LOCUS       NM_001079399            3601 bp    mRNA    linear   VRT 23-DEC-2019
DEFINITION  Xenopus tropicalis NRDE-2, necessary for RNA interference, domain
            containing (nrde2), mRNA.
ACCESSION   NM_001079399
VERSION     NM_001079399.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 3601)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev. Dyn. 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC123943.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC123943.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3601
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="8"
                     /map="8"
     gene            1..3601
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing"
                     /db_xref="GeneID:780328"
                     /db_xref="Xenbase:XB-GENE-960400"
     exon            1..116
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    8..10
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /note="upstream in-frame stop codon"
     CDS             53..3466
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2"
                     /protein_id="NP_001072867.1"
                     /db_xref="GeneID:780328"
                     /db_xref="Xenbase:XB-GENE-960400"
                     /translation="

MALFPAFADSSSSSKKSPSRQELDWLSNKSFCTEDALSLHQRALQSAQFPQPACHSPRSPFQQELFEESGSDSQATKKKKKKKKKKKQKKKHKQKRGYDEDEEGNTSDSDSRPETRESKETESVARQDTCVVLPGRGIWLDEVQSVTEETYRIDKKSDPANWEYKSLYQGDIARYKRKGNSCLGINPKKQQINWQDALSEKKEARRKNERYFTKSTMQLLSANADFVSCKESASLKSGEFIPVLDPDKDGVISSSGPISWVNPLGVYDSSTALWLEGKGGPEYDTIQPVPRDNNILAKVEDYNKRIRECPNDIQLWMEFVSFQDELVKQPSMYSTSKGELDGHRTSVKLLLEKKLAILERAIESNPGSTELKLAKLKLCEEFWEAPTLLKEWQKLIFLHPNDSQLWQKYLLFCQGQFSTFSVSKMNSIYGKCLSTLAAVQDGIMLSHNALPDTESNMYDIFLQQCQFLRQAGHTEKVISLFQALTDFTFYKPDSVKDMTTKEQVDFFEPFWDSGEPRFGEKGAKGWSSWMRQQERGGWIIINNLVEDDEDEADEELSIRGKNCPRYKIWLDVECSREARHWLPWRPDTTKKQTEDECEDPERQVLFDDIGPSMFKITSPQMQFQLFKSFLHFLGVPCGANISPRCFYLALDETSIFDHVSPYEMLLNSFEIPLSGIGTVGHLDTLSRSRQQIGYFKEGETFIQNIFQSALSLLHGEEKRNISVWWLQYEISKVVWCLQANNKKKLRSQGKRSKRLAKSLLKEASNRNSLALWKEYALLEWLLGNIDDARKVFDTAISLAGSKGLKDQELCSLCLLYSELEGKLLDNPEENAGSRAVHILTSLTESSPYTPYNSPEHAISILKARKVYEHAMQDCLRQQPHWGRVSLSGCFALFQYLTVSVDAAVVVLRQAADIPMTPETLDNVAQNASSPLQAITLMHTNLLRHHYKVSVYPLSPLRDILMSALKTYPCNVSLWKSYIRTEGKLHNASRVRRFIDSIRRMTPALEPCLFAIRAEEDRKKIVESVQRPDQGEVHSIFPETGLSNRIKALFEYALQSEYGSRCPLLWRLYLHFMVSLGNKERSKGLFYKAIQSCPWAKALYLDAVEYFPEQLQETIDLMTEKELRVRVPLEELDLLLED"

     misc_feature    500..787
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(500..526,533..538,548..553,557..559,563..607,
                     614..622,626..634,656..664,674..679,683..688,695..712,
                     737..748,758..787)
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    956..1954
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:429988"
     exon            117..225
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            226..429
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            430..573
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            574..1021
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1427
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1561
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            1562..1685
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1861
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            1862..2248
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            2249..3129
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            3130..3268
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            3269..3340
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
     exon            3341..3590
                     /gene="nrde2"
                     /gene_synonym="c14orf102"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gaaacgttgacgtcttttgaatgcgacgcgtttgttgacaagtacaggagtaatggctctatttccagcctttgcagactcttctagttctagtaagaaatctccttcacgccaagagttggactggctgagcaacaagagcttctgcacagaagacgctctttcactacaccagcgtgctttgcagtctgcacaatttcctcaacctgcatgccactcacccaggagtccatttcagcaagagctgtttgaagaaagtggatctgattctcaggcaacaaagaagaagaagaaaaagaaaaaaaaaaagaaacagaaaaaaaagcacaagcaaaagaggggttatgatgaggatgaagaagggaatacaagtgactctgactcaaggcctgagacaagggaatctaaagagactgaaagtgtggcaaggcaggacacttgtgttgtgctccctggccgtggtatctggctagatgaagtgcagtctgtgacagaggagacatatcgaattgataagaaatctgaccctgccaactgggaatataagtcactgtaccaaggagacatagcacggtacaaacggaaaggaaattcctgtctgggcatcaatccaaagaagcagcaaattaattggcaggacgcattatctgagaagaaagaagcacgcaggaaaaatgagcgttattttaccaagagcacaatgcagcttctcagtgccaatgcagattttgtgtcttgtaaggaaagtgcaagtctgaaatcaggggaatttattcctgtgttagatcctgataaggatggtgttatttcctccagtggccctattagctgggtgaatcctttgggagtgtatgattcttctacagctctgtggttggaaggaaaagggggtccagaatatgatactatacagccagtaccccgggacaacaatattttggcaaaggtggaggattataacaagcggatcagagaatgccctaacgatatccaactatggatggagtttgtctcttttcaggatgagttggtgaagcagcccagcatgtattctaccagcaaaggagagcttgatggccatcggacatctgtgaagctgctactggagaaaaaactagctatactagaaagagccattgagagtaatccgggcagcactgaattaaagcttgcaaagctaaagctctgtgaggaattctgggaggcacccactcttctcaaggaatggcagaaactgatcttcttgcacccaaatgactcgcagctgtggcagaaatatctgctcttctgccagggtcagtttagcactttctctgtgtccaagatgaacagtatttatggcaaatgcctaagcacactggcagcagttcaggatggtattatgctttcccacaatgctctgccagacacagagagcaacatgtatgatatttttctgcaacagtgccagttcttacgccaggctggacacacagagaaagtaatatccttattccaagctcttactgacttcacattttataaaccggacagtgttaaggatatgacaaccaaagagcaggttgacttttttgagcctttttgggacagtggggaacctcgttttggtgagaaaggagcaaagggatggagctcctggatgcgccaacaggagagagggggctggatcatcattaacaatttggtggaggatgatgaagacgaagcagatgaagagttaagcataagaggcaaaaactgtcccagatacaagatttggttggatgttgaatgctcaagggaagcaaggcactggttgccatggcgtccagacaccacaaaaaagcagacagaggatgaatgtgaggatccagagaggcaggttctttttgatgatattggcccgtcaatgttcaagatcaccagtcctcaaatgcagttccagctctttaaatcattcctgcattttcttggggtcccctgtggggctaacatttccccacgctgcttttaccttgctcttgatgagacctccatctttgatcatgtttctccttatgaaatgctgcttaactcgtttgaaatccctctgtctggaatcggtacagttggtcatttagacacattaagcagaagcaggcaacaaataggatactttaaagaaggggaaaccttcatacaaaatatctttcagtcagctctgtcacttttacatggagaagagaagaggaacatctcagtttggtggcttcagtatgaaatttcaaaggttgtttggtgcctgcaagcaaataacaagaaaaagctgagatctcagggcaagaggagcaagcgattggcaaagagcctactgaaggaagcatcaaacagaaacagtctggcactctggaaggaatatgctcttctagaatggcttctgggcaatattgatgatgcccgaaaggtgtttgatacagccataagcttagcaggaagcaaagggttaaaggaccaggaattatgcagtttgtgtctgctgtattcagaactggaagggaagctactggacaatccagaggaaaatgcggggtcccgtgctgttcatatacttaccagccttacagaaagctctccttacactccctataatagccctgagcatgctattagtattctgaaagcacgcaaagtatatgaacacgccatgcaggactgcctgaggcaacagccacattgggggcgtgttagcttatctggatgctttgcactttttcagtatctaactgtgagcgttgatgctgctgttgtggtattaagacaggctgctgacatcccaatgactcctgaaacattggacaatgttgctcagaacgccagcagcccattgcaagcaattacactgatgcacacaaatctgctcagacaccattataaggtcagtgtctatcctctgagtccacttagagacatactgatgtctgccttaaagacatatccctgcaatgtttctctgtggaaatcctacatcagaactgaaggtaaattacacaatgccagcagggtgagaaggtttatagacagtatcaggagaatgacaccagctctggaaccatgtctgttcgccatcagagcagaggaggacagaaaaaaaatagtagaatctgtacaaaggccagatcaaggggaggttcactctattttccctgaaactggtttgtccaatcgaatcaaggccctttttgaatatgctcttcaaagtgaatatggttccaggtgccctctgctctggaggctgtacttgcactttatggtgtctttgggaaacaaggagagaagcaaaggcctgttctacaaagcaatacagagctgcccatgggcaaaggcactatacttggatgctgtagaatatttcccggagcagctgcaagagaccattgatctaatgactgaaaaggagctgagagtacgagttcccctagaggaactggatctgctgctggaagattaaaccacagaattattgaattgtttcccttctgggcaacatctctaaagcaacaaacttgtacaatacattttataatatatatttatttttaaggaaaaacaataaaatacatccacacccaaaaaaaaaaaaaaa

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