LOCUS       XM_067614194            4435 bp    mRNA    linear   VRT 22-AUG-2024
DEFINITION  PREDICTED: Thunnus thynnus NRDE-2, necessary for RNA interference,
            domain containing (nrde2), mRNA.
ACCESSION   XM_067614194
VERSION     XM_067614194.1
DBLINK      BioProject: PRJNA1130912
KEYWORDS    RefSeq.
SOURCE      Thunnus thynnus (Atlantic bluefin tuna)
  ORGANISM  Thunnus thynnus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Pelagiaria; Scombriformes; Scombridae; Thunnus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_089532) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963924715.1-RS_2024_07
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 07/03/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4435
                     /organism="Thunnus thynnus"
                     /mol_type="mRNA"
                     /db_xref="taxon:8237"
                     /chromosome="16"
     gene            1..4435
                     /gene="nrde2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 7 Proteins"
                     /db_xref="GeneID:137199711"
     CDS             46..3630
                     /gene="nrde2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2"
                     /protein_id="XP_067470295.1"
                     /db_xref="GeneID:137199711"
                     /translation="

MALFPAFADVSNDSKVEDSSKELEWLKNKSFQTGEALSLHNRFLEKTTERLSEKDSSVDRDEKESDVPPKKKKKKSEKHRKKKKKHKKKSGRYSDSSGSDSETIYPSDLKKEQEADRLQDAPLASRFSWLDDLKLPTEQPFCVDSKPDPANWTYKSLYRGDVARYKRKGRSSLGLDPRRQEVSWDESESNKKQKGGDKKKAADRYFSTVSRQLLRSQHPVPTLPTIPECSDVISPTSFLPLGDDEGENKGGETGDRVQTSSVNPLGVYDSSTTLWLQGKGQQDQTEHQKQDKQTGQSANLLAGRTEEFNRRLREQPADTQLWIQFIQYQDELSATAFGGEEEQQGTDSAERRKSSYRAVLEKKLSIAERAVATNPGCIALQLERLRICQELWEPSVLAKEWKKLVFLHPNSALFWREYLLFTQSYFSNFTVAKVNSAYGKCLSTLSAVRDGSMVSHPALPGIEEDMLDIFTQQCHFLRQCGHSEKAISLFQAMIDFTFYKPESVQKMSTKQQVEFFEPFWDSGEARVGELGARGWKAWMLQQERGGWLQPSAEEDEEEEEDEEEVKDRSQPRWTVWLDVESSREAAHWLPWRPDKAKGQSEEDCDDPDRQVLFDDIGSSLICLSSPELQLRLVLNFLSFLGLPVDSAAPCQLGLLLESLSLLTQGNDLQRPLTSHDLPGPGVNSVGHMTTLQGTRKLAGLGKHGERFVTNVFNMVQPVLPAHHRAVLSLSWMQYEKLKVLRCLRSGNKKRLRSQGKSSKRVAKRLLKEPDNRSSLMLWREYAHLEWMLGNLDEARKVFSTATAIGGTKGLSSPTLCELCLLWAQLEVEDGASVRGGGLSDVTASPAVCVLTRLAEGTSSSSSSSSQSLSPVSILKARKSYEQALTASLAALDQDPHNPQANRKGQEDLRGLVSCYALFQYLTVGIQAAHTVYSQARERMEELHRTLTFDKQLSSNEEANLASTDASHSAATSGPTSRQCVNRLASECEILAVQHAALLRHHNSISVFPLATLRQTLTSALSTWPSSAPLWSIYVQVENRYHSAGRARRFFHSVTRDNSSVVPRLFAIVAEQQRKQLVDAAQRSCCNDAALPILPENGLSNRIRGLFESTIATEMGAHCPLLWRMYMHFLVSEGKVDKATGIFYRALQNIPWSKGLYMDAVQLFPDRLQEFVDLMTEKELRLRLPLEELDILLED"

     misc_feature    463..774
                     /gene="nrde2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(463..489,496..501,511..516,520..522,526..570,
                     577..585,589..597,631..639,649..654,658..663,670..690,
                     721..732,745..774)
                     /gene="nrde2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    964..1968
                     /gene="nrde2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
     polyA_site      4435
                     /gene="nrde2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

cgagtgacgtcatgttcctgcgactgtttatgtgcgataaccaacatggcgctgtttccagcttttgcagatgtatcaaacgacagtaaagttgaagattcgtccaaagagttagaatggctgaaaaataagagttttcagaccggggaggctctctctcttcacaatcgttttttagagaagaccactgaaaggctgagcgagaaggactcaagtgtagacagagatgagaaagaaagtgatgtgccacccaaaaagaagaaaaagaagagtgaaaagcatagaaaaaagaagaaaaaacacaaaaagaagagcgggaggtattcggattctagtgggtctgactctgaaaccatctacccaagtgatctcaaaaaggaacaagaggcagacaggctccaggatgctccgttagcaagtcgtttctcctggttggatgacctcaagttgcccacagagcagccattctgtgtggacagtaaaccagacccagccaactggacgtacaagtccctgtacagaggagacgtagcaaggtataagaggaaaggtcggtcgtcgttgggtctggacccgcgcagacaggaagtcagctgggatgagtcagagtcaaataagaaacagaaaggcggggacaagaagaaagcagcagacagatacttctctacagtcagtcgccagctgctcaggtcccagcaccccgttcctacgttaccaacgattcctgagtgtagtgatgtcatcagccccacctccttcctccccctgggtgatgatgagggggagaacaaaggaggagagacaggtgacagagtgcagacatcctcagtaaatcccctcggtgtgtacgactcctctacgactctctggctgcaggggaagggacagcaggaccagacggagcatcaaaagcaggacaaacagacagggcagagcgctaaccttttggccgggaggactgaagagtttaacaggcggctcagagagcagccagcagatacgcagctatggatacaatttatacagtaccaggatgagctcagtgcaacagcgtttggaggtgaggaggagcaacagggcacagattcagctgaacgtcgtaagtcttcctaccgagctgtcctggagaaaaagctgagcatcgcagagcgcgccgtggccaccaacccaggctgcatcgctctgcagctggagaggctcaggatctgccaagagctctgggagccatcagttctggctaaggaatggaagaaactggtgttcctccacccaaacagtgccctcttttggagggaatatctgctgttcactcagagctacttcagcaacttcactgtggctaaagtcaactctgcctacgggaagtgtctaagcacgctcagcgctgtgcgggacggcagcatggtctctcacccggccctgcctgggattgaggaggatatgttggatatcttcacccagcagtgtcatttcctgcgtcagtgtggtcactcagagaaggcgatttctctgtttcaggccatgatcgactttactttctacaaacctgaaagcgtacaaaagatgtccaccaagcagcaggtagagttctttgagccgttttgggacagcggggaggcgagagttggggagttgggggccagaggttggaaagcctggatgctccaacaagagcgaggagggtggctacagcccagtgcagaggaggatgaggaggaggaagaagatgaagaggaggtgaaggatcggagccagcccagatggacagtctggctggatgtggagtcgtctcgcgaagcagctcactggttgccctggagacctgacaaagccaagggccaatcggaagaggactgtgacgacccggacagacaggtgttgtttgatgacatcggctcatccctgatttgtctgtcttcaccagagctccagctccgtcttgttctcaatttcttgtcattcctggggcttcctgtggactctgctgccccctgtcagcttggcctgttgctggagagcctgtcactactcactcagggtaatgatctccagcgtcctctgacctcccacgacctacctggccccggggttaactctgtaggtcacatgaccactcttcagggaaccaggaagctggcggggcttgggaagcacggcgagaggtttgtcaccaatgtgttcaatatggttcaacctgtccttcctgcccaccaccgagctgtcttatcactcagctggatgcagtatgagaaactcaaggtcttgcgctgcctgcgcagcggcaacaagaagcgtctccgctctcagggcaagagcagcaagcgggttgccaaacgactgctcaaagaacctgacaaccgctcatcgttgatgctgtggcgggagtacgcccacctggagtggatgctgggtaaccttgacgaggctcgcaaagtgttctccacagccacagcgatagggggaaccaaagggctgagtagccccaccctctgtgagctgtgtctgctgtgggcccagctggaggtggaggacggagcaagtgtgcgaggagggggactaagtgatgtaaccgcgtccccggctgtgtgtgtactaactaggctagcagaaggaacctcctcatcatcctcttcatcttcccagtctctctctccagtttccatcctgaaagcaagaaagtcatatgaacaagctctgactgccagcttggcagcactggatcaagacccccacaaccctcaggccaacagaaaaggtcaagaggacttgagaggtctggtcagctgctacgctctgttccagtacctcacggtgggcatccaagcagctcacactgtctacagtcaggcaagagagaggatggaggagctgcaccgcacgctaacatttgacaagcagctgagcagtaatgaggaagccaaccttgccagcactgatgccagtcactctgcagctacttccggcccgacaagcaggcagtgtgttaacaggctagcctctgagtgtgagatattagcagtacagcacgcagcattgctcaggcaccataacagcatcagtgtgtttccactggcaacactgagacagacactgacatctgccctttcaacctggcccagcagcgcccctctctggagcatatatgtacaggtggagaatcgttaccatagtgctggccgggcgcgtcgcttttttcactctgttaccagggacaacagcagtgttgtgccgcgcctctttgccattgttgctgaacaacaaaggaagcagctggtggacgctgctcagaggtcttgttgcaatgacgctgccttgcccatcctgccagagaacggccttagcaaccgtatccgtggactgtttgaaagcaccatagcaacggagatgggtgctcactgtcctttactttggaggatgtacatgcacttcctggtgtcagaagggaaggtggataaagccacagggatcttctacagggctttacagaatattccctggtctaagggtttgtacatggatgcagtgcagctgtttcctgaccgtctgcaggagtttgtagatctgatgacagagaaagaactacgactcagactacctttagaagaactggatatactactggaggactgaacacacacacacacacacaacttgttcaagagctcagtttgagtttgccttgctggcaacatgcccacccacatattggcacacttgatggcaacagcaggacacacacacagacttggatgctcacacacacatcgctgcagtataaaacagcgaagttgcagtgatcttcagatgggcaaggagccattttttgtatatggggcatgaaaatgctttattttcacagcaaaccattatgactgtgttttactagctaagattgtcaataaaactataattttcatttaagtgctgtagttgtgatcatgcataatctgatgagcacacagtgcatacaaactgaggttggcacctgcgtttttaaacaaaataaaacctcatgacatgtttctatcaaatgtgattgcaaagagaacatcaacatttgagtcaaattaaattataaactaatacaaatgaaaaaaaaattgaaattaaacattacacttcctcagcatttaatgataataaagattttttttgctatagtagtaatatggtcatgattataaaatgtcaactttgaatgttcaaatgcaaatgcttcaacttgttcatgctttggacacctcagggttaagaaactccagattatgaggaggttaaattatattttattctaaacctttgtgtaaggcaactattgccagataagaactgaaaggcagatcagactgacagtgccagtcttcacaaagttgtcatttttcacatagtactattttatttattttttggtcaataaatactttgttaaatttca

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