LOCUS       XM_032741195            4348 bp    mRNA    linear   INV 30-AUG-2021
DEFINITION  PREDICTED: Drosophila grimshawi protein argonaute-2 (LOC6569124),
            transcript variant X2, mRNA.
ACCESSION   XM_032741195
VERSION     XM_032741195.2
DBLINK      BioProject: PRJNA728747
KEYWORDS    RefSeq.
SOURCE      Drosophila grimshawi
  ORGANISM  Drosophila grimshawi
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Hawaiian
            Drosophila.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_025062889.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Aug 30, 2021 this sequence version replaced XM_032741195.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Drosophila grimshawi Annotation
                                           Release 103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 9.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4348
                     /organism="Drosophila grimshawi"
                     /mol_type="mRNA"
                     /isolate="15287-2541.00"
                     /db_xref="taxon:7222"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="whole fly"
                     /dev_stage="Adult fly"
     gene            1..4348
                     /gene="LOC6569124"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 EST, 11 long SRA reads, 52
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 32 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:6569124"
     CDS             250..3114
                     /gene="LOC6569124"
                     /codon_start=1
                     /product="protein argonaute-2 isoform X2"
                     /protein_id="XP_032597086.1"
                     /db_xref="GeneID:6569124"
                     /translation="

MYPVGQQSQWTTPSPTRPQSPSQAQTSFDTLTSPPTPGSSVNPTAVTSPSAQNVAAGGATVGGAAAAAAAQAASALGSTGSVTAAIAAAAAASPTTQPDMPVFTCPRRPNLGREGRPIVLRANHFQVTMPRGYVHHYDINIQPDKCPRKVNREIIETMVHAYSKIFGVLKPVFDGRNNLYTRDPLPIGNERLELEVTLPGEGKDRIFRVTIKWQAQVSLFNLEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSSPDGYYHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIDFMCEVLDIRDINEQRKPLTDSQRVKFTKEIKGLKIEITHCGQMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYRMKLRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREINNLVKRADFNNDSYVQEFGLTISNSMMEVRGRVLPPPKLQYGGRVSSGITGQQLFPPQNKVSLASPNQGVWDMRGKQFFTGVEIRIWAIACFAPQRTVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKITFPGLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILVPSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGVSEGQFPHVLQHELTAIREACIKLEPEYRPGITFIVVQKRHHTRLFCAEKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGSSEDRTPGAMARAITVHADTKKVMYFA"

     misc_feature    595..984
                     /gene="LOC6569124"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    1012..1164
                     /gene="LOC6569124"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    1165..1527
                     /gene="LOC6569124"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1321..1323,1366..1368,1408..1410,1420..1422,
                     1474..1476,1495..1497,1501..1503)
                     /gene="LOC6569124"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1663..2985
                     /gene="LOC6569124"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2116..2118,2128..2130,2164..2175,2182..2184,
                     2206..2208,2215..2217,2227..2229,2239..2241)
                     /gene="LOC6569124"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2320..2322,2326..2328,2539..2541,2953..2955)
                     /gene="LOC6569124"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

aaatcaaccaaacgaataaaactactttaaagtgtgataagcaaaaggctgaaatcaaaaaacaaaaaaaaactaagtataataattagtaggaacgaaaagcaaaaacaaagaataaatccaaccaactacaagaacaatcaattacatttaaaacaacaacaaaaatacacccatacacacaaaaagaaaacatagagaaacctttgtatacattcttacatttcttaaaacaaatactagtgcaaaatgtatccagttggacaacagtcacagtggacaaccccctcgcccacgaggcctcagagcccctctcaggcgcagactagcttcgacacgctcacatcaccaccaacacccggttcatcggtaaatcccaccgccgtgaccagtccaagtgctcagaatgttgctgcgggcggtgctactgtgggtggtgcagcagccgctgcagcggctcaggctgcctccgccttgggctcgacgggcagtgtgacggcagcgattgcagcagctgctgcagcatcgccaaccactcaaccggatatgcccgtgtttacgtgcccccgtcgaccgaatctgggccgggagggcagaccgattgtgctgcgtgcgaatcactttcaggtgacaatgccacggggctatgtgcatcactatgacatcaatatacagccggataagtgtccgcgcaaggtgaatcgcgagatcattgagaccatggtgcatgcctatagcaagatctttggagtgctcaagcccgtctttgatgggcgaaataatttgtatacccgggatccgttgcccattggcaatgagcggctggagctggaggtaacgctgcccggcgagggcaaggatcgcatctttcgggtgacgatcaagtggcaggctcaagtctccctcttcaatctggaggaggcgctcgagggacgcacccgtcaaataccctacgatgccatcttggccctcgatgttgtcatgcgccatttgcccagcatgacgtatacgccggtgggacgcagtttctttagctcacccgatggctactatcatccccttggcggtggtcgtgaggtctggttcggtttccatcagagcgtgagaccctcgcaatggaaaatgatgctcaacattgatgtttcggccactgccttctacaaggctcagcccgtcattgattttatgtgcgaggtgctggacattcgcgacatcaacgagcagcgcaagccgctcaccgattcgcagcgcgtcaagttcaccaaggagattaagggactcaagatcgagattacacactgtggccagatgcgtcgcaagtatcgtgtctgcaatgtgaccaggcgaccagctcaaatgcaatccttcccgctgcagctggagaacggtcagaccgtggagtgcaccgtggccaagtactttttggataagtatcgcatgaagttgcgctatccgcatctgccctgcctgcaggtgggtcaggagcacaagcacacctatctgccgctcgaggtgtgcaacattgttgccggccagcgttgcattaaaaagctgaccgatatgcaaacctcaacgatgattaaggccacggcacgctctgctccggatcgtgagcgcgagattaataatctggtgaaacgggctgatttcaataatgattcatatgtgcaagaattcggcctgaccatttccaactcgatgatggaggtgcgtggacgagttctgccgccacccaagcttcaatatgggggacgtgtctcgtcgggcatcacgggacaacagctctttccgccacagaacaaagtgtcgctggcatcgccaaatcagggcgtttgggatatgcgcggcaagcaattcttcaccggtgtcgagatacgcatctgggcaattgcctgctttgcgccgcagcgcacggtgcgcgaggatgcattgcgtaatttcacccagcagctgcaaaagatctccaacgatgccggcatgccaatcattggtcagccgtgcttctgcaaatatgccacaggaccggatcaggtggagccaatgtttcgttatctgaaaatcaccttccccggcctacaactcgtggtcgttgtgctgcctggcaagacgcccgtctatgcggaggtgaagcgtgttggtgacacggtgctgggcatggccacccaatgtgtccaggcgaagaatgtgaacaagacatcgccacagaccctgtccaatctctgtctgaagatcaatgtgaaactgggcggcattaattccatactggtgccatcgatacgacccaaggtcttcaatgagcccgtcatcttcctcggtgcggatgtcacccatccgccagctggtgataataagaagccatcgattgctgctgttgttggttcgatggatgcgcatccatcgcgttatgcggccacggtgcgagtgcaacagcatcgccaggagatcattcaggagctgagcagcatggtgcgtgaattgctcatcatgttctacaaatccaccggtggctataagccacatcgcatcattctctatcgtgatggtgtctctgagggtcaatttccgcatgtgttgcaacatgaactgaccgccatacgcgaggcatgcatcaaattggagccagaatatcggccgggcattaccttcattgtggtgcagaagcgtcatcatacgcgtctcttctgcgcagagaagaaggagcagagcggcaaatcgggcaatattccagctggcaccacagtcgatgtgggcatcacacatcccacggaattcgatttctatttgtgcagccatcagggcatccagggcaccagtcgcccctcgcactaccatgtgctctgggatgacaatcatttcgattccgatgagctgcagtgcctcacgtatcaactgtgccacacttatgtccgttgcacgcgctccgtcagcatcccggcgccggcatattatgcccatttggttgccttccgcgccagataccatctggttgagaaggagcatgattccggcgagggttcacatcagagcggctcctccgaggatcgcacgcccggagcaatggcccgagccataacggttcatgccgacaccaaaaaggtcatgtactttgcctaaaaagtatccaaaagccacaccaaaaacacacaaacaaacaaacaaacagcaaacagcagcagtaacaaacagcaaacaaacaacaaaaaaagaacacttaattttcggagaaatgtattcgaataagcgagtcgccaactcgaaagaaatcgaaaaggataaattggaatatattatacgaagaagaagaagaagacaaagaggaagaaaaaggccaagtcgggaattattagtgattaagttgaaaatgatgatgatgatgatgattatttttaagtttaaaagttaggtcaagtcgcgagttaaaaaaggcaacgccagaacagctcttatggaacagatttatgcattagcttttaaggccaatggataaaacacacacaaacacacacaaaacaagcacacacacaacacaccccaacacacccacacacgccaaattttagaaaattagaaacaaagggaatcgaatgttaaaagcacaagcaggcgcaacaaatgtgaagaaggagaattctcaaacaacaaaatataaataaaaaatcaacaacaagcgtagcgaaacaaaaaactaaagggaacaaaacgaaagtcaagaaaatcaacaacaacaaccgcaagaaagcaaaaaaaaaaaagaaaagcaaacaaacatttacgatgaactttttgtaatagaataaattatatttttacacaacaaaaagaagaaaaaaagtgaagacaagaaatgcaaacaaccaaaggtttttagtatatcaaaacaagaacatttttgctgattaactcaaatacacaacacacacaaaacatacacacacaacaaatacaacaaccaaacaacaactcggaattctctgtactgtgaacgaagaccaccaccaagcttataaaacaagtttaaaaatgacaaaaacaacaacaacaagaaaaaccacaacaatacgacaagcattaaagagtgtaataataattagccatctactaaaaaaacaaaaatacttcaatactacaactcaaaaaaatgtccagaattgtaaaaagctaactttttagtagtcttaagtttggtaaataccaaaaaaaaaaaaaaacaacaaaaaaaaagcaaaaaaagagtaaaacaaaaaacaaaaatgaaaactccaatttcaacaagggacaaacttttggtcaaacaattgctagttatatttatatatacttatatacatgtatgtgtatataatattta

//