LOCUS       XM_018817357            3923 bp    mRNA    linear   INV 22-OCT-2018
DEFINITION  PREDICTED: Ciona intestinalis protein argonaute-2 (LOC100181160),
            transcript variant X2, mRNA.
ACCESSION   XM_018817357
VERSION     XM_018817357.2
DBLINK      BioProject: PRJNA187185
KEYWORDS    RefSeq.
SOURCE      Ciona intestinalis (vase tunicate)
  ORGANISM  Ciona intestinalis
            Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
            Cionidae; Ciona.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_020167.2) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 22, 2018 this sequence version replaced XM_018817357.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Ciona intestinalis Annotation
                                           Release 104
            Annotation Version          :: 104
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.1
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3923
                     /organism="Ciona intestinalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:7719"
                     /chromosome="2"
     gene            1..3923
                     /gene="LOC100181160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 255 ESTs, 4 Proteins, and 97%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 199 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:100181160"
     CDS             247..3012
                     /gene="LOC100181160"
                     /codon_start=1
                     /product="protein argonaute-2 isoform X2"
                     /protein_id="XP_018672902.1"
                     /db_xref="GeneID:100181160"
                     /translation="

MKFTENNLSNPMYQPTGPGQPILPQYGALAGGVPPPQGPAPPGVPPNPMQQAPPAQLIPPNGRPTMDPRFPIATVARDIDFQAPPRPNQGQVGKPIWLKANYFKVSIPNGDIHHYDIDIKPDKCPRRVNREIINTMVENFRSAIFQDRKPVFDGRKNLYTAQPLPIDKQKLEVEVTLPGEGRDRTFTVAIKWASRVSLYSLKLALEGKMHGIPFETVQSLDVVMRHLPSLRYTPVGRSFFSAPEGYTPPLGGGREVWFGFHQSMRPSQWKMMLNIDVSATAFYRAQSCVQFLCDVLELRIEDLRLIRGLTDSQRVKFTKEIRGLKVEITHCGTMRRKYRVCNVTRRAASTQTFPLQLESGQTIECSVARYFQEKHSKTLQFPFLPCLQVGQEQKHTYLPIEVCNIVQGQRCIKKLTDSQTSTMIKATARSAPDREKEIAQLVRKAQFNNDPYVKEFGIQVIDEMTEVRGRVLPPPKIQYGGDPLMQATPNQGVWDMRGKQFHSGISIDVWAIACFAHQRMCSDQHLRTFIKSLQRISEDAGMPIRGTPVFCKYAQGSEHVEPLFRHLCDEFRALQLIVVILPGKTPVYAEVKRVGDTLLGIATQCVQVKNVVKTSPQTLSNLCLKINVKLGGVNNILVPSLRPKVFNDPVIFFGADVTHPPAGDTRKPSIAAVVGSMDAHPSRYSATVRVQQHREEIIRDLAIMVRDLMVEFYKATHYKPVRVIMYRDGVSEGQFQQVLSTELRAIREACTMLEVGYQPGITFIVVQKRHHTRLFCRNHEDRSGKSGNIPAGTTVDIGICHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNNFMADELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKDHDSGEGSLQSGHTQHDQDAQLQAMSKAVVVHENTVRNMYFA"

     misc_feature    403..3006
                     /gene="LOC100181160"
                     /note="protein argonaute; Provisional; Region: PLN03202"
                     /db_xref="CDD:215631"
     misc_feature    1597..2874
                     /gene="LOC100181160"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2008..2010,2020..2022,2056..2067,2074..2076,
                     2098..2100,2107..2109,2119..2121,2131..2133)
                     /gene="LOC100181160"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2212..2214,2218..2220,2428..2430,2842..2844)
                     /gene="LOC100181160"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

aagtggactggcgtggtaacacgaggtacttagtgaaagacgagttctatattgtaatgaatattaattagtgaaagacgagttctatattgtaatgaatattaatttatttactgtttctgattaatgcataattacgttacagaaagttttagtgtgtatttttttctttataaaaagttttactaaaatttgcatcgctactggcgtcaaacgtcggtaccttgcccctggacactgccttttatgaagttcaccgagaacaatttgagtaatccaatgtatcagccgacgggtccgggccagccaatattgccacaatatggcgccctggcagggggggttccaccaccacagggtcctgccccacctggagtcccacccaaccccatgcagcaagcaccacctgcccagctgattccaccaaacggaagacctacaatggaccctcgcttccccatcgctactgtggcacgcgatatcgacttccaagctcctcccagaccaaaccaaggtcaagttgggaaaccaatctggttaaaagcaaactactttaaagtttccattcctaatggagatattcatcattatgatattgatattaaacctgacaagtgtccacgacgagtaaacagagagattattaacacgatggtagaaaactttcgttcagctatttttcaagatcgtaaacctgtgtttgatggacgcaagaacctatacacggcacaacctcttccaattgataaacagaagcttgaagttgaagttacattgcctggtgaaggcagagatcgtacatttactgtggcaatcaagtgggcatctagggtttccctttattctctcaagcttgcacttgaaggaaaaatgcatggcattccatttgaaacagtacagtctcttgatgtagtgatgcgtcatttgccatcactaagatacacccctgttggtcgatctttcttttcagcgccagaaggctacacccctccacttggtggtggtagagaggtgtggtttggatttcatcaatccatgcgcccatcacaatggaaaatgatgcttaacatcgatgtgtcagccactgctttctatcgggctcaatcatgtgttcaattcctttgtgacgttcttgaactaagaattgaagatttgagattgatcagaggtttgacagactcacagcgtgttaagttcacaaaagaaattcgtggattgaaggttgagataactcactgtggaacaatgcgtcgtaaatatcgtgtatgtaatgtgacaaggagagctgcttctacacaaacattcccacttcagttggaatctggtcaaaccattgaatgttctgttgccagatatttccaggaaaaacattcaaagactctgcagtttcccttccttccttgtttgcaagttggccaggaacaaaagcacacctaccttccaattgaagtatgtaatatcgttcaaggtcaaagatgtattaaaaaattaactgacagccaaacctcaacaatgatcaaggctactgcacgttcagcaccagatcgggagaaagaaattgcgcagttggttcgcaaagctcagtttaacaacgatccttatgtgaaggagtttggaatacaggttattgatgaaatgactgaggttcgtggaagagtgcttccaccacccaagattcaatatggtggagatcctctaatgcaagctactccaaaccaaggtgtgtgggatatgaggggaaaacaattccattctggtatcagcatagatgtgtgggcaatcgcttgttttgctcatcagagaatgtgctcggaccaacatttacgaacattcatcaagagtttgcaacgtatatcggaagatgctggcatgccaattcgtggcacccccgtcttctgtaaatatgcacaaggttctgagcatgttgaaccattgttcaggcacctgtgcgatgagttccgtgccctgcagttaattgttgttattctacctggcaaaactccagtatacgctgaggtaaagagagttggggatactctgcttggtattgctacccagtgtgtacaggtcaagaatgtggtaaaaacatcacctcaaactctttccaacctttgcttgaagatcaatgtgaaacttggtggtgttaataacatccttgttccatcactgaggccaaaggtatttaatgatcctgtaatattctttggtgctgatgttactcacccaccagctggagatacaagaaaaccttccattgctgctgttgtgggtagcatggatgcccacccatctcgttatagtgccacagtgagggtgcaacaacatcgagaagaaataatccgtgatcttgccatcatggttcgtgatctgatggtggaattttacaaagcaactcattataaacctgttagagttatcatgtacagagatggagtatctgaagggcagtttcaacaggtgctgtcaacggagcttcgtgccattcgtgaagcttgcacaatgcttgaggttggttaccaacctggcattacattcattgtggtacagaagcgacatcatactcgtctattttgtcggaatcacgaggacaggagtggtaaaagtggaaacataccagctggaaccactgttgatattggtatctgccatccaactgagtttgacttttacctctgcagtcatgctggtattcagggcacatccagaccctcgcattaccatgtgttatgggatgataataacttcatggctgatgagcttcaagttcttacctatcaactttgccatacatacgttcgctgcaccagatccgtatctatacctgccccagcatattatgctcacttggtggcgttcagagctcgttatcacttggtggacaaagaccacgacagtggtgaaggttccttacaaagtggacatacacaacacgatcaagatgcacagttgcaagccatgtccaaggcagttgttgtacatgagaatactgtgaggaacatgtactttgcatgagtgcattcaactacattagctcaagttttgcatgtttttaggaaaatctctgtttttgagtgttttatctaatttcattctattttatgcgatgaacagagtgctttccacacttgtagaatatgaacaataattaaactgtgataactccccacgatcaagtgtggttgtgagcaaatcatgttaatggtgtaaaccaccatttaattgtctgtacttaccaagttcacctaatatatataaacacatattgtaaaaaacctgattgtcattgtattcatccttactagattgtacaaaccataatatccaacatagctactacatatgtacaaaattgtacagtatgcgttatcccccttatactaatgattaataaaatgtacagcagtaaggataaacaaattgattccaaaattgactgtttatgttcgttcatttatgctgcgtgttgtgaagcagcagaaagttcttgtttgatcaatgcttgccaccgtggtgtttttatacaaggcgctgggttgccagacaaaagtgaacccatagcaaccaccgaaacccaaagaggttgcttacctgcgtatgaccgtgtcatcgcggaccttttgtctggcaagtataaccagtgcctgtaatggtttcctcaaaagattgtaaatgtgtaattacttgtcaatcctttgtactctgtacatattcttttactgtacatacacttcagtcgcatacaaaccataacaattccaactgtataatattaatctaaactttattttgtattgttgtgttatacaaccattttagaataactttttaacacaaaaataggcggaaattataatgaaactcctggagtagctgcttgtaaacatagcgcttgatgaaatgtaaataaaatgttaatcaattaa

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