LOCUS       XM_051832166            5822 bp    mRNA    linear   MAM 28-NOV-2024
DEFINITION  PREDICTED: Oryctolagus cuniculus protein argonaute-4
            (LOC100357099), transcript variant X4, mRNA.
ACCESSION   XM_051832166
VERSION     XM_051832166.2
DBLINK      BioProject: PRJNA1178637
KEYWORDS    RefSeq.
SOURCE      Oryctolagus cuniculus (rabbit)
  ORGANISM  Oryctolagus cuniculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha;
            Leporidae; Oryctolagus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091438) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Nov 28, 2024 this sequence version replaced XM_051832166.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_964237555.1-RS_2024_11
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 11/21/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5822
                     /organism="Oryctolagus cuniculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9986"
                     /chromosome="7"
     gene            1..5822
                     /gene="LOC100357099"
                     /note="protein argonaute-4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 70
                     long SRA reads, 1 Protein"
                     /db_xref="GeneID:100357099"
     CDS             129..2117
                     /gene="LOC100357099"
                     /codon_start=1
                     /product="protein argonaute-4 isoform X4"
                     /protein_id="XP_051688126.1"
                     /db_xref="GeneID:100357099"
                     /translation="

MWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA"

     misc_feature    180..542
                     /gene="LOC100357099"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(336..338,381..383,423..425,435..437,489..491,
                     510..512,516..518)
                     /gene="LOC100357099"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    681..1988
                     /gene="LOC100357099"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1092..1094,1104..1106,1140..1151,1158..1160,
                     1182..1184,1191..1193,1203..1205,1215..1217)
                     /gene="LOC100357099"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1296..1298,1302..1304,1542..1544,1956..1958)
                     /gene="LOC100357099"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      5822
                     /gene="LOC100357099"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

