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2022-01-26 16:57:37, GGRNA.v2 : RefSeq release 209 (Nov, 2021)

LOCUS       NM_001013611            2578 bp    mRNA    linear   VRT 26-APR-2021
DEFINITION  Gallus gallus claudin 1 (CLDN1), mRNA.
ACCESSION   NM_001013611 XM_422720
VERSION     NM_001013611.2
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 2578)
  AUTHORS   Fishwick KJ, Neiderer TE, Jhingory S, Bronner ME and Taneyhill LA.
  TITLE     The tight junction protein claudin-1 influences cranial neural
            crest cell emigration
  JOURNAL   Mech. Dev. 129 (9-12), 275-283 (2012)
   PUBMED   22771518
  REMARK    GeneRIF: Claudin-1 is highly expressed in the developing
            neuroepithelium.
REFERENCE   2  (bases 1 to 2578)
  AUTHORS   Zhang B, Shao Y, Liu D, Yin P, Guo Y and Yuan J.
  TITLE     Zinc prevents Salmonella enterica serovar Typhimurium-induced loss
            of intestinal mucosal barrier function in broiler chickens
  JOURNAL   Avian Pathol. 41 (4), 361-367 (2012)
   PUBMED   22834550
  REMARK    GeneRIF: Dietary Zn supplementation appeared to alleviate the loss
            of intestinal mucosal barrier function induced by S. Typhimurium
            challenge and the partial mechanism might be related to the
            increased expression of occludin and claudin-1 in broiler chickens.
REFERENCE   3  (bases 1 to 2578)
  AUTHORS   Simard A, Di Pietro E, Young CR, Plaza S and Ryan AK.
  TITLE     Alterations in heart looping induced by overexpression of the tight
            junction protein Claudin-1 are dependent on its C-terminal
            cytoplasmic tail
  JOURNAL   Mech. Dev. 123 (3), 210-227 (2006)
   PUBMED   16500087
  REMARK    GeneRIF: Taken together, our data provide evidence that appropriate
            expression of the tight junction protein Claudin-1 is required for
            normal heart looping and suggest that phosphorylation of its
            cytoplasmic tail is responsible for mediating this function.
REFERENCE   4  (bases 1 to 2578)
  AUTHORS   Simard A, Di Pietro E and Ryan AK.
  TITLE     Gene expression pattern of Claudin-1 during chick embryogenesis
  JOURNAL   Gene Expr. Patterns 5 (4), 553-560 (2005)
   PUBMED   15749086
  REMARK    GeneRIF: Tissues that expressed significant levels of claudin-1
            were epithelialized in chick embryo.
REFERENCE   5  (bases 1 to 2578)
  AUTHORS   Caldwell RB, Kierzek AM, Arakawa H, Bezzubov Y, Zaim J, Fiedler P,
            Kutter S, Blagodatski A, Kostovska D, Koter M, Plachy J, Carninci
            P, Hayashizaki Y and Buerstedde JM.
  TITLE     Full-length cDNAs from chicken bursal lymphocytes to facilitate
            gene function analysis
  JOURNAL   Genome Biol. 6 (1), R6 (2005)
   PUBMED   15642098
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ719422.1.
            On Apr 3, 2005 this sequence version replaced NM_001013611.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ719422.1, BU375537.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA103992290, SAMEA103992323
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2578
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="9"
                     /map="9"
                     /breed="Leghorn"
     gene            1..2578
                     /gene="CLDN1"
                     /note="claudin 1"
                     /db_xref="CGNC:66478"
                     /db_xref="GeneID:424910"
     exon            1..301
                     /gene="CLDN1"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..714
                     /gene="CLDN1"
                     /note="tight junction protein"
                     /codon_start=1
                     /product="claudin-1"
                     /protein_id="NP_001013629.1"
                     /db_xref="CGNC:66478"
                     /db_xref="GeneID:424910"
                     /translation="
MASGGLQLLGFVLAFLGWMGIIISTAMPQWKMASYAGDNIVTAQALYEGLWMSCAMQSTGQIQCKVYDSLLKLEGSLQATRALMVAAILLGLVGVFVAVTGMKCMKCMEDDQVKKMRMAVFGGVIFIIAGLSALVATSWYGNRVARAFYDPFTPVNTRFEFGSALFIGWAAASLALLGGAFLCCSCPRSETSYPPSRGYPKNAPSTGKDYV"
     misc_feature    91..624
                     /gene="CLDN1"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:304458"
     exon            302..466
                     /gene="CLDN1"
                     /inference="alignment:Splign:2.1.0"
     exon            467..551
                     /gene="CLDN1"
                     /inference="alignment:Splign:2.1.0"
     exon            552..2566
                     /gene="CLDN1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
gtcagtgcgctgttggttgtgctcccgtgtttttcatcgcagccaacctccgcaggtgcggagcagccccgcgcagccatggccagcgggggcttgcagctcctgggcttcgtgctggccttcctcggctggatgggtatcatcatcagcaccgccatgccccagtggaagatggcatcgtacgcgggggacaacatcgtgacggcccaggcgctctacgaggggctgtggatgtcgtgcgccatgcagagcacggggcagatccagtgcaaggtgtacgactcgctgcttaagctggagggcagcctgcaggccacacgggccttgatggtggccgccatactcctgggtctggttggtgtgtttgttgctgtgacgggcatgaagtgcatgaagtgcatggaggatgaccaggtgaagaagatgcggatggctgtctttggtggcgtgatcttcatcattgcaggtctgtcagcactggtggccacgtcatggtatggcaacagagtggctcgggccttctatgaccctttcacacccgttaacaccagatttgagtttggatcagccctcttcattggctgggcagccgcttctctggcattgctggggggagcattcctctgctgctcctgcccccggagtgaaacatcctacccacccagccgaggctaccccaaaaatgccccctccacagggaaggattacgtataatgaaatgacaaagaggagccaccagcactggtagtagaagcatttggagaggacactacaatgccgctgtcctgagcagagttcagactctaggttttgccttcctcttatcccagaaatgtgtatatttttgtaatcctctttgctactggacataacttctcctttctctcccagcccgtggaggaaggctagcctaagcttgtaggtatcgccactggaaagattgaagcctccaagcttgggttaagtttagtatttgggagtaaaagggaaaatgatactgtttttagatggatgttggtgctttttttagtttttttattaaaaatagatggtaacaattcagtccccatatcccattaagttagagcccggcgtggtgtgtgtagaaatcaaagaaacactatatacaaagagaagaccaatagcttaaggggaaacataattttggggaaatgactttacaggtaggaatgtttgaagagatctaaactgtttttatactgttactggtgtcatcttcagcaccttcctttccgtgcaaagggtcagatgaaattaaattgctgtgacttaaactaaaatctgtaactgtatgcatgcgctgttggccaacagaagatgtagcgtaagacagcctggcttaactgagtgtcatcttttgacaagatctggtaagatgattgtgttacagcccttggccaatacattacagctacaacggctagcaaactcccaagcagctgcatatctccctggtgccagggaagaggtagacagaaacaatccccagttctcactgttgtctctagggctgctgcattgttccttagacactgttgctggtggttgtttcttggtgttcttagcctgactgagctcaaagctatatccccccttgtcagttacaggtcaccttttaacaagtgttgccctctctccttgagtcattccagtttgggcttagttataagttactgatctgtttgccttatgtggctaaaaaatgttaaaccaaacaatgcactgccactccctgatgtttccccatggatacctcttgtactgtcatttgaccctatctttactcttgcaaatactttcagtcatgatatgaaggcaaattccaaggaaactgacccaaaggttatagcattttctttcaatccaagctcaccaaagagggaagaaacccagcactgtaaagataaagccatcattgcatattaagtcctatatgaaaatgcagctcatgggttcccacgttttcccctgaaaccagtctgtcaccggtgtctgaccaacactggtgaggctggctggagattagtctggtgttctgaaggaggatgatatcagctttccaaggctcagctttgatttgtctaaggacagaagctgattgcttccaaccaggctttatgatggtgaatgtgttcagaggcatcaggtatctgggtttcttctgtagacaaggagagccgtgtgcacccacagcctaagtgcttcatataagccttgtacctctgtttgacctgactctgcaatgtaaatcaaagctactaaagaaaccaaccaaagcatttgcttcaggcttgatctgatgctgacctgtacttgagctgggtcacatggctcctacttctcgatggggaattgccccgtgcacagtggggccttatgagaccttgtaccttgtcttaaggggtggcagctcaggtcacactaaagagctgctgaggtctgtgcttttgtatttgcattaaccctgtgccagggagcagatgcttgtattgggaacttgtataaagtgtttaaacaatttcaataaatggatttttgtaaggaaaaaaaaaaaaaa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]