LOCUS       XM_013003682            3274 bp    mRNA    linear   MAM 06-DEC-2021
DEFINITION  PREDICTED: Echinops telfairi NRDE-2, necessary for RNA
            interference, domain containing (NRDE2), mRNA.
ACCESSION   XM_013003682
VERSION     XM_013003682.2
DBLINK      BioProject: PRJNA193504
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Echinops telfairi (small Madagascar hedgehog)
  ORGANISM  Echinops telfairi
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Afrotheria; Tenrecidae; Tenrecinae; Echinops.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_022103915.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Dec 6, 2021 this sequence version replaced XM_013003682.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Echinops telfairi Annotation Release
                                           103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 9.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 5% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3274
                     /organism="Echinops telfairi"
                     /mol_type="mRNA"
                     /isolate="266"
                     /db_xref="taxon:9371"
                     /chromosome="Unknown"
                     /sex="female"
                     /country="Germany: Ludwig Maximilians University, Munich"
     gene            1..3274
                     /gene="NRDE2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 Proteins, and 94% coverage of
                     the annotated genomic feature by RNAseq alignments"
                     /db_xref="GeneID:101644735"
     CDS             18..3056
                     /gene="NRDE2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2"
                     /protein_id="XP_012859136.1"
                     /db_xref="GeneID:101644735"
                     /translation="

MALFPAFADVGEVADSRNPRKVADLDWLHNPSFCVGAVAAPCEQPEEVHRLTSEPSPPTRSPLKSEPSDESAVGPQLKEASRKKKREKKRKRRQEHKRTERRRGRPSSSSSGSGSSSGSEPDTDADRGRSSRSVRKKDSGKPGQESPADTRCQFVWLEDVQALSGETFRMDKKPDPANWEYKCPYRGHIARYKRKGDSCLGLDPRRQRVSWEGAPAGQKRAHRRMERYFTKRSTGLLSLDSVAVSAQAEPPTTEPLGFIPVKDIGEAAPPVTTWLNPLGVYDPSTTQWLQGQGPVEQEPKPSGVQADPASALLKAKVEEFNRKVRENPRDIQLWLAFVAFQGWRAHVALTGGPAGQCQVGGHSATPMGIAAPSSLLCPLPREVGWVAAGLLAEQVKQEFCCRPDEEDEEPDEDEQEIGDRTLPRAQIWLRAERSRDRRHWRPWRPDRTKKQTEEDCEDPERQVLFDDIGQCLIRLASPELRFQLVAAFLQFLGVPCDFTPPASCLYMALDESSIFTGGLGGEKPLSRASPTFSGVSRVGRMDQFGVPCGAPGHDREGEEFIRNIFHLALPLFSGKDKARLCAAWLQHETAKVVWCLHTKAKKKLRSQGKNCRKLAKNLLREPESSSSVGLWRHYAHLEWLLGNTEDARKVFDTALSMVGAGGLRDAQLCELSLLYAQLEVELLPAAQEATASRAVHVLTGLAESTPYKPYPGHVLPVHILKARKAYEHALQDALEESCGSEPGPACRPSRLVSLAKCFMLFQYLTVGIEAAGCVHEQVWAQLKGSAVSEGSGAGSAGQPQKWAGELEAVTLLHTSLLQFHLRVSVHPLAPLREALTESLRLYPGNQALWRAYVQTQSRSHSASKTRRFFDAITRSTESLEPWLFAIETEKARKKRVETVQRVDGGEIHTTIPEIGLTNRIQALFEHAIQTDRGRQCPLLWRMYLHFLVSLGNRERSKGVFYKALQNCPWAKVLYMDALEYFPDEMQEILDLMTEKELRVRLPLEELELLLED"

     misc_feature    516..806
                     /gene="NRDE2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(516..542,549..554,564..569,573..575,579..623,
                     630..638,642..650,672..680,690..695,699..704,711..731,
                     756..767,777..806)
                     /gene="NRDE2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    <1293..1496
                     /gene="NRDE2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:429988"
     misc_feature    <1902..>2033
                     /gene="NRDE2"
                     /note="P-loop containing Nucleoside Triphosphate
                     Hydrolases; Region: P-loop_NTPase; cl38936"
                     /db_xref="CDD:453896"
     polyA_site      3274
                     /gene="NRDE2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

