LOCUS       XM_045425173            4014 bp    mRNA    linear   PLN 19-APR-2022
DEFINITION  Blastomyces dermatitidis ER-3 RNA interference and silencing
            protein, variant (BDCG_09384), partial mRNA.
ACCESSION   XM_045425173
VERSION     XM_045425173.1
DBLINK      BioProject: PRJNA319322
            BioSample: SAMN02953741
KEYWORDS    RefSeq.
SOURCE      Blastomyces dermatitidis ER-3 (Ajellomyces dermatitidis ER-3)
  ORGANISM  Blastomyces dermatitidis ER-3
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Onygenales; Ajellomycetaceae;
            Blastomyces.
REFERENCE   1  (bases 1 to 4014)
  AUTHORS   Champion,M., Cuomo,C., Ma,L.-J., Henn,M.R., Klein,B., Goldman,B.,
            Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L.,
            Berlin,A.M., Heiman,D.I., Hepburn,T.A., Saif,S., Shea,T.D.,
            Shenoy,N., Sykes,S., Galagan,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center.
  TITLE     The Genome Sequence of Blastomyces dermatitidis strain ER-3
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4014)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 4014)
  AUTHORS   Champion,M., Cuomo,C., Ma,L.-J., Henn,M.R., Klein,B., Goldman,B.,
            Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L.,
            Berlin,A.M., Heiman,D.I., Hepburn,T.A., Saif,S., Shea,T.D.,
            Shenoy,N., Sykes,S., Galagan,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NW_025544788).
            COMPLETENESS: incomplete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..4014
                     /organism="Blastomyces dermatitidis ER-3"
                     /mol_type="mRNA"
                     /strain="ER-3"
                     /db_xref="taxon:559297"
                     /chromosome="Unknown"
     gene            1..>4014
                     /locus_tag="BDCG_09384"
                     /db_xref="GeneID:69030809"
     CDS             1513..4014
                     /locus_tag="BDCG_09384"
                     /codon_start=1
                     /product="RNA interference and silencing protein, variant"
                     /protein_id="XP_045282921.1"
                     /db_xref="GeneID:69030809"
                     /translation="

MYTLKVTRTGTLQVSALVDYLSSTSANAVFGGKEEVIQALNVVMGYYPKDSEHIANVGTNKHFFIKPPDVEKWDLTGGLEVLRGFFGSVRAATARILLNVQISNVAVFAEGPLPRVMMSFFQSYGHSMGKLDRFLKSVRVQLTHMKKVGSDGREVLPIKTILGVATIDDGRGMKNKPRVQRVGAGPKDVTFYKEPNADDEMLGANTSSTAGAYVSVFEFFRDIRKITLENPDLPVVNIGSRERPIYLPPDVCIVLPGQAPNMTLSTTQTQQMIKFAVRRPALNAKSINTKGAQILGASQPANSTLAGFGLAVQPGLITVPGRVLQGPQVRYKSVGRDARPPTNPNSGSWNLQRNQFSVAKPLKNWACLWIQKRDTSLPWPDAETLSSQALDPFIRQLKQLGMTVDQPLIHICPDDFERSIEEHIASVLQFKPSLQLIFFILPVVSSIYSRIKYLCDVKWGVHSICVVAGKFAKERNCQYFSNVALKFNLKLGGTNHTLDPSKLGFISEGKTMVVGLDVTHPSPGSSSNAPSIAAIVASIDQDLTQWPADVRIQPSRQEMVSGLDELLKSRLRLWAKHHRTAYPENILVYRDGVSEGQYNTVLNEELPLLQKACRSLYPAQQTRRGLPRLSIIIVGKRHNTRFFASAPAAADRSFNPRNGTVVDRAVTDARNWDFFLQAHTALHGTARPGHYYLVYDEIFRSSVVKPSLARLTGGIGANVADAVEALTHNMCYLFGRATKSVSVCPPAYYADLVCTRARCYLSRLFEAGSAAGSVAAGSVAGGGRSMSSLEVGLAKLSTAMPQGGEGDGGNDQQEARVSEVRIHELVRDSMFYI"

     misc_feature    <1516..1644
                     /locus_tag="BDCG_09384"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    1684..1836
                     /locus_tag="BDCG_09384"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    1840..2277
                     /locus_tag="BDCG_09384"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1975..1977,2083..2085,2158..2160,2170..2172,
                     2224..2226,2245..2247,2251..2253)
                     /locus_tag="BDCG_09384"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    2422..3795
                     /locus_tag="BDCG_09384"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2854..2856,2866..2868,2902..2913,2920..2922,
                     2947..2949,2956..2958,2968..2970,2980..2982)
                     /locus_tag="BDCG_09384"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(3061..3063,3067..3069,3283..3285,3763..3765)
                     /locus_tag="BDCG_09384"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

caaacacccattatttaaaaaataactcaccgtttcgtggctgctttcaagcttgtcaatcagtagttaaataccctttctttggtaatttctgaaggggaaataattatttctaccgttttacatttatttagctcttccatgcttgttgctgctgctgattgttcttggacatgttcaatttctgcttattccctttttatgtcctccgttttctttccttcattcaagctctacaagggatcttacccccgttctcgttctcgttctcggctacaaccaaatggaacaatctaacatcaaaaggaagaagtctgcatggcaaaatcgtgcattcaggatacgggggactagggaaaattgcgacagccctagagggagggccgttgggaaacaagcaactccattcaatgaaggcttgaagccttgaatcctggaaaccccttcgacatggcctgcatatccccttggtactcccgtttgcacaaacccgaaccgtctgttcattgcgtacgcactcttgtatatatatatttggcggctgttcccgcctcctcgccgtctgcatcatgctatgtcttgctcttcagcactcatctacaagtgtgtgcgtttggttggatacatcatataatgattatcatgaatctctgacggcttatttgataccccttacacttgttttacgtctaccgatcttgaatccctattttctacaattgtgtcgatttactctgtgtgcgtgtgtgtgtgtgtgagagagagtgagagagagagagagagagagatgtcaggaaagccacagaggaaaggtcgaggatcagcgcgagttgaccgcggtggtggtggaggtggccgcgggggccgggatgggggtgggcaaagacatcctatatttggacagactcctgacacccctcgtaataggagagaaggcgtcgcgagtggagacgccgcccaagcaagcgccataagttgtgctgggttctccgatctggaaatcttctcgtaactactattttccatttcctacaaggcgagttgacgggttagagctaatgacatgaatcactcctcagatatcaaagtcatgtcccccaaccaaatagtacggttcagagcgtcgaaaatcatgtcaacactgccgttctagccttgagttcgacatccaaggagcccaaactgccccagcgtccaaccttcggaactcaagggaataaagtcaccctatacgcaaactatttcgagttggccgtgaagcaggatctttctctctaccgctataaaatcattctagatccggatgaaaggggaagactccccatcggcagaaaagcgaaacagatcatccgcctgttcctggatcaggagttttataagctcagcgacaagatcgccagtgactttaagtccaccatcatcagcagcgtggaactcgaacctcttcaaaagttgccttatatagtcacgtaccaagccgaggatgagctagagcccgctccaaatgccagaatgtacactctcaaagttactcgcactggtactctgcaagttagtgcactggtggactacctttcttctaccagtgcaaatgctgtattcggcggcaaggaagaggtcatccaggcactgaacgtcgttatgggatactaccccaaagactcagaacatatcgccaatgtcggtacaaacaagcatttctttataaaaccccctgacgttgaaaaatgggacttgaccggcggactagaggtgctacggggattctttggcagcgtccgtgcagccactgcacgcattcttctgaacgttcaaatcagcaacgttgcggtgtttgcagaaggtccattgcctcgggtgatgatgagtttcttccagagttacggacacagtatgggaaagctggacaggttcctaaaatcggtccgcgtgcagttaacgcatatgaaaaaagttggtagtgatgggcgcgaagtcctacccataaagactattctaggcgtggccactattgatgatggccgcggaatgaaaaacaaaccaagagtgcagagagttggtgccggaccgaaggatgtgacgttttacaaagagcccaatgctgatgatgaaatgttgggcgcaaatacttctagtacagctggcgcctacgtgagcgtatttgaatttttcagggacattcgcaaaattactctggaaaatcccgatcttcccgtcgtcaatatcggaagccgggagcgtccgatatatttgccccctgacgtgtgcattgtattgcctgggcaggctcccaatatgactctaagcacgacccaaacccagcagatgatcaagtttgcggtccgccgccctgcgctaaatgcgaagtcgataaatacaaaaggagcacagatcttaggcgcttctcagcctgcgaactctactttggctggatttggacttgcagtgcagccgggattaattacagtgcctggacgagtcttgcagggcccacaggtcagatataaatcggtagggagggatgctcggccacccacgaatccgaattctggcagctggaatttgcaacgtaatcaattctcagttgcaaaacccctgaagaactgggcatgtctctggattcagaaacgcgatactagtctaccttggccagatgctgaaacgctttcgagccaggcattggatccattcattagacagttaaaacaattgggcatgactgttgaccaacccctgattcacatatgccctgacgactttgaacgatcgatcgaagagcatattgccagtgtgttacaatttaaaccttcgctccaacttattttcttcatcctccctgttgtcagcagcatctacagccgcatcaagtacctctgcgatgtcaaatggggcgtgcatagcatctgcgtcgtcgccggcaaattcgccaaagaaaggaactgccagtacttcagcaacgtcgctctcaaattcaacctcaaactcggcggcaccaaccacactctcgacccgtccaagctcggcttcatatccgagggtaagaccatggtcgtcggcctcgatgtcacccacccgtcccccggctcctcctccaacgcccccagcatcgccgcaatcgtcgcctccatcgaccaagacctcacccaatggcccgcagatgtccgcattcaaccctcccgccaggaaatggtctcggggctcgacgagctcctcaaatcccgcctgcggctctgggccaaacaccaccgcaccgcctacccggaaaacatcctcgtgtaccgcgacggcgtctcagaggggcagtacaacaccgtcctgaacgaggaactgcccctgctccaaaaggcctgccgctccctatacccggcgcagcagacacgcagaggcctcccgcgcctctcgatcatcatcgtcggcaagcggcacaacacgcgcttcttcgcctccgcgcccgccgccgccgaccgctccttcaacccgcgcaacggcaccgtcgtcgaccgcgccgtcaccgacgcccgcaactgggacttcttcctgcaggcccacaccgcgctgcacggcaccgcccgcccgggccactactacctcgtctacgacgagatcttccgctccagcgtcgtcaagccgtccctggccagactgacgggtggcatcggggcgaacgtggcggatgcggtcgaggcgctgactcataatatgtgctatctgttcgggcgcgcgacgaagtcggtgagcgtgtgtccgccggcgtattatgcggatctggtctgtacgagggctaggtgttatttgagtaggttgtttgaggcggggtcggcggcggggtctgtagcagcagggtctgtggcggggggtggtcgatctatgtcgagtttggaggtggggttggcgaagttgtctacggctatgccgcaggggggggagggggatggagggaatgatcagcaggaggctagggtaagtgaggtgaggatccatgagttggtgagggattcgatgttttacatttag

//