2024-11-21 22:28:37, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS XM_066265603 12102 bp mRNA linear MAM 05-JUL-2024 DEFINITION PREDICTED: Saccopteryx bilineata argonaute RISC catalytic component 2 (AGO2), transcript variant X3, mRNA. ACCESSION XM_066265603 VERSION XM_066265603.1 DBLINK BioProject: PRJNA1130893 KEYWORDS RefSeq. SOURCE Saccopteryx bilineata (greater sac-winged bat) ORGANISM Saccopteryx bilineata Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Emballonuridae; Emballonurinae; Saccopteryx. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_089492) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_036850765.1-RS_2024_07 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 07/03/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..12102 /organism="Saccopteryx bilineata" /mol_type="mRNA" /isolate="mSacBil1" /db_xref="taxon:59482" /chromosome="3" /sex="male" /tissue_type="liver" /dev_stage="adult" /geo_loc_name="Suriname: Sabajo" /collection_date="2017-09-20" /collected_by="Burton Lim" gene 1..12102 /gene="AGO2" /note="argonaute RISC catalytic component 2; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 3 Proteins" /db_xref="GeneID:136329440" CDS 210..2558 /gene="AGO2" /codon_start=1 /product="protein argonaute-2 isoform X3" /protein_id="XP_066121700.1" /db_xref="GeneID:136329440" /translation="
MVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGREKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGILVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA"
misc_feature 252..476 /gene="AGO2" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 504..656 /gene="AGO2" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 657..1019 /gene="AGO2" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(813..815,858..860,900..902,912..914,966..968, 987..989,993..995) /gene="AGO2" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_feature 1152..2429 /gene="AGO2" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the...; Region: Piwi_ago-like; cd04657" /db_xref="CDD:240015" misc_feature order(1563..1565,1575..1577,1611..1622,1629..1631, 1653..1655,1662..1664,1674..1676,1686..1688) /gene="AGO2" /note="5' RNA guide strand anchoring site [active]" /db_xref="CDD:240015" misc_feature order(1767..1769,1773..1775,1983..1985,2397..2399) /gene="AGO2" /note="active site" /db_xref="CDD:240015" polyA_site 12102 /gene="AGO2" /experiment="COORDINATES: polyA evidence [ECO:0006239]" ORIGIN
gccgccgccgcctccgcccgccgcccgggccgcgtcgggtaaacctgtttggccaggcggccgcgccggggcggatcgtgcggccggcggctccctcgcggctcgcggcgtcggggcccgtggcgcgcgcgcggccgcccctcggccccggagcccctcggcggcgccaccatgtactcgggagccggccccgggaaatagtggagcatatggtccagcactttaaaacacagatctttggggatcggaaaccagtgttcgatggaaggaaaaacctctacacggcgatgccccttccgatcgggagggagaaggtggagctggaggtcacgctgccgggagaagggaaggaccgcatcttcaaggtgtccatcaagtgggtgtcctgcgtgagcctgcaggcgctacacgacgcactttcggggcggctgcccagcgtcccctttgagacgatccaggccctcgacgtggtcatgagacatctgccctccatgaggtacacacccgtgggccgctccttcttcaccgcgtccgagggctgctccaaccccttgggtgggggccgagaggtctggtttggcttccatcagtccgtccgcccttctctttggaaaatgatgctaaacattgacgtctcagcaaccgcgttttataaggcacagccagtaattgagtttgtttgtgaagttttggattttaaaagtattgaagaacaacaaaaacctctgacagattcccaaagggtcaagtttaccaaagaaatcaaaggtctgaaggtggagatcacgcactgtgggcagatgaagaggaagtatcgtgtctgcaacgtgacccggcggccggccagccaccaaacattcccgctgcagcaggagagtgggcagacagtggagtgcacggtggcccagtacttcaaggacaggcacaagctggttctgcgctacccccacctcccgtgtttacaagtcggacaggagcagaaacacacctaccttcccctagaggtctgtaacattgtggcgggtcagagatgtataaaaaagttgacggacaatcagacctcaaccatgatcagagcgactgccaggtcagcgcccgatcggcaagaagagattagcaaactgatgagaagcgcgagttttaacacagacccgtacgtccgggagttcgggatcctggtcaaagacgagatgacagacgtgaccgggcgggtcctgcagcccccctccatcctctacgggggccggaataaggcgattgccacccctgtccagggcgtctgggacatgaggaacaagcagtttcacacgggcattgagatcaaggtgtgggccattgcctgcttcgccccccagcgccagtgcacggaggtccacctcaagtccttcacagagcagctcagaaagatctcaagagatgcagggatgcccatccagggccagccgtgcttctgcaagtatgcccagggcgccgacagtgtggagcccatgttccggcacctgaagaacacgtacaccggcctgcagctggtggtcgtcatcctgccgggcaagacccccgtctacgccgaggtgaagcgggtgggagacacggtgctggggatggccacgcagtgcgtgcagatgaagaacgtgcagaggaccacgccacagacgctgtccaacctctgcctgaagatcaacgtcaagctgggaggcgtgaacaacatcctgctgccccagggcaggccgcccgtgttccagcagcccgtcatcttcctgggggctgatgtcacccacccgcccgctggggacgggaagaagccttccatcgctgctgtcgtgggcagcatggacgcccaccctaaccgctactgcgccaccgtgcgggtgcagcagcaccgccaggagatcatccaggacctggccgccatggtgcgcgagctgctcatccagttctacaagtccacgcgcttcaagcccacccgcatcatcttctaccgggacggcgtgtccgaggggcagttccagcaggtcctccaccacgagctgctggccatccgtgaggcgtgcatcaagctggagaaggactaccagccggggatcacgttcatcgtggtccagaagaggcaccacacgcggctcttctgcacggacaagaacgagcgggtcgggaagagcggaaacattccagcaggcacgaccgtggacacgaagatcacccaccccaccgagtttgacttctacctgtgcagtcacgctggcatccagggaacaagcaggccttcccactatcacgtgctttgggatgacaatcgtttctcttccgatgagctgcagattctcacctaccagctgtgtcacacctatgtgcgctgcacacgctccgtgtccatcccagcgccagcatactacgctcacctggtggccttccgggccaggtaccacctggtggataaagaacatgacagtgctgaaggaagccatacctccgggcagagtaacggccgagaccatcaggcgctggccaaggcggtccaggttcaccaggacacgctgcgcaccatgtactttgcttgacgtgtggtcgtgtttacgattgtgtgccgagttggattcacatgagaccagctacactcagaccaacagatgcccagcccttccgtgacagccagcattcaacacgagacatcattgattttcgtagatctccattttccagaatgccttccgtcccagatttcaaacttggattttgaactgcagacctgtatgagaccccattgtcgtaggaaatatggtttgccaaaatctatgagctgcttactaaaataagagtcccttgtttcctaaaaatctcctaaaagcagtcttatgaactcagggctttaaaacatttttaatttatttggtcatttgattttacttgtttttaacacatgattctatgtgaaattgatgggctcaaactagctgtgaacgttctctgaggacgagaaagcaacacaaaacaattgtggttttaaagccttgaccatcctgatgttcactaaagtctgtctcgcagcgacactcgttgttctcctgacttggctcacacagctcttcgggacccgagggcaggtggccgtgcccgggcccccgtggggcctcgtcccgccacggccgcctcgcacgcggcttgagaggagcggcggtgacacggcagggggccacgcgcgtttacaacatttctaggtccagagagattggcagacaagtgccattttaataaaaatttattaaaaaagaaaaaaaaagaaaaaagacaataatatgccgacagtctaatcgttcagatttgtcctatcggactgtgacattttattttccaaagtttctaaagaatacgggtctgtggcgataaatacagtacaatccttttttcactgttatatgtctttaatgtaagagagaaagaaaatatatatatctggtttgcagtattaatgtgatagctagatgctgtttttcattttattgactacggggtgcttgtgatctgttcagcctatcaagcgtgttctggagcccggagcctggaccgcctctcgtagttctcagtgcttaagtacaggagtatgcaattgacttactgtgactcagcaacctgcccccccccccccccagtgtagaccggcgcctgtacctgtgtgggggctggggaccaggtgcgcgtgcagctgcactcaccgccctttctgcctcctcgtcccgtgtgtcgctcagccgattaagcacaaatggaatgtatgtgtccttctgttcccgggaagccagtccacgtgcatccgagcgtgctcctctctgcgtgtgattctgtgtgacaagtctcgtaggatctatgcactgaaacacgttagagagccattgggtggaggactccgggctgggcgtgaggccagcggtcagcgacggggccctgccctcggaagccagcgcaagggccaagcccctcccgctgggacctgccctcagggctcgggcgtgggtttgccaagctagacagcattgcactaagagtgataccatggacaacttggaaagggtcacaacaggcagccctgactgtgctgagcgggctcttcgtccgcgtaggcagtgtttactgagagtcaagtccacgttcattgtagagactcgaggaaggagaggaaccttccccgcccccaccccgtgctgctctgtgctctgtaggcttcctgtctgtgctgacggacactccccagccggccagacacttacctctctgatgccgtggtggacgacagtcttgacaggggcgcctctgctggagggagcacccacctgtctccttgtccctactccgcggagcagaggggccagggagccggccacaggcgcggccctcgtggacacctggcctggattctggcagcagtgacgaagcgtgactggtccttgttaagctgtctactcagagtggtgtgtgcgtgtgtgcgtctgtgcgtgcatgtgggtgtctcattaatggcattcgtctcttcttgctgtatctactttctgtcttcttaaatggcagaagcctgtgctctaagaaatgtcgcagttccctgtggtttcattggcaagtggcactttctcctgtgttcagaaggacgctggttacactctttgcttagattgccgggagcctccaagctgaggagggaatcttcactaatactctcttaaattaggttggttttcagccattcttaaggtcttcttcaaactgggtgtcccgaaggtgtgtctttctagcacacatgacaggatcttggtgggagggcgactgtggtggcagggaaaatgcagggtcccaggcctcgctgtaaacctcctggtccggggctgcccgaggtctgaccccccccccacccgcccggcagtctagagctttctggagagggcttttccctagagcatggagggcccagcagggaggaactccttggcgacagagggagacgttttctaagctaaaccctagaatagattgcaggcaggctggcagaaaactagacctaaattttttaaacattttattttgaaggcagttttcttttcggtgggccaaaggactttgtgaaaggtactttctacatagccccccgcttgttctgtgaaactttgcatactgaaggcattgaccaaccacacgtctccctctgggtcggccgcgcgcctctgtacacgtctgatggttccgaattcgaatggccgtaggtacactctctcaggtaaataacagatttcccaaatttctaccggtcccctcccccatgtcccgttattaggataaattttgagttctgatggcgtaagacctcacagtgcagtagaaccagtccaggcccggttcgtttggaagccagaagggggcccctcgctgtccccttgagggctaccttaggcccaggccaaggaggggctcctgcatttggcggctgactcccccacccctaccgttagtaaggtgtgccttgcttgaagcaaactgaatgtgaagatgaaatgatgatgtagaaatcgggattcatatcaaagagaaactgggatttatctcatctctttaaaagagctctcgcaattagattcttctcttggtcctcgtcatagtatattttaaaatattcattctggggaaaatcagtctattcccatccccccaccaccacccgctgcgttggacgagttcccaggctagagaaccccgaggaagccgtccaagtcgccattttgcagaagagcccttgggtgacgctaggtcttcatgccgttattgtaccataagctgtatttccctagctcagataaattcggtaaaactgagaatggctatcctcttagaaagtgatggttttatcttgttttgggttcaggttttctgttttgaaaagtcctcacacatacacttgacttactggatacttacataggagggtctgccttttcttaccaagattatgttgctttttggaattatcctcacactccctcaagtaaatgttctccttgatgtgcaccacagacgaccattggctggggcctggccccaagaggggactgtcagaatcgagtgacatctgtgctgtttggggttggccgagagtgcctctgtccctgacggcccctggttactgagtgctggctagaaaagaggacttgagttcagtccctccagcgggtggggcaggtgggggtcattggtgttgtattatgtgttgttcttattgttgttaaattcaaatgttgctatttatttttgcctttctgctctggtttgatttggccggtggatagtccagtgcatgtggtacctgacagatagggtggagactattttccccagctttttataaattgcctaatgcctaccttcaggtttgctggatgatttatttttgaaagccacaaatgtaatttttctggatgaattgttttttcttatagatgcagcattgtagttttacattggtctgtggggtggtttaaatattatttttgcaaggccgttttctcagtcaaattatatatttgatacaatatgtgaagggtggacgagccaagcgtcatgcagttgggacaccagactgtccccaggaggcctgcggggctgggacagcttctctgcccaatgccatggaagcacttggcttgcctccccggagctgttaggatgtgggggtggttcttaatgggactttgagctgttggacagttaaaaggattttcatgggcatttttcctatacctaaggcagttccattaggaggaactttagaagttgacataatcccgacagtggacaatcccggcggcccagacaagccatagaaatttccctgtgacctctgactcatctctcctccacgctcacgagaagaggaatgtacagtggacagaaacttcctcggtgtgcgtacgcctcactttcaagaatgcaactcattttatttatattttaaatccttccccaaagtaactgagaatattccctcttgcttcagctgctgtgacgttttcagtgtagacaccgcacacacgtgtgactttgtgtcatggggttgtccgtgtcccacacacatgctgacttttttttttttttttttttttttggtaaggcaaattttcaactcaaaataattgcactgattttgacaacatccttttgaattatgtccaaccttgcacctgctgtacttgtttagcgattgtaaatagggttagggttagcagaggtgacatgaatgcaaacattgctttgtttttagtggcactgtcacgttcttcagtattacgtgttgcgagttgtggacttggttctgtgctgtagccttgtgtctgctgaccattcatgaaggacaaattagcctctttcctcgtgttcctaaaaggccgtgtttgtaatctgtagaaaggagtgtgtgttcgttctccttgaggtcggaagattgaatcctaagaggattacttgtcaatcctcggaacactcttgtggcttattttaaatctctgtgtttttttttccacaacccccgaaagcattttcccctggtcccgcccagcgtctgacgggctcggtggtgagccacccgtgtggcccatgctcggagagtacaagcaccccctgcttctcctcggccagctcccgttttaaaggcatggggccactgttgtgtcaaaaccagcgctgtttctctagtctgtgattgtcgctagcttagtcgtgtttgctccaacccccagtgtgcgaccgttcgcagtcacccgggtgagggtgacaggcacgccggtgctgccacggggccctcacttgatgcttttctgggtacgtctgccatgttactgtcctcagtgaatgtactggcttagccaaaacactacagaaagtggtttctgaataccttgtcgttaacaaaaaagaaacgcagaaaaaggctacctctgaattctttgtaggttcatattcactcttatgtgtaggtacccaccctgaaaataacgaaaatgttgcccgaataaactgaattgtgaacatctctctgtaccgtgctggcttgaacatttgcgtgccatactgtgacccccgtggtgggcaggcgtctcctcgtgggccgtgggggaaccggcccgccgtcctggctcctcacttcctgtcccgtggaaggaagccctgtcctctgctttcacttccctgggcttggaaacggctccctctgccccctcctccttcttccaccctctgtgagctcaccacactgtgtggccacccactctgccgcaagtcacacacatttaaagcagctctaaggtttgaaccatagtacaggcacagccgacctttgaccttgaaccttttaagcactccctgcttaaaactgatctgaggttcccaagcagaatgtccagttcaagtccacggcgctatgttcgaaaggaacatggggagttaggacttcccatgccctgggtcctccgatgccagctcagcggaagcctgccctgggcgtcggccaggactctgagtgcccctgagcgatctgtccctgtgctgtggagacgtcctcgccctgccctgcggcgggccagccctcattctctgcctcctcgctcctgtcttctctttggcttccgtgtgtgccccccctcggcaggtccccacttgctctgagggactcccttggttgctcttttgtcctggagggacaggcaggtggttttgcagtgacagggtatctgggtgcgtggagggaagttctgctctcctactggacacccactggctttagagcagagagttccggtcacctcacgacatgggagtagctgtctgtcccctcaccgtttgaggggtgatcctcctccagctacctggcgtgcttgaactccaaaagagctaagtgtcctttgtggtctgtcgttctgctgggacgctgcccgccccagggcacctgggtgtgtgcccatgtgtctgctggctgtccgggctgcttgggtcctctgggccagcctcactttcagccaggaccccgtctggggtgtttgaggggtcactgctcggttccgtaatggggaccgatgaccttggatctgcccgtcagccacttgtctcagcgcatgtctccagaatccagaggtgggtctaacccgccacatgtactttcatgaaagatggttcagaaaggagaactgaaggtcattggtgcttttgttaacttttctgtcttactggttgatggggaaaattctagactactgggatccggaaatcccctgggatggtgtgatccgagggttgagtccttcccttgccccgcccccttcctatgggtggaggggctgaatcagctactttcttcaagccccctggatttaagcagtgcagagttaaagctgaaacaccaaatattaactcttcccctcaagtgactgcaggagctagctgtggatgccagcctcactcagcaccccgagtcttcaagggcccgcccgtcacggggtgaccccaagagcccacaccaccaggctgggtggggacaaccctgacgggcggcaggaggcaggcccctccggtctctattgggactagaccacgcgtgtcctggaagacccagtcccagcctctgtgcctttcaagtcaggtccacagtgtccttgcagaaccacaccgggctgcgtttccactgggcggtaagcctggaccgtcccccaagtcagccatccaccttctgccttcagcgctgcttccgctcctgagctcccgacgtggtggactgccgtgcccgtgcgtgctgtctcgtgtcagaaaacgtgatgttcccatcgcgtgatctctcccgggccccggccaaggcctcccctgcagagatcccagggagaccttagcctggctctgaccacgaccataagcgaagcctggtggttttgttcagtcactcaacgcgtggttagtgttttggacctttttccgaggagttggaatctttctttgtgaaacgtgtgtggagccctcagctgtaaggtgttatccggtcctgctgtcctggccggggaaaggttccgctagtgttgcttgtgacgttcgggagactgcttgcttgagtgtggctgtcagcttgggctgcgcacacaggactacagcttggacacacctacaatgcaatgtgtagctctcactgctcctggccaggtagtgagcactttcttggctgatgatctaattaaaaaccacccttccctgtggtgaccttacaggtttgaagcgggggagataatctgatggtatttcacagtgtatagacaagccgccttgatggcttctcttggccctcccctcacccggagcccctcccctccgttctcagcggcactggctgcaggggggacgacacatccgaagtttgggttcctcttcaaagccaaatacgcacctgactaaaagcctggaagtatgtagtttagcactaaatttgaaatttgagtcctgagtttgatagtggctttaatgtagttgttgaaggtatgaactcatgttttataactgtagaggcaagtgagtttttactttttaaaaagttttaagagaataattgttcgtttctgtgcagcaaagtggctcattactcattaaatacaagaaaagaatgtagagtctaaatccagaattttcttacctctggtacacttcagattacttaacctaatatgtattgaggggtttgaaccctgagttttatcaacttttctagttttattttatttttataaaataattgaaaaagaaccaaaaatgaattcaaaaagttccctagatagatcttaccccttcttaatccccccccacacacacacacacaataaaacactttaagaaaacattttgaatcaaaatgtattacgaccatttaaagtttactattttctaagaagccgagcagctgcaagggcctcactgcaggtggttcccgcgtcccgtctgtgagcacgcttcgcgcctgcgtgtgtctgcctgaccacgacgtcttgtacttgcagtggaagccgtgcagtgctgttttgtaaatcgacagtttctgtataagctagtatttatagccgttggcctctctatataacttttcattggctccatgaattgtaaactttattataaaatcgtaggacccggtcaacacaactcggaggcttcctgtccttgtcttgagtttacttgccttcctgtgtgtctggaggatgtcccatgcttgcatgatgccaggtggcgatgccactttaaattaagccttaatcagatgtccaatttttcagtttgagtatgcaaaaatattaggcagagtgagtttaaactgtccagatcaagatgcgatgccatccttcagcaagtcttttctccagagttacaaagggaaactaagcgatacacctctctctctctctctctctctccctccctccctccctctctctctctctggctgttgccatcgtttgatgaagatggaccattgtgcatttctgtggcagtcagtcaaaaaaagacctgttcttgaaagtcttgaggctttttcagggttgtttttaaatgtttggaacttttttccccctccagtctgaggtggatttatggctgacgaagggtgtgatctgggcataagtcttacctgcaaacttgctcgtgttctaagcttgcttcaggcagtgccagcgccgtcacttctgcatatagatgattacgtgggtttttgtttttatgaaagtatcttaaatttaggcataaaatggaggggacccagctttcttttacaatgtggatctacctcagttaaatagttgggtgctatttactaagtctgtcaaattaaattggagaacgtaaccaaacagtgagagataactccacatgaagcttgaaatcctcatttccgtttatttaataatatttttatttatttttgtgccttttgtgttgaatcctgatgcattggggggggaatcagtataaaatgaaatatattaaaggggggggaagcccaattggccatgatatttgataattccccctccccctcaccgagccggc
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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