cggcgcggcctgccctcatggcgctgttcccagcctttgccgacgttggtgaggtcgccgacagcaggaacccccggaaagttgctgacttagactggctacacaaccccagcttctgcgtgggagctgtagcagcgccgtgtgaacagcccgaggaggtccaccgcctcacctcggagccatcaccaccaaccaggagtcctttgaagtcagagccttctgatgaaagtgccgtcggcccacagctcaaagaagcaagccgaaagaagaagagagagaagaagaggaagaggagacaggaacacaagagaactgagcggagacgtgggcggcccagcagcagcagcagcggcagcggcagcagcagtgggtctgagccggacaccgatgccgacagggggaggtcttccagaagcgtccgcaaaaaggactctgggaagccaggacaggagagtcccgccgacaccagatgtcagtttgtttggctcgaagacgtgcaggcgctgtcgggggaaaccttcaggatggacaagaagccagaccctgccaactgggagtacaagtgtccctaccgtgggcacatcgcgaggtacaagaggaaaggcgactcctgcctgggcctagatccccggaggcagcgtgtgtcttgggaaggggctccggcggggcagaagcgcgcccacaggcgcatggagcgctacttcacgaagagaagtaccgggctgctgagcttggacagcgtggctgtcagtgcccaggccgagccgcccaccaccgagcccctgggcttcatacctgtgaaggacattggtgaggcggcccctccggtcacaacctggctgaaccctctgggggtctacgacccttccaccacgcagtggctccaagggcagggccccgtggagcaggagccaaagccttcaggcgtccaggctgaccccgccagcgcccttctcaaggccaaggtggaggagttcaacaggaaggtgcgggagaatcctcgggacattcagctgtggctggcgtttgtggccttccagggctggagggcacatgtggccctcacaggaggccctgctgggcagtgccaggtgggcgggcactctgccacgcccatgggcattgctgcaccctcgtcgctcctctgccccctgccccgggaggtgggttgggtggcagcagggctgctggctgagcaggtgaagcaggagttttgttgtcgtccagatgaggaggatgaggagccggatgaggacgagcaggagataggagacaggaccctgcctcgggctcagatctggctgcgtgcagagcgctcccgagaccgccgccactggcgcccctggcgccccgacaggaccaagaagcagaccgaggaggactgcgaggaccccgagaggcaggtgctgttcgatgacatcggccagtgtctgatcagactcgccagcccagagctccggttccagctggtggcggccttcctgcagttcctgggtgtgccctgtgacttcaccccgccggcctcctgcctctacatggccttggacgagagcagcatcttcactgggggcctcggtggcgagaagcccttgagcagggccagtcccaccttctccggcgtgagccgtgtgggccgcatggaccagtttggtgttccgtgcggggccccgggccatgaccgggaaggtgaggagttcatccgaaacatcttccacctggcgctgccgctgttctccggcaaggacaaggcccgcctctgcgccgcctggctgcagcacgagactgcaaaggtcgtgtggtgtctgcatacgaaagccaagaagaaactgcggtcccaggggaagaactgcaggaagctggccaagaacctcctcagggagcccgagagcagcagcagcgtgggcctctggcggcactacgcccacctggagtggctgctgggcaacacagaggacgccaggaaggtctttgacacggcgctcagcatggtgggagctggaggcctgcgggacgcgcagctctgcgagctcagcctgctctacgcgcagcttgaggtggagctgctgccagccgcgcaggaggccacggcgtccagggcggtccacgtgctgacggggctggccgagagcaccccgtacaagccctaccccgggcacgtcttgcccgtgcacattctgaaggcccggaaggcctatgagcatgcgctgcaggacgccttggaggagagctgcggctcagagccaggtcccgcctgccgccccagccgcctggtcagcttggccaagtgcttcatgctcttccagtacttgaccgtgggcattgaggctgcggggtgcgttcatgagcaggtgtgggcgcagctgaagggctcggcagtgtctgaaggctctggagcggggtccgccgggcagccgcagaagtgggcaggcgagctggaagccgtcacactgctgcacacgagcctgctgcagttccacctgagggtcagcgtgcacccgctggccccgctgcgggaggcgctcactgagtcactgaggctgtacccgggcaatcaggccctgtggagggcgtacgtccagacgcagagcaggtctcacagtgccagcaagaccaggaggttctttgatgccatcactaggtccactgaatccctggagccttggctgtttgcgatcgagacagagaaagcgaggaagaaacgggtggagaccgttcagagggtggatggtggagaaatacataccacgatccccgagattggcttaaccaaccgcatccaggccctattcgagcacgcgatccagactgaccggggcagacagtgccccctgctgtggaggatgtacttgcattttttggtttccctgggaaatagagagagaagcaaaggtgtgttctacaaagcactccagaactgcccctgggcaaaggtgctgtacatggatgccctagagtacttcccggatgagatgcaagagatcctggacctgatgactgagaaggagctgcgggtgcgcctgcccctggaggagctggagctcctgctggaagactagagcccggcgaacagggcaagttggcggacgtcagggcgccgagcgccctatctcagcacctttcttgtttgtgtctgagctctcggcctcccacatcttcacgttggtagatgtttaaatgacacaaaacctggtgttttacatattatatatgtatctaagtacagaggaagagttgaaccaagtggtaattaaacctttgtgggttgagaagtgtg

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