atggaggtgacccttccaggtacactccagtgggccgttcctttttctcacctcctgaaggttactatcaccctctgggagggggcagagaggtctggtttggctttcatcagtccgtgagacctgccatgtggaatatgatgctcaacattgatgtctctgcaactgctttctaccgggctcagcccatcattgaattcatgtgtgaggttttagacatacagaacatcaatgaacagaccaaacctttgacagactcccaacgtgtcaagtttaccaaagagatcagaggtctcaaggttgaagtgacccattgtggacagatgaaacgaaaatatcgagtttgtaatgtgaccagaaggccagccagtcatcaaacttttcctttacagctagaaaatggtcaagccatggaatgtacagtagctcaatattttaagcaaaagtatagtctgcagctgaaataccctcatcttccctgtctccaagtgggacaggagcaaaagcatacatacttgccacttgaggtgtgtaacatagtggcaggacagcgatgtatcaagaagctcacagacaatcagacttccacgatgatcaaagccacagccagatctgctcctgacagacaggaagaaatcagtagactggtgaagagtaacagcatggtaggaggtcctgacccttaccttaaagaatttggtatcgttgtccacaatgaaatgacagaactcacaggcagggtgcttccagcaccaatgctgcaatacggaggccggaataaaacagtagccacacccaaccagggtgtctgggacatgcgaggaaagcagttttatgctggcattgaaattaaagtttgggcagttgcttgttttgcgcctcagaaacaatgtagggaagatttactaaagagttttacagatcaactgcgtaaaatctctaaggacgcaggaatgcccatccagggtcagccgtgtttctgcaagtatgcacaaggtgcagacagtgtggagcccatgttcaaacatctaaaaatgacatatgtgggcctacagctaatagtggttatcttacctggaaagacaccagtatatgcggaggtgaaacgtgtgggagacacccttctaggtatggccacccagtgtgtccaggtaaagaatgtggtgaagacttcaccccaaaccctctccaacctttgcctgaagataaatgcgaagctcggagggattaacaatgtgcttgtccctcatcagaggccctccgtgttccagcagcctgtcatcttcctgggtgcagatgtcacacaccccccagctggagatgggaagaagccctccattgccgccgtggtgggcagtatggatggccaccccagccggtactgtgccaccgtgcgtgtgcagacttcccggcaggagatttcccaggagctcctctacagtcaggaggtcatccaggaccttactaacatggttcgagagctgctgatccagttctacaaatccacacgcttcaaacccactcggatcatctattatcgtggcggggtatcagagggacagatgaaacaggtagcttggccagaactaatagcaattcgaaaggcatgtattagcttggaagaagattatcgaccaggaataacgtatattgtggtgcaaaaaaggcaccacacacgactcttctgcgcagataagacagaaagggtggggaaaagtggcaacgtaccagcaggcactaccgtggatagcaccatcactcatccatctgagttcgacttttacctctgtagtcatgcaggaattcagggaaccagccgtccttcgcactatcaggtcttgtgggatgacaactgcttcacggcagatgagctgcagctcctgacctaccagctgtgccacacctatgtgaggtgcacacgctcagtctctattccagcccctgcatattacgcccggcttgtagcttttagggccaggtatcatctggtggataaagatcacgacagcgcggaaggcagtcacgtgtcaggacagagcaatggccgggatcctcaggccctggctaaggctgtgcagatccatcacgatacccaacacacgatgtattttgcctgagagtctcagaaaaaagaacctgtttggcacctcatgcagcctcaaaatgtttcaaatgcctaccacctctagagagagccaagtcgatcgcaggtggtcttctaccagcagctcggaatagttgcactgaatctactttctttgcagcactatctgatgcatcaacagaattgagccattttttttaaagtaatagatactcatagattatcttttctgatgcactggatggaatttttacctcaatgtgcaaaggctgatagcctgaactttttaaaggactttacaagaaaggattctatggaatattttgctagctgtggtgttcaccgcaacccgcatccctctagtcttataggagaagattattcctttttttctgttttcatcaagtggagtatatatggatgagaaaaaccaaacaatctgcttcagttgagtgtaactatttacttgtgtatgttcatggactttttaatggagattcctgacttcgccactgtaaatgcctttaacgagcattaatttttgaaagatttacaaagttttattagttttactactttatatgattgatctctgcagacttgtgctggtgcaagtacaggctgccaggcaatttgcactatatttggcttcagattccgcaggcagttatcttattggattgacttttgtgaatgtgtgacataaacagatataatgcatgtcacagtgacagataacactgccatggtcaaagtactcatgtttctccctatttgaaaaagaaaatagtttttagtatttttccaagttttcaaaagtgcccattctatgctgctgtgtggtttgttagatctaaatgatttttaaacttttctcatagaaagttaactttggcaataaacattttttaagatccctcctcttctgtcccctgacaatgtagttttctagatgagatttcagtatgatttttattagctatttcttatatatcataatctggcaacttctgaaactggtcagaaaagacatatatttccatgcctttttaaagaattgtttttacctcttttatagtcacagttggtgtcctgtcactttattttaaaataagctagaaccaggatgcttccttattggataggctttgccagtccttaaggtaccttgagtgatgctgcaacttgcaaaaacgtaccagcatttaaacttttttttttttttcctgagaatcaaggttactcacacaattacttgcttctctttcaaactgaaatgtacttggtgggttttccttccttttattatactaaatctgtgtagaaaatattgatttttcttcatagattctggattctgctcacagggagatgggattcgtttcttgtctgaacaaagggagctgatctaaagcaagcaccagttaaaacataggggaaagtgtattctgtatttagtgtagataatattttgtgaatggacaacagctacatatacccttggtagttccagccggtgtttcccagcgcagattttactgacttggaattctgcatcccggaacatcaggaatgagaaatggaaagggggataaaaggccccagagccacactccatagagctgaggaaagggtgggggaagagagacacacagtgtggtgagaacagttttctgcctctggaagccgctggttggggaaacactggagcggatggcaaagggtgtttgcttgaactcatgggtcagtccaaatctcttaatctagccttctcaaaatcccagcaatataaagcactgtttttcatcaattgtggaaacaagcctgtaaatacattcaagtttacagttccgcgggctatcgctcagcagcaccgccgacatttgctgagaccggtctccaagttttgtaatgtgtgttgagcccccagctcattgtgatgatgcagacgcccctgatctgaaggtgatgggaagaaagcaggttctgtgactgaagcacaacgtaggcaggagtgaagagatggcagttgttcgtttcgtaagattttccttttttgcaaatacctcacttggataatacaaatcaggacatgttggtgaggggctggctgctgcttttattcacacttgttcagggagagcacagaaaatacccttcagcatggccactctggacccaagaagaggaagaacggaagcttttgtggaaggaggactcaacgagtgaagaactcttggtggctggctggcaggccagcaggcacctgccctgcacggtagtgcctcgggcttgctcgctagtaacgcacagaagtgtcacttctcaccatctcctggcatgcacggaacagggagcaaggcggagttcagggaagtcccgaactacttgcctgcagctgggctctacgcttgaccttgatctacatagtctgtaagacctcagtcagtccttggacactggggcaaatcagtgcagtggtggaggaaaagccaggaggcctatttttataggaaaacaataccattaagggtgcaatgttgtcattttggacaaaagggaagaaaatgatgaagtaggatcattggaaaaacttgttgaggggtgaatctttaaaaggcgatctctgcagagtcagagttgtggcaatacttttgcaagcaagtctgaatgcacagttttaattgaattcggcttgactattcaaataggtaaccccctcaggactgattgaatcgttatgcatgtgtcaatcaatgggaggtgtgcattctctacaagtagtgttaggctgttgggttttctaaatcgcagcctgtttaggcactgtcatgtggtgtgaaagatttaaatgtagcaacgctaatgagtaacaatttagggataaggagcaaggacattaagagagtggtgaaaattcaaatggcgaacccatggttttgttgttgtgagccattgaatcctgagcgatttagacagtgagctagctggtgtaatgtagccagcattctgggcaggcaaaacatattcattcttactgtaaattctatttgctgcttccaaaggtgatgatttacaagcagacgtgttctatacggtctgcattttaggatctggtgcccagcctatatcagagcttaacctacctggctcagatacctctgcttcccaagggaaaagttaatctactggtagaataaggttcaccctctctaccccaccctagcaactctttgtggatgtgctgtaagattttcttgttcaatagcaaggtggtagctctactttcattttaagaaagtggaggctgagggcattgtatcaaaactttcaactccaagaatttttccttgtcaaattcaaggaaagatcttgttattgatgaacattttcttatcccttgctattgacatattcatgctctttctatgtctagtggctgacaatgtttgcgtttgttcatttgaataatggtgtgatttctgtttctatattgttagatttgtaatgttttaaatttattcaatttggactggatgtatgtctctagcaatacgaggtactttctaagctattaagggaggggctatatccccatattgagaaaagataatggttgtttaaattttgcatttttttttggcctgcagggatattttgtgttcatgtgtccaaaaataaaataaaaataagacaaatcagcattcttgtgccaaaa

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