LOCUS       NM_001088485            1072 bp    mRNA    linear   VRT 24-SEP-2019
DEFINITION  Xenopus laevis VENT homeobox 3, gene 2 S homeolog (ventx3.2.S),
            mRNA.
ACCESSION   NM_001088485 NM_001088486
VERSION     NM_001088485.1
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
REFERENCE   1  (bases 1 to 1072)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev. Dyn. 225 (4), 384-391 (2002)
   PUBMED   12454917
REFERENCE   2  (bases 1 to 1072)
  AUTHORS   Shapira E, Marom1 K, Levy V, Yelin R and Fainsod A.
  TITLE     The Xvex-1 antimorph reveals the temporal competence for organizer
            formation and an early role for ventral homeobox genes
  JOURNAL   Mech. Dev. 90 (1), 77-87 (2000)
   PUBMED   10585564
REFERENCE   3  (bases 1 to 1072)
  AUTHORS   Shapira E, Marom K, Yelin R, Levy A and Fainsod A.
  TITLE     A role for the homeobox gene Xvex-1 as part of the BMP-4 ventral
            signaling pathway
  JOURNAL   Mech. Dev. 86 (1-2), 99-111 (1999)
   PUBMED   10446269
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF149307.1.
            On Jul 25, 2007 this sequence version replaced NM_001088486.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF149307.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN02908486, SAMN02908487
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1072
                     /organism="Xenopus laevis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8355"
                     /chromosome="7S"
     gene            1..1072
                     /gene="ventx3.2.S"
                     /gene_synonym="ventx3.2; vex1; xvex-1"
                     /note="VENT homeobox 3, gene 2 S homeolog"
                     /db_xref="GeneID:398140"
                     /db_xref="Xenbase:XB-GENE-864941"
     exon            1..307
                     /gene="ventx3.2.S"
                     /gene_synonym="ventx3.2; vex1; xvex-1"
                     /inference="alignment:Splign:2.0.8"
     misc_feature    37..39
                     /gene="ventx3.2.S"
                     /gene_synonym="ventx3.2; vex1; xvex-1"
                     /note="upstream in-frame stop codon"
     CDS             46..903
                     /gene="ventx3.2.S"
                     /gene_synonym="ventx3.2; vex1; xvex-1"
                     /note="ventral homeobox 1; homeodomain transcription
                     factor Xvex-1; ventral homeobox protein; homeodomain
                     transcription factor vex-1"
                     /codon_start=1
                     /product="homeobox protein vex1"
                     /protein_id="NP_001081954.1"
                     /db_xref="GeneID:398140"
                     /db_xref="Xenbase:XB-GENE-864941"
                     /translation="

MEKRPYSVEWLSESSQRKAVYSNADLLGYKSGNPDKESNISLPSRATGPTLPSVDYREKENYCVRNVQNEERSPPVKDQLHSQPAPQELDTSRRALMVVPACERSTDQGNKVTGTTDTNKKAKPVCDEDAAARARTKFSPEQLEELERSFKENRYIGSSEKRRLSKVLKLSETQIKTWFQNRRMKFKRQTQDARVDAFFSGLYVPYYGYPDLPTPGYSVQPEFSVLAPHTMAAPSLPFGPLQSTVISPGLHPTAIPSANLGSYPYSSMLVHPMLNEPKRQRYSPY"

     misc_feature    order(442..453,457..459,508..510,526..528,565..567,
                     571..576,583..588,592..600,604..609)
                     /gene="ventx3.2.S"
                     /gene_synonym="ventx3.2; vex1; xvex-1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(445..447,454..456,574..576,583..588,595..597)
                     /gene="ventx3.2.S"
                     /gene_synonym="ventx3.2; vex1; xvex-1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    448..606
                     /gene="ventx3.2.S"
                     /gene_synonym="ventx3.2; vex1; xvex-1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:278475"
     exon            308..567
                     /gene="ventx3.2.S"
                     /gene_synonym="ventx3.2; vex1; xvex-1"
                     /inference="alignment:Splign:2.0.8"
     exon            568..1061
                     /gene="ventx3.2.S"
                     /gene_synonym="ventx3.2; vex1; xvex-1"
                     /inference="alignment:Splign:2.0.8"
ORIGIN      

agtttgtggcagtttgtgaaagaggaaacacaaagttgaaggactatggagaagagaccctactcagtagaatggctttcagagagcagtcagaggaaagctgtttattccaatgcggatctattaggatataaaagtggaaatccagacaaggaatccaatatctcattgccatcaagagctactggaccaacattgccatcggtggactacagagagaaggaaaattattgcgtgcggaatgtccaaaatgaagaaagaagcccacctgttaaagaccaactgcactcccagccagcaccacaagagcttgatacatctagaagagccttaatggtggttcctgcttgtgagcgaagcactgatcaaggaaataaggtcactggcacaactgacaccaacaagaaggccaaacctgtgtgtgatgaagatgctgctgccagagcccgcaccaaattctcccctgagcagctggaggagcttgaaaggagcttcaaggagaacagatacattggatccagtgagaaaagacggctgtccaaggtgctgaaactctctgagactcagattaaaacctggtttcagaatcgaaggatgaagttcaagcgtcaaacgcaggatgcaagggttgatgctttcttttcgggactttatgtgccttattatggttaccctgaccttccaactcctggatattcagtccagccggagttttctgttctggcccctcatacaatggcagctccatctcttccatttggtcctctacaatctactgttatttcacctggactccacccaacagctattccttctgcaaaccttggctcttatccctactcttccatgcttgtacacccaatgctgaacgagcctaaacgacaaagatacagcccatactaaagtttcacattgtatacattgttgaagcaccactgttattattgttatggacatttgcaattatttattataagttattacatgaaagcacagcagcacattcagacagagttttattagtattgggttttttaataataaagaaatctgttctgttgaaaaaaaaaaa

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