LOCUS       XM_039251695            7428 bp    mRNA    linear   MAM 27-JAN-2021
DEFINITION  PREDICTED: Hyaena hyaena protein argonaute-1 (LOC120244909), mRNA.
ACCESSION   XM_039251695
VERSION     XM_039251695.1
DBLINK      BioProject: PRJNA694192
KEYWORDS    RefSeq.
SOURCE      Hyaena hyaena (striped hyena)
  ORGANISM  Hyaena hyaena
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia;
            Hyaenidae; Hyaena.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_024081028.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Hyaena hyaena Annotation Release 100
            Annotation Version          :: 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7428
                     /organism="Hyaena hyaena"
                     /mol_type="mRNA"
                     /isolate="Hyena2069"
                     /db_xref="taxon:95912"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="blood"
                     /dev_stage="adult"
     gene            1..7428
                     /gene="LOC120244909"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 31 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 2 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:120244909"
     CDS             185..2758
                     /gene="LOC120244909"
                     /codon_start=1
                     /product="protein argonaute-1"
                     /protein_id="XP_039107626.1"
                     /db_xref="GeneID:120244909"
                     /translation="

MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    284..676
                     /gene="LOC120244909"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:406799"
     misc_feature    704..856
                     /gene="LOC120244909"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:400854"
     misc_feature    857..1219
                     /gene="LOC120244909"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1013..1015,1058..1060,1100..1102,1112..1114,
                     1166..1168,1187..1189,1193..1195)
                     /gene="LOC120244909"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1352..2629
                     /gene="LOC120244909"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1763..1765,1775..1777,1811..1822,1829..1831,
                     1853..1855,1862..1864,1874..1876,1886..1888)
                     /gene="LOC120244909"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1967..1969,1973..1975,2183..2185,2597..2599)
                     /gene="LOC120244909"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gagctgttgcaggctccgcggcggcggcggcaacggaggctgcgggggcagcggtgcgagcggccgggcttgggggggtgccgagcccggcccggaagcccgagcagctagagtgctgggtacctaggcccctcactctggactccagtctccgggccgcctgacctccgcacgggtatatgggatggaagcgggaccctcgggagcagctgcgggcgcctacctgccccccctgcagcaggtgttccaggcacctcgccggcctggcattggcactgtggggaaaccaatcaagcttctggccaattactttgaggtggatattcctaagattgacgtctaccactacgaggtggatatcaagccggataagtgtcctcgcagagtcaaccgggaagtggtggaatacatggtccagcatttcaagcctcagatctttggtgatcgcaagcctgtgtatgatggaaagaagaacatttacactgtcacagcactgcccattggcaatgaacgggttgactttgaggtgacaatccctggggaagggaaggatcgaatcttcaaggtctccatcaagtggctagctattgtcagctggcgcatgctgcatgaggccttggtcagtggccagatccctgttcccttggagtctgtgcaagccctggatgtggccatgaggcacctggcatccatgaggtacacccccgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttctataaggcgcagccggtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcagcccaagcccctcacagactctcagcgtgtgcgcttcaccaaggagatcaaaggcctgaaggtggaagtgacccactgtggacagatgaagaggaaataccgtgtgtgtaatgttacccgccgccctgccagccatcagacgtttcccttgcagctggagagtggacagactgtggagtgcacagtggcacagtacttcaagcagaaatataaccttcagctcaagtatccccacctgccctgcctgcaagttggccaggaacaaaagcatacctacctgcccctagaggtctgtaacattgtggctgggcagcgctgcattaagaagttgaccgacaaccagacttcgaccatgataaaggctacagctaggtcggccccagacagacaggaggagattagccgcctgatgaagaatgccagctacaacctagatccctacattcaggaatttgggatcaaagtgaaggatgacatgacggaggtgacagggcgagtgctgccggcgcccatcttgcagtacggcggccggaaccgggccattgccacccctaatcagggtgtctgggacatgcgggggaaacagttctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaaacagtgtcgagaagaggtgctcaagaacttcacagaccagctgcggaagatttccaaggatgcagggatgcccatccagggccagccttgcttctgcaaatatgcacagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctaccagggaagacgccagtgtatgctgaagtgaaacgtgttggagatacactcttgggaatggctacacagtgtgtgcaagtgaagaatgtggtcaagacctcgcctcagactctgtccaacctctgcctgaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgccgtctttcaacagccagtgatattcctgggagcagatgttacacaccccccagcaggggatgggaaaaaaccttctatcacagcagtggtaggcagtatggatgcccaccccagccgttactgtgctactgtgcgggtgcagcgaccccggcaagagatcattgaggacttatcctacatggtgcgtgagttgctcatccagttctacaagtccacccgtttcaagcctactcgcatcatcttctaccgagatggggttcccgaaggccagctcccccagatcctccactatgagctactggccattcgtgatgcctgcatcaaactggaaaaggactaccagcctgggatcacttatattgtggtgcagaaacgccatcacacccgccttttttgtgccgacaagaatgagcgaattgggaagagtggtaacatcccagctgggacaactgtggacaccaacatcacccacccatttgagtttgacttctatctttgcagccacgcaggcatccagggcaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcggacgagctacagatcttgacataccaactgtgccacacttacgtacgatgcacacgctccgtctctatcccagcacctgcctactatgcccgcctggtggctttccgggcacgataccacctagtggacaaggagcatgacagtggagaggggagccacatatcggggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagcttttcaagccccaagagctgtgccgcccaaatccagaggaagcaaggaggaggaggaggagggagggtagggaggagctcagaaggccttgtttccttctacaaagtgggcaaaggggtgggggacagggccagtaagccagaccaccagccaggaatttctgatgtccacctcatgacccccactcctcaccccatcttgtcacatctggccctgaccccactggaccaagaggggcagcactggtgcccaccatacacacaggtgtctcttgtgactcacagtgctaaagactcatgcctgacagcttggtaaggtcggctctgcagccccgcggacaaaagctggtaggtttgggtttggtactttagatgggagagtgaggggcttaaaaaagtgggtgggaggagggaaggattttttaggagccttaatcagaaaaggtctagatttgtttaagaggaaaaacaaaaccagacccaggtcaatattttagaatactagatgttttaatgggttgaaaatccagtttgtaggaagatttttaatgctaatggtttcggttgctcctcccccagctgccaccccaccctttcccttatttttttctccactttttctaccccaccttacacctcctccctgacagacatccagcccctagtaagacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctactggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctttcttttgggggatagggtgggggtgggagaggaggatggtggggaagaaatatccctaacccaacaagcctccaaccagagcgccagctattttgcatttgaaggaattgacttccatattcattaagcttttaaaagaccacaacctcaagatggttaaaatccattgacatttgcactttcagacatgacaagtcttggagctgctgagatgactggcccctggcctttccatttacacctcctgttcttcctgtccccccaatttccccacctgcctggatctgaaattactgtcatagcatttctcactcttggcttctttttttcccctgatggtcaagttgcttatgtttcaatatttcttaactggggtgtcttataacaaatgatctttaggtctaaaataagaaaaaaaagagcaaaaactaaatgttatttttataccataacttgagtctattgccaaaatctgaaaatccctcccatgcccaataagtttacatcccagaaacatagagccatcagaaggaactatgtacctgacttgttctttggcctggctaggtaggggatggttatctccctaaggtggaggtcagactctatccttcccctgtgcagataatatctttttcttgctataggctctgtcctctgcactgccctgcactctttcctgcaagttgcatcttccctttctctggactgtcctctgacactttggctcatcccagattccaatgtgtcttgtggacaggctagggaattttgctgctccctattgcttctgtttacacaaatgaattttccccagtttcccactagggcatgtgagtgggtggcatgggcctttgttttgttttgttttgttttgtttttttgttttttgtctccctggatagagattgggtttgctgtcttgcagaactggaaaagtagggggtttctagcttggtgcctactagcattgagataaggccccctctttccttaactgttcattttttcctgtcccactgcttgggatgagttgcagcttcagtgtggaagttcctctttttgaggagcctgagtttgggtttaccccaatctggtgatgaagccatgacactttagacctagctcaggcttggaggccggtctgaatccgggcctgtgcgcttagagctaccatttcccctccccagcagcccttgtacagacccagatttgctatgcaaaacagtctattccaggttctgttctggttggctactttgttcagcaacttcacaaaacgtagcacaaacattgattatggagaaggcatcaggactgttgagtaactcctcctttacttctttcctactggctacagtatgggatgccccatgggcacagcccagctgaagaacagaacggagggctctgggaggaggcagctcactggagagcctacattccttacacaagtgcctaaagagagtgatgccaacactccatctgccctgtccatcgccttcatatgctgtctacttcgtgttcagtcaccctttgggaaggggagctctcttgggacaatgggctctgcatgttctcttcttgggtgcattttggggctgggatcagggcactgttcctggagggtccagtcattcaccagcatttgcaaatatccatagggagctggtggcagccacctactctcaacaacaagtttatgttctctcctttttctctctttgcctcactctctccatttggattttgagctggggcttgcaatgcattttttagctctttggcattgcacatgccgttcaagaagcaagaaaagcagttgggcgatggcaagaaaatgacctcttgctctgattttttttttttaatatctttgagacttgaaaaatactttgaccttgaggattattcttatttgaaagatggtgcatgcagattgagaagtggtgttagcaacaagctttggctttcttggatttggtttaagtggtgcttcttacttgtgctctaaggaagtattggggggaccccagcctcatcctcttggacaggtctcttgctcccttcattttacttttttgctctcttttctgtttctctttccctgaaatccctttccattttttaattcactaagcttgtttgctggcctgcctgcctatgtgatgatgaattctctgcatggctatgataatcccactgttagccagcaaggtcaggcttagcttcttggctacagaaggccaagtatctgttccccaagcccagtaatgtcctctctgggctggactgccatcaaagttactcagcaggcatgcctacttggcatgaaattcagggggcttctgacaacttccacacatgtccactccttggagttggtttctctcattgctttttctaaatctggtcccatttctcttacatgggggcctcccttttctgaagatatcctagagttgagctacttggtttccagggttggagggttaaggggatggacataggggaataagagagtgatgggaagagaatggagagaatttggataaaagatggtaaagagcactgttctttgatcatttttccagtccagtctgacccatttggggttgaggtgctactgctgaactcgggataagcctggagctattgttgttcatgggaatttaggcttagagtaatgttgaagaagaaggtatctaaaagtatgaaacctccctaaaaagctcctggttcccatgtactagatagcgcctctgcggccttctctttggctaaacaacaatgttcttggatagttttgggtgtcttttttgggggagggggagggtccagaatttagtaaacgaggctggcactcaggatgggcagccaaggggacattttgatttcttagctggcccatagattatctatctacaaggcttgtgaggcagtgttttaaacttggcatcacatgtaacaaggaagaatggaagttccttccccttcaggatggaaagtcctctcaaagtagccaaaatgcagttttcgaaactacattgggggaagttattttttatatttaccgggcctaggctaatctaggatggtagctgggatgccttccttcttaaagtctgatcatggcagggatatgcagggcactctttcctatttagccttctaagcagattggggagaaaggattctctggttttctctccccatccttcatccccccttttattaggacttgccttctccctgtgcagggagagaggctaggttggtgctctccccttaatctattcctactgacttagaacctctggctgctgtttgggagcctaagagagggagtgcaggtaatggactcaaaacaaaacagaataaagtgggcaaggcaaagttccttcttgaaaaaggaaaataggaaactctccaaggattgtgcaagtaaagacaatgtgtcgaatgcactgagtcccctggtgtagtagcaataaggaataatgaaatgactttcctgtgcacagtccaacctgactggtgtgtgatgttgcacttagcagccatctggtgggcatgtgtgactactctgggtttcactttagtttctaaactttttatccctttcaagtccagcatggatggggaaatgtccctgaagccccacagctgtgtacttgtttgcatctgtttccctttgagacttgtgtttgtgtcctgctttgagctgtaccttgtccagtccattgtaaaattatcccagcagctgtaatgtacagttccttctaaagcaagcaacagcagcagcacaattctgtgttttataaagacaacagtggcttcta

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