LOCUS       XM_028512139            5198 bp    mRNA    linear   MAM 07-SEP-2020
DEFINITION  PREDICTED: Phyllostomus discolor argonaute RISC catalytic component
            3 (AGO3), transcript variant X3, mRNA.
ACCESSION   XM_028512139
VERSION     XM_028512139.2
DBLINK      BioProject: PRJNA524358
KEYWORDS    RefSeq.
SOURCE      Phyllostomus discolor (pale spear-nosed bat)
  ORGANISM  Phyllostomus discolor
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Microchiroptera;
            Phyllostomidae; Phyllostominae; Phyllostomus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_040907.2) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 7, 2020 this sequence version replaced XM_028512139.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Phyllostomus discolor Annotation
                                           Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5198
                     /organism="Phyllostomus discolor"
                     /mol_type="mRNA"
                     /isolate="MPI-MPIP mPhyDis1"
                     /db_xref="taxon:89673"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="muscle"
                     /country="Germany: Munich, Collected from captive colony,
                     LMU"
                     /collection_date="25-Oct-2016"
                     /collected_by="Pedro Rodenas-Cuadrado, Uwe Firzlaff, Sonja
                     Vernes"
     gene            1..5198
                     /gene="AGO3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 5 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 34 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:114496570"
     CDS             159..2039
                     /gene="AGO3"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X3"
                     /protein_id="XP_028367940.1"
                     /db_xref="GeneID:114496570"
                     /translation="

MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPANHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQDEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    159..500
                     /gene="AGO3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(294..296,339..341,381..383,393..395,447..449,
                     468..470,474..476)
                     /gene="AGO3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    633..1910
                     /gene="AGO3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1044..1046,1056..1058,1092..1103,1110..1112,
                     1134..1136,1143..1145,1155..1157,1167..1169)
                     /gene="AGO3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1248..1250,1254..1256,1464..1466,1878..1880)
                     /gene="AGO3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

aaaactaatctgagaagccagttaggaggctttttcaatcactagttcaggtttcagtctacatgttacttccttgagaagcagtttttgacacccttcaccccccaagtctgatttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgacattcataatattgatgagcaaccaagacctctgactgattctcatcgggtaaaattcaccaaagagataaaaggtctgaaggttgaagtgactcattgtggaacaatgagacggaaataccgggtttgtaatgtaacaagaaggcctgccaatcatcaaaccttccctttacagttagaaaatggccaaactgtggagagaacagtagcacagtatttcagagaaaagtatactcttcagctgaagtacccacaccttccctgtctgcaagtggggcaggagcagaaacacacatatctgccactagaagtttgtaatattgtggcagggcagcgatgcatcaagaagctaacagacaatcagacttccactatgatcaaagcaacagcaagatctgcaccagatagacaagacgaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcaatttaaagttcgagatgaaatggcccatgtgaccggacgcgtacttccagctcctatgctccagtacggaggacggaatcggacagtagcaacaccaagccatggagtatgggacatgcgagggaaacagttccacacaggggttgaaatcaaaatgtgggctatagcttgttttgccacacagaggcagtgcagggaagaaatattgaagggtttcacagaccagctgcggaagatttccaaggatgcggggatgcccatccagggccagccttgcttctgcaaatacgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgccagggaagacgccagtgtatgcggaggtgaaacgtgtaggagatacacttttgggtatggctacacagtgtgttcaagtaaagaatgtaataaaaacatcccctcaaactctgtcaaacctgtgcctaaagataaatgttaaactcggagggatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatatttttgggagcagatgtcactcatccaccagctggtgatgggaagaagccttctattgctgctgttgtagggagtatggatgcccacccaagcagatactgtgctacagtaagagttcagagaccccgacaggagatcatccaggacttggcctccatggtccgagaacttctcattcaattttataagtcaacgcggttcaaacctactcgaatcatcttctatcgggatggtgtttcagagggacagtttaggcaggtattatattatgaactactagcaattcgagaagcctgcatcagtttggaaaaagactatcaacctggaataacctacattgtagttcagaagagacatcacactcggttattttgtgctgataggacagaaagggttggaagaagtggcaatatcccagctggaacaacggttgacacagacattacacacccatatgagtttgatttttacctctgtagccacgcaggaatacagggtaccagccgtccttcacactatcatgttttatgggatgataactgctttactgcagatgaacttcagctgctaacttaccagctctgccacacttacgtgcgctgtacacgttctgtttctatacctgcaccagcgtattatgctcacctggtggcattcagagccagatatcatctcgtagacaaggaacatgacagtgctgaaggaagtcacgtttcaggacagagcaatggacgcgatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtactttgcttaaaaaatccgagagtattctctgaaaggaagaactgaaagatgaattgacatacaacgtatgtttccatggaatctgttgagtggggatgcctccagccatacagaaaccaacactgtggggaccagggtctgatttttatgttgatacaaggaagattgtttacttcatcaaggaacacagcaccattatgcaatatgaaaccagccaactgcttttctgtgcggtctcctgtaggaagtatcgccattgttttgttttcactttctatagtctaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaagtaaagaaaaggtaaatgataatttaaaaaaaacacacctgtatgaataatcagtgattgttcataattatgtgtgtgaaaaaattaatgtgcattcatgtattcttgtaaaaagtatctgtgtatactttaagtgtatacatgtatacttcatatacatatatatctggatctaccttgataatagatatatatgttctttgtatatattttataattcattccattgggaaatttctttcccttttattgtctgctcaccaccacttttatttctcactctacctcccctgcctcatcacctacgttttttttccttaatgctaccagtgacattcaaatgtctgtgtatctgattcatttgaatatgaagcatcacaaagtagacttttattttgcacacccactcctctctcgtctcatacacaatattaagtcctcaactcttgatattactttcttgagaagcagttattttatgtgtgtgtgtgtgtgtgtgtgtgtgtatgtttttgtgagagtctgcgtctgccacctcctgctctgaatttacatttgccacttgtgcaaggtgtgcataagcagtagcaacctattcttttttttttagtgagtttgttaaagctgctataaatataaaatcttgtcagaactataactctctctctgtaagtgatatgtattctaaagccttctgtttctgtgggttatacatggaaatcccttaaaggatttttttaaagggtaaatattttaaatgattagaactctgtagggttgagacctctgaaattggagtgagagaaagaaggagttgttcgagttaaattttttttttgctagtttacttgctgcctctcataccttaatgtgattttcatatatatatttttatatatatgcgtgtgtatatataaatatatatgtatgtattttgaagtatagcttccttttcttttatatttattagagtagtgctttaatgattatagaactgtattggcaacatgttttatagaaatataatcatgtttattttaagaactgaccacctgtttttgctattttttcgtgcaataagccgttagaaaggaaagctgtgtctgtctgacactctgccccagacagtgttggagcaggcacctccgcagttttgaaagagcagagtgatacagccttaatttcagaaggaaagtttttctttattttcaaatctaaagcaagtctgaccttgaatattaaaaataaagttgaactttgacctaaatgatcatgaatagattaaaatttagaagatatttaaattctttgaaaatgaatcatgtttatggaagaatcatactggttaggggcccattttcatttattaagatgagtcaggaaaatgtaatattttaaaaaatatttttgccaatttactaccagtgtaactttccttttaaaattagggttatggtgacaaaggaagttaggacttcagttattttaaatgagttaataactgaaatgtgggggaaagtattgcaaaatttgtttgatggatttcactttaagatattaaaaagtactataaagctgtcaaaaccaagttcaccagtaacattggattcaggggaactttgcactttgtaactcacgaaaattgcattttactcttcttttgcactggttcagagtataactattacagattgtttccagggggcattgtcgttaacctttccaaatgtcatctgttcatgaaaatgaatgggttagtttagctctgtagtttctctctcacctgtaacccactcttaactgccagttactgtattttgagcctaaaatctgagcccatgtcctccaacagttatgaaatcttttgtccctctctcagaaaactaagaaagtactgtattttgtatgtttattatattggagtgtctgaaatgcaatttacaacactgtttcaaagctctttacatgaggtaatatttgtatagtacagtatatacattttttctctcaaccctacccccttctcctccaaaaaatcctataaagcatgtattttttttttacattgaaaattcactgaatatagtagtcagcaacatgagcaagggaagaaaattgtgtgttctaggtggtaaaaactttgtttgctgtgtgcttgctcagtgtgagtaaaacatctccctttatcagagagagttacgcagattcatgtgggaaactttagggcccagtgaagaactgtagatacccctttgctatttactgctttacctaattttttttttttttttttcagttatttcgtgtcacatgcactagagtgcagcccataatttaaatgtatttgggaggacttttacaaaggaaaacaaatattttttaaatacaaagctttacctttgaagtgagttcttttttacggtttcttacagtttcaaacattattagtttagtttaaagttggttaacttgaaagagtatgtagagtatatttctattttgcttactaacaaattagtgtgtcacacttacatagaagaaacattgtacttagaattttaagataaaagagtaagaggcaagtactttttgaattttgttttaattattattgcacttctggtgtagaattcctgaccatttttattttttaaaaagatcgttctgaatgtaatggccatgaaactcaatagcgacttttctgttctgccctcactcactaactatataatcaatgctaagttttggtctgctgttgtctgtgatgtacagtatcagagtgactttaaaatgtcagttctagcaactggtataattgatgttcatg

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