LOCUS       XM_051832183            7366 bp    mRNA    linear   MAM 28-NOV-2024
DEFINITION  PREDICTED: Oryctolagus cuniculus argonaute RISC catalytic component
            3 (LOC100356842), transcript variant X8, mRNA.
ACCESSION   XM_051832183
VERSION     XM_051832183.2
DBLINK      BioProject: PRJNA1178637
KEYWORDS    RefSeq.
SOURCE      Oryctolagus cuniculus (rabbit)
  ORGANISM  Oryctolagus cuniculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha;
            Leporidae; Oryctolagus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091438) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Nov 28, 2024 this sequence version replaced XM_051832183.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_964237555.1-RS_2024_11
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 11/21/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7366
                     /organism="Oryctolagus cuniculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9986"
                     /chromosome="7"
     gene            1..7366
                     /gene="LOC100356842"
                     /note="argonaute RISC catalytic component 3; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 45 long SRA reads, 2 Proteins"
                     /db_xref="GeneID:100356842"
     CDS             130..2259
                     /gene="LOC100356842"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X5"
                     /protein_id="XP_051688143.1"
                     /db_xref="GeneID:100356842"
                     /translation="

MSHYLGKVEKIDLSKCQSNLFLGYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    205..357
                     /gene="LOC100356842"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    358..720
                     /gene="LOC100356842"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(514..516,559..561,601..603,613..615,667..669,
                     688..690,694..696)
                     /gene="LOC100356842"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    853..2130
                     /gene="LOC100356842"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1264..1266,1276..1278,1312..1323,1330..1332,
                     1354..1356,1363..1365,1375..1377,1387..1389)
                     /gene="LOC100356842"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1468..1470,1474..1476,1684..1686,2098..2100)
                     /gene="LOC100356842"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      7366
                     /gene="LOC100356842"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

attgcctgcaacaaccgatgctgggccatgtggaagccaggaatctgaaactcaatccacgtctcccacgtgggtggcagagatgcaaatacttgagctgttatctgctgcctttcagggtagatttagatgtcacattacctggggaaggtggaaaagatcgacctttcaaagtgtcaatcaaatttgtttctcggatatacacctgtgggacgctcctttttctcagctccagaaggatatgaccaccctctaggagggggcagggaagtatggtttggattccatcagtctgttcggcctgccatgtggaaaatgatgctgaatatcgatgtttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgacattcataatattgatgaacaaccaagacctctgactgattctcatcgggtaaaattcaccaaagagataaaaggtctgaaggttgaagtgactcattgtggaacaatgaggcggaaataccgtgtttgtaatgtaacaagaaggcctgccagtcatcaaacctttcctttacagttagaaaatggccaaactgtggaaagaactgtagcgcagtacttcagagaaaagtatactcttcagctgaagtacccacaccttccctgtctgcaagtggggcaggagcagaagcatacttacctgcccctagaagtctgtaatattgtggcagggcaacgatgtatcaaaaagctaacagacaatcagacttccactatgatcaaggctacagcaagatctgcaccagatagacaagaggaaattagccgattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcagtttaaagttcgggatgagatggcacatgtaactggacgtgtactgccagcacctatgctccagtatggaggacggaatcgaacagtagcaacaccaagccatggagtatgggacatgcgaggaaaacagttccacacaggagttgaaataaaaatgtgggcaattgcctgttttgccacacagaggcagtgcagagaagaaatactgaaggggttcacagaccagctgcggaagatttccaaggatgcagggatgcctatccagggtcagccttgcttctgcaaatacgcacagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgccagggaagacgccggtgtatgcggaggtgaaacgtgtgggagacacccttttgggtatggctacacagtgtgttcaagtcaagaatgtaataaaaacatctcctcaaactctctcaaacttgtgcctgaagataaatgttaaacttggagggatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagcagatgtcacgcatccacctgctggtgatggaaagaagccttcaattgctgctgttgtaggtagtatggacgcccacccaagcagatactgtgccacagttcgagttcagagaccccgacaggagattattcaggatttagcttccatggtccgggaacttctcattcagttttataagtcaactcgattcaaacctactcgtatcatcttttatcgggatggtgtttcagagggacaatttagacaggttttatattatgaattattagcaattcgagaagcctgcatcagtttggagaaagactatcaacctggaataacctacattgtagttcagaagagacatcacactcgattattttgtgctgataggacggaaagggttggcagaagtggcaatatcccagctggaacaacagttgatacagacatcacacacccatatgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgtccttcccactatcatgttttatgggatgataactgctttactgcagatgaacttcagctgctaacttaccaactctgccacacgtatgtgcgctgtacacggtctgtttctatacctgcaccagcgtattatgctcacctggtggcattccgagccagatatcatctcgtggacaaagaacatgacagtgctgaaggaagtcatgtttcaggacagagcaatgggcgagatcctcaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtactttgcttaaagagtccacatatattttctgagaggaaaaactgaattgacatatgctgtatgtttccagtaaagtcaattgagtagggagcgacgcctccagccgtacagaaaccaacactgtgtcgggccagggtctgatccttctgctgatgcaaggaagagtgtctgcttcatcaaggaaggcggcactattatgcaatatgaaaccagccactgctttttgtgcagtctccgtaggaagtattgcaattgttttgttttcacttcttatagtctaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaagtaggaaatgtaaatgatggtttaaaaaacacacacctatgtgaataatcaaagtgattgttcacaattatgtgtgcaaaaaaattaatgtgcactcgtatattcttgtaaaaggagtctgtatttttaaaatatatacatgtatacttcatgtgcatatatatctgggtctagattgataatagatatatatgtatctgtgtatatattttatagctcattccattgggaaactatctttccctttattctctcctcactaccacctttatttctctgacatcccttgccttcatcacctgtattttttctcctaatgccaccagtgacattcaaatgttcatatatctaattcatttgaatgtgaagcatagcaaactagatttctatttttattttgcacatccttttcctgtctcctatctcatacagttttgagtcctcaactcctgatagtgctttcttaagaaacagaattattttatatctatctatatatacatatatataatgttttggtgagattgtgtgtctcctgtctgaactgaacatttgccacttgtgcaatgtgtacataagcagtagcaatctaatattctttttctttagcgagtttgttaaagctgctataaatatgaaaccttgtcagaagttgtaactgtttctctctgataagtggtatctattctaaagcattctgtttctttgggatagacatggaaatcccttaaagcttttataaaggataaatattttaagaggttggaactctgtagggttgaggcctctgaaattgggtagagaaagagaagaggctattggaatttttgttttgttttgattcactttttgctaggtaacttgctgcgtctcataccttaatgtgattttcatatatatatttttatatatatgtatatatataaacatatatgtatgtgttttgaagtatagcttccttttcttttgtatttattagaatagtgctttaataattacagaaccatattaacatcttttatagaaatataatcatgtttattttaagaactgacaacttgtttttgctgccttttagtgcaataagcagttttaaaagttgtgtctttttgacatctctaccatggataatgggaggaataggcacctccgtaattttacaagggcaaagtaatacagccttaatttcagaaggaaagttttctaattttcagttttaaagcatatcttttaaaaatcataatgaaaatgaaggaagtgaaatttcttgactgagtttaaccttcagtcttaaagttgaactttgttttaagaaatgacagtaaacagcttaagatttaaaagatatttaagaaaatagatcatgtttattgaagaactgtactggctaggtgccaatttttacttactaaaatgaatcagaaaaatgaaagatgatattttaagaagttttttgctgatttaccaccagtgtgactttccttttaaaattaaggtgatattggcgaaggaagtcaggactttgatcgttttaaatgatttaatcactgaaatgtgggggcaaattttgcagtcttgtccattgatttcactttaagatattaaaagtactaagaatctgtcaaaactaactttatcaagaacattggattcaggggagctttgcactttgtaactcatgaaaattacattttgactttttttttttttttttttttttgcactggttaagagtgtaaatactacagattgtttccagtgggcattgttgttagcctctcagaattccatctgcacatgaaaactaatggatttagatctttagtttgtctcttacttgtaatccactaatattgccaatttactgtattttgagcctaaaatctgagcccatgtcctccaacaggcatgaaatcttttggcccgaagccagaaaactaagaaagtactgtattttgtatgtttattatttttgaagtgtctgaaatgaaatttacaacactgttgcaaagcactttacataataatatttatatagtatatacttttttttctcccagccttctgccttcttctcaaaaaaaaaattcctttaaaacatgtttgttttcttacattgaaacttcactgaatatagtcaggaacatgcgctagagaagacagtagcatattctgggtgaaacaggtttggtctgtgcttgcttggaatgagtaaaacatctttctttatccatgggagctgtatagactggtgtgggaagcttcagggagcaactgtagataccctttcactactccctgctgaacctaatctgcagccacttagtctcatatgtgctagagtgaagcccttaatttaaatgtacttggagggacttttttaagaggaaaagtattttttctaaaatataaagctttaccttttgagtgatttcttttttagagtgtcttacactatccaacattgctagtttaaggttgattaacttgaaagaatatgtataatatatttctattttgcttactaacaaattggtatataaacctaattattaaaaacccgtgcttagcattttaagataaaggctaagtggcacatcttgaaatttgttctaattattattgcacttttggtgtagaattcctgatcttttcttaccttaaaattttaaaaaggttgttatgggtttctttttaaattcagacatcataaaactcacaatgacctttctgcttcttcccttgctcattaattatatattgaatgctaaattttattctactattttctgtgatatgtcatacaggagttactttaaaatgtcaatcccagcaactgttataaataattttcatgtgaagaaatgttgggagtttacgtatattcttaatggcaatgtctgtgaaaagtgctgatacatgttcttacagtatccagtgactggcattgaggaccacacgttggtaatcctgtagctgctatatttatttaagtagagtctgacagttagtgcactaaaccgttaaggagatgaacgtgattcaaggctagtgttacgcctgttgttttgttttgtttcattttcttaaattagattaatgacataaaatcatcaaggtgacaaagggtgctgccattttagttacaattcaataaccagaatattattttagaagtatagtttttgacttttacagtttgcaaagggtacctcagcctcttcagtactggtttttggcacattttcacagaactagagatgccctttctttttgcttactagttaccttttaaaaaatttcttgggaaaatcgttgtattgaaatattcctgtttataccctattgatttatttttcttcctagaagagattctagaaggaattttagtagaaaaaaataaacactacgtgttttagagggcacttgatgaagattatctctgccttgtagcctagggacttgcagcctctaaagacctgtcctagttttttgagctaagttctctgtgactcagcactacgtgatgttccttgtgggttctctatcggagttcatcaggacagaccggacaggcagtcatggaagtcttaggcatgtctagggaagtaaaagctgagctgccattcagcagaaatggctggcagaggatctcagagcgccgggcacggatgtgaggtgttcatgtaggttacagaccacatggttagagaccatttccaaggaactctgcgggtctttccagaggccaacatgcatttgccacaggcagtgctttttatgaaattcaagaagctcatcacttggacatagctaaaatattttgtagtcttcctatttcaaacttgagagtaattttaggccaagaagtttgactgataactctgcatagttttcactgggtatcgataaactggagttaaatgtgtgcttagctcctcctccccagtgtgcacctgttgaagaggaaggctggtgttaacagtgacttgctacttcagttactgtttatgaattggccaagttgcaaaaagacatcagcagttgggcatctccattttttttaagatttatttatttgaaaggcagagtttcagaaagagggagatacacaaatacagagtgagagagagagagatcctccatcccctggttcactcctcaaatggcctcaacagccagagtgagccaacccaaagctaggagccaagagcttcttctggatctcccatttgggtgcaggaacccaagtatttgggctatcttctactgctttcccaggccatttgcagggagctggatcagaagtagggtagccagggctttaaccagtacccatatgggatgccagcactgcagatggcagctttcccaccatgccccctttattttgactttctaatctgtctgaagtattagtccttttcattctttttgagaacttgtggatgtgttaaagcagaggtagtaccattcagcctgtgggccgtataatcattttgtctggccatgccaaggcaactgcaggctagttttaagttgatcatttgtatggcccgcaaatgatgttataaatatccaaaagcctctgggtcgaaaaaagttgccccacccatgctttaaagcatcagtagtgatggctgagaggtttcacattcgagtgaggccttcctgagtggtagtatgaacctgatttagggtctctccttgttgtcctgtttccctcccattggatcatgtaaagcacttatgggattctataggagtcaaaaataagc

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