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2024-11-01 08:25:41, GGRNA.v2 : RefSeq release 226 (Sep, 2024)

LOCUS       XM_002130541            4859 bp    mRNA    linear   INV 22-OCT-2018
DEFINITION  PREDICTED: Ciona intestinalis piwi-like protein 2 (LOC100181639),
            mRNA.
ACCESSION   XM_002130541
VERSION     XM_002130541.5
DBLINK      BioProject: PRJNA187185
KEYWORDS    RefSeq.
SOURCE      Ciona intestinalis (vase tunicate)
  ORGANISM  Ciona intestinalis
            Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
            Cionidae; Ciona.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_020176.2) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 22, 2018 this sequence version replaced XM_002130541.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Ciona intestinalis Annotation
                                           Release 104
            Annotation Version          :: 104
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.1
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4859
                     /organism="Ciona intestinalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:7719"
                     /chromosome="11"
     gene            1..4859
                     /gene="LOC100181639"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 27 ESTs, 15 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 32 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:100181639"
     CDS             128..2932
                     /gene="LOC100181639"
                     /codon_start=1
                     /product="piwi-like protein 2"
                     /protein_id="XP_002130577.2"
                     /db_xref="GeneID:100181639"
                     /translation="
MDKFNLPSVGRGRGLSVLKLLQEKSDSEAKSEECGSTTTLAAGDNTGVDSAVSKLSLTSSLGRGQTVGLIGRGQALSPPFQLQGAAGRGQMSFLSKGRGSALLQELGIGKSAEALKPCESLPVVLREKTPEVELKKQKTLTTQPQSIAQPSITSQDITKVDEVVKYHGQSGRRNDIRVNCVRVKCINLAVYQYHVSFEPVVDSRNMRFMLLNQHREVIGNTKAFDGTILYLPMKLELNELRLKSKRVTDEADIVVLIRFTKAIDPASSQLIPFYNTVLKRCMRLLDMCPVGRNYYDPTSPKTIEKLQLILWPGYVTAIKKFEDGLMLNIDVSHKVLRQDTAKHVMVEAYKRSPNQYRDACVKELVGAIVLTRYNNKNYRVDDIAWDMTPSSSFTNSKGDKLTFVEYYKVQYKIEITDLKQPMLVHRPKKQTQRDFKRNEGEDYCICLVPELCYLTGLSDKLRSDFRAMREIRDNTSFDPTRRNACLEEFLKRVNMNTNAKNELLRWGLELDMKTCSTFSRSLPSEKIMVGRNQVFSCGPDADFGREVTRSPVITPIPINNWLLVFVKRDSNKAENFFQKMMECTRKLGIDLSKPRFLQLNDDRTTSYKDAISQSLNPSTQLVVCIFPTSRDDRYNAIKKLCCVDMPVPSQVIISRTLPDDAKMGKFRSVTMKIALQINCKLGGELWTVDIPLKGLMVCGIDVYHDPLKRGKSVAAFIASSNRLMSTWFSKAIIQQPHQELIDSLKQCFVNALKNYYELNHALPERIVIFRDGVGDGQLNIVAEHEVVQLQSCFEMFSKVKGDKYNPMLTVVVVSKRINTKYFSLDSKGLSNPCPGSVLDHTVTRPNWPDYFLVSQHVRQGTVSPTHYIVVSGHEHLKPDHMQRLSYKLTHMYYNWPGTVRVPAPCQYAHKLAYLVGQSLGQHPAPQLCNKLFYL"
     misc_feature    992..1141
                     /gene="LOC100181639"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    1103..1501
                     /gene="LOC100181639"
                     /note="PAZ domain, Piwi_like subfamily. In multi-cellular
                     organisms, the Piwi protein appears to be essential for
                     the maintenance of germline stem cells. In the Drosophila
                     male germline, Piwi was shown to be involved in the
                     silencing of retrotransposons in the...; Region:
                     PAZ_piwi_like; cd02845"
                     /db_xref="CDD:239211"
     misc_feature    order(1271..1273,1310..1312,1334..1336,1346..1348,
                     1400..1402,1460..1462,1466..1468)
                     /gene="LOC100181639"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239211"
     misc_feature    1523..2878
                     /gene="LOC100181639"
                     /note="PIWI domain, Piwi-like subfamily found in
                     eukaryotes. This domain is found in Piwi and closely
                     related proteins, where it is believed to perform a
                     crucial role in germline cells, via RNA silencing. RNA
                     silencing refers to a group of related...; Region:
                     Piwi_piwi-like_Euk; cd04658"
                     /db_xref="CDD:240016"
     misc_feature    order(2027..2029,2039..2041,2075..2086,2093..2095,
                     2132..2134,2141..2143,2153..2155,2165..2167)
                     /gene="LOC100181639"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240016"
     misc_feature    order(2228..2230,2234..2236,2438..2440,2852..2854)
                     /gene="LOC100181639"
                     /note="active site"
                     /db_xref="CDD:240016"
ORIGIN      
caagttgtttgcctttaattatagataccttgaatgttaatgaatgtcgaaaactaatgtattttgtgccgttaaattaatgcaactaagtctttgaacgtactttctgcgaattcgtttgtataagatggataagtttaacttaccaagcgttggaagaggccgcgggctttcagttttaaaattacttcaagaaaaatctgattctgaagctaaatctgaagaatgtggttccaccaccacacttgctgcaggggataacacaggggttgattctgccgtgtcaaaactaagtctgacaagctcactaggccgaggtcaaactgttgggttgataggtcgtgggcaagctttgtcgcccccatttcaactgcaaggtgctgctggtcgtggacaaatgtcatttttgtcaaaaggacgaggctctgctttacttcaggagcttggtattggtaaatcagcagaagctctaaaaccttgtgaaagtctgcccgttgtattgagagaaaagacaccagaagttgaacttaaaaagcagaaaactttaaccactcaaccacaatcaattgctcaaccatcaataacatcacaggatatcactaaggtggatgaggttgttaaataccatggtcaaagtggtcgacgaaacgatatacgagttaactgtgttcgtgtgaaatgcattaaccttgctgtatatcaataccatgtctcctttgaaccagtggttgacagcagaaacatgaggtttatgttgttaaaccagcatcgagaagttataggaaacacaaaagcctttgacgggaccatcctctatttaccaatgaagcttgagcttaatgaacttcgtctgaaatctaagcgtgtcacagatgaagcagatatcgttgtgttgatcaggttcacaaaagcaattgatcctgcctcttcccagctgatacctttttataacacagtattgaaacggtgtatgagactccttgatatgtgccccgttggccgaaactattatgaccctacatctccaaaaaccattgaaaagctgcaactgattttgtggcctgggtatgtcactgctatcaagaaatttgaggatggtttgatgttaaatattgatgtatcgcataaggttctgcgtcaggatacggccaaacatgtaatggttgaagcctacaaaagatccccaaaccaatatcgtgatgcttgtgtaaaggagttagttggagcgattgtgcttacgcggtacaacaataaaaactaccgtgttgatgatatagcgtgggacatgacaccctcaagctcttttaccaattcaaaaggtgacaagctcacttttgttgaatactacaaagttcaatacaaaatagaaatcactgacttgaagcaaccaatgttggtacatcgacctaaaaagcaaacgcagcgagatttcaagagaaatgaaggggaagattattgcatttgtttggtccctgagttgtgctaccttactggattatccgataagctgagatctgatttccgagcgatgcgagagatacgtgacaacacatcctttgatccaacccgacgaaatgcttgtctggaggagtttcttaagcgagttaacatgaacaccaatgcaaagaacgaactactcagatggggtcttgaactcgacatgaaaacttgctccactttttctcgctctcttccttctgaaaagatcatggtaggaagaaaccaagtgttctcatgcggtccagatgcagattttggaagagaagttacgcgctcacctgttattactccaatcccaattaataactggctacttgttttcgtaaagagagattcgaacaaggctgaaaatttctttcaaaagatgatggaatgtacaagaaagttggggattgatctcagcaagcccagatttcttcaattgaatgatgacagaacaacaagctataaagatgccatctctcaatcactgaacccatccacacagctggtggtgtgtatattccctacttcccgtgatgatagatacaacgccataaagaaattatgctgcgtcgacatgcctgtcccttcgcaagtcatcatttcacgcactttacccgatgacgcaaaaatgggaaagtttcggtcagtgacaatgaaaattgctcttcagatcaactgtaagcttggtggggaactctggacagttgacatccctcttaaaggacttatggtttgtgggattgacgtttatcatgatccattaaaaagaggaaaatctgttgcagcatttattgcaagttctaacaggttaatgtctacttggttttcaaaagcaatcattcaacaacctcaccaagagttaatcgatagtttgaaacagtgctttgtaaatgcattgaagaattactatgagctaaatcatgctttgccagagcgtatcgttattttccgagatggagtcggtgatggtcaactaaacatagtggctgaacacgaagtggttcaacttcaatcatgttttgaaatgttctcaaaggttaagggggataaatataacccaatgctaacagttgtggtagtttctaaacgcatcaacacaaagtatttttcacttgattcgaaaggtttgtctaatccctgcccaggctctgtgttagatcatactgtgacacgaccaaactggccggattacttcttggtgtctcagcacgtaagacagggtaccgtctcacctacacattacattgtagtcagtggtcatgaacatttaaaacccgatcacatgcaacgtctgtcatataaactcacacacatgtactacaactggccaggaaccgtaagagtgcccgcaccttgccaatatgctcataaacttgcttaccttgttggtcaaagccttgggcagcaccctgcaccgcaactttgtaacaagctgttttatttataattgtgtagccggtatattaaaatgtgttaccgatttttgatggtttgcctgtatttgctttctatgccagcaaattttgtgtaagttatccaaaacaaggcgtgccaaattattgaatataagcttcagccatttaaaaaactgttatttggagttcaaattttacctgcttcaagtttttttaactgccgagtaactacacacacaccatatttaatatgcattgttttataattttaatacatcgtgctttttcaacatttttatctcaatgtcttctacaatttgcttaatgtttaattcaatagtatcattcagtacaaagtcaacaattcaaaacataaccaacatttttcatcaaatgtaaatgagacatgctgttaaatatatgggaactttatttaataatgtggtcgaatgcaacagtataactggacactaaaacataatgtcactgctgtaactttgttgactttcaattgtctgaacacaaaccgttccattttctatttctttgttcgttctttatatttcacagattgcatgttcgcagcatttataatttaaaatatcatttggacgattttgcaataatttttttataggtaaaattgccaatcctaattttatgtcaccaaatttctttattgcagaagagtttctcaattaacgctatgtttatataatatttcaaaatctgtcaccttgaaaatacaaaaacaagcaagatctttttaaagttatttggtaatttacgctggttatgctaaaaccggtaccaagacaatggctgccgtgttcaatgagttcggctacaatacgtacgacttctttgagaactcgttttacctcggtaaggattgggtaaaaataatcaacgaaggtggaaccgtggaagattttcgaagaatgtacaaaggtgttgattcgccaacttttattttctgggaggaaatatcagaagcttacccggaagctaagataatcttttctgtgcgggatgaagaatcctggcttcgtagtttggagaagcaagtacattctcatgtgtctgaaccgaagtatcttttaatgcaaatgctctcttactcaggatggggcctctttaggtttactcaagctactgctcttgtggttatcggtgccgcaataaagtggccttggggaccagtaaattataacccaacattatggaagagaatttataggaatcacaacagcaacgttctgcaaaacgcaccaaaagataaactgttgatagtcaactttaaagacggttggggaccaatctgtgaattcctgggggagaaagttccagacaagcccttcccgcatgcgaacaagggagcatcgcttataaaggaatcgatggaaagtcacccgatcgtgataaaaatgctcagagagacaatgtttactctcggagttcttactctcattggggcgtatggtgggtacaaggtttaccaaaacccagcaagtataagtggttggttcaataatacgatgataaggtttaagttctggtaactcgtaatcctaattttaaaagcagagtctctaggttacagtgttataattttttgaaagttctttgtttactaccaaacgggacgagaaaatagaacgaaaaggtgtcccatcttccccactctactatataaaactccaatacattaacatctgccagctttactagtattgtgcttgtcaggaacttgagagctcaagtgtgtctgcataagttggtaattcaaagttcgtagatgtattgtttgcattaattgtctagctctttctacgaagttagatttgtttacatgtagaaatcataaaggccttgtaggcctatactgcttactgtttgtcattgtcaacttattgttcgccagtgctgtaaaataaaactgctatgggctataacgta
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]