GGRNA ver.2 Home | Help | Advanced search    Previous release (v1)

2019-03-25 14:42:44, GGRNA.v2 : RefSeq release 92 (Jan, 2019)

LOCUS       NM_022175                636 bp    mRNA    linear   ROD 15-SEP-2018
DEFINITION  Rattus norvegicus Rhox homeobox family member 5 (Rhox5), mRNA.
ACCESSION   NM_022175
VERSION     NM_022175.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   MacLean JA 2nd, Hayashi K, Turner TT and Wilkinson MF.
  TITLE     The Rhox5 homeobox gene regulates the region-specific expression of
            its paralogs in the rodent epididymis
  JOURNAL   Biol. Reprod. 86 (6), 189 (2012)
   PUBMED   22423045
  REMARK    GeneRIF: regulates the expression of other Rhox genes in the
            epididymis
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 636)
  AUTHORS   Bhardwaj A, Song HW, Beildeck M, Kerkhofs S, Castoro R, Shanker S,
            De Gendt K, Suzuki K, Claessens F, Issa JP, Orgebin-Crist MC and
            Wilkinson MF.
  TITLE     DNA demethylation-dependent AR recruitment and GATA factors drive
            Rhox5 homeobox gene transcription in the epididymis
  JOURNAL   Mol. Endocrinol. 26 (4), 538-549 (2012)
   PUBMED   22322598
  REMARK    GeneRIF: GATA factors collaborate to dictate the unique
            developmental and region-specific expression pattern of the RHOX5
            homeobox transcription factor in the caput epididymis.
REFERENCE   3  (bases 1 to 636)
  AUTHORS   MacLean JA 2nd, Rao MK, Doyle KM, Richards JS and Wilkinson MF.
  TITLE     Regulation of the Rhox5 homeobox gene in primary granulosa cells:
            preovulatory expression and dependence on SP1/SP3 and GABP
  JOURNAL   Biol. Reprod. 73 (6), 1126-1134 (2005)
   PUBMED   16093360
  REMARK    GeneRIF: expression in the ovary is governed by the distal promoter
            and is expressed at least as early as Day 5 postpartum. mRNA levels
            are regulated during the ovarian cycle, peaking before ovulation
REFERENCE   4  (bases 1 to 636)
  AUTHORS   Rao MK, Maiti S, Ananthaswamy HN and Wilkinson MF.
  TITLE     A highly active homeobox gene promoter regulated by Ets and Sp1
            family members in normal granulosa cells and diverse tumor cell
            types
  JOURNAL   J. Biol. Chem. 277 (29), 26036-26045 (2002)
   PUBMED   11986330
  REMARK    GeneRIF: Pem promoter may be a useful model system to understand
            the molecular mechanism by which a tissue-specific promoter can be
            corrupted in tumor cells
REFERENCE   5  (bases 1 to 636)
  AUTHORS   Maiti S, Doskow J, Li S, Nhim RP, Lindsey JS and Wilkinson MF.
  TITLE     The Pem homeobox gene. Androgen-dependent and -independent
            promoters and tissue-specific alternative RNA splicing
  JOURNAL   J. Biol. Chem. 271 (29), 17536-17546 (1996)
   PUBMED   8663309
REFERENCE   6  (bases 1 to 636)
  AUTHORS   Maiti S, Doskow J, Sutton K, Nhim RP, Lawlor DA, Levan K, Lindsey
            JS and Wilkinson MF.
  TITLE     The Pem homeobox gene: rapid evolution of the homeodomain, X
            chromosomal localization, and expression in reproductive tissue
  JOURNAL   Genomics 34 (3), 304-316 (1996)
   PUBMED   8786129
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U52034.1.
            
            Summary: homeodomain-containing protein; may regulate
            androgen-dependent events in the epididymis [RGD, Feb 2006].
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ058653.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq35"
     gene            1..636
                     /gene="Rhox5"
                     /gene_synonym="Pem"
                     /note="Rhox homeobox family member 5"
                     /db_xref="GeneID:24631"
                     /db_xref="RGD:3295"
     CDS             1..636
                     /gene="Rhox5"
                     /gene_synonym="Pem"
                     /note="homeobox protein Pem; reproductive homeobox on
                     chromosome X 5; placenta and embryonic expression protein;
                     placentae and embryos oncofetal; Homeobox gene Pem;
                     reproductive homeobox 5"
                     /codon_start=1
                     /product="homeobox protein Rhox5"
                     /protein_id="NP_071511.1"
                     /db_xref="GeneID:24631"
                     /db_xref="RGD:3295"
                     /translation="
MEAQGSSHDISRLLCLGVKEDSEEQHGQYLGDVKAEAFFQAGEGRDEKGAQGQPGEGAVGTEGEGEELNGGEGHFGPGVPGPVGEGDKDGGTRASGMEEEQHEPVAEGTESVKSEDKQMPLRRPGSTQRRLAELERILLSSGSSSGGRSLIDGWISVCPECRNWFKIRRAAYRRNRRRRTPIPEHFRATSGCPACLGARWGVRCPFATPRF"
     exon            1..93
                     /gene="Rhox5"
                     /gene_synonym="Pem"
                     /inference="alignment:Splign:2.0.8"
     exon            94..438
                     /gene="Rhox5"
                     /gene_synonym="Pem"
                     /inference="alignment:Splign:2.0.8"
     exon            439..485
                     /gene="Rhox5"
                     /gene_synonym="Pem"
                     /inference="alignment:Splign:2.0.8"
     exon            486..636
                     /gene="Rhox5"
                     /gene_synonym="Pem"
                     /inference="alignment:Splign:2.0.8"
ORIGIN      
atggaggctcaaggctctagccatgatatcagccgcttactctgcctgggagtcaaggaagactcggaagaacagcatggtcagtacctgggtgatgtgaaagcagaggctttctttcaggctggagaggggagagacgagaaaggtgcacagggtcagcctggagagggagcagtgggaacagaaggcgaaggagaagaattaaatggaggagaaggccactttggtcctggtgttccaggtcctgtgggtgagggggacaaggatggtggcaccagagctagtggcatggaggaggagcaacatgagcccgttgccgagggcactgagagtgtcaagtctgaggataagcagatgccactccgccgccctgggtccacccagcggcggctggcggaattggagcgcattttgctaagcagtggttcctccagtggcgggaggagcttgatagatggatggatatcagtgtgtccagagtgcaggaattggtttaagattaggagggctgcatacagaagaaataggaggcggagaacaccaatccctgaacattttagagcaacatctgggtgccctgcttgtcttggagcaagatggggagtaagatgtccttttgcaacaccgagattttga
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]