savy T, Herbomel P, Bourrat F, Peyrieras N, Jamen F
            and Joly JS.
  TITLE     Zebrafish midbrain slow-amplifying progenitors exhibit high levels
            of transcripts for nucleotide and ribosome biogenesis
  JOURNAL   Development 140 (24), 4860-4869 (2013)
   PUBMED   24198278
REFERENCE   6  (bases 1 to 1873)
  AUTHORS   Anderson RM, Bosch JA, Goll MG, Hesselson D, Dong PD, Shin D, Chi
            NC, Shin CH, Schlegel A, Halpern M and Stainier DY.
  TITLE     Loss of Dnmt1 catalytic activity reveals multiple roles for DNA
            methylation during pancreas development and regeneration
  JOURNAL   Dev Biol 334 (1), 213-223 (2009)
   PUBMED   19631206
REFERENCE   7  (bases 1 to 1873)
  AUTHORS   Kubota Y, Oike Y, Satoh S, Tabata Y, Niikura Y, Morisada T, Akao M,
            Urano T, Ito Y, Miyamoto T, Watanabe S and Suda T.
  TITLE     Isolation and expression patterns of genes for three
            angiopoietin-like proteins, Angptl1, 2 and 6 in zebrafish
  JOURNAL   Gene Expr Patterns 5 (5), 679-685 (2005)
   PUBMED   15939380
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC045506.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC045506.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505370, SAMEA3505375
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1873
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="AB"
                     /db_xref="taxon:7955"
                     /chromosome="3"
                     /map="3"
     gene            1..1873
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /note="peter pan homolog"
                     /db_xref="GeneID:317739"
                     /db_xref="ZFIN:ZDB-GENE-030114-4"
     exon            1..148
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    122..124
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /note="upstream in-frame stop codon"
     CDS             134..1702
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /codon_start=1
                     /product="suppressor of SWI4 1 homolog"
                     /protein_id="NP_958871.1"
                     /db_xref="GeneID:317739"
                     /db_xref="ZFIN:ZDB-GENE-030114-4"
                     /translation="

MGKNKTKNQKKARGDATRVAEESYSTVPHTFVFHRGQVGKNVGQLMLDMRRVMEPFTARSLKVRKKNVLKDFVAVAGPLGITHFSIFTKTENTVNMRPARLPKGPTLYFRVAKYTLIKDNISSLKRHRMHEQQFSHHPLLVLNNFGVEGMQVKLMATMFQNMFPSINIHQLNLNCIKRCVLLNYDPVSQEVEFRHYSLKVVPVGMSRGVKKLMQEKFPNMSKLEDISELLMKGVNLSESEAEQDEEHNITELPQVYSGRGNMASQQSAVRLTEIGPRMTLQLVKIVEGMGEGSVLYHSIVSKTEEQIQEMLKRKEKHLKLKEERKRKQEKNIAMKKEQRDLNKKRSLEGIKRKREQEGQGSDNEVEDPGMQEGQAPAEESDDEAEYYRQAVGEEPDEDMFPGAKRKHRPGKSPNPFKKRKMSPGKGLPPHDKKSFKSGDRGKKAAGKQFGYKKTLEGRSQFKKSGGGKKFVKREEKGNRFGQKKGESGKRFGVKKTFKGRSTTKQQRGSGGRKDFKHKKGKS"

     misc_feature    224..733
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /note="The Brix domain is found in a number of eukaryotic
                     proteins; Region: Brix; smart00879"
                     /db_xref="CDD:214879"
     misc_feature    <938..1153
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /note="The Brix domain is found in a number of eukaryotic
                     proteins; Region: Brix; cl00935"
                     /db_xref="CDD:469999"
     exon            149..319
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     exon            320..421
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     exon            422..472
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     exon            473..643
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     exon            644..720
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     exon            721..828
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     exon            829..952
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1031
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1161
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1325
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1857
                     /gene="ppan"
                     /gene_synonym="cb642"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

acatggctacacaggattttcaagatggacgtagtttaaaaaggcttgtgagatattttagctgagattttcgaattaaaaacagttttagctttccaccatcgacagggaaaggtcatactgaccttacaatatggggaaaaataagactaagaaccagaagaaagcccgtggagatgcgacacgtgtggcggaggagagttactcaactgtcccgcacacattcgtgtttcaccgcggacaggtcggcaagaatgtcggacagctgatgctggacatgagacgggtcatggagcctttcactgccagatctctaaaggtacggaagaaaaacgtcttgaaagattttgttgctgtggccggaccgttaggaatcacacacttctcaatatttaccaaaacagaaaatactgtaaacatgaggcctgcacgacttcccaaaggtccaacgttatatttccgtgttgcaaagtacacactcatcaaagataacatttcatcattgaaaaggcacagaatgcatgaacagcagttttcccatcatcctttgctggtactgaataattttggcgtagaaggcatgcaggtcaagctgatggccaccatgttccagaatatgttcccctcaatcaacatacaccagctcaacctcaactgtataaagagatgtgtgctgttaaattacgatccggtgtctcaggaggtggagtttcgtcattatagtttgaaggtggttcctgtgggcatgagtagaggggtgaagaagctcatgcaggagaagttccccaacatgagcaagctggaggacatcagtgagctcctcatgaaaggtgtaaacctttcagaaagcgaggcagagcaggatgaggagcacaacatcacagagttaccccaagtgtactctggccgagggaacatggcgtctcagcagagtgcagttcggctgacagagattggccccagaatgactttgcagctggtcaagatagtagaaggcatgggagaaggaagcgtgctttatcattccatcgtctcaaaaaccgaagagcagattcaggagatgctaaaaaggaaggagaagcatctgaaactgaaagaagagcggaagagaaagcaagaaaaaaacattgccatgaaaaaagaacagcgtgatctaaacaaaaaacgaagcttggagggcatcaagagaaagcgggagcaggaaggccagggttcagataatgaagtggaggatcctgggatgcaggagggccaggctccagcagaggagtctgatgatgaagcagagtattacagacaggctgtaggagaggaaccagatgaagacatgtttcctggagcaaaaaggaaacaccgccctggcaagtcaccaaaccccttcaaaaagaggaagatgtcaccggggaagggccttcctccacatgataagaagagttttaagtctggtgaccggggaaagaaagctgctgggaagcagtttggctataagaagacactggaaggaaggagccagtttaaaaagagtggaggcggcaagaaatttgtcaaaagagaagagaaggggaataggtttggccagaaaaaaggagaaagcggtaagaggtttggtgtaaagaaaacctttaaaggacggtcaacaacgaaacaacaaagaggctctggaggaagaaaagactttaaacacaagaaaggaaaaagctgaaggaagtgaaagcgcaaagtttaaagagctgaaccagaaggtggaactgttgtttcataactgatgtgccatctctacgctgaaaaatgtcaaaattgtcccttgtatatatttatagagttggttgcattcaccaataaataaatcgtcaagtaaaaaaaaaaaaaaaaa

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