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2020-04-07 22:34:14, GGRNA.v2 : RefSeq release 99 (Mar, 2020)

LOCUS       XM_022555525           11827 bp    mRNA    linear   MAM 16-SEP-2019
DEFINITION  PREDICTED: Delphinapterus leucas argonaute RISC catalytic component
            2 (AGO2), transcript variant X7, mRNA.
ACCESSION   XM_022555525
VERSION     XM_022555525.2
DBLINK      BioProject: PRJNA407951
KEYWORDS    RefSeq.
SOURCE      Delphinapterus leucas (beluga whale)
  ORGANISM  Delphinapterus leucas
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Cetacea;
            Odontoceti; Monodontidae; Delphinapterus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_022098049.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 16, 2019 this sequence version replaced XM_022555525.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Delphinapterus leucas Annotation
                                           Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11827
                     /organism="Delphinapterus leucas"
                     /mol_type="mRNA"
                     /isolate="GAN/ISIS: 26980492/103006"
                     /db_xref="taxon:9749"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="blood"
                     /dev_stage="adult"
     gene            1..11827
                     /gene="AGO2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 4 mRNAs, 8 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 5 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:111165164"
     CDS             205..2289
                     /gene="AGO2"
                     /codon_start=1
                     /product="protein argonaute-2 isoform X7"
                     /protein_id="XP_022411233.1"
                     /db_xref="GeneID:111165164"
                     /translation="
MRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA"
     misc_feature    241..387
                     /gene="AGO2"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:337161"
     misc_feature    388..750
                     /gene="AGO2"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(544..546,589..591,631..633,643..645,697..699,
                     718..720,724..726)
                     /gene="AGO2"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    883..2160
                     /gene="AGO2"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1294..1296,1306..1308,1342..1353,1360..1362,
                     1384..1386,1393..1395,1405..1407,1417..1419)
                     /gene="AGO2"
                     /note="5' RNA guide strand anchoring site; other site"
                     /db_xref="CDD:240015"
     misc_feature    order(1498..1500,1504..1506,1714..1716,2128..2130)
                     /gene="AGO2"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      
tgaattggatatcaagccagagaaatgcccaagaagagttaacaggtggagctggaggtcacgttgccaggagaagggaaggaccgcatcttcaaggtgtccatcaagtgggtgtcctgcgtcagcttacaggcattacacgatgcactttcggggcggctgcccagcgtccccttcgagacgatccaagccctggacgtggttatgaggcatctgccgtccatgaggtacacccccgtgggccgctccttcttcacggcgtccgagggctgctccaacccgctgggcgggggacgagaggtgtggtttggcttccatcagtccgtccggccttctctttggaagatgatgctgaatatcgacgtctcggcaacagcgttttataaggcacagccagtaatcgagtttgtgtgtgaagttttggattttaaaagtattgaagaacaacaaaaacctctgacagattcccaaagggtcaagtttaccaaagaaatcaaaggtctaaaggtggagataacgcactgcgggcagatgaagaggaagtaccgcgtctgcaacgtgacccggcggcccgccagccaccaaacgttcccgctgcagcaggagagcgggcagacggtggagtgcacggtggcccagtactttaaggataggcacaagctggttctgcgctaccctcacctcccatgtttacaagtcggacaggagcagaaacacacctaccttcccctagaggtctgtaacatagtggcgggacagagatgtataaaaaagctgaccgacaatcagacctcaaccatgatcagagcgactgccaggtcagcccccgatcggcaggaagagattagcaaattgatgagaagtgccagttttaacacagatccgtatgttcgtgagtttggaatcatggtcaaagacgagatgaccgatgtgaccgggcgggtcctccagccgccctccatcctctacgggggccggaataaagcgattgccacccctgtccagggcgtttgggacatgaggaacaagcagttccacacgggcattgagatcaaggtgtgggccattgcgtgcttcgccccccagcgccagtgcacggaggtccacctcaagtccttcacggagcagctcagaaagatctcgagagacgcaggaatgccgatccagggccagccgtgcttctgtaaatacgcccagggcgcagacagtgtggagcccatgttcaggcacctgaagaacacgtacgccggcctgcagctggtggtggtcatcctgcccggaaaaacgcccgtctacgccgaggtcaagcgtgtaggagacacggtgctggggatggccacgcagtgcgtgcagatgaagaacgtgcagaggaccacgccgcagaccctgtccaacctctgcctgaagatcaacgtcaaactgggcggcgtgaacaacatcctgctgccccaggggaggcctccggtgttccagcagcccgtcatctttctgggggcggatgtcacacacccacctgccggggacgggaagaagccctccatcgccgccgtcgtgggcagcatggacgcccacccgaaccgctactgcgccaccgtgcgcgtccagcagcaccggcaggagatcatccaggacctggcggccatggtgcgcgagctgctcatccagttctacaagtccacacgcttcaagcccacccgcatcatcttctaccgagacggcgtctccgaggggcagttccagcaggttcttcaccacgagttactggctatccgagaggcatgcattaagctagaaaaagactaccagccggggatcacgttcatagtggtccagaagaggcaccacactcggctcttctgcaccgacaagaacgagcgggtcgggaagagcggaaacattccagcagggacgaccgtggacacgaaaatcacccacccgaccgagtttgacttctacctgtgtagtcatgctggcatccagggaacaagcaggccttcccactatcacgtgctttgggatgacaatcgtttctcttccgatgagctgcagattctcacctaccagctgtgtcacacctacgtgcgctgcacgcgctccgtgtccatcccggcgccagcatactatgctcacctggtggccttccgggccaggtaccacctggtggataaagaacacgatagtgctgaaggaagccatacctccgggcagagtaacggacgagaccaccaggcgttggcaaaggcagtccaggtccatcaggacacgctgcgcaccatgtactttgcttgacatgttttagtgtttacgattgtgtaccgagttggattcacatgagaccagctacactcagaccaacaaatgcccagcccttccgtgacagccagcatcgaacatgaaacgccattgattttagtagattctccactttccagaatgccttccgtcccagatttcaaacttggattttgaactgcagacctgtatgagaccccattgtcgtaggaaatatggtttgccaaaatcttataagctgcttatgaaaatagagtcccgtgtttcctaaaaatctcctaaaaccagtctatgaactcagggctttaaaacatttttaatttatttggtcgttcgatttacttgtttttaacacatgattctatatgaaattgatgggctcaaactagctgtgaacgttctgtgagagtgaaagcaacataaaacacattgtggttttaaagccttgaacattctgatgctgtcactaaagtttatttcagagtgacacctgtgtgctcctgaccagctgtccgggatccgagggcaggggccaggcgaggcgccctggtgtctctcgttctgccactgcccgcctttcactcagcccgaaggaaggaggggtggcagaaggtgggccgtgtgtgtttacaacatttataggtccagagggattggcagacaagtgccattttaataaaaatttatttaaaaaaagaaaaaagacaatatgccgacagtctaatcataagatttgtcctgtaggactgtgacgtttatcttccaaagtttctgaagaatacgggtctgtggtgataaatacagtacaatcctttttcactgttatgtctttaatgtaagagaaaagtatatatatctggtttgcagtattaatgtgatagatagatgctgtttttcattttactgactacggggtgcttttgtgatctgtttagcatatcaagagtgttttggagcctggagcctggaccacccttgtggtttctcagtgcttaagtacaggagtatgcaattgactcagtgcccgcggcccaccccctcgtgtagaccgcgcagcctggaccctcaggaggacggagtgtgcttccagcagtcactcccctccccgcctcatccccgtgtgtcgctcagccaattaagcacaaatggaatgtatgtatccttccgctcctgggaatgagtctgcgtgtcggcgtgcacttctctctgcgtgtggtttgttagacaagcgtcataggatctatgcactgaaacacagagaaggctgtcggtggtggcgctctgcgggctgcgaggcccgcgttccgcgaaggagcccagccctcgggaggatggctgatggcgaagccagcagcagaggcagacccttctgctaggatttgcgtgctgggccccggacgtgggtttgccaatctagaatccattgcactaagaatgataccgtggacagctcgacagggctaacagcagagagctccgtttgtgctcagtgggcttttggtccttgtaggcggttttctgagaatccaatccacgttcagtacagagattctaggaaggagatgagcctttccctagtgctgcttcgtgctctgtaggtttcctctggccctgctgacggccctcccatcccggcctgacattacctctggcactgtggtggagtgagggtcccaaccagggtgcctcgtgctggggtcagcgcccgcctcggtcttgtgtgagggctccgcgggggcagggaagcgctgtcatggacactcggcctggattttggcggcaacgacaaaggggtgactattatttgtgacaatatatactcaagagtggtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcgtgcatgtatgcgcgcgcgcgtgtgcgtgcatgtgggtgtctaataatggcattagtctcttcttgctgtatcatttttttttttatgtctttttaaatgacagaagcctctgctctaaaaatgttgcaattccctgtcattttgttagcaagtggcactttctctcgttcagaaggataccagtacactcttggcttaagttaccgggagcattcaagctaaggagggaaccttttcactaatacacttttaaaatctgaacttaggttagttttcagtcatttttaggatcatctagaaccgtgtgtctcgaaggtatgtttctaccacttgcaacaggatctcggtggtcggggcattggccgtaaaaacgctgtgactcctgtgctcgctgcggcctctggggtggcggctgggcatctgcgttttacaccatcagctgggggtccagggctgcctggagtccgagaacctctaatctagagccttctggagagtgtgctccctcaagcactgagggcccagcagggagggactccccagcaatgcagggaaacgttttctaaacgaatacactgggcaggatcacaggctggcagaaaatgagacctaaatttttaaaaaatcgttttgaaggaaaagttttctttctagagggccaaagtactttgagaaaagtacttgttacagccctgcgcttgttttataaaacttttactacttaaaagcattcataaaccaaatgtctccagctgggttagctgcatacctttgtacatgtctgatggttcagaattcaaatggctgtagttacaatttctcaggtaaagaactgttttcccaaatttctaccaatcccccccccccgccccattattaggataaattttgagacagcgtaaaacctcaaggtgcagtagaataagtccaagccctgttcacgtggaagccaagagaggccctgcccgttctgtgtgggtcacgcccgcccagggcaacctcgtggccgcccgagaagggctccgggcacctccggcctctgcctgcgtttgacgggtttcctgaggcctgtgcggggctgtacaaattgcagaggtgcccactcgccggctttgcctgaccccactaagtaaggtgtgccttgctttaagcaaactgaatgtgaaaattatgaagtagaaatctggattaatttcaaagaaaaactgggatttatctcttcagaagaggtctcccaattagacccttatcctggtactcttcctaatatattttaaactattcaccgtaagaaaagttaacatattcccatcccttcaccacttcctattacgttcgacaagctctcaccctaatagctaagcgatgaaagaaaccccggggagctgctccaagtcgccgttttgtaggagagccctttggccctgctgagattccatcctgctgtttgtgtacttagtataataagctcagatgttcctagttcagataaatgttgtaaagctgggcatacctatacttttagaaagggattgttttattttggttttggttttctgttttgagaagacttcacatatacacttgatactacattttagggcctgctttctcttttcaagattgtgttgctttttggtagtgtcctcacactcccgtgcatgaatgtttgcactctagaaccacgagcgatccctggccactgcgccggcttccccaggagggacttgttggaagtggagtgatttccgtgctgtgtgagtctggccgtaagcagtgctgttgtgatgtttaccccggcgtgtgctcattagaagagacagttgaagttcaattcctgcagcagggttgtgggcgggtgggtgtcgatgttatattgtttgttatttttattgttgttaaatgcaaatgttgctatttattgtttcctttctgctctggtttcatttggctgatacggatattccagtgcatgtggtacctgatgaatatgatagaaattcttttccccaacttttataaattacctaatgtttacctgcaagtttgctggatgatttatttttgaaagccacaagtgtaatttttctggatgaattgtttttcttagatatgcggcaatgtaatttaacattgatctgcagggtgacttaaattttatttttacaaggcagtttttcagtcagattatatatttgatacaatatgttaagggtaggccagccaagcgttgtgcagttgggacaccagactgtctcgaggaggcctctggaggctggggcggcttctcttggttgcttggcgtcgtggaagcactaggctgtttcatggagccacccgtcaggatctggatggagtccttgagtgggactttgatctgttgggcagttcaaaggatttttcatgggcattttcctacacctaaggcagttccattaggaggagctttagacgttgacataatccagacagtggacaatcccagtggcccagacaagccatagaaatttccctgtgacctctctttaactcatctctcaaacgctcatgagaaaaggaatgtacaatgaatagaaacttcctcagtgttcatacgcctcactttcagaatgcaaatactttgtattttaagccctcccccaaaggaaccaagaatattctctctagctgccgtgccagcagtttcggctgctgtgacgtttctcagtgtagacacagtgcacgtgtgacttcgtaatagggctgtccgtgttacacacacatgctgacttcttttgtaaggaaaattttcaactcgaaataattgcactgattttttgacagcttcctttttattatgtccaactttgcatctgctgtacttgtttgaaatgattgtaaatagatttaggatagcagaaatgatgtaatacaatgcgttgctttgttttagtgatcctgccacgtttttcagtattatgtgttagagccgtgtgggctggccgctgcccttccccctctacagccatgtgtatgtgtgtgtgtgttgaccattcatgaaggacagattagcctcgttgctgtctttttctggaaggaagtttgcagtgtattggaagaagagtgtgctctctccttgcggtctgagatttaattccaagaggattaattgtaaatcctttgaatgcttctggtctgtttaattcctcgttatttgccatgactccctaaagcatttgctgctagctccctccagcatttgacagcttggataggaagcatctgaacggccaatgttactagagagtcagggcctcccttgcttctctttggtcacccgtcatttgaaagccatgaggtcgctgttatgtcagaactgtcatttgtggcttaacccataggtgccaggcagacctgaaaggcaggctgttcctttaggcctcgtgatttggccagatgagaagaagtgtgtgctccagtccacagtgtgtaagttctgtctgtgatcaggttacacagtatcagacacacaaaggagcttttacacccaaaccagccatctgagtgtgtgttagtgtcacgtcgatgccacctcggtgccctcacttagtgcttttttggatcttttgccattttattgtctaaagtgaatgtattggcttagccatatcactacagaaggtggtttctaataccttttagtttaaaaataaataaataaacgcagataaaggctacctctgaattctcaatagattcatgtttgcttttaagtgtagctatccacactgaaaatagccaaaatgttgcctgaatcaactgaattgtgaacatctctctgttcagttctggcttgaaaatttgtgtgccatactgtgacccacgggcagtcccctcctccctctctgggtgtccagggtggaccagggactcctcagggctgcccggctccgagatgttaggactctcagtggccagcaggaaggaaacacaagggcctttctgcaccgtcctcaggtgcagggccgtgtgtggtgggacctggaagcgacccgctgtcctggcttttcactttcctgtttgacataaggaagcactttttttttctgctttacttatgaatgggttgaaagtgtctccttctactctcttctccctttttgtacactctgtaaaaatcacaaaggtgcttaaacaccgactcttgtgcaaatagtacttcagtagctgcatggtttcaaaatgcagtgcagatgtcgtcgacctttgacttgggagccttgagttactaatgactctatacttgagagtgagctaaggtttgaaagcaaaatgttctgttcaaatccaaggccctttgcttgaaaggagcacagggtccagggcggcagcgtcctgaagtaggggttcctgctgctggcgccctggaccaggatgccagcctgcgggaagactggcctgggagagctcggcatcacgtgtcatgaaccactttgctgtcagaaatctcatctgctcgcacgctgctgtgggttggtcagtgtcgcccccctgctccttcgcgtcttttctttaggttcctcatgttctctcgtcttcagaaggtgagcttttgctcccgatcacttgcgctggtttgctcctgagttctggagggacagttgggcggtgttgcagttgcaggcgtctgggtgtgaggaggcggctccgctctcttctgggcgctcatcagaccttgactttggcccagagagtttccaggtgcaccattacgaggaagtccttgccttcaacgctgcatgctgcgctttaattccgaaagcgccaagtgtcctttgcagtctaagaatgtgtaattctgcagtcgtgctgtcctatagacacagaccaccctgagaagcgtggacactggggagcgtccgctacctctgctggcctgcttctggggttgctgggctccgctgaagtggcctcattttcagccagaaacccatacagggctttttgggggccgctgcgcggcggccggctcctcgctttagtgatgtcagccgttgactcagatctcccacctgctttctgcactcatgtccccagcgtcccgacgtgggcctcccccggcatctttgcgttcacgaaagataattaaagatgagggaactgaagattactggtgcttttgttaatacttttctgtcttattggttgatgtgaaaaattcaggtgcgttagatctttaaacgcccttggtggtgtgactgtaggcttgggtcctcacctcaccccccttctttaggcggttggaggaggctgaatgatctcctagttacaacttccttggcctcaagtagttcagagttaaagctacaacaccaaatattgactctccaggagctcgatgttcaggccaacctcatttggtacttctggaatcttcaaggtcctcaaaaccatgagttgatgctaggaatgtgccccctcgccgcccaccaccacctaccgggctgggggtggggggtgcgatgcgggtgggctgcccggccccgccggacggaactgggaggcccagggctcctctggactctggagatgctgggaacgatgctggggggtgggagagggcagcccctctgacccaaggggcaggcggtgcccaggcctcccctggtctccagaggccaggggtgccagactgaatgtgttctggagaccccgtctcagcctccgtgcctttcaagtccagtcctcagtgtcctttcgaaaccacggtgtggctgcgttgttgggaaggaagcctggcccggcgcacgctcaggcaccggcgctctgccttggaagccgcaccgctcctcggcttctgggcactggctcctgcgggaaatcgctgggttctggccgcgtggctcctcccaggcccagagcacgtccgtccacaggacccctctcctagtcgggtgctgaccgtgaccgccggcaaacctggggggtttgttctcaaggtcactcaatgagaatgttgagcgtaatggaactagattgttttcaaaaaggaattggaattggagtcgtgtctttgtagaatgcgtgggaagtcctcagatgtcaggtgccatttcagttgttggagtgccccgcgttgttgttgttttgtgacgtgctgggaaactgcttcctcgcgagtggtgtcacctggagctgtgcacgtaggactcgggttttgacgtctcgaagatgcaggttttagctctgacttttccaagccaggtattgagttgagcagttttcttggccgacggtctagttaaaagccactcagaattctctgtcagtggatggttttaagcgggggaaataacccaatgttacttattttaaactgtctagaaaagccttcaaggtggcagctcttggcccttctgtctccccctatatcctctgttctgaaaggcagaggcaccaggcaccgggggggctgcgggcggctttggggggccgtaacacagcgatgacgtgggctcctcttcaaagccaaacagacacgcggctaaaatcctggaagtctgcggtttagcactgaactgaaatccgcctcccaagtttgatagtggattttacacgtagttgttgaaggtataaattcatgttttgtaactgtagcggcaagtgagtttttactttttaaaaagttttaagggaataattgtaagtttctgtgcagcaaagtggctaattattcattaaatacaagaatgtagtgtctaaatccagattttttcttacctctggtacattcagattacttacctaatatgtattgaggggttttaaccctgagttttatcgacttttctagttttattttatttttataaaataattgaaaaaaacaaaaatgaattcaaaagttccataggtagatcttgccccttcttaattttctcccacaaaaaaaattttagaagacattttgaatcaaaatgtattatgaccatttaaagtttactgttttctaagaagctgagcagctaaagggcctcatttcaggtggtactgtgcgtactgtctgcggactcgtttacctgtgcggtgggtctacgtgacgatgtcttgtgcttgcaatatagaaaccgtgcagtgctgttgtgtacattgacagttcctgtataaactagtatttatatacattggcctctctgtataacttttcgtttgcttacatgaattgtaaaattaaatataaaattatagtacctgctaaatacaaatctgaggcttcctgtccttgtctttagtttaataccattctgtgtgttttgaggatgtccaatgcttgcatgatggtaggtggtaatgccactttaaattaagccttaatcagatgttaaatttgtaagtttcacagtatgcaaaaatattaggcagaatgagtttaaactgttcagatcaagatgctatatcataactcaacaagtcttttctccggagttataaagggaaactttcagtgatacagctctgtcttgctctctcgctctctctctctcgctctgtttctggtctggcttggctgttgccattgcttgatgaaaatggaccattgtgcatttctgtggcagtcagtcaaaaagacctgttctgaaagtcttgagactttttcagggttattttgaaatgtttgattttttttttt
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]