LOCUS       NM_062750               2739 bp    mRNA    linear   INV 22-NOV-2023
DEFINITION  Caenorhabditis elegans Piwi-like protein (wago-5), partial mRNA.
ACCESSION   NM_062750
VERSION     NM_062750.3
DBLINK      BioProject: PRJNA158
KEYWORDS    RefSeq.
SOURCE      Caenorhabditis elegans
  ORGANISM  Caenorhabditis elegans
            Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
            Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
            Caenorhabditis.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Sulson,J.E. and Waterston,R.
  CONSRTM   Caenorhabditis elegans Sequencing Consortium
  TITLE     Genome sequence of the nematode C. elegans: a platform for
            investigating biology
  JOURNAL   Science 282 (5396), 2012-2018 (1998)
   PUBMED   9851916
  REMARK    Erratum:[Science 1999 Jan 1;283(5398):35]
REFERENCE   2  (bases 1 to 2739)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (22-NOV-2023) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 2739)
  AUTHORS   WormBase.
  CONSRTM   WormBase Consortium
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2023) WormBase Group, European Bioinformatics
            Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org
REFERENCE   4  (bases 1 to 2739)
  AUTHORS   Sulson,J.E. and Waterston,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAR-2003) Nematode Sequencing Project: Sanger
            Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute
            at Washington University, St. Louis, MO 63110, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by WormBase. This
            record is derived from an annotated genomic sequence (NC_003280).
            
            On Feb 27, 2013 this sequence version replaced NM_062750.2.
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..2739
                     /organism="Caenorhabditis elegans"
                     /mol_type="mRNA"
                     /strain="Bristol N2"
                     /db_xref="taxon:6239"
                     /chromosome="II"
     gene            <1..>2739
                     /gene="wago-5"
                     /locus_tag="CELE_ZK1248.7"
                     /db_xref="GeneID:191545"
                     /db_xref="WormBase:WBGene00022877"
     CDS             1..2739
                     /gene="wago-5"
                     /locus_tag="CELE_ZK1248.7"
                     /standard_name="ZK1248.7"
                     /note="Partially confirmed by transcript evidence"
                     /codon_start=1
                     /product="Piwi-like protein"
                     /protein_id="NP_495151.3"
                     /db_xref="EnsemblGenomes-Gn:WBGene00022877"
                     /db_xref="EnsemblGenomes-Tr:ZK1248.7"
                     /db_xref="GeneID:191545"
                     /db_xref="GOA:D9N120"
                     /db_xref="InterPro:IPR003100"
                     /db_xref="InterPro:IPR003165"
                     /db_xref="InterPro:IPR012337"
                     /db_xref="InterPro:IPR036085"
                     /db_xref="InterPro:IPR036397"
                     /db_xref="UniProtKB/TrEMBL:D9N120"
                     /db_xref="WormBase:WBGene00022877"
                     /translation="

MNTGVVLLDQNDQKLYQTTANDACINRLKELNVESGAKIYTTPTEPGTLGKQVDVGTNIFGVEVTKETTVHRFVVHAKADLTSTKEVTFTKKGKEDFVVLDRREKCCNLFFNAVEKNPDFFKMKDGNHIVYDGQSTLYTTINLFSELDCNQTKSKVFQINGADTGNDELKTLPCISLEIHAPRDNSITISAKILGERTADQNIEVNNREYTQFLELALNQHCTRETKRFGCFEHGKVYFLNATEEGFDQRDCVDVGDGKALYPGLKKTIQFIEGPFGRGQNNPSLVIDGMKAAFHKEQTVIQKLFEITGQDPSNGLSSMAREKATPVIKGLDCYSMYTSRKRHLRIVGIFHESATGTRFELPDGKTCSIAEYFRDKYSINLQYPKANLVVCKDRGNNNYFPAELMTISKNQRATIPQQTQSQKTTKECAVLPDVRQRIIIKGKTAVNITAENELLNALGIKVYSEPLKVSLKELGYQRSTVKSELGKWRPPPGSFVKPAAFQDLWALYAVGNQNSRFSVSDLSQFTGMFIDACKKRGMIIKPPSETSLCHMDNIISLLENAAASKCKFAFVITDDSITHLHKKYKALEQKSMMVIQDMKISKANSVVKDGKRLTLENVINKTNMKLGGLNYTVSDAKKSMTDEQLIIGVGVSAPPAGTKYMMDNKGHLNPQIIGFASNAVANHEFVGDFVLAPSGQDTMASIEDVLKSSIDLFEMNRNTLPKRIIIYRSGASDGSHASILAYEIPLARATIQGYSKDINLIYIIVTKEHSYRFFRDQLRSGGKATEMNIPPGIVLDSAVTNPACKQFFLNGHTTLQGTAKTPLYTILADDCNAPMDRLEELTYTLCHHHQIVALSTSIPTPLYVANEYAKRGRDLWAHGPNEANEYHEEHLKELSKQLGYKNTVFNKTRINA"

     misc_feature    889..1221
                     /gene="wago-5"
                     /locus_tag="CELE_ZK1248.7"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1030..1032,1075..1077,1105..1107,1117..1119,
                     1171..1173,1192..1194,1198..1200)
                     /gene="wago-5"
                     /locus_tag="CELE_ZK1248.7"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1702..2628
                     /gene="wago-5"
                     /locus_tag="CELE_ZK1248.7"
                     /note="This domain is found in the protein Piwi and its
                     relatives; Region: Piwi; smart00950"
                     /db_xref="CDD:214930"
     misc_feature    order(1741..1743,1753..1755,1786..1797,1804..1806,
                     1840..1842,1849..1851,1861..1863,1873..1875)
                     /gene="wago-5"
                     /locus_tag="CELE_ZK1248.7"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:239208"
     misc_feature    order(1948..1950,1954..1956,2185..2187,2596..2598)
                     /gene="wago-5"
                     /locus_tag="CELE_ZK1248.7"
                     /note="active site"
                     /db_xref="CDD:239208"
ORIGIN      

atgaatactggcgttgtcctgttggatcaaaatgatcaaaagctctaccaaacgactgccaatgatgcatgcatcaatcgtctgaaagaattgaacgtggaaagtggagctaagatctacactacgccaaccgaaccgggaacattgggtaaacaagtggatgttggaacaaacatcttcggagtggaagttaccaaggaaacaacagttcacagattcgtggttcatgccaaggccgatttgacttccacgaaggaagtgaccttcactaaaaaaggaaaagaggacttcgtagtgttggatcgtcgtgagaaatgctgcaacctgtttttcaatgcagtggagaagaacccagatttcttcaaaatgaaagacgggaatcatatcgtatatgacggccaatccactctctacactacgatcaatttgttctcggaactggattgcaaccagacaaagtctaaagtctttcaaatcaatggagcggacacgggaaacgacgaactcaagacgttgccgtgcatctctcttgagattcatgcaccacgagacaattccatcaccatctctgctaaaatcctgggcgagcgtactgctgatcaaaacattgaagtgaacaatcgtgaatacactcaattcctggaacttgctttgaatcaacattgcacgagggaaacaaagcgtttcggatgtttcgagcatggaaaagtatatttcctcaacgccaccgaggaaggatttgatcagcgagattgtgtcgacgttggcgacggaaaagcgctgtatcctggcctcaagaagacgatccaattcattgaaggtccgttcggtcgtggacagaacaatccatctcttgtgattgatggcatgaaagctgctttccataaagagcaaactgtgatccagaagctctttgagattacgggacaagatccatcaaacgggctcagtagtatggctcgtgagaaggctactccagtgattaaaggactcgattgctattcaatgtacacgagcagaaagcgtcatctgagaatcgtaggaatcttccacgaaagtgccacagggacgagattcgagttgcccgatgggaagacgtgttcaatcgccgagtacttcagggacaaatacagcataaatcttcaatacccgaaagccaatttggtggtttgcaaagatcgaggaaacaacaattacttcccggctgaattgatgaccatctcgaaaaatcagcgtgcaactattcctcagcaaactcagtctcagaagacgacgaaggaatgtgcggttctccctgatgttcgccagagaatcatcatcaagggcaaaactgctgtcaacatcacagcggagaatgagctcctcaacgctcttggaatcaaagtttattcagagcctttgaaggttagtttgaaagaactgggataccagagatcaacggtcaagtctgagttgggaaaatggcgtccaccaccagggtcatttgtgaaacccgctgcttttcaagatttatgggctttgtatgctgttggaaatcaaaattccagattctccgttagtgacctgagccaattcaccggaatgttcattgatgcttgcaagaagagaggaatgataatcaagcctccaagtgaaacatccctttgtcacatggataacataatttccctactggaaaatgcggctgcgagcaaatgcaaatttgccttcgtgatcaccgatgactctatcactcatctccacaagaaatacaaggccctcgaacaaaagtcgatgatggttatacaggatatgaaaatttccaaagccaactctgttgtcaaggatggaaagagattgactctggaaaacgtcatcaacaaaactaacatgaagttgggtggtctcaactacacggtctcggatgcaaagaagagcatgaccgacgaacaattgatcatcggagttggcgtttccgcaccaccggctggaacgaagtacatgatggataacaaaggacatcttaatccacaaattattggcttcgcttcaaatgctgttgcaaaccacgagtttgttggagatttcgttttggccccttcaggacaggatacaatggcatcaattgaagacgttttgaaaagttccatcgatctgtttgagatgaatcgcaatactttgccaaagcggatcatcatttatagaagtggtgcatcggatggctctcatgcgtctattcttgcctacgaaattccactggcacgtgctaccattcagggatactccaaagatatcaatctgatttacatcatcgtcaccaaggagcacagttacagatttttccgtgatcagcttcgttccggcggaaaagcgacagagatgaacatcccaccgggtatcgtcttggatagcgctgtcaccaatcctgcatgcaagcaattcttcctcaatggacacacaactctgcaaggaactgccaagactcctctctacactattctggcagatgactgtaacgctccgatggatcgccttgaggagctcacatacactctttgccatcaccatcaaatcgtggcactgagcacttcaattccgactcctctttatgttgccaacgagtatgcaaaacgtggaagagatctctgggctcatggacctaatgaagcgaatgaataccatgaagagcatctcaaggaactttcaaaacaactcggatacaagaacactgtcttcaacaagactcgcatcaatgcttag

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