LOCUS       NM_001078629            2562 bp    mRNA    linear   VRT 26-JUN-2020
DEFINITION  Takifugu rubripes taste receptor, type 1, member 3 (tas1r3), mRNA.
ACCESSION   NM_001078629
VERSION     NM_001078629.1
KEYWORDS    RefSeq.
SOURCE      Takifugu rubripes (Fugu rubripes)
  ORGANISM  Takifugu rubripes
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Eupercaria; Tetraodontiformes; Tetradontoidea;
            Tetraodontidae; Takifugu.
REFERENCE   1  (bases 1 to 2562)
  AUTHORS   Ishimaru Y, Okada S, Naito H, Nagai T, Yasuoka A, Matsumoto I and
            Abe K.
  TITLE     Two families of candidate taste receptors in fishes
  JOURNAL   Mech. Dev. 122 (12), 1310-1321 (2005)
   PUBMED   16274966
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB200913.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB200913.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06130151 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2562
                     /organism="Takifugu rubripes"
                     /mol_type="mRNA"
                     /db_xref="taxon:31033"
                     /chromosome="19"
                     /map="19"
     gene            1..2562
                     /gene="tas1r3"
                     /note="taste receptor, type 1, member 3"
                     /db_xref="GeneID:778008"
     CDS             1..2562
                     /gene="tas1r3"
                     /codon_start=1
                     /product="taste receptor, type 1, member 3 precursor"
                     /protein_id="NP_001072097.1"
                     /db_xref="GeneID:778008"
                     /translation="

MAVSPTLLVLFWVFKMTSATPAWFQNISTSLFNLPGDIKLGGLFPLNRLTSNLSQRTEPDQISCDRINTYGLGMAIAMKYTVDEINANQILLPGIQLGYEIYDTCLQSAIIVRPTLSLLSAKHDNTFSVQCNYTNYETSISAVIGPNNSEMVSVIGKLLGFFLMPQISYGATSEKFSDTALYPSFFRTVPSDKWQVEAMVLLLEEFNWNWVAVVGSDEEYGQRGVQDFSKLAANKSICVAYQGLIPVYTDPEPMVKTILSNINSTKARVVIVFSLSNQAEIFFKEVIRMKLKGVWIGSTSWTINDAVTSLPDIQTGWTILGFVEQTQSVDLLRAYTYALLNKLSEERAHTRSSAQNSNYPSNPCPQCWNLSPANISLVTDLVIQRKAFSVYAAIYSVAQALHNFLQCNSTACKNTSEVKIYPWKLLKTLRHTKVDINGTMLEFDSNGNPNVGYNLIELIWKNSTLEFVEVGSFNKILNINVSLFKWHTETSEVPQSTCSAACGEGQVHRVKGFHSCCFDCIDCLPGTYQAQDGDIQCTPCPPRQWSLARSSRCTDPIYDYLSWDTPEALLLTLAIVLVVLFMGSVVVVFVNHRETVLVTASGGTLSIVVLLGLMGACLSLLLFLGQPGDTVCRLQLPLISAFQTVPLSIIMSISLQIFFVSEFPNLAASYLHVLRGPGTWLLLLTCCAVQAGICGWFVQDGPSLSEYLADRRVDFVRSFLACPVSPLSGFALMQGFSAAMALMSFMCTFMATKPLHQYNLARDITFSSLIYCVIWVTFIPIYIGLEEKRRAIIHVSFILASDLGLVAVYYIPKCYFLLKTPELNTADHFCTFLEGLQPTPAQEEPQTQTESEQ"

     sig_peptide     1..57
                     /gene="tas1r3"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     misc_feature    94..1482
                     /gene="tas1r3"
                     /note="ligand-binding domain of the T1R taste receptor;
                     Region: PBP1_taste_receptor; cd06363"
                     /db_xref="CDD:380586"
     misc_feature    order(325..330,334..339,346..351,358..360,391..393,
                     460..462,469..471,481..486,676..678)
                     /gene="tas1r3"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:380586"
     misc_feature    order(439..441,508..516,658..660,898..900)
                     /gene="tas1r3"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:380586"
     misc_feature    1480..1638
                     /gene="tas1r3"
                     /note="Nine Cysteines Domain of family 3 GPCR; Region:
                     NCD3G; pfam07562"
                     /db_xref="CDD:429539"
     misc_feature    1696..2457
                     /gene="tas1r3"
                     /note="type 1 taste receptor subtype 3, member of the
                     class C of seven-transmembrane G protein-coupled
                     receptors; Region: 7tmC_TAS1R3; cd15290"
                     /db_xref="CDD:320417"
     misc_feature    1696..1773
                     /gene="tas1r3"
                     /note="TM helix 1 [structural motif]; Region: TM helix 1"
                     /db_xref="CDD:320417"
     misc_feature    order(1705..1707,1714..1719,1726..1731,1735..1740,
                     1840..1842,1852..1854,1861..1866,1888..1890,1900..1902)
                     /gene="tas1r3"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:320417"
     misc_feature    1807..1872
                     /gene="tas1r3"
                     /note="TM helix 2 [structural motif]; Region: TM helix 2"
                     /db_xref="CDD:320417"
     misc_feature    order(1867..1869,1903..1908,1915..1920,1927..1929,
                     2173..2175,2188..2190,2197..2202,2209..2211,2311..2313,
                     2320..2325,2332..2334,2344..2346,2368..2373,2380..2382,
                     2389..2391,2401..2403)
                     /gene="tas1r3"
                     /note="putative allosteric modulator binding site
                     [chemical binding]; other site"
                     /db_xref="CDD:320417"
     misc_feature    1897..1971
                     /gene="tas1r3"
                     /note="TM helix 3 [structural motif]; Region: TM helix 3"
                     /db_xref="CDD:320417"
     misc_feature    2035..2097
                     /gene="tas1r3"
                     /note="TM helix 4 [structural motif]; Region: TM helix 4"
                     /db_xref="CDD:320417"
     misc_feature    2176..2256
                     /gene="tas1r3"
                     /note="TM helix 5 [structural motif]; Region: TM helix 5"
                     /db_xref="CDD:320417"
     misc_feature    2278..2349
                     /gene="tas1r3"
                     /note="TM helix 6 [structural motif]; Region: TM helix 6"
                     /db_xref="CDD:320417"
     misc_feature    2362..2439
                     /gene="tas1r3"
                     /note="TM helix 7 [structural motif]; Region: TM helix 7"
                     /db_xref="CDD:320417"
     exon            1..197
                     /gene="tas1r3"
                     /inference="alignment:Splign:2.1.0"
     exon            198..498
                     /gene="tas1r3"
                     /inference="alignment:Splign:2.1.0"
     exon            499..855
                     /gene="tas1r3"
                     /inference="alignment:Splign:2.1.0"
     exon            856..1272
                     /gene="tas1r3"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1476
                     /gene="tas1r3"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1597
                     /gene="tas1r3"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..1968
                     /gene="tas1r3"
                     /inference="alignment:Splign:2.1.0"
     exon            1969..2562
                     /gene="tas1r3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

atggccgtatctcccactctgctggttttattctgggtttttaagatgaccagtgctactccggcgtggttccaaaacatctcgaccagtctcttcaacttgcctggagatatcaagcttggggggcttttccccctcaaccggctcactagcaacctcagccagaggacggagccagaccaaatcagctgtgacaggataaacacatacggactgggcatggctatcgccatgaaatacacagtggatgaaatcaatgccaaccaaattctgctgcccggaatccagttgggttatgaaatctatgacacctgtctccagtcagccatcatcgtcagaccaaccctctcactcctctctgcaaaacatgacaacactttcagcgtgcagtgtaattacaccaactatgagaccagcatatcagctgtgattggacccaacaactcagaaatggtgtcagtcatagggaaacttctaggattcttcctgatgccacagataagctatggtgccacaagtgaaaaattcagcgatactgctctctacccatcattcttccggacggtgcccagtgataaatggcaggtcgaagccatggttcttctgctggaggagttcaactggaactgggtggctgtggtgggcagtgatgaggagtatggacagcgaggagtgcaggacttctccaaactagcagcaaataagtccatttgtgtggcatatcaggggttaattccagtctacacagacccggaaccaatggttaaaaccatcctcagtaatatcaactcaactaaagcccgcgtagtgattgtgttttctctctcaaaccaggcagaaatctttttcaaagaggtcatcagaatgaaactaaaaggggtgtggattggcagcacaagctggaccataaatgatgctgtcacctctctccccgacatccaaacgggttggaccatcctgggatttgtcgaacaaacacaaagtgtggaccttctccgtgcctacacgtacgcactcttaaacaaactgagtgaagagcgtgcacacacacgctcttcggcacaaaactccaattatccttccaatccgtgcccacaatgctggaacttgtcacctgctaatattagcttggtgacggaccttgtgatacaacgcaaagcctttagtgtctatgctgccatctacagtgtagcacaggcactgcacaattttctgcaatgcaattcgactgcatgtaaaaatacgtctgaagtcaaaatctatccctggaagctgctgaagactctgagacacacaaaagtggacataaatggcacaatgttagagtttgacagcaatggcaacccaaatgttggatacaatttgattgagttgatctggaaaaattcaacactggaatttgtagaggttggaagcttcaataagattttgaacatcaacgtgtccctgttcaaatggcacactgaaacctcagaggttcctcagtccacctgttcagcagcgtgtggagaaggccaggtccacagagtcaaaggattccattcctgctgctttgattgtattgactgtttaccaggaacctaccaggcacaagacggggacattcagtgcaccccatgtcctccccgtcagtggtctctggcacgcagctccaggtgcaccgaccccatctatgactacttgtcctgggacacaccagaagctttactactgactctggctatagtgctggtcgtactattcatggggtcagtggttgtggtcttcgtgaaccacagggagacggtgctggtgactgcttcaggggggactctgagtattgtggttctgctcggtctgatgggagcttgtctcagtctgctgctgttcctgggacaaccaggggacacggtgtgtcgtctccagctgcccctcatttctgccttccaaacagtgcccctctccattatcatgtccatttctctgcagattttctttgtgtcagaattcccaaacttagcagcctcttacctgcatgtactcagaggtcctggaacgtggctgctcctgctgacctgttgtgctgtgcaggccggcatctgtggctggtttgtccaggacggaccgtctctgtctgaatatctggcagacaggagggtggactttgtgagatcctttctggcttgtccagtgtcgcctttgtctggctttgccctcatgcaaggtttcagtgctgccatggcgctcatgtcattcatgtgcaccttcatggcaacaaaacctcttcatcagtacaacctggcgagggacatcaccttttcctccctcatctactgtgtcatttgggtgacctttattccaatctacatcggtctggaggaaaaacgcagggcaattattcatgtttcctttatcctagcaagcgacctgggtctggtggcggtgtactacatcccaaaatgttacttcctgttgaaaacacctgagctcaatactgcagatcacttctgtacctttctggaaggtctccaaccaacaccagctcaagaggaaccacagacccagacagagtcagagcaatag

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