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2020-12-05 23:52:34, GGRNA.v2 : RefSeq release 202 (Sep, 2020)

LOCUS       XM_004266468           12899 bp    mRNA    linear   MAM 15-APR-2020
DEFINITION  PREDICTED: Orcinus orca argonaute RISC component 1 (AGO1),
            transcript variant X2, mRNA.
ACCESSION   XM_004266468
VERSION     XM_004266468.3
DBLINK      BioProject: PRJNA189949
KEYWORDS    RefSeq.
SOURCE      Orcinus orca (killer whale)
  ORGANISM  Orcinus orca
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha;
            Cetacea; Odontoceti; Delphinidae; Orcinus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_004438433.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 15, 2020 this sequence version replaced XM_004266468.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Orcinus orca Annotation Release 102
            Annotation Version          :: 102
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.4
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12899
                     /organism="Orcinus orca"
                     /mol_type="mRNA"
                     /isolate="Morgan"
                     /db_xref="taxon:9733"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="blood"
                     /collection_date="06-Sep-2011"
                     /note="Norwegian herring-eating population"
     gene            1..12899
                     /gene="AGO1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 10 mRNAs, 43 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 63 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:101279452"
     CDS             219..2792
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X2"
                     /protein_id="XP_004266516.1"
                     /db_xref="GeneID:101279452"
                     /translation="
MEAGPSGAAAGTYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"
     misc_feature    318..710
                     /gene="AGO1"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:339747"
     misc_feature    744..890
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:337161"
     misc_feature    891..1253
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1047..1049,1092..1094,1134..1136,1146..1148,
                     1200..1202,1221..1223,1227..1229)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1386..2663
                     /gene="AGO1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1797..1799,1809..1811,1845..1856,1863..1865,
                     1887..1889,1896..1898,1908..1910,1920..1922)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site; other site"
                     /db_xref="CDD:240015"
     misc_feature    order(2001..2003,2007..2009,2217..2219,2631..2633)
                     /gene="AGO1"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      
gcactggcagcgggccgggcgctagctgggggagctgctgcaggctccgcggcggcggctgcaacggaggctgcgggggcggcggcgcgagcggccgggcttgggggggtagccgagcccggcccgggagcccaagcagctaaagtgcggggtacctaggcccttcacgctggactccacagtctccgggccgcctgacctccgcacgggtatatgggatggaagcgggaccctcgggagcagctgcaggcacctacctgccccccctgcagcaggtgttccaggcacctcgccggcctggcattggcaccgtggggaaaccaatcaagcttctggccaactactttgaagtggacatccctaagattgacgtctaccactacgaggtggatatcaagccggataagtgtcctcgcagagtcaaccgggaagtggtggaatacatggtccagcatttcaagcctcagatctttggtgatcgcaagcccgtgtatgatggaaagaagaacatttacactgtcacagcactgcccattggcaatgaacgggttgacttcgaggtgacaatccctggggaagggaaggatcgaatcttcaaggtctccatcaagtggctagccattgtgagctggcgcatgctgcatgaggccttggttagtggccagatccccgttcccctggagtctgtgcaagccctggatgtggccatgaggcacctggcatccatgaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttctacaaggcgcagccagtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcagcccaagcccctcacggactctcagcgtgtgcgcttcaccaaggagatcaagggcctgaaggtggaagtgacccactgtggacagatgaagaggaaataccgcgtgtgtaatgttacccgccgccctgccagccatcagacgtttcccttgcagctggagagtggacagactgtggagtgcacagtggcacagtatttcaagcagaaatataaccttcagctcaagtatccccacctgccctgcctgcaagttggccaggaacaaaagcatacctacctgcccctagaggtctgtaacattgtggctgggcagcgctgcattaagaagctgactgacaaccagacttcaaccatgataaaggctacagctagatcggccccagacagacaagaggagatcagccgcctgatgaagaatgccagctacaacctagatccctacattcaggaatttgggatcaaggtgaaggatgacatgacggaggtgacggggcgagtgctgccggcgcccatcttgcagtacggcggccggaaccgggccattgccacacccaatcaaggtgtctgggacatgcgggggaaacagttctacaatggaattgagatcaaagtctgggccattgcctgcttcgcaccccaaaaacagtgtcgagaagaagtgctcaagaacttcacagaccagctgcggaagatttccaaggatgcagggatgcccatccagggccagccttgcttctgcaaatatgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgccagggaagacgccagtgtatgctgaagtgaagcgtgttggagatacactcttgggaatggctacacagtgtgtgcaagtgaagaatgtggtcaagacctcgcctcagactctgtccaacctttgcctgaagatcaatgtcaaacttggtggcattaacaacatcctagttccacaccaacgctctgctgtctttcaacaaccagtgatattcctgggagcagatgttacacaccccccagcaggggatgggaaaaaaccttctatcacagcagtggtaggcagtatggatgcccaccccagccgttactgtgctactgtgcgggtgcagcgacctcggcaggagatcattgaagacttatcctacatggtacgtgagctgctcatccagttctacaagtccacccgcttcaagcctacccgcatcatcttctaccgagatggggttcctgaaggccagctcccccagatcctccactatgagctgctggccattcgtgatgcctgcatcaaactggaaaaggactaccagcccgggatcacttatattgtggtgcagaaacgccatcacacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggaccactgtggacaccaacatcacccacccatttgagtttgacttctatctgtgcagccacgcaggcatccagggcaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcggatgagctccagatcttgacgtaccagctgtgccacacttacgtacgatgcacacgctccgtctcaattccagcacctgcctactatgcccgcttggtggctttccgggcacgataccacctagtggacaaggagcatgacagtggagaggggagccacatatcggggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaagagctgtgccgcccaaatccagaggaagcagggaggagggaggtggggcagggaggaatgcagaaggccttgtttcctctacagagggggcgaaagggtggggaacagggccagtaagccagaccaccagccagaaatctctgatattcacctcatgccctccacccctcaccccatcttgtcacatctggccctgactccactggaccaagagaggcagccccggtgcccaccatacacacagatgtcgcatgtgactcacagtgctaaagactcatgcctgacagcttggtaaggtcggccctgcagccctgcagacaaaagctggtaggtttgggtttgatactttagatgggaaagtgaggggcttgaaaagtgggtgggaggagggaaggattttttaggagccttaatcagaaaaggtctagatttgtttaagaagaaaaacgaaaccagatgcagatcaatattttaggatactagatgttttaatgggttgagaatccagcttgtaggaagatttttaatgctaatgatttggttgcccctcccccagctgccactcctctttcccttattcctctttttccaccttttctaccccaccttacaccttctccctgacagacatccagcccctagtaagacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctgctggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctatttttgggggggtgggggcggggtgggggtgggagaggaggtaggtggggatgaaatacccctaacccaacaagcctccagccagagcgccagctattttgcatttgaaggagttgacttccatattcattgagcttttaaaaagatcgccacctcaagatggttaaaatccattgacatttgcactttcagacatgacaagtctctcagagctgctgaggtgactggcctctggcctttccacttacgtctcctttcttcctgtccccgcttcctccccacctgcctgggtctggagttactttcatagcatttctcactcttggcttcttttttttccctgacgatcaagtctgtttatgtttcaatattttttaactggggtgtcttttaacaaacgatccttaggtctaaaataagaaaaaaaaaaaaagcaaaaactaaatgttatttttataccataacttgagtctattgccaaaatctggaaatccctcccatgcccaatgagtttacatcccagaaacattgagccgtcagaaggaactatgtacctgacttgttctttggcctggctctgtagggggtggttatctccccaaggtggggctcagtctccaccctcctctgtgcagataatatctttctcttgctgcaggcaccccttctgcactgccctgcactcttttctgcaagtgcatcttcccttcctctggactgtcctctgacactttggcttatcccagatttcagtgtgtcctgtggataggctggggaattttgctgctcccttttgcttctgtttacacaaatgaatttttcctgatttcccactagggcatgtgagtgggtggcatgggctttttaaaaaattttttcctgtcttcctgggtagagatggggtttggctgtgttgcagaactggaaaagtagggggttctagcttggggcctgttggccttgaagcaaggcttcctcatttcttgactgttcattttttcctgtcccactgcttgggatgaggagttgcagcttcagtgtggaaattcctctttttgaggagcctgggcttgggcttgccccaatctggtgatgaagccacgacactttagacctagctcaggcttggaggccagccagaggaaggctggtctgaatatgggcgtatgaagttagagctaccatttcccctccccagcagcctttgtacagacccagatttgctatgcaaaacagtctatcccaggttctgttctggttggctactttgttcagcaacttcacaaaacgtagcacaaacattgattatggagaaggcatcagggctgttgagtaactcttcctttacttctttcctgctggctacagtgtggggtgccccatgggca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//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]