LOCUS       XM_078335608            3711 bp    mRNA    linear   PRI 01-JAN-2026
DEFINITION  PREDICTED: Callithrix jacchus NRDE-2, necessary for RNA
            interference, domain containing (NRDE2), transcript variant X5,
            mRNA.
ACCESSION   XM_078335608
VERSION     XM_078335608.1
DBLINK      BioProject: PRJNA1262967
KEYWORDS    RefSeq.
SOURCE      Callithrix jacchus (white-tufted-ear marmoset)
  ORGANISM  Callithrix jacchus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_133509) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_049354715.1-RS_2025_12
            Annotation Pipeline         :: NCBI Eukaryotic Genome Annotation
                                           Pipeline (EGAP)
            Annotation Software Version :: 10.5
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/15/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3711
                     /organism="Callithrix jacchus"
                     /mol_type="mRNA"
                     /isolate="240"
                     /db_xref="taxon:9483"
                     /chromosome="8"
                     /sex="male"
                     /tissue_type="fibroblast cell line"
                     /geo_loc_name="USA: Pittsburgh"
                     /collection_date="2023-08-31"
     gene            1..3711
                     /gene="NRDE2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 802 long SRA reads, 3 Proteins,
                     and 100% coverage of the annotated genomic feature by
                     RNAseq alignments, including 68 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:100389090"
     misc_feature    1
                     /gene="NRDE2"
                     /experiment="COORDINATES: cap analysis [ECO:0007248]"
                     /note="transcription start site"
     CDS             622..3435
                     /gene="NRDE2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2 isoform X4"
                     /protein_id="XP_078191734.1"
                     /db_xref="GeneID:100389090"
                     /translation="

MNIDGIAISSKTEPPSSDPASFIPVKDLEDAAPVTTWLNPLGIYDQSTTQWLQGQGPPEQESKQPDTQPDSESAALKARVEEFNRRVRENPRDTQLWMAFVAFQDEVMKSPGLYAIEEGEQEKRKRSLKLILEKKLAILERAIESNQSSVDLKLAKLKLCTEFWEPSTLVKEWQKLIFLHPNNTALWQKYLLFCQSQFSTFSISKIHSLYGKCLSTLSAVKDGSILSHPALPGTEEAMFALFLQQCHFLRQAGHSEKAISLFQAMVDFTFFKPDSLKEMPTKGQVEFFEPFWDSGEPRAGEKGARGWKAWMHQQERGGWVVISPDEDDEEPEEDDQEIKDKTLPRWQIWLAAERSRDQRHWRPWRPDKTKKQTEEDCEDPERQVLFDDIGQSLIRLSSEDLQFQLVVAFLQFLGVPSGFTLPASCLYLAMDEHSIFDNGLYDEKPLTFFNPLFSGASCVGRMDRLGCPRWTRGQNREGEEFIRNVFHLVMPLFSGKEKSQLCFSWLQYEIGKVVWCLHTKNKKRLKSQGKNCKKLAKNLLKEPENRNNFCLWKQYAHLEWLLGNTEDARKVFDTALGMAGSQGLKDSELCELSLLYAKLEVELEVELSPEVRGAASARAVHILTKLTESSPYGPYTGQVLAVHILKARKAYEHALQDYLGDSCVSDPAPTDSCTRLISLSKCFMLFQYLTVGIGAAVRIYEQVFAKLHSSVFPEGSGEGNSASSQSRSSFLEAITLMHASLLRFHMKVSVYPLAPLREALSQALKLYPGNQVLWRSYVQIQNKSHSASKTRRFFDTITRSAKPLEPWLFAIEAEKMRKRLVETVQRLDGREIHATIPETGLTHRIQALFENAMRSDSGSQCPLLWRMYLNFLVSLGNKERSKGVFYKALQNCPWAKVLYLDAVEYFPEEMQEVLDLMTEKELRVRLPLEELELLLED"

     misc_feature    865..1863
                     /gene="NRDE2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
     polyA_site      3711
                     /gene="NRDE2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

atttctgtagcgaggaacggcggtgcggcctgtggtcatggcgctgttcccggcctttgcgggcgttagcgaggcccccgatagtgggagctccaggaaaggagtcctctgaaatcagagccttcagatgaaagtgacactaacaaaaagctcaaacaaacaagcagaaaaaagaagaaagagaaaaagaaaagaaggaagcatcagcatcataagaaaacaaagaggaaacatggacagtcgagtagcagtaggtcggagacagacactgattctgaaaaggacagaccttccagagccatcggaggccgtaaaaaggaatctgagaaaccgaatcaaggaaataatgcggcagctgatactggacatcgctttgtttggcttgaggacattcaggctgtgacaggagaaaccttcagaacagataagaaaccagatcctgcgaactgggaatacaagtctctctaccgaggggatatagcaagatacaagaggaaaggagactcctgccttggcattaatcctgtgaagcaacgcatatcttgggaagggacttccacagagaagaagcattcacgcaagcaggttgaacgctattttactaagaagagtgtggggttaatgaacattgatggaattgccattagcagtaaaactgaacctccatcatctgaccccgcctcctttataccagtgaaggacttggaagatgcagctcctgttacaacctggttgaatcctctggggatttatgatcagtcaaccacacagtggctacaaggacagggtcctccagagcaggaatcaaagcagccagacacacagccagacagcgagagtgcagctctcaaggccagggtggaggagtttaacaggagggtgcgggagaatccgcgggatacgcagctgtggatggcatttgttgcttttcaggacgaggtcatgaaaagtcctgggctgtatgccatcgaggaaggagagcaggaaaagcgaaagcggtccctgaagctcattctggagaagaagctggccatcctggagcgggccattgagagcaaccagagcagtgtggatctgaaactggccaagctgaagctctgcacagagttctgggagccctccactctggtcaaagagtggcagaaactgatatttttacatcccaataatacagccctgtggcagaaataccttttgttttgccagagccagtttagtaccttttcgatatcaaaaattcacagtctttatggaaaatgcttgagtactttgtctgctgttaaggacggcagcatcttatctcaccctgcgttgcctggcacagaagaggccatgtttgcactctttcttcagcagtgccactttctgcggcaggccggccactctgagaaggccatctcattgttccaggccatggtggacttcaccttcttcaaacctgacagcctgaaagagatgcctaccaaaggacaggtggaattctttgagcccttttgggacagtggagagccccgggctggggaaaagggagcccgaggatggaaggcgtggatgcaccagcaggagcgaggtggctgggtggtcatcagcccagacgaggatgacgaagaaccagaagaggacgaccaggaaataaaagataagactctgcccaggtggcagatctggcttgctgctgagcgttcccgagaccagaggcactggcggccctggcgccctgataagaccaagaagcaaacggaggaagactgtgaggatcccgagagacaggtgctgtttgatgatatcgggcagtctttgatcagactctccagcgaagacctgcagttccagctggtggtggcctttctgcagttcttgggtgtgccttccggcttcactctgccagcctcctgtctttatctggccatggatgagcacagcatctttgataatggactttatgatgaaaagcccttgacttttttcaaccctttgttttccggggccagctgtgtgggccgcatggaccggctgggctgtcctcgctggaccaggggtcagaaccgagagggcgaggagttcatccgcaacgtcttccacctggtcatgcctttgttttcaggcaaagagaagtctcagctctgcttctcctggttacagtatgagattggaaaggtcgtgtggtgtctgcacactaaaaacaagaagagattaaagtcacaagggaagaactgcaaaaaactagccaagaatctccttaaggagccagaaaaccgcaacaacttttgcctctggaagcagtatgcccatctggagtggttgcttggcaacacagaggatgctagaaaagtttttgacacagcactgggcatggcaggaagccaaggactgaaggactctgaactctgtgagctcagtcttctctatgccaagctggaggtggagctggaggtggagctgtcgccggaagtgagaggggccgcctccgcccgagctgttcacatattaaccaagctgaccgagagcagcccctacgggccctacactggacaggtgttggctgttcacattttgaaagcacgaaaagcttacgagcacgcgctgcaggactatttgggtgacagctgtgtctccgatccagctcccaccgattcttgtacccgcctaattagcttgtccaaatgcttcatgctcttccagtatttgactgtcgggattggtgctgctgtacggatatacgaacaggtatttgccaaactgcacagttctgtttttccagaaggctctggcgaggggaatagtgccagctcccagagtcggagcagttttctcgaagccatcacactgatgcacgcaagcctgctgagattccacatgaaagtgagtgtttacccgctggcccctctgcgagaggcactctcacaggctttaaagctgtatccaggcaaccaggttctttggaggtcctatgtccagattcagaataagtcccacagcgccagcaagaccaggagattttttgacacaatcaccaggtctgctaaaccgttggagccttggctgtttgcaattgaagctgagaaaatgaggaaaagactagtggaaactgttcagaggttagacggtagagagatccacgccacaattcctgagaccggcttaacgcatcggatccaagccctgtttgaaaatgccatgcgcagcgacagtggcagccagtgccccttgctgtggaggatgtatttgaactttttggtttccttaggaaataaagaaagaagcaaaggtgtattctacaaagcacttcagaattgtccgtgggcaaaggtgttgtacctggatgccgtggagtacttccccgaggagatgcaggaggtcctggatctgatgaccgagaaggagctccgggtgcgcctgccactggaggagctggagctgctgctggaggattagagccgcggggaatagaccgtgcctatgaggccaagtcgcccacctggcagagccaggcggcatgagcggagaatgtgtgcgttagagacctcagcttttgaaatgttctttctcaatattaataatgtgtctgggctggcagcctctcacatctggcacacttttggggtgtgaaaatgacacaaaagctgtttacatattatatatgtgtatgtgtgtatatatgtacatagccagggagtcatgccaagtggtcattaaaccgatgatgattga

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