LOCUS       NM_001106303            1497 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus H6 family homeobox 2 (Hmx2), mRNA.
ACCESSION   NM_001106303 XM_001054069 XM_215056
VERSION     NM_001106303.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1497)
  AUTHORS   Zheng S, Damoiseaux R, Chen L and Black DL.
  TITLE     A broadly applicable high-throughput screening strategy identifies
            new regulators of Dlg4 (Psd-95) alternative splicing
  JOURNAL   Genome Res 23 (6), 998-1007 (2013)
   PUBMED   23636947
REFERENCE   2  (bases 1 to 1497)
  AUTHORS   Wang W, Grimmer JF, Van De Water TR and Lufkin T.
  TITLE     Hmx2 and Hmx3 homeobox genes direct development of the murine inner
            ear and hypothalamus and can be functionally replaced by Drosophila
            Hmx
  JOURNAL   Dev Cell 7 (3), 439-453 (2004)
   PUBMED   15363417
REFERENCE   3  (bases 1 to 1497)
  AUTHORS   Wang W, Chan EK, Baron S, Van de Water T and Lufkin T.
  TITLE     Hmx2 homeobox gene control of murine vestibular morphogenesis
  JOURNAL   Development 128 (24), 5017-5029 (2001)
   PUBMED   11748138
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_215056.2, XM_001054069.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM062017.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1497
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..1497
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /note="H6 family homeobox 2"
                     /db_xref="GeneID:293538"
                     /db_xref="RGD:1565366"
     exon            1..91
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /inference="alignment:Splign:2.1.0"
     exon            92..360
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..914
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /note="H6 homeo box 2"
                     /codon_start=1
                     /product="homeobox protein HMX2"
                     /protein_id="NP_001099773.1"
                     /db_xref="GeneID:293538"
                     /db_xref="RGD:1565366"
                     /translation="

MGSKEDVGKGCPAAGGVSSFTIQSILGGGPSEAPREPAGWPARKRSLSVSSEEEEPEEGWKAPACYCPDPHGPKEPSPKHHPPIPFPCLGTPKGSGGAGPAASERTPFLSPSHPDFKEEKERLLPAGSPSPGPERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVGMPLVFRDSSLLRVPVPRSLAFPAPLYYPSSNLSALPLYNLYNKLDY"

     misc_feature    order(540..554,558..560,609..611,627..629,666..668,
                     672..677,684..689,693..701,705..710)
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    546..707
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    order(546..548,555..557,675..677,684..689,696..698)
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     exon            361..1497
                     /gene="Hmx2"
                     /gene_synonym="RGD1565366"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggatatgtccccttggcaggccaaagtcagagaccacacttgcctgggaaactggaagtggagcctgggagaatgagaaggaggtgaaaaggatgggcagcaaggaagatgtggggaagggatgtccggcggccggtggcgtctccagcttcaccatccagtccatcctgggcgggggcccctccgaggcaccgcgggagcccgccgggtggccagccaggaaacgcagcttgtctgtgtcctcggaggaggaggagccggaggaaggctggaaggctccggcttgctactgcccagatccgcacggccccaaggagccaagccctaagcaccatccccccatccctttcccttgcctgggtacccccaagggcagcggaggcgcagggcctgcggcctcggagcgcacgcctttcctttctccttctcacccggactttaaggaagagaaggagaggctcttgcccgcaggctcgccttctccgggcccggagcggccacgggacggcggtgcagagcgccaagccggagcggccaagaagaagacgcgcaccgtcttctcccgcagccaagtgtaccagctcgagtccaccttcgacatgaaacgctaccttagcagctcggagcgcgcttgcctcgcctccagcctgcagctcaccgagacccaggttaagacttggtttcagaatcgccgcaacaagtggaagcgacagctttccgccgagctagaggcggccaacatggcacacgcgtcggcgcagactctcgtgggcatgccgttggtatttcgggacagttcgctactgcgagtgccggtgccacgctctctcgcctttccggctccgctctattaccccagcagcaatctctcggccttaccgctctacaacctgtacaacaagcttgactactgacacgcccgctggctcccggggcgcctctggtcgcctgcagttgcctgcatagtccggcgcggtcggtatccttactggggctccggagcagagcggcgcgtgtccagaaatattaagaaatacaccatgtgtattcgttatgtcttatttatggcctcttccctactttttgggttttttgttttgttttgagtatttatccgcattcctcacaccagagcacctgctttctacacaaaaccaaaccaacacgccacgcgtatgaaactattttggaaggggagattctcgggtagtggtgggaaagggggttttgattggccggtagcaagaaaaaaaacatcagaaaaataccaacaaaaccaggtagtctttctcccatatatacacctgtatatgtatataaatagtgtacaaggacacaatctcagccgagcggagcccactaggacgttggccattgaaccaatcacttctctttattcccttcatcttgaggatgagtaggggtgaaacgaggagagtacagatctgtaaatatttttaaagagaaaaaaaataaaacgttttaaacatggttgct

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