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2020-12-06 00:03:13, GGRNA.v2 : RefSeq release 202 (Sep, 2020)

LOCUS       XM_011222214           15364 bp    mRNA    linear   MAM 26-MAY-2020
DEFINITION  PREDICTED: Ailuropoda melanoleuca argonaute RISC catalytic
            component 3 (AGO3), transcript variant X6, mRNA.
ACCESSION   XM_011222214
VERSION     XM_011222214.3
DBLINK      BioProject: PRJNA633539
KEYWORDS    RefSeq.
SOURCE      Ailuropoda melanoleuca (giant panda)
  ORGANISM  Ailuropoda melanoleuca
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae;
            Ailuropoda.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_048219.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On May 26, 2020 this sequence version replaced XM_011222214.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Ailuropoda melanoleuca Annotation
                                           Release 103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.4
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15364
                     /organism="Ailuropoda melanoleuca"
                     /mol_type="mRNA"
                     /isolate="Jingjing"
                     /db_xref="taxon:9646"
                     /chromosome="2"
                     /sex="female"
                     /tissue_type="blood"
                     /dev_stage="adult"
     gene            1..15364
                     /gene="AGO3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 22 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:100465651"
     CDS             190..2070
                     /gene="AGO3"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X6"
                     /protein_id="XP_011220516.1"
                     /db_xref="GeneID:100465651"
                     /translation="
MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"
     misc_feature    190..531
                     /gene="AGO3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(325..327,370..372,412..414,424..426,478..480,
                     499..501,505..507)
                     /gene="AGO3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    664..1941
                     /gene="AGO3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1075..1077,1087..1089,1123..1134,1141..1143,
                     1165..1167,1174..1176,1186..1188,1198..1200)
                     /gene="AGO3"
                     /note="5' RNA guide strand anchoring site; other site"
                     /db_xref="CDD:240015"
     misc_feature    order(1279..1281,1285..1287,1495..1497,1909..1911)
                     /gene="AGO3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      
tagatagaggagaaaaaactaatctcagaagccagttaggaggctttttcaatcactagttcaggtttcagtctacatgttacttccttgagaagcagtatttgacacctttctccccccacatccagccatcccccaagtctgatttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgacattcataatattgatgagcaaccaagacctctgactgattctcatcgggtaaaattcaccaaagagataaaaggtctgaaggttgaagtgactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacaagaaggcctgccagtcatcaaacctttcctttacagttagaaaacggccaaactgtggagagaacagtagcacagtatttcagagaaaagtatactcttcagctgaagtacccacaccttccttgtctgcaagtggggcaggaacagaaacatacctacctgccactagaagtatgtaatatcgtggcagggcaacgatgtatcaagaagctaacagacaatcagacttccactatgatcaaagcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcaatttaaggttcgggatgaaatggctcatgtaaccggacgtgtactcccagcacccatgctacagtatggaggacggaatcggacagtagcaacaccaagccatggagtatgggacatgcgggggaagcaatttcacacaggagttgaaataaaaatgtgggctatagcttgttttgccacacagaggcagtgcagagaagaaatactgaagggtttcacggaccagctgcgtaagatttcaaaggatgcagggatgcccatccagggccagccttgcttctgcaaatacgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactctgggctacagctcattatcgtcatcctgccagggaagacgccagtgtatgcggaagtgaaacgtgtaggagatacacttttgggtatggccacgcagtgtgtccaagtcaagaatgtaataaaaacatctcctcaaactctctcaaacctgtgcctaaagataaatgttaaactcggagggatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagcagatgtcactcatccaccagctggtgatgggaagaagccttcgattgctgctgttgtaggtagtatggacgcccacccaagcagatactgtgccacagtaagagttcagagaccccgacaggagatcatccaggacttggcctccatggttcgagaacttctcattcagttttataagtcaactcggttcaaacctactcgtatcatcttttatcgggatggtgtttcagagggccagtttaggcaggtattatattatgaactactagcaattcgagaagcctgcatcagtttggagaaagactatcaacctggaataacctacattgtagttcagaagagacatcacactcgattattttgtgctgataggacagaaagggttggaagaagtggcaatatcccagctggaacaacagttgatacagatattacacacccatatgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgtccttcacactatcatgttttatgggatgataactgctttactgcagatgaacttcagctgctaacttaccagctctgccacacttatgtgcgctgtacacgatctgtttctatacctgcaccagcgtattatgctcacctggtggcattcagagccagatatcatctcgtggacaaagaacatgacagtgctgaaggaagtcacgtttcaggacagagcaatgggcgagatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtactttgcttaaaaagtccaagaatattctctgagaggaagaactgaaagatgcatcgacatacagcatatgtttccagtggagtcagttaagtggggatgcctccagccatacagcaaccaacactgtgtggggaccagggtctgatttttatgttgatacaaggaagattgtttacttcatcaaggaacacagcaccattatgcaatatgaaaccagccaactgcttttttgtgcggtctccttaggaagtatcgccattgttttgttttcactttcttgtagtctaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaaaaaaaagtaaagaaaaagtaaatgacagtttaaaaaaaaaaacacacctacatgaataatcaaagtgattgttcacgattatgtgtgcaaaaaaattaatgtgcattcgtgtattcttgtaaaaggtatctgtgtatattttaaatatatacatgtatacttcacatgcatatatatctagatctacactgataatagatatatatgtgtctgtgcgtgtattttatagttcattccactggggaactttctttcccttttattattttcccaccaccactttgatttttctctctacctcccttgccttcatcacctacatttttttttcctaatgctaccagtgacattcagatgttcatgtatctggttcatttggatatgaagcatggcaaactagatttttatttttaattttgcacaccctactcctgtctcttgtctcatacacaattgcaagtcctcaactcttgatattgctttcttaagaaacaaaattttatatatatatacatatatatgtgtgtatatatataatgtttctgtgagagtgcgtgtctgccccctcctgctctgaaactacatttgccatttgtgcaatgtgtacataagcagtagcaaccgtaaactattctttttctttattttgttaaagctgctataaatataaaaccttgtcagaagttgtaactcagaaatttctctctgtaagtgatatgtattctaaagccttctgtttctatgggttatacatgaaaatcccttatagcttttataaagggcaaatattctaaatgattggaactctttagggttgaggcctctgaaattgggtggagagagagaaggtgttcttgaggggttttttaattttaattttttttttttgctagtttacttgctgcctctcataccttaatgtgattttcatatatatatatttttatatatatgtgcgtatatataaacatatatgtatgtgttttgaagtacagcttccttttctttcatatttattagaatagtgctttaataattagagaactgtattggcaacatcttttatagaaatgtaatcatgtttattttaagaactgacaacttgttctgctgtcttttagtgcaataagcagttttaaaggaaagctgtgtccgtttgatatctttaccacggatagtgggagaaacagcacctccataattttaaaagggcaaagtaatacagccttaatttcagaaggaaagttttgtaatttttcaagtttaaagcctgtcttctaaaaattgtaatgaaaatgaaggaagttaaatttcctaagtgaatttgaccttgaatattagagataagagttgagctttgatttaagaaatgacagtgagtaggggcacctggctggctccgtcactagagcatgtgactcttgatctcggggttgtgagttcaagccccacattggtcacggagcctacttaaaaaaaaaaaaaaaagtgaatagcttaatatttagaagacatttaattctttgaaaataaatcacgtttattgaacaatcatactgattaggtgcccattttcatttactcaaatgaatcaggaaaatataaaatgatattttaaaaacattttttgccaatttatcagcagtgtaactttccttttaaaattagggttacggtggcaaaggaagttaggagtttgatcattttaaataagttaaatcactgaaatgtggaagaagatttacattgattctgttttattgatttcactttaagatattcagaagtattatagagctgtcaaaatcgagttcatcagtaacattggattcaggggagctttgcactttgtgactcatgaaaattgcattttaattttttttttcttttttgcactggttcagagtatagatactacagatagtttccagtgggcattgttaaacctttcagaattccatctgcacatggtaacaaatggattagctcttcagtttctctcttacctgtaatccacttttattgccaatttactgtattttgagcctaaaatctgagcccatgtcctccaacaggtatgaaatcttttgttttcctctgccagaaaactaagaaagtactgtattttgtatgtttattattgaagtgtctgaaatgcaatttataacactgtttcaaagctctttacatgaagtaatatttgtatagtatatacattttttctcccaaccctccccctctcctccaaaaatttcctagaaagcatgtatttttttttaacattgaaatttcactgaatatagtcgggaacatgaataggagaagaaaatagtgtatcctagatgctaaaaccttgattgctgtgtgctttctcagtatgagtaagacaccttcctttaccaatggaagttacacagacttaatgtgggaaactgtagggcccaggaaagaattgtagataccttttccctatttactgcttcaccttagtttccatatgctagaatgaaacccataatttaaatctatttagaaggacttttactgaggaaaaacaatttttttaatataaagctttacctttaaagtgagtt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gtaagaacaatttactgtagtaatataaagactgcagaatttcaaaatgtttataagcctttctttgttaatgtttggttacacagtaacatcagttaaaacagtggagtctgagtttgtaatatgctgtatgaccagataagatcttgataggaaacttgactgccacgttttattaagaggaaagcggaggtgggagcaaactacagtatatatgtaatctgtgtataattagaaacaccaaatgccgaattctatcactgtgtacttgggggccaggctttggatttggttgtcattttaattccttgaagactatatgtaattatgatgagcagaaggcaaataaagtttttaaacaaaa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]