LOCUS       NM_127193               3104 bp    mRNA    linear   PLN 20-OCT-2022
DEFINITION  Arabidopsis thaliana SNF2 domain-containing protein / helicase
            domain-containing protein (DRD1), mRNA.
ACCESSION   NM_127193
VERSION     NM_127193.2
DBLINK      BioProject: PRJNA116
            BioSample: SAMN03081427
KEYWORDS    RefSeq.
SOURCE      Arabidopsis thaliana (thale cress)
  ORGANISM  Arabidopsis thaliana
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
            Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
            Camelineae; Arabidopsis.
REFERENCE   1  (bases 1 to 3104)
  AUTHORS   Lin,X., Kaul,S., Rounsley,S., Shea,T.P., Benito,M.I., Town,C.D.,
            Fujii,C.Y., Mason,T., Bowman,C.L., Barnstead,M., Feldblyum,T.V.,
            Buell,C.R., Ketchum,K.A., Lee,J., Ronning,C.M., Koo,H.L.,
            Moffat,K.S., Cronin,L.A., Shen,M., Pai,G., Van Aken,S., Umayam,L.,
            Tallon,L.J., Gill,J.E., Adams,M.D., Carrera,A.J., Creasy,T.H.,
            Goodman,H.M., Somerville,C.R., Copenhaver,G.P., Preuss,D.,
            Nierman,W.C., White,O., Eisen,J.A., Salzberg,S.L., Fraser,C.M. and
            Venter,J.C.
  TITLE     Sequence and analysis of chromosome 2 of the plant Arabidopsis
            thaliana
  JOURNAL   Nature 402 (6763), 761-768 (1999)
   PUBMED   10617197
REFERENCE   2  (bases 1 to 3104)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 3104)
  AUTHORS   Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
            Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
            Vaughn,M. and Town,C.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
            9704 Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Protein update by submitter
REFERENCE   4  (bases 1 to 3104)
  AUTHORS   Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
  CONSRTM   TAIR
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
            Institution, 260 Panama Street, Stanford, CA, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by TAIR and Araport.
            This record is derived from an annotated genomic sequence
            (NC_003071).
            
            On May 26, 2011 this sequence version replaced NM_127193.1.
FEATURES             Location/Qualifiers
     source          1..3104
                     /organism="Arabidopsis thaliana"
                     /mol_type="mRNA"
                     /db_xref="taxon:3702"
                     /chromosome="2"
                     /ecotype="Columbia"
     gene            1..3104
                     /gene="DRD1"
                     /locus_tag="AT2G16390"
                     /gene_synonym="CHR35; DEFECTIVE IN MERISTEM SILENCING 1;
                     DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1; DMS1;
                     F16F14.11; F16F14_11"
                     /note="Putative chromatin remodeling protein, member of a
                     plant-specific subfamily of SWI2/SNF2-like proteins.
                     Mutations nearly eliminate non-CpG methylation at a target
                     promoter but do not affect rDNA or centromere methylation.
                     Cooperates with PolIVb to facilitate RNA-directed de novo
                     methylation and silencing of homologous DNA. Endogenous
                     targets include intergenic regions near retrotransposon
                     LTRs or short RNA encoding sequences that might
                     epigenetically regulate adjacent genes. May be used to
                     establish a basal yet reversible level of silencing in
                     euchromatin."
                     /db_xref="Araport:AT2G16390"
                     /db_xref="GeneID:816136"
                     /db_xref="TAIR:AT2G16390"
     CDS             359..3025
                     /gene="DRD1"
                     /locus_tag="AT2G16390"
                     /gene_synonym="CHR35; DEFECTIVE IN MERISTEM SILENCING 1;
                     DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1; DMS1;
                     F16F14.11; F16F14_11"
                     /inference="Similar to RNA sequence,
                     EST:INSD:ES083184.1,INSD:ES034363.1,INSD:EL098697.1,
                     INSD:BE525817.1,INSD:CB518291.1,INSD:ES038960.1"
                     /note="DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1 (DRD1);
                     FUNCTIONS IN: helicase activity, DNA binding, ATP binding,
                     nucleic acid binding; INVOLVED IN: DNA methylation,
                     production of siRNA involved in RNA interference; LOCATED
                     IN: cellular_component unknown; EXPRESSED IN: 9 plant
                     structures; EXPRESSED DURING: 6 growth stages; CONTAINS
                     InterPro DOMAIN/s: DEAD-like helicase, N-terminal
                     (InterPro:IPR014001), DNA/RNA helicase, C-terminal
                     (InterPro:IPR001650), Helicase, superfamily 1/2,
                     ATP-binding domain (InterPro:IPR014021), SNF2-related
                     (InterPro:IPR000330); BEST Arabidopsis thaliana protein
                     match is: chromatin remodeling 34 (TAIR:AT2G21450.1); Has
                     13448 Blast hits to 11886 proteins in 1506 species: Archae
                     - 91; Bacteria - 3564; Metazoa - 3285; Fungi - 3284;
                     Plants - 1229; Viruses - 105; Other Eukaryotes - 1890
                     (source: NCBI BLink)."
                     /codon_start=1
                     /product="SNF2 domain-containing protein / helicase
                     domain-containing protein"
                     /protein_id="NP_179232.1"
                     /db_xref="Araport:AT2G16390"
                     /db_xref="GeneID:816136"
                     /db_xref="TAIR:AT2G16390"
                     /translation="

MGFVYIVMTGYYKNVHKRKQNQVDDGPEAKRVKSSAKVIDYSNPFAVSNMLEALDSGKFGSVSKELEEIADMRMDLVKRSIWLYPSLAYTVFEAEKTMDNQQVVEGVINLDDDDDDDTDVEKKALCVVPSSSEIVLLDSDDEDNERQRPMYQFQSTLVQHQKNQGDVTPLIPQCSFEEVDLGRGKEMPSAIKAIVEGQTSRGKVLPIENGVVNEKGVYVGVEEDDSDNESEAADEDLGNIWNEMALSIECSKDVARETSHKEKADVVEDCEHSFILKDDMGYVCRVCGVIEKSILEIIDVQFTKAKRNTRTYASETRTKRFGESDNELKFSEEGLMIGGLAAHPTHAAEMKPHQIEGFQFLCSNLVADDPGGCIMAHAPGSGKTFMIISFMQSFLAKYPQAKPLVVLPKGILPTWKKEFVRWQVEDIPLLDFYSAKAENRAQQLSILKQWMEKKSILFLGYQQFSTIVCDDTTDSLSCQEILLKVPSILILDEGHTPRNEDTNLLQSLAQVQTPRKVVLSGTLYQNHVKEVFNILNLVRPKFLKLDTSKSAVKRILAYTPCDVRGRLTGSNSDMASMFNETVEHTLQKSEDFTVKIKVIQDLREMTKKVLHYYKGDFLDELPGLADFTVVLNLSPKQLNEVKKLRREKRKFKVSAVGSAIYLHPKLKVFSDKSDDVSDTTMDEMVEKLDLNEGVKAKFFLNLINLCDSAGEKLLVFSQYLIPLKFLERLAALAKGWKLGKEVFVLTGNTSSEQREWSMETFNSSPDAKIFFGSIKACGEGISLVGASRILILDVPLNPSVTRQAIGRAFRPGQKKMVHAYRLIAGSSPEEEDHNTCFKKEVISKMWFEWNEYCGYQNFEVETIDVDEAGDTFLESPALREDIRVLYKR"

     misc_feature    1406..2056
                     /gene="DRD1"
                     /locus_tag="AT2G16390"
                     /gene_synonym="CHR35; DEFECTIVE IN MERISTEM SILENCING 1;
                     DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1; DMS1;
                     F16F14.11; F16F14_11"
                     /note="DEXH-box helicase domain of ATRX-like proteins;
                     Region: DEXHc_ATRX-like; cd18007"
                     /db_xref="CDD:350765"
     misc_feature    order(1493..1513,1610..1612,1832..1837)
                     /gene="DRD1"
                     /locus_tag="AT2G16390"
                     /gene_synonym="CHR35; DEFECTIVE IN MERISTEM SILENCING 1;
                     DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1; DMS1;
                     F16F14.11; F16F14_11"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350765"
     misc_feature    2414..2827
                     /gene="DRD1"
                     /locus_tag="AT2G16390"
                     /gene_synonym="CHR35; DEFECTIVE IN MERISTEM SILENCING 1;
                     DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1; DMS1;
                     F16F14.11; F16F14_11"
                     /note="C-terminal helicase domain of the SNF family
                     helicases; Region: SF2_C_SNF; cd18793"
                     /db_xref="CDD:350180"
     misc_feature    order(2513..2518,2540..2542,2681..2683,2744..2749)
                     /gene="DRD1"
                     /locus_tag="AT2G16390"
                     /gene_synonym="CHR35; DEFECTIVE IN MERISTEM SILENCING 1;
                     DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1; DMS1;
                     F16F14.11; F16F14_11"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:350180"
     misc_feature    order(2699..2704,2708..2710,2777..2779,2786..2788)
                     /gene="DRD1"
                     /locus_tag="AT2G16390"
                     /gene_synonym="CHR35; DEFECTIVE IN MERISTEM SILENCING 1;
                     DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1; DMS1;
                     F16F14.11; F16F14_11"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350180"
ORIGIN      

tcaaattcccgagtcagagtctctcagcttcgaagcacgagcgagcgaggcaaaccaaaaagaatccaatttacatcatcttctccaaaattcagctcgaaattttcaacctttactggtttaatggacattctccagaccgatcaagcttcctcaaacggtatacgaatctctctgtgaaaaaaattaggtctttcttctgattttagtgtcactacattatatgcatgtcgttcccaaacccgattttgtgttagttgatccaaatatttgaagaaattatgagtaattttgcaatgttctgaagccaaagttgttgtctttcttgtttttgtttatttggagagtaatgtgacagatgggttttgtttacattgtgatgacagggtactataagaatgtgcataaaagaaagcaaaatcaagttgatgatggacctgaagcaaagcgggtcaagagttcagccaaagttattgattactctaacccatttgcagttagtaacatgcttgaagctttagatagtggtaaatttgggagtgttagtaaagagttggaagagatagctgatatgaggatggatttggttaagcgttctatttggttatacccgtcgctagcgtataccgtgtttgaagctgagaagacgatggataatcaacaggttgtggaaggtgttattaatttggatgatgatgatgatgatgatactgatgtggagaagaaagctctctgtgttgttccttcgtcgtctgagattgtgcttcttgattctgatgatgaagacaatgagaggcagaggcctatgtatcagtttcagtctactcttgtacagcatcagaagaatcaaggggatgtgactccattaataccgcaatgctctttcgaggaggtcgatttagggaggggcaaggagatgccttctgccattaaagccattgttgagggacaaacaagtagaggcaaagtccttcctatagaaaatggtgtggttaatgagaaaggtgtctacgtgggcgttgaggaggatgacagtgataatgagtctgaagcagcagatgaagatcttggtaatatctggaatgaaatggccttgtcaatagagtgttccaaggatgtagcaagggagacttcacataaggaaaaggcagatgtagtggaagattgtgagcactcatttattctaaaggacgatatgggttatgtttgccgtgtctgcggagttattgagaaaagtatactagagataattgatgtgcaattcactaaagcaaaacgaaacacaagaacatatgcctctgaaactagaactaaaaggtttggcgaatctgataatgaacttaagttttctgaagaagggttgatgataggtggacttgctgctcatccaacgcatgctgccgaaatgaagcctcatcaaattgagggatttcagttcctttgcagcaatttagtggctgacgatcctggtggctgtatcatggctcatgctccaggctctggaaaaaccttcatgatcatcagttttatgcagagctttcttgcaaagtatcctcaggctaagccattggttgttctcccaaaaggtattctgcctacttggaaaaaagagttcgtgagatggcaagttgaggacataccactgcttgatttctatagtgctaaagcagagaaccgggcacagcagctgtctattttgaaacagtggatggagaagaagagtatcttatttcttgggtaccagcagttctcaactattgtgtgtgatgatacaaccgactcactttcttgccaggagatactgctcaaggtaccttcgatcctcattttggatgaaggacacactccaaggaatgaggacacaaatttattgcagtcacttgcccaagtccaaacaccaagaaaagttgtcctctcaggaacgctttatcagaaccatgtaaaggaggttttcaacattctgaaccttgttcgacccaaattcctcaaattggatacctccaaatctgctgtgaagagaatcttggcttatactccatgcgatgtcagggggagacttactggaagtaattcagatatggcttcaatgttcaatgaaactgtggagcacaccctgcagaagagcgaggatttcacagtgaaaattaaagtaatccaagatttgcgggagatgacaaagaaagtgcttcattactataaaggagatttcctagatgagcttcctggacttgctgatttcactgtggttcttaatctgtctccaaagcagttgaacgaagtgaagaagttaagacgtgagaagagaaaatttaaggtttcggctgtgggaagtgcaatttaccttcacccgaagctgaaagttttctctgacaagtctgatgatgtttctgatacaactatggacgaaatggtagagaagctagatttgaatgaaggcgtcaaagcaaagttcttccttaacttgataaacctgtgcgactcagctggtgaaaagctcttggttttcagccagtatctcattccactaaagtttcttgaaagactagctgctttagctaagggatggaaactagggaaagaagtttttgttcttacaggcaataccagttctgagcagcgtgagtggtcaatggaaacgtttaacagttcgccagacgccaaaatattctttggttcgataaaagcatgtggagaaggtatctcgcttgttggagcatctcgcatactaatattggatgttcccctaaacccttctgtgacccgccaagctattgggcgagcgtttcgacccggacaaaagaagatggtgcatgcatatagattgattgctgggtcatcacctgaggaagaggatcacaacacttgtttcaaaaaggaagtcatctcaaagatgtggttcgagtggaacgagtactgcggatatcaaaactttgaggtagagacgatcgatgtggatgaagctggtgatacgttcctcgaaagtcctgccttaagagaagacataagagttctctacaaaaggtaaacgcagacagaaacttgtgcttccgctttttggacatgcttaggttttagaaacctgtcaataagataacttcgggtag

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