LOCUS       NM_001134095            3427 bp    mRNA    linear   PRI 10-MAR-2024
DEFINITION  Pongo abelii PBX/knotted 1 homeobox 2 (PKNOX2), mRNA.
ACCESSION   NM_001134095
VERSION     NM_001134095.1
KEYWORDS    RefSeq.
SOURCE      Pongo abelii (Sumatran orangutan)
  ORGANISM  Pongo abelii
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Pongo.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CR860477.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR860477.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2058383, SAMN07839603
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3427
                     /organism="Pongo abelii"
                     /mol_type="mRNA"
                     /db_xref="taxon:9601"
                     /chromosome="9"
                     /map="9"
     gene            1..3427
                     /gene="PKNOX2"
                     /note="PBX/knotted 1 homeobox 2"
                     /db_xref="GeneID:100174645"
     misc_feature    209..211
                     /gene="PKNOX2"
                     /note="upstream in-frame stop codon"
     CDS             221..1639
                     /gene="PKNOX2"
                     /note="PBX/knotted homeobox 2"
                     /codon_start=1
                     /product="homeobox protein PKNOX2"
                     /protein_id="NP_001127567.1"
                     /db_xref="GeneID:100174645"
                     /translation="

MMQHASPAPALTMMATQNVPPPPYQDSPQMTATTQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFVNARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDNATMAMQQAMMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDELQTTNVSDLGLEHSDSLV"

     misc_feature    221..406
                     /gene="PKNOX2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5R6L1.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    <227..>418
                     /gene="PKNOX2"
                     /note="biotin carboxyl carrier protein of acetyl-CoA
                     carboxylase; Region: PLN02983"
                     /db_xref="CDD:215533"
     misc_feature    506..763
                     /gene="PKNOX2"
                     /note="N-terminal of Homeobox Meis and PKNOX1; Region:
                     Meis_PKNOX_N; pfam16493"
                     /db_xref="CDD:465140"
     misc_feature    order(1085..1099,1103..1105,1163..1165,1181..1183,
                     1220..1222,1226..1231,1238..1243,1247..1255)
                     /gene="PKNOX2"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(1091..1093,1100..1102,1229..1231,1238..1243,
                     1250..1252)
                     /gene="PKNOX2"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    1139..1255
                     /gene="PKNOX2"
                     /note="Homeobox KN domain; Region: Homeobox_KN; pfam05920"
                     /db_xref="CDD:428673"
     misc_feature    1271..1333
                     /gene="PKNOX2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5R6L1.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1376..1435
                     /gene="PKNOX2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5R6L1.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1487..1636
                     /gene="PKNOX2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5R6L1.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
ORIGIN      

ggatgaagattggcatcaggtgaagtctggagcaggacttctgaagctttctatcctccatgctgctcactagaaaaggggctgtgaactgtgctttggctctagcagacaggaagaaattctggcccagctggaagtagaaagaggggagtgagtctcctgaggaccatctcagaggcccccgggatcacccgaacagtcctccatgtgaatcaatcccatgatgcaacatgcctccccagcccccgctctgacgatgatggccacgcagaatgtcccgcccccaccctaccaggacagcccacagatgacggcaaccacccagccaccctccaaggcccaggctgtccacatctctgccccctcagctgctgccagcacacctgtgcccagtgcccccatcgacccccaggcccagctggaggctgacaagcgagctgtatacaggcaccctcttttcccgctcctgacgctgctgtttgagaaatgtgaacaggccacccagggctctgagtgcatcacctccgccagctttgatgtggacatcgagaactttgtccaccaacaggaacaggagcacaaacccttcttcagcgatgacccagaactggacaatctgatggtgaaggcaatccaggtcctgagaatccacctgctggagctggagaaagtcaatgaactctgcaaggacttttgtaaccgttacatcacctgcctcaaaaccaagatgcacagcgataacctgctcaggaatgatctaggggggccatactcccccaaccagccctccatcaaccttcactcacaggacctcctgcagaattcccccaattccatgtctggagtctccaataacccccaggggattgtggtcccagcctcagcgctccagcagggcaacatcgccatgacaaccgtcaactcacaagtcgtgtcaggtggagccttataccaaccggttaccatggtaacctcccagggtcaggtggtcacccaagcaatcccccagggagccatccagatccagaacacacaggttaaccttgacctcacctccctcctggacaatgaggataagaagtccaagaacaaacgaggagtcttgcccaagcatgccaccaatataatgcgttcttggctcttccagcatctcatgcacccctaccccacggaggatgagaagaggcagatcgcagcccagaccaacctcaccctcctgcaagtaaacaactggttcgtcaatgcccggaggcgcatcctgcagcccatgcttgatgccagcaacccagatcctgcccccaaagccaagaagatcaagtcccagcaccggcccacccaaagattctggcccaactccatcgctgcgggggtgctgcagcagcagggtggtgccccagggacaaaccccgatggttccatcaacttagacaacctgcagtccctgtcctcagacaatgccaccatggccatgcagcaggctatgatggctgcacacgatgactcattggatgggacagaagaagaggatgaggatgagatggaagaggaggaggaggaggagctggaggaggaggtcgatgagctgcagacgacgaatgtcagcgacctgggcttggaacacagtgactccctggtgtagtcgggcagcccagatggcactgatcaccgagcaggagaggagtgtcgccgggaggccttcagggtgggggggaaggggacatgggcaggaagcactgagggagttgggccctagcttccccaaatcagtagcttgaagaaaggcagaggagacacctgttccttcccaaccaccgagcctcaatgaggaccccagccccacttccctggaactgctgaggactctgtttggtggggccagtcgagcagcctgtatggaaagacaggactgagatctggactcaccaaatccctgaggacagatggcacccatggcccccacccacggaaggacttgagttgtttacaagccctgcactgtgaggcagattggtgctgttcgcagagtaggcctttgcccgggggcagacttagaaggaaggggagagacaaagggggactgagtttcatccccagaaggttctcagctcctttgacagacattcaagggcaggagggagccccaaagcataaccagtggccagaggagtgggagggcctgaggcatcacatcttgcagatcagaatgggatggaatccaccgggctccagctcatccctccaaggccctgtctctgcgcacagcaaccatggacatgggagagagggatgggagccacagtgcccttcactctctcctggaaacaaattgtaagctggtgggctcaacctgtgggaggttaagaggagtcccttctgggttgactccaggagccaaggagatggcagaccctgggctaggagccatatcgaggtgactttgaggccacagctgtccctaggtggtcacagaacttagctcctgtaacaacaggacaatggtgttttaccctagatgttcccaccctcagcactccacgccctccatagaccttcagagaaggcgaaaccaggttatctgggaatctttccaccccgcaggtcgccacggccgtccctctgctcccaggctggctccatccgcctccagcttcctttcttcattctgtccttcagggaaggcagaagaaacattggaaagcatctagtccagtgggaagccaggggttggagaaggtgctacatccctcttcccatcaatatcccaaatgtgggggaggtcccagagaacggcacccaagagcctgtgggaatgcccaccccacccaccccatccaccctgctgttctaaccctgctgtccacagccctggaggaactggggctcctggaaagaggaggaggctctccactgtccaccctaacacataccctcccacccaccttccataccccttggttggcacgctctcctctcgttctgtctcaccccatggctgtgaatgacaggacaggtcacacgtgtgttttccattgggtttaatttaatggacgtgcagtttcatttgtaaattgtgcattggccatctccttcagtggcaggatgtgagtggctacctggctcaactggaggggaccctcggggccctctggggcttcccctcccccacctggttggggtagagcaaaaggatggtcactcttccaaggtctccctgaaatgaatgtatttctccccccaaaagagctgatatttaatgttttaatagggatttttgagaaacaaataaccttatttataatctgggtgatccaatcattttttactcccttttgatgccatacatagaggaaagtctagcttttttggcgtgagacttttggaatgtgcagtgggataaaatgcgtttcctttaaaaaaaaaaaaaaaa

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