LOCUS       NM_001085680             888 bp    mRNA    linear   VRT 22-MAY-2022
DEFINITION  Xenopus laevis ventral anterior homeobox 1 S homeolog (vax1.S),
            mRNA.
ACCESSION   NM_001085680
VERSION     NM_001085680.1
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
REFERENCE   1  (bases 1 to 888)
  AUTHORS   Hallonet M, Hollemann T, Wehr R, Jenkins NA, Copeland NG, Pieler T
            and Gruss P.
  TITLE     Vax1 is a novel homeobox-containing gene expressed in the
            developing anterior ventral forebrain
  JOURNAL   Development 125 (14), 2599-2610 (1998)
   PUBMED   9636075
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF064601.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF064601.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN04111048, SAMN04111062
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..888
                     /organism="Xenopus laevis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8355"
                     /chromosome="7S"
                     /map="7S"
     gene            1..888
                     /gene="vax1.S"
                     /gene_synonym="vax; vax1; vax1-a; vax1-b; vax1b; vax1b-a;
                     xvax1; xvax1b"
                     /note="ventral anterior homeobox 1 S homeolog"
                     /db_xref="GeneID:373698"
                     /db_xref="Xenbase:XB-GENE-6252856"
     CDS             1..888
                     /gene="vax1.S"
                     /gene_synonym="vax; vax1; vax1-a; vax1-b; vax1b; vax1b-a;
                     xvax1; xvax1b"
                     /note="homeobox protein"
                     /codon_start=1
                     /product="ventral anterior homeobox 1a"
                     /protein_id="NP_001079149.1"
                     /db_xref="GeneID:373698"
                     /db_xref="Xenbase:XB-GENE-6252856"
                     /translation="

MFEKTTDMDIRCNIEENGRISKPKDNKEIRETQAKMPSTYLKEQPGTYPAPGSSELCAKNKSSSAGDPEYCRRILVRDAKGSIREIILPKGLDLDRPKRSRTSFTAEQLYRLEMEFQRCQYVVGRERTDLSRQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPGLMPPCTTGTLRAPNSSGPGTRSLATVTSTPPHQPGLHPSPTGHNIFNMPVPSLLGTVANRLSSHPLTMAGNLHELSARYLSSSAFEPYSRSISKDSLDKKLLD"

     misc_feature    58..189
                     /gene="vax1.S"
                     /gene_synonym="vax; vax1; vax1-a; vax1-b; vax1b; vax1b-a;
                     xvax1; xvax1b"
                     /note="propagated from UniProtKB/Swiss-Prot (O93528.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    order(292..306,310..312,361..363,379..381,418..420,
                     424..429,436..441,445..453,457..462)
                     /gene="vax1.S"
                     /gene_synonym="vax; vax1; vax1-a; vax1-b; vax1b; vax1b-a;
                     xvax1; xvax1b"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    298..462
                     /gene="vax1.S"
                     /gene_synonym="vax; vax1; vax1-a; vax1-b; vax1b; vax1b-a;
                     xvax1; xvax1b"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:395001"
     misc_feature    order(298..300,307..309,427..429,436..441,448..450)
                     /gene="vax1.S"
                     /gene_synonym="vax; vax1; vax1-a; vax1-b; vax1b; vax1b-a;
                     xvax1; xvax1b"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    607..678
                     /gene="vax1.S"
                     /gene_synonym="vax; vax1; vax1-a; vax1-b; vax1b; vax1b-a;
                     xvax1; xvax1b"
                     /note="propagated from UniProtKB/Swiss-Prot (O93528.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     exon            1..232
                     /gene="vax1.S"
                     /gene_synonym="vax; vax1; vax1-a; vax1-b; vax1b; vax1b-a;
                     xvax1; xvax1b"
                     /inference="alignment:Splign:2.1.0"
     exon            233..420
                     /gene="vax1.S"
                     /gene_synonym="vax; vax1; vax1-a; vax1-b; vax1b; vax1b-a;
                     xvax1; xvax1b"
                     /inference="alignment:Splign:2.1.0"
     exon            421..888
                     /gene="vax1.S"
                     /gene_synonym="vax; vax1; vax1-a; vax1-b; vax1b; vax1b-a;
                     xvax1; xvax1b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

atgtttgagaagacaacagacatggacattaggtgcaacattgaggagaatggaaggatctccaaacccaaagacaacaaggagatcagagagactcaagccaaaatgccctcgacttacctgaaggagcagccgggaacttaccctgcgccgggctcgtctgaactttgcgccaagaacaagagcagcagcgctggggaccccgaatattgcaggaggattctagtgagagatgccaaaggttcaatccgggagatcattttacccaaagggctggatttggaccgacccaagcggagcagaacgtccttcactgcggagcaactgtaccggctggagatggagttccagagatgtcagtatgtggtcggccgagagagaaccgacttatcccgacagttaaatctctctgagactcaggtgaaggtctggttccagaaccgcagaaccaaacaaaagaaggaccagggaaaggactcggagctgcgctcggtcgtgtctgaaacggcagcaacttgcagtgtcctcaggctcctggaacagggtcgtctgctgtccccccccggcctgccaggactcatgcccccctgtacaactggcaccctccgtgcccccaatagctccgggcctggcaccagatcacttgcaactgtcaccagcacacccccccaccagcctggacttcacccttcccccactgggcacaacatcttcaacatgcccgtgccctccctactgggcaccgtggccaaccggctctcctctcacccactgacaatggccgggaacctgcacgaactctcggcccgatacctcagctcctcggcctttgagccctacagccggagcatcagcaaagactcactcgataaaaagctcctggactga

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