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2024-03-29 19:53:42, GGRNA.v2 : RefSeq release 222 (Jan, 2024)

LOCUS       NM_010835               1931 bp    mRNA    linear   ROD 12-NOV-2023
DEFINITION  Mus musculus msh homeobox 1 (Msx1), mRNA.
ACCESSION   NM_010835
VERSION     NM_010835.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1931)
  AUTHORS   Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y and
            Zhou B.
  TITLE     Crk and Crkl Are Required in the Endocardial Lineage for Heart
            Valve Development
  JOURNAL   J Am Heart Assoc 12 (18), e029683 (2023)
   PUBMED   37702066
REFERENCE   2  (bases 1 to 1931)
  AUTHORS   Kim EJ, Kim HY, Li L, Tang Q, Kim KH, Ohshima H and Jung HS.
  TITLE     Cuspal Shape Alterations by Bmp4 Directing Cell Proliferation and
            Apoptosis
  JOURNAL   J Dent Res 102 (7), 825-834 (2023)
   PUBMED   37246809
REFERENCE   3  (bases 1 to 1931)
  AUTHORS   Liu H, Lu P, He S, Luo Y, Fang Y, Benkaci S, Wu B, Wang Y and Zhou
            B.
  TITLE     beta-Catenin regulates endocardial cushion growth by suppressing
            p21
  JOURNAL   Life Sci Alliance 6 (9), e202302163 (2023)
   PUBMED   37385754
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1931)
  AUTHORS   Han JS, Fishman-Williams E, Decker SC, Hino K, Reyes RV, Brown NL,
            Simo S and Torre A.
  TITLE     Notch directs telencephalic development and controls neocortical
            neuron fate determination by regulating microRNA levels
  JOURNAL   Development 150 (11) (2023)
   PUBMED   37272771
REFERENCE   5  (bases 1 to 1931)
  AUTHORS   Lu C, Zhang J, Wang B, Gao Q, Ma K, Pei S, Li J and Cui S.
  TITLE     Casein kinase 1alpha is required to maintain murine hypothalamic
            pro-opiomelanocortin expression
  JOURNAL   iScience 26 (5), 106670 (2023)
   PUBMED   37168577
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1931)
  AUTHORS   Song K, Wang Y and Sassoon D.
  TITLE     Expression of Hox-7.1 in myoblasts inhibits terminal
            differentiation and induces cell transformation
  JOURNAL   Nature 360 (6403), 477-481 (1992)
   PUBMED   1360150
REFERENCE   7  (bases 1 to 1931)
  AUTHORS   Scott,M.P.
  TITLE     Vertebrate homeobox gene nomenclature
  JOURNAL   Cell 71 (4), 551-553 (1992)
   PUBMED   1358459
REFERENCE   8  (bases 1 to 1931)
  AUTHORS   Lyons GE, Houzelstein D, Sassoon D, Robert B and Buckingham ME.
  TITLE     Multiple sites of Hox-7 expression during mouse embryogenesis:
            comparison with retinoic acid receptor mRNA localization
  JOURNAL   Mol Reprod Dev 32 (4), 303-314 (1992)
   PUBMED   1353971
REFERENCE   9  (bases 1 to 1931)
  AUTHORS   Wang Y, Benezra R and Sassoon DA.
  TITLE     Id expression during mouse development: a role in morphogenesis
  JOURNAL   Dev Dyn 194 (3), 222-230 (1992)
   PUBMED   1361374
REFERENCE   10 (bases 1 to 1931)
  AUTHORS   MacKenzie A, Ferguson MW and Sharpe PT.
  TITLE     Expression patterns of the homeobox gene, Hox-8, in the mouse
            embryo suggest a role in specifying tooth initiation and shape
  JOURNAL   Development 115 (2), 403-420 (1992)
   PUBMED   1358591
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY240100.1, AC114671.14, BU922533.1 and AV323104.1.
            
            On Aug 25, 2006 this sequence version replaced NM_010835.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077524.1, X14759.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-121               BY240100.1         2-122
            122-459             AC114671.14        5722-6059
            460-1059            BU922533.1         1-600
            1060-1853           AC114671.14        8824-9617
            1854-1931           AV323104.1         93-170
FEATURES             Location/Qualifiers
     source          1..1931
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 20.21 cM"
     gene            1..1931
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /note="msh homeobox 1"
                     /db_xref="GeneID:17701"
                     /db_xref="MGI:MGI:97168"
     exon            1..721
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /inference="alignment:Splign:2.1.0"
     CDS             253..1164
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /note="hox-7.1; homeobox protein Hox-7; msh homeobox
                     1-like protein; muscle-segment homeobox; homeo box,
                     msh-like 1; homeobox, msh-like 1"
                     /codon_start=1
                     /product="homeobox protein MSX-1"
                     /protein_id="NP_034965.2"
                     /db_xref="CCDS:CCDS19249.1"
                     /db_xref="GeneID:17701"
                     /db_xref="MGI:MGI:97168"
                     /translation="
MAPAAAMTSLPLGVKVEDSAFAKPAGGGVGQAPGAAAATATAMGTDEEGAKPKVPASLLPFSVEALMADHRKPGAKESVLVASEGAQAAGGSVQHLGTRPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKLDRTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYSASGPFQRAALPVAPVGLYTAHVGYSMYHLT"
     misc_feature    316..411
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /note="propagated from UniProtKB/Swiss-Prot (P13297.4);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    520..588
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /note="propagated from UniProtKB/Swiss-Prot (P13297.4);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    <547..>996
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /note="104 kDa microneme/rhoptry antigen; Provisional;
                     Region: PTZ00449"
                     /db_xref="CDD:185628"
     misc_feature    655..741
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /note="propagated from UniProtKB/Swiss-Prot (P13297.4);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    769..1065
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /note="propagated from UniProtKB/Swiss-Prot (P13297.4);
                     Region: Required for interaction with EHMT2.
                     /evidence=ECO:0000269|PubMed:22629437"
     misc_feature    order(769..783,787..789,838..840,856..858,895..897,
                     901..906,913..918,922..930,934..939)
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    775..936
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    order(775..777,784..786,904..906,913..918,925..927)
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     exon            722..1931
                     /gene="Msx1"
                     /gene_synonym="Hox-7; Hox7; Hox7.1; msh"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
ggcggacccggagccggcgagtgcgcctgggaactcggcctgagcggcgcagggatccaggccccgctcgctcgagttggccttctggggaagccgcaggaggctcgcgcgcgagagccggccgggccaggaacccaggagctcgcagaagccggtcaggagctcgcagaagccggtcgcgctcccagcctgcccgaaacccatgatccagggctgtctcgagctgcggctggagggggggtccggctctgcatggccccggctgctgctatgacttctttgccactcggtgtcaaagtggaggactccgccttcgccaagcctgctgggggaggcgttggccaagcccccggggctgctgcggccaccgcaaccgccatgggcacagatgaggagggggccaagcccaaagtgcccgcttcactcctgcccttcagcgtggaggccctcatggccgatcacaggaagcccggggccaaggagagcgtcctggtggcctccgaaggggctcaggcagcgggtggctcggtgcagcacttgggcacccggcccgggtctctgggcgccccggatgcgccctcctcgccgcggcctctcggccatttctcagtcggaggactcctcaagctgccagaagatgctctggtgaaggccgaaagccccgagaaactagatcggaccccgtggatgcagagtccccgcttctccccgcccccagccagacggctgagtcccccagcatgcaccctacgcaagcacaagaccaaccgcaagcccaggacgcctttcaccacagctcagctgctggctctggagcgcaagttccgccagaagcagtacctgtctattgccgagcgcgcggaattctccagctcgctcagcctcaccgagacccaggtgaagatctggttccagaaccgtcgcgctaaggccaagagactgcaggaggcggagctggagaagctgaagatggccgcgaaacccatgttgccgcctgctgccttcggcctctcttttcctcttggcggtcctgcagcggtggctgcagctgcgggcgcctcactctacagtgcctctggccctttccagcgcgccgcgctgcctgtagcgcccgtgggactctacaccgcccatgtaggctacagcatgtaccacctgacttaggtgggtccagagtcacctccctgtggtgccatcccctccccagccacctctttgagcagagcagcgggagtccttcctaggaagctctgctgccctataccacctggtcccttctcttaaaccccttgctacacacttcctcctggttgtcgcttcctaaaccttcctcatctgaccccttctgggaagaaaaagaatggtcggaagtgtctaggtttttcgagaaaaatctagatttacatgcgcaagttataaatgtggaaactaagggtgcagaggccaagagatttatccgtggtccccagcagaattagaggctgaaggagaccagaggccaaaaggactagaggccatgagactccatcagctgcttccggtcctgaaaccaggcaggacttgcacagagaaattgctaatcggtgcttcaagagatgagcccagccctatagaaagcaaggagcccagctccttccactgtcaaactctaagcgctttggcagcaaagcattgctctgagggggcagggcgcatgctggtgcttcaccaaggtaggttaaagagactttcccaggaccagaaaaaaagaagtaaaaaaaaaaaaaaaaaaaaccaaaatctgtttctatttaacagtacattttcgtggctctcaagcatcccttttgaagggactgtgtgtgtactatgtaatatactgtatatttgaaattttattatcatttatattatagctatatttgttaaataaattaattttaagctacaag
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]