LOCUS       XM_066375874            3272 bp    mRNA    linear   MAM 10-JUL-2024
DEFINITION  PREDICTED: Saccopteryx leptura argonaute RISC catalytic component 3
            (AGO3), mRNA.
ACCESSION   XM_066375874
VERSION     XM_066375874.1
DBLINK      BioProject: PRJNA1130902
KEYWORDS    RefSeq.
SOURCE      Saccopteryx leptura (lesser sac-winged bat)
  ORGANISM  Saccopteryx leptura
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera;
            Emballonuridae; Emballonurinae; Saccopteryx.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_089505) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036850995.1-RS_2024_07
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 07/09/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3272
                     /organism="Saccopteryx leptura"
                     /mol_type="mRNA"
                     /isolate="mSacLep1"
                     /db_xref="taxon:249018"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="liver"
                     /dev_stage="adult"
                     /geo_loc_name="Panama: Gamboa Approx"
                     /lat_lon="9.07091 N 79.42076 W"
                     /collection_date="2019-03-18"
                     /collected_by="Alvarez van Tussenbroek"
     gene            1..3272
                     /gene="AGO3"
                     /note="argonaute RISC catalytic component 3; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 34 Proteins"
                     /db_xref="GeneID:136399949"
     CDS             328..2910
                     /gene="AGO3"
                     /codon_start=1
                     /product="protein argonaute-3"
                     /protein_id="XP_066231971.1"
                     /db_xref="GeneID:136399949"
                     /translation="

MEIGSAGPVGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVASTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQDEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    544..828
                     /gene="AGO3"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    856..1008
                     /gene="AGO3"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    1009..1371
                     /gene="AGO3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1165..1167,1210..1212,1252..1254,1264..1266,
                     1318..1320,1339..1341,1345..1347)
                     /gene="AGO3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1504..2781
                     /gene="AGO3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1915..1917,1927..1929,1963..1974,1981..1983,
                     2005..2007,2014..2016,2026..2028,2038..2040)
                     /gene="AGO3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2119..2121,2125..2127,2335..2337,2749..2751)
                     /gene="AGO3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

ccgggggcggccccgggaaggtcggcggcggcgccgcagttgtggaggggcaatgcgagcgtaagcggccgcgggcgacgcaagttccgcacccagttcacctctccccgcctcacgcttcttcctcttacctagtcgcgtgctgcctcccgccggcggctccttctgccaagagctttgggagcgcagttgctgagaagaagctgtcgccaccccgcctcgcggccaagtgagagtgcctgtcgcaccgcgtcgccccctgcgcctcctcctcgcccccggtggcgggcgtccttctcgctcgaagcactccccccagctccatgaatggaaatcggctccgcaggacccgttggggcccagcccctactcatggtgcccagaagacctggatatggcaccatgggcaaacccattaaattgctggctaactgttttcaagttgaaatcccaaagattgatgtctacctctatgaggtagatattaaaccagacaagtgtcctaