LOCUS       NM_001080674            1758 bp    mRNA    linear   VRT 16-SEP-2024
DEFINITION  Danio rerio tripartite motif containing 62, tandem duplicate 1
            (trim62.1), mRNA.
ACCESSION   NM_001080674
VERSION     NM_001080674.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1758)
  AUTHORS   Cao M, Wang N, Yan X, Yang N, Fu Q, Zhang X, Zhang Y and Li C.
  TITLE     Structures, evolutionary relationships and expression profiles of
            the tumour necrosis factor superfamily and their receptors in black
            rockfish (Sebastes schlegelii)
  JOURNAL   Dev Comp Immunol 132, 104405 (2022)
   PUBMED   35364135
REFERENCE   2  (bases 1 to 1758)
  AUTHORS   Kossack ME, High SK, Hopton RE, Yan YL, Postlethwait JH and Draper
            BW.
  TITLE     Female Sex Development and Reproductive Duct Formation Depend on
            Wnt4a in Zebrafish
  JOURNAL   Genetics 211 (1), 219-233 (2019)
   PUBMED   30446521
REFERENCE   3  (bases 1 to 1758)
  AUTHORS   Hu YW, Wu XM, Ren SS, Cao L, Nie P and Chang MX.
  TITLE     NOD1 deficiency impairs CD44a/Lck as well as PI3K/Akt pathway
  JOURNAL   Sci Rep 7 (1), 2979 (2017)
   PUBMED   28592872
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1758)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1758)
  AUTHORS   Boudinot P, van der Aa LM, Jouneau L, Du Pasquier L, Pontarotti P,
            Briolat V, Benmansour A and Levraud JP.
  TITLE     Origin and evolution of TRIM proteins: new insights from the
            complete TRIM repertoire of zebrafish and pufferfish
  JOURNAL   PLoS One 6 (7), e22022 (2011)
   PUBMED   21789205
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC129354.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC129354.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505372 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1758
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="11"
                     /map="11"
     gene            1..1758
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /note="tripartite motif containing 62, tandem duplicate 1"
                     /db_xref="GeneID:791192"
                     /db_xref="ZFIN:ZDB-GENE-070112-502"
     exon            1..151
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /inference="alignment:Splign:2.1.0"
     exon            152..684
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    268..270
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /note="upstream in-frame stop codon"
     CDS             277..1704
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /EC_number="2.3.2.27"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRIM62"
                     /protein_id="NP_001074143.1"
                     /db_xref="GeneID:791192"
                     /db_xref="ZFIN:ZDB-GENE-070112-502"
                     /translation="

MASYLKDELLCSICLSIYQDPVSFGCEHYFCRKCITEHWSRQEHHGTRDCPECRRTFTDPLLSPSLKLSNIVERYTAFPLDAILNAQRNSYPCKDHEKVKLFCLSDKSLVCFFCDEPALHEQHQVTTVDVAYEEIQREMKEQLATLQDSEKGHTEALQLLQRQLTETKSSAKSLRATIGEAFERLQRFLRERQKSMLEELEADTARTLTDIEHKIQRYSQQLRDVKEGIQILQERLSETSRHEFLEGIALTSDRIKGKIHETNLTYEDFPTSKYMGPLQYTIWKSLFLDISPVPAALTMDPSTAHQRLILSDDCTIVAYGNLHPQPLQDSPRRFDVEVSVLGDEGFSGGVHYWEVMVSEKTQWMIGVANETVNRKGSIQIQPGRGFYCIVMHDGNQYSACTEPWTRLNVKSKLEKVGVYLDYPKGLLVFYNADDMSWLYTYREKFPAKLFPYFSPGQSHANGKNVQPLRINTVRL"

     misc_feature    283..447
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /note="RING finger, HC subclass, found in tripartite
                     motif-containing protein 62 (TRIM62) and similar proteins;
                     Region: RING-HC_TRIM62_C-IV; cd16608"
                     /db_xref="CDD:438270"
     misc_feature    547..660
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /note="B-box-type 2 zinc finger found in tripartite
                     motif-containing protein 62 (TRIM62) and similar proteins;
                     Region: Bbox2_TRIM62_C-IV; cd19792"
                     /db_xref="CDD:380850"
     misc_feature    682..1011
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /note="coiled-coil (CC) domain of Drosophila brain tumor
                     (brat) and similar proteins; Region: CC_brat-like;
                     cl29238"
                     /db_xref="CDD:475168"
     misc_feature    1126..1689
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /note="SPRY domain; Region: SPRY; cl02614"
                     /db_xref="CDD:470632"
     exon            685..780
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /inference="alignment:Splign:2.1.0"
     exon            781..1037
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1153
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1754
                     /gene="trim62.1"
                     /gene_synonym="trim62; zgc:158653"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gattgtgaaaagctgcgcgtgcggtcggtcggtcgcttcagcttttgaagggtctgacgtgatgaaaatgttgaattaaaaccacgacccgctctcctaattatgtgacagtcggctgcttccagtgtacaacgcgccaggaccgttttggaaaatttcatcggagtcattttcaagcctcgcagagcacactaggaagcccagctgcttgagaggctcagggtttgtgcatcccgccacctgcacagtgcatgaccgactcctccatagattcaaatggctagctacctgaaggacgagctcttgtgttctatttgtctgagcatttatcaagaccccgtgagtttcggttgcgagcactacttttgccgtaagtgcatcactgaacactggagcagacaggagcatcacgggacacgagactgcccagagtgcaggaggaccttcacggatccccttctatcgccaagcctcaagctctccaacatcgtggagaggtacaccgctttccccctggacgccatcctcaatgctcagaggaactcgtatccgtgcaaagaccatgaaaaggtcaagctcttctgcttaagtgacaagagcctggtgtgcttcttctgtgatgagcctgcattacacgaacagcatcaagtcaccacggttgacgtggcctatgaggagatacagagggagatgaaggagcagctggcgactcttcaggacagtgagaagggtcatacggaggctttacaactactgcagaggcagcttactgaaaccaagtcatcagcaaagagtcttcgtgccacgattggcgaggcatttgagcgacttcagcgttttctccgggagcggcagaagagcatgctggaggaactggaggcggatacggcgcgaacactcactgacattgaacacaagatccagcgctacagccagcagctccgcgacgtcaaagagggcatccagatcctgcaggagcgactcagtgaaactagccgtcacgaattcctggagggaatcgccctgacgtcggacagaataaagggaaaaatccacgaaaccaacctcacctacgaagacttccccacatccaagtacatggggcccttacagtatacgatctggaagtctcttttcttggatatttcaccagtgcctgctgcattaaccatggaccccagcactgctcaccagcggctcatcttatcagacgactgcaccatcgtggcgtatggcaacctgcatccgcagcccttgcaggattcaccacgccgattcgacgtggaggtgtccgttctgggcgatgaaggcttctccggaggcgtccactactgggaggtaatggtgtccgaaaaaacccagtggatgattggtgtggccaacgaaacggtcaaccgcaagggcagcattcaaatccagcccggccgaggcttctactgcatcgtgatgcatgacggtaatcaatacagcgcctgcacagagccctggacgcgcctcaacgtcaagagcaaactggaaaaagtgggcgtctacttagactatcctaaaggcttgctggttttctacaacgctgacgacatgtcctggctgtacacgtacagagagaagtttccagccaaactcttcccatacttcagccccggtcaaagtcacgccaacggcaaaaacgtgcagcccttgcgaataaacacagtgcgtttataaaagccgattcagcacagaggttttaaggaaggaaactgcaaaaaaaaaaaaaaa

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