LOCUS       NM_101702               1721 bp    mRNA    linear   PLN 20-OCT-2022
DEFINITION  Arabidopsis thaliana actin-related protein 4 (ARP4), mRNA.
ACCESSION   NM_101702
VERSION     NM_101702.4
DBLINK      BioProject: PRJNA116
            BioSample: SAMN03081427
KEYWORDS    RefSeq.
SOURCE      Arabidopsis thaliana (thale cress)
  ORGANISM  Arabidopsis thaliana
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
            Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
            Camelineae; Arabidopsis.
REFERENCE   1  (bases 1 to 1721)
  AUTHORS   Theologis,A., Ecker,J.R., Palm,C.J., Federspiel,N.A., Kaul,S.,
            White,O., Alonso,J., Altafi,H., Araujo,R., Bowman,C.L.,
            Brooks,S.Y., Buehler,E., Chan,A., Chao,Q., Chen,H., Cheuk,R.F.,
            Chin,C.W., Chung,M.K., Conn,L., Conway,A.B., Conway,A.R.,
            Creasy,T.H., Dewar,K., Dunn,P., Etgu,P., Feldblyum,T.V., Feng,J.,
            Fong,B., Fujii,C.Y., Gill,J.E., Goldsmith,A.D., Haas,B.,
            Hansen,N.F., Hughes,B., Huizar,L., Hunter,J.L., Jenkins,J.,
            Johnson-Hopson,C., Khan,S., Khaykin,E., Kim,C.J., Koo,H.L.,
            Kremenetskaia,I., Kurtz,D.B., Kwan,A., Lam,B., Langin-Hooper,S.,
            Lee,A., Lee,J.M., Lenz,C.A., Li,J.H., Li,Y., Lin,X., Liu,S.X.,
            Liu,Z.A., Luros,J.S., Maiti,R., Marziali,A., Militscher,J.,
            Miranda,M., Nguyen,M., Nierman,W.C., Osborne,B.I., Pai,G.,
            Peterson,J., Pham,P.K., Rizzo,M., Rooney,T., Rowley,D., Sakano,H.,
            Salzberg,S.L., Schwartz,J.R., Shinn,P., Southwick,A.M., Sun,H.,
            Tallon,L.J., Tambunga,G., Toriumi,M.J., Town,C.D., Utterback,T.,
            Van Aken,S., Vaysberg,M., Vysotskaia,V.S., Walker,M., Wu,D., Yu,G.,
            Fraser,C.M., Venter,J.C. and Davis,R.W.
  TITLE     Sequence and analysis of chromosome 1 of the plant Arabidopsis
            thaliana
  JOURNAL   Nature 408 (6814), 816-820 (2000)
   PUBMED   11130712
REFERENCE   2  (bases 1 to 1721)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 1721)
  AUTHORS   Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
            Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
            Vaughn,M. and Town,C.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JUL-2017) Plant Genomics, J. Craig Venter Institute,
            9704 Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Protein update by submitter
REFERENCE   4  (bases 1 to 1721)
  AUTHORS   Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
            Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
            Vaughn,M. and Town,C.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
            9704 Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Protein update by submitter
REFERENCE   5  (bases 1 to 1721)
  AUTHORS   Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
  CONSRTM   TAIR
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
            Institution, 260 Panama Street, Stanford, CA, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by TAIR and Araport.
            This record is derived from an annotated genomic sequence
            (NC_003070).
            
            On Sep 12, 2016 this sequence version replaced NM_101702.3.
FEATURES             Location/Qualifiers
     source          1..1721
                     /organism="Arabidopsis thaliana"
                     /mol_type="mRNA"
                     /db_xref="taxon:3702"
                     /chromosome="1"
                     /ecotype="Columbia"
     gene            1..1721
                     /gene="ARP4"
                     /locus_tag="AT1G18450"
                     /gene_synonym="actin-related protein 4; ATARP4; F15H18.8;
                     F15H18_8"
                     /note="Encodes a gene similar to actin-related proteins in
                     other organisms. Member of nuclear ARP family of genes.
                     Component of chromatin remodeling complexes, involved in
                     chromatin-mediated gene regulation. Phenotype of the
                     arp4-1 mutant allele revealed partial sterility due to
                     defects in anther development. Targeting the distinct, 3'
                     UTR of AtARP4 transcripts with RNA interference caused a
                     drastic reduction in the level of AtARP4 protein
                     expression, and resulted in strong pleiotropic phenotypes
                     such as altered organization of plant organs, early
                     flowering, delayed flower senescence and high levels of
                     sterility. Western blot analysis and immunolabelling
                     demonstrated a clear correlation between reductions in the
                     level of AtARP4 expression and severity of the
                     phenotypes."
                     /db_xref="Araport:AT1G18450"
                     /db_xref="GeneID:838425"
                     /db_xref="TAIR:AT1G18450"
     CDS             152..1477
                     /gene="ARP4"
                     /locus_tag="AT1G18450"
                     /gene_synonym="actin-related protein 4; ATARP4; F15H18.8;
                     F15H18_8"
                     /inference="Similar to RNA sequence,
                     EST:INSD:AV535502.1,INSD:DR208240.1,INSD:AV555243.1,
                     INSD:BP568747.1,INSD:ES099247.1,INSD:ES094398.1,
                     INSD:EG521024.1,INSD:DR208238.1,INSD:BP848766.1,
                     INSD:AA720074.1,INSD:BX837525.1,INSD:ES212111.1,
                     INSD:ES126034.1,INSD:AV541926.1,INSD:AI992577.1,
                     INSD:BP845201.1,INSD:EL179472.1,INSD:AV521175.1,
                     INSD:ES123148.1,INSD:BU635035.1,INSD:EG521035.1,
                     INSD:AU226792.1,INSD:DR208236.1,INSD:BP858490.1,
                     INSD:BP816333.1,INSD:ES161463.1,INSD:DR208234.1,
                     INSD:EH934494.1,INSD:ES044129.1,INSD:ES168662.1,
                     INSD:EL985549.1,INSD:DR208239.1,INSD:EL028803.1,
                     INSD:AV566067.1,INSD:BP632803.1,INSD:ES214939.1,
                     INSD:BP621934.1,INSD:BP600229.1,INSD:BP628762.1,
                     INSD:BP576973.1,INSD:AV552990.1,INSD:ES053118.1,
                     INSD:BP622869.1,INSD:EL983462.1,INSD:BP844513.1,
                     INSD:AV553391.1,INSD:BP623609.1,INSD:BP852626.1,
                     INSD:BX836872.1,INSD:ES215021.1,INSD:EL977223.1,
                     INSD:AV527857.1,INSD:ES168950.1,INSD:BP800997.1,
                     INSD:ES073002.1,INSD:BP668421.1,INSD:BP866131.1,
                     INSD:BP567000.1,INSD:BP593018.1,INSD:DR208237.1,
                     INSD:BP848411.1,INSD:EL192166.1,INSD:AV531042.1"
                     /inference="similar to RNA sequence,
                     mRNA:INSD:AK228098.1,INSD:AY087788.1,INSD:BX814441.1"
                     /note="actin-related protein 4 (ARP4); FUNCTIONS IN:
                     structural constituent of cytoskeleton; INVOLVED IN:
                     long-day photoperiodism, flowering, chromatin
                     organization, pollen sperm cell differentiation; LOCATED
                     IN: nucleolus, nucleus; EXPRESSED IN: 25 plant structures;
                     EXPRESSED DURING: 14 growth stages; CONTAINS InterPro
                     DOMAIN/s: Actin/actin-like (InterPro:IPR004000); BEST
                     Arabidopsis thaliana protein match is: actin-11
                     (TAIR:AT3G12110.1); Has 13669 Blast hits to 13362 proteins
                     in 2792 species: Archae - 2; Bacteria - 480; Metazoa -
                     5593; Fungi - 3430; Plants - 1457; Viruses - 2; Other
                     Eukaryotes - 2705 (source: NCBI BLink)."
                     /codon_start=1
                     /product="actin-related protein 4"
                     /protein_id="NP_564051.1"
                     /db_xref="Araport:AT1G18450"
                     /db_xref="GeneID:838425"
                     /db_xref="TAIR:AT1G18450"
                     /translation="

MYGGDEVSAIVVDLGSHTCKAGYAGEDAPKAVFPSVIGAVDGVEAMDVDVDSTKTNSNSEDSKTESEKEKSKRKLYVGSQAMSYRRDHMEVLSPIKDGIVSDWDLVDNIWEHAFKSCLMIDPTEHPMLLAEPPLNTQQQREKAAELMFEKYKVPALFMAKNPVLTSFATGRATSLVVDCGGGSTTISPVHDGYVLQKAVVSSPLGGEFLTDCLLKSLESKGIKIRPRYSFKRKEVRAGEFQVEDVDIPDTTESYKLFCQRMIVGDIKDSICRVPDTPYDDKSYSNIPTTSYELPDGQTLEIGADRFKVPDVMFNPSIVQTIPGMEKYAEMIPSVRGLPHMVMESINKCDVDIRRELYSSILLAGGTSSMQQLKERLEKDLIEESPHSARVKVLASGNTTERRFSVWIGGSILASLGSFQQMWFSKSEYEEHGASYIQRKCP"

     misc_feature    170..1474
                     /gene="ARP4"
                     /locus_tag="AT1G18450"
                     /gene_synonym="actin-related protein 4; ATARP4; F15H18.8;
                     F15H18_8"
                     /note="Region: Actin; pfam00022"
                     /db_xref="CDD:394979"
ORIGIN      

gttttgtggtccccacaactcgaactcagtaaaaccaagtcgacccgattcagctggatccgagattacagagaaccccgtcccgtgtttaaaccctccggcgacaaagctcagatagagaaccgctccacccttgtcgttcgctgcagccatgtacggcggagatgaagtgtcagctattgtggttgacttgggttcgcacacttgcaaggctggttacgccggtgaagatgctcccaaggccgttttcccttccgttattggggcagtagatggtgtagaggcaatggatgtggatgttgattctacaaagactaattcgaactctgaggattcgaagaccgagtctgaaaaggaaaagagcaaacgcaagctctatgtaggatctcaagccatgagctaccgcagagatcatatggaggttttgtcacctataaaagatggcatcgtttctgactgggatttggtggacaatatatgggaacatgctttcaagagttgtctgatgattgatcctacggagcatccaatgctgctagctgagcctcctttaaacactcaacagcagagagagaaggcggcagagctaatgtttgaaaagtacaaagttccggcactgtttatggctaagaaccctgttctcacgtcttttgctactgggcgtgctacttctttggttgttgactgcggtggaggatccacaaccatttcaccggtgcatgatggttatgttcttcagaaggctgttgtatcgtctccacttggaggggaatttctcactgactgcctactgaaaagcttggagagtaaaggaattaaaataagacctagatactctttcaagaggaaggaagtacgagcaggggaattccaggttgaagatgtggatattcctgacaccacggaaagctacaaactcttctgccagaggatgatagtgggtgatatcaaggattccatttgtcgagttcctgatactccctatgacgataaatcatattcaaacatccctactacgtcgtacgagcttcctgatggccagacgctcgagattggtgctgataggttcaaagttcctgatgtgatgttcaacccgtccatagtccagacgattcctggaatggagaagtatgctgagatgattccttccgttcgtgggttaccacacatggtcatggagagcatcaacaaatgtgatgtagacatccggagagagttgtatagtagcatactgcttgctggtggcacatcgtcaatgcaacagctgaaagaacgtctcgaaaaggacttgatcgaagagtctcctcactcagctagagttaaagtgttggcaagcggtaacacaacagaaagaagattcagtgtatggataggagggagtatattggcatcactaggctcatttcaacagatgtggttctccaagtctgagtatgaggaacatggagcttcctacattcagagaaaatgcccttaaagcaggcagtttcagattatgtggagtctgacaagacgaaacttggaaactaatgtgttattttcattgtgcatcgttgttccttgaagattattagtattccgcctgaaccttttagaatgagtgtcattaacaagcattatagtgctattttaaaaacataaaaacatgtggaagaagtttcgttgctttattagattttcgcacaatcaagaccgtccacgttttgttactacgaaccaag

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