2024-11-21 21:27:50, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS XM_066625639 6629 bp mRNA linear VRT 22-JUL-2024 DEFINITION PREDICTED: Tiliqua scincoides argonaute RISC catalytic component 2 (AGO2), mRNA. ACCESSION XM_066625639 VERSION XM_066625639.1 DBLINK BioProject: PRJNA1136870 KEYWORDS RefSeq. SOURCE Tiliqua scincoides ORGANISM Tiliqua scincoides Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Scinciformata; Scincidae; Egerniinae; Tiliqua. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_089824) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_035046505.1-RS_2024_07 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 07/19/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..6629 /organism="Tiliqua scincoides" /mol_type="mRNA" /isolate="rTilSci1" /db_xref="taxon:71010" /chromosome="4" /sex="male" /tissue_type="heart muscle" /dev_stage="adult" /geo_loc_name="Australia: South Australia, near Adelaide" /lat_lon="34.08575 S 139.05331 E" /collection_date="2019-10-01" gene 1..6629 /gene="AGO2" /note="argonaute RISC catalytic component 2; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 42 Proteins" /db_xref="GeneID:136649184" CDS 57..2660 /gene="AGO2" /codon_start=1 /product="protein argonaute-2" /protein_id="XP_066481736.1" /db_xref="GeneID:136649184" /translation="
MYPAGGAAPAASAPVLATPSLLPPPIQAYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKAQIFGDRKPVFDGRKNLYTAMPLPIGREKVELEVTLPGEGKDRIFKVAIKWMSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPFVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKTFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA"
misc_feature 321..578 /gene="AGO2" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 606..758 /gene="AGO2" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 759..1121 /gene="AGO2" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(915..917,960..962,1002..1004,1014..1016,1068..1070, 1089..1091,1095..1097) /gene="AGO2" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_feature 1254..2531 /gene="AGO2" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the...; Region: Piwi_ago-like; cd04657" /db_xref="CDD:240015" misc_feature order(1665..1667,1677..1679,1713..1724,1731..1733, 1755..1757,1764..1766,1776..1778,1788..1790) /gene="AGO2" /note="5' RNA guide strand anchoring site [active]" /db_xref="CDD:240015" misc_feature order(1869..1871,1875..1877,2085..2087,2499..2501) /gene="AGO2" /note="active site" /db_xref="CDD:240015" ORIGIN
cgagagggagcgagggcctcccgccgccttcagcgtcgccggccgcagccgcagccatgtatccggcggggggagcggcccccgccgcctcggcccccgttcttgcaacaccatcactgctgccacctccaatacaagcatatgcatttaaacctccacctcggcctgactttggtacttcagggagaacaatcaaactgcaagccaacttttttgaaatggacattcctaaaattgacatttaccattatgaattggatataaaaccagaaaagtgccctaggagagttaacagagaaatagttgaacacatggtccagcactttaaagcgcaaatatttggagatcgtaagccggtatttgatggaagaaaaaacctctatacagctatgccgcttccaatagggcgagagaaagtggaattggaagtcacgttgccgggagaagggaaggacagaatatttaaggtggcaataaagtggatgtcatgtgtgagtctgcaggctttacatgatgctctttctggtcgtcttccaagtgttccttttgaaaccattcaggcactggatgtagtaatgaggcatctgccttccatgaggtatactcctgtgggccggtcctttttcactgcatcagaagggtgctctaatcccttgggtggtggcagagaagtttggtttggattccatcaatcagttaggccttcactgtggaaaatgatgctcaacattgatgtatctgcaacagcattttataaggcacaaccagtaattgagttcgtatgcgaagttttggattttaaaagtattgaagaacaacagaaacctctgacagattcccaaagggttaagtttaccaaagaaattaaaggtctgaaggtggagatcactcactgcgggcaaatgaagagaaagtacagagtatgcaatgttaccagacgaccagcaagtcaccaaacatttccacttcagcaggagagtggacagacagttgaatgcactgtagctcaatattttaaggacaggcacaaattggttttacgataccctcatcttccttgtttacaagttggacaagagcagaaacacacataccttcctctagaggtgtgcaacatagtagcaggacagagatgtataaagaagctgacagacaatcaaacttccactatgataagagcaaccgctagatcagcaccagaccgccaagaagaaattagcaaactgatgcgaagtgcaagttttaataccgatccttttgttcgtgaatttggaataatggtcaaagatgaaatgactgatgtgactggtcgggtcctgcagcctccttctatcctctatggaggaaggaataaagcaattgctacaccagtgcaaggagtttgggatatgaggaacaagcagtttcacactggaattgaaatcaaggtctgggcaattgcttgctttgccccacagcgccagtgcactgaagttcaccttaaaaccttcacagaacaattgaggaagatttcaagagatgccggaatgcccatccagggtcaaccctgtttctgtaaatatgctcaaggagcagatagtgtggagccaatgttcaggcacctaaagaacacctatgctggtttgcagcttgtagtagtcattctgccaggaaaaactccagtttatgcggaagtaaagcgtgttggtgacactgtattgggcatggccacgcagtgtgtgcagatgaaaaatgtgcaacggacaacacctcagaccctctccaatctgtgcttaaagatcaatgtcaaactgggaggagtaaataatattttgctgccccagggaagacctccagtatttcagcagcctgtaattttcctgggtgcagatgtcactcatccaccagctggagatggcaaaaaaccttccattgctgctgttgtaggtagcatggatgcccacccaaatcgatactgtgccactgtgagagtccagcaacatcgtcaagaaattatccaagacttggctgccatggtcagggagctgttgattcagttttacaaatccacccgattcaaaccaactcggattattttctacagagatggtgtttctgaggggcagttccaacaggtacttcatcatgaattactggctatccgagaagcatgtattaagctagaaaaagactaccagcctggaataacattcattgttgtgcagaaaagacaccacaccaggctcttctgtacagacaaaaatgaaagggttggtaaaagtggaaacattccagcaggtactacagtggacacaaaaatcacccatccttcagagtttgacttctatctatgtagtcatgctggtattcagggaacaagcagaccttctcattaccacgttctctgggatgacaatcgtttttcttcagatgagcttcaaatactcacctaccaactgtgtcatacgtatgtacgctgtactcgttccgtttcaattcctgcaccagcatactacgcacacctggttgcctttagagccaggtatcatctggtggataaagaacatgatagtgctgaaggaagtcacacctctggtcaaagcaatggcagagatcatcaagcacttgcaaaagctgttcaggttcatcaggatacgttacgcaccatgtactttgcttgacatgttgcagtgatttaaataactcggttcagagttggattcacaggagaccagctgcacttagaccaacagttgcccaagctatagcgacagccagcaatgagtgatacctctttattttattaggtttgaattgtattttattttccattttaaaagaagccttccgtccaaaatttcagacttgatttcaaactgctgacattacaaaaattgcacagctattagaagtgtggatttgccaaaagcaaagagctttttaggagaaaaagaaaaaaaatcaaaccccatattttgtaacagaaacaaaagctgtgatctcagggcttaaacacttcattaagttatgttgttctccttaaatatttgtttttaactaatctgaaaagaaccagttaagatcagttttaatggactgatataaagctatgaatttgctttggtttctgaaaagaaaacagagcgctaatgtgggtaccattgaaaagcttgatcattctggatgaattcatttttttaatttttaatttttatttgtaattgcaatgcaaaaggagagaaatctggtttatccttggctgtcttatttcagtgaacagtctgtatgggtctaagggcaaaagtattttctgaagttcttgaatgtctttcattgtgctgcgtttaaatttttcatagaatgaattatggaaatatttcaggaagaaacaaggagattattatctatactttttattaggcccattgaaagataacaaagtgtgccattaaaaaaagtagttttttttcttttttaatcaattttgatgactaatcatggagtttgtcctctaggactgtgacacttaattttccaaagtttttctaaagaatacgggtctgtggtgatacagtacaatctttttcactgttatgtttgaattaatgtaaaatttatatatgtttcacagtattaacatgatagactagatgctatttatttttatttactaaggcgtgcttaacatgtttctgttaacatatcaagaatgctttggatattggaaatgaaaaccttatcatggggacactagtgattttgggtgcagttcaccaatcattgttttcataagttctctattcttctcaagagggtttgcatggaagaccgctcatatccccttgaaattaatagaggataacttgtggtgatgttttggtgtattgcacctttcaaaagcaggaatatgcaactgacttagagtgatagcattgagagatttatgtatacacatatataatttagcttgtacctggaagactttgaagagttaattcaacagagtagagctaacacttctgtagtttaggcatggacacacaagaacagtccttgagttataagcacacacaaaaaacgatctacctgtttgatcatctgggatatagaagtggaagtatgtacatgagggagaaggtgtccatcttatgtataagggaaactcagggtccagtcctatccaattttccagcactgatgcagcctcaattcagccttgaggtaagggatcaaacgttccctttattgaggaggtctctgttattgctttccccaccaccacaggatgaagtgcatgccccattggcatggcctcatcagcactggaaagttggatagaattggcctctgagtctggagggtttgccattctatttggagaagcattaattcaaactgagacctactgagaacaaaaacttctgtacatttgcacagagttcatataaatgattattcacagacacccattgcactaatgacaacaggaacactaccaagatatagaaaaaaataagtttttctcctaatctgatctcgttggacttttaaatcagacaaaacagcaagaaaatgttacatatcttttaatttttgaaacattcctaagatttcttagaatttattttctttctcctggatagccaatgttataaaattttagtgcccatttctccattctgagaattgggaacgaggggttaggctgtgctaggcttattatggtggtatagaactgatagttgatacctgtgttaaaaatgcttgaattgttgcctattaaattttagggatctgacttctgcacctagtaaacagtgcctcatgttcccaaacagatgtggcttgaacatcaaggttttgaggcaagacagtgtcacgtgcgtttattctttttttaaagtgtgtgtgtggtgttgttttttttaatctggacattgcagttccagcagcttgataagtaaataggatcccgccagggtctctatcattatggaaagtaggttgtcacatccttttcttaacacgtagtgtgtagctcctttgtggatttgttgcactttccagcttggagagatgttgaaatgtgaaggtcatgttcaagtttgactacgactcagtaggtgaacacgctgatcttttaaaagcttatctcctgcttttgaagttatgtcctgattagccatctgtcttaatcaggcacttgagatgccaaccattcattctgtccttgcttttctatcaccttgaatctaaatctggcaaaaagtgataggctaggatgtgaatcttagccagaactgagtggcctggttatcaaggagccctgtctcatggctgttgttgactagcattttcaacccttccattgcattgccagctccagaatataaatgtgtgccacagttgttgtcaggtgcttgtgtaggtgactcttctgtagatagttctccaaagaattaatgttgtcttgtcactggcatgtgcaggaactttgtgtgtgtgcgtgtgtgcgtgcgtgtgtgtgcctttctgtgcagaagaaatatgatggttttgtgaagattaggtatgattcttgggccagaaaggagaaatctgtgtgtttcgttatcttcccttttcttttaatcttgtatactgtattcttaaaaatgacttttgctttttctgtgctagatgcatggcaaactagtgtctaccacattttaacatccggggaggggggagggattgtaaaacgtgttttgaacagctgacaatgcactttgaaaaagtagggcactctaaatatgcacaggaattgctttttataatatatgcataaaccaaaactccaaattgaaacaaagaatacacctttctcaatagctgtttactgcagtggctcttgtaagcacagcaatatctcaggtgaagaatttcatacatttttatccaaaatatcctctgtggagagcataggagaatagtttacaaaaactgaggcggagtccaggatagttacgtgtacctggggatccaatctgttaccttttatctttaacatcgcttcataacaaaactggttttaacccacatctgcccatatgccctacaggcagcacctatatgttgcatgtgtagacccgcaggcaaagatggctgtctttttggctaatttggctttaaagaaaatgcctctctgtccactagtgaggaacctggatctgatcatcacatttgtagtcagtggaaggaacagtatgcatttttagtgtcatggtcttattaatttgtcgtaattgataggagttggcactggtatgtgcagtttgtagccaaagaggtgttgcaaaattctattccctgggattgctgcagtttttgtcttacttcatcctcaagggttagactgtgctggatgcttacctgtgctattgcctggactattctgcttggtgctttaaactacatgcaacacctctttaatatggaagaatagagccgatagctttgtcaaagccagagctgtgttgttggtttcacactgccaagtcagaaccctcatcttgaaggaagcttgttggaagtgttagcaaaacaaaacacccacaagatttgagtctgccaggttaatttagagtttcctgctttatttgttgtaaaat
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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