LOCUS       XM_024643007            2901 bp    mRNA    linear   INV 10-APR-2018
DEFINITION  Strongyloides ratti Protein argonaute-4 (SRAE_X000201400), partial
            mRNA.
ACCESSION   XM_024643007
VERSION     XM_024643007.1
DBLINK      BioProject: PRJNA304930
            BioSample: SAMEA1682816
KEYWORDS    RefSeq.
SOURCE      Strongyloides ratti
  ORGANISM  Strongyloides ratti
            Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
            Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
            Strongyloides.
REFERENCE   1  (bases 1 to 2901)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2018) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   2
  AUTHORS   Aslett,A.Martin.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-SEP-2014) WTSI, Pathogen Informatics, Wellcome Trust
            Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge
            Cambridgeshire. CB10 1SA, United Kingdom
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NW_020171512).
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..2901
                     /organism="Strongyloides ratti"
                     /mol_type="mRNA"
                     /strain="ED321 Heterogonic"
                     /db_xref="taxon:34506"
                     /chromosome="X"
                     /map="unlocalized"
     gene            <1..>2901
                     /locus_tag="SRAE_X000201400"
                     /db_xref="GeneID:36385086"
     CDS             1..2901
                     /locus_tag="SRAE_X000201400"
                     /codon_start=1
                     /product="Protein argonaute-4"
                     /protein_id="XP_024499485.1"
                     /db_xref="GeneID:36385086"
                     /translation="

MAATGIDHQQNMNNMFDALSFDDNGTIQMPNSMTGFLGLQDANHHYIQNDFFTTQITNLPQDLSVLHTGSQSIMNNEGNMSDNHSLLSFAPGVPMMSTISDDQQALIPSQQLSFTFPIPKRPDHGQQGREIALKANHFKVSIPGGNVQYYQVDVSPEKCPRKVNRDVIKALISSYPNVFVNTKLVYDGKKNMYTRELLPIGTDRNEFEVNLSGDSNQERKFTVGIRYQATVSLQRLEDAMAGIIHSIPADAVQAMDVILRHLPSTQYTPVGRSFFSSPHTTKPQHSGQHHHGQDYGKLGGGREVWFGFHQSVRPSEWRMMLNIDVSATAFYRRMSVLEFLAEVLEQPVSTFAERRSLSDAQRVKFTKEMRGLKIEITHCGQMRRKYRVCNVTRRPAQSQTFPLLNDNGMTTDCTVAKYFLDKYNMQLKYPYLPCLQVGQEHKNIYLPLEVCDIVSGQRCIKKLTDTQTSTMIKATARSAPEREREITNLVQKADFTSDPYAAEFGISITPEMTEVKGRVLPAPKLLYGGRTKTTALPNQGVWDMRGKQFHTGIEVKMWAIACFAQQTHVKEHDLRSFTGNLQRISSDAGMPIIGQPCFCKYAVGVDQVEPMFQYLKNTYPGLQLVVVVLPGKTPVYAEVKRVGDTVLGIATQCVQAKNVIKTTPQTLSNLCLKMNVKLGGVNSILLPSVRPAVFNEPVIFLGADITHPPAGDSRKPSIAAVVGSMDAHPSRYAATVRVQQHRHEIITDLAYMVRELLVQFYRNTHFKPTKIVLYRDGVSEGQFLNVLQYELRAIREACMTLERGYQPGITFIAVQKRHHTRLFACDRRDQVGKAQNIPPGTTVDAGITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNNLKADELQQLTYQMCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDREHDSGEGSQPSGTSEDTTLSNLARAVQVHPDANNVMYFA"

     misc_feature    529..777
                     /locus_tag="SRAE_X000201400"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    805..996
                     /locus_tag="SRAE_X000201400"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    1000..1362
                     /locus_tag="SRAE_X000201400"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1156..1158,1201..1203,1243..1245,1255..1257,
                     1309..1311,1330..1332,1336..1338)
                     /locus_tag="SRAE_X000201400"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1495..2772
                     /locus_tag="SRAE_X000201400"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1906..1908,1918..1920,1954..1965,1972..1974,
                     1996..1998,2005..2007,2017..2019,2029..2031)
                     /locus_tag="SRAE_X000201400"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2110..2112,2116..2118,2326..2328,2740..2742)
                     /locus_tag="SRAE_X000201400"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

atggctgcaactggcattgatcatcaacaaaatatgaataacatgtttgatgcgttgagttttgatgataacggaactatacaaatgccaaattctatgactggatttttgggacttcaagatgctaatcatcattatatccagaatgatttttttacaactcaaataacaaacctacctcaagatttgtcggtgttgcatactggatcccaaagtattatgaacaatgaagggaatatgagcgacaatcactcattactctcatttgcacctggagtcccaatgatgagtactataagcgacgatcaacaagcgttgataccaagtcaacagttatcattcacttttcctatcccaaaacgtcctgatcatggccagcaaggaagagaaatagccttgaaggcaaatcattttaaggtatcaattccaggaggtaatgtacaatattatcaagtagatgtatctccagagaaatgtccaagaaaagtaaaccgtgacgtaataaaagctttaatttcttcttatccaaatgttttcgttaatacaaaattagtttatgatggtaaaaagaatatgtatacaagagagttattaccaataggtactgatagaaatgaatttgaagtcaatttatctggagattcaaatcaagaaagaaaatttactgttggaatacgttatcaagcaactgtttcattacaacgtcttgaagatgcaatggctggaattattcatagtattcctgctgatgctgtacaagctatggatgttattttaaggcatttaccatcaacacaatatactcctgttggaagatcatttttctcatcaccacatacaacaaaacctcaacatagtggacaacatcatcatggacaagattatggaaaactgggaggtgggcgagaggtttggtttggtttccatcaatctgtaaggccatcagaatggcgcatgatgttaaatattgatgtctcagctacagcattttatcgtagaatgtctgtattagaatttttagctgaagtattggaacaacctgtctcaacatttgctgaaagacgttccttatctgatgctcaaagagttaaatttacaaaagaaatgagaggattaaaaattgaaataactcattgcggacaaatgcgtagaaaatatagagtttgcaatgtcacgagaagaccggctcagtctcaaacattcccacttcttaatgacaatggaatgactactgattgtactgttgcaaaatatttccttgacaaatataatatgcaattaaaatacccttacttaccatgtttacaagttggtcaagaacataaaaatatatacctgccattagaagtttgtgatattgtttcaggacaaagatgcattaaaaaattaactgatactcaaacttcaacaatgattaaagcaacagcacgaagtgctcctgaaagagaacgtgaaatcacaaatttagttcaaaaagcagattttacaagtgatccatatgctgctgaatttggaatttctataacacctgaaatgactgaagttaaaggtcgcgttcttccagcaccaaaacttctttatggtgggcgtactaaaacaacagccttacctaatcaaggagtttgggatatgagaggaaaacaatttcatacaggaattgaagttaaaatgtgggctatagcatgttttgctcaacaaactcatgtcaaagaacacgatcttagaagttttacaggaaatcttcaacgcatttcttctgatgctggtatgccaataattggacaaccatgcttctgtaaatatgcagttggcgttgatcaagttgagccaatgtttcaatacttaaaaaatacttatcctggtcttcaattagttgttgttgttttaccaggaaaaacaccagtttatgcggaagttaaacgtgttggtgatactgtattaggtattgcaacacaatgtgttcaagctaaaaatgttattaaaacaacaccacaaacactttcaaatttatgtttaaaaatgaatgttaaattaggtggtgttaattcaattttacttccttcagttagaccagctgtttttaatgaacctgtaatatttttaggtgctgatataacacatccaccagcaggtgattctagaaaaccatcaattgctgcagttgttggatcaatggatgctcatccatcacgttatgctgctacagttcgtgttcaacaacatagacatgaaataataactgatcttgcctatatggttagagaacttcttgttcaattttatagaaatactcattttaaaccaacaaaaattgtactttaccgtgatggtgtttctgaaggtcaatttttaaatgttcttcaatatgaattaagagcaatacgtgaagcttgcatgacattagaaagaggatatcaacctggtattacttttattgctgttcaaaaacgtcatcatacaagactttttgcttgtgatagaagagatcaagttggtaaagctcaaaacattccaccaggtacaactgttgatgctggtattactcatccaacagaatttgatttttacctttgttcacatgcaggaattcaaggtacctcacgtccttcacattaccatgtactttgggatgataataatcttaaggctgatgaattacagcaattgacttatcaaatgtgtcatacttatgttcgttgtacaagatcagtatcaattccagctcctgcttattatgcacatcttgtagctttccgtgctcgttatcatttagttgatcgtgaacatgattctggcgaaggttcacaaccatctggaacttcagaagatacaacattatcaaacttggctcgtgctgttcaagttcatcctgatgccaataacgttatgtattttgcctaa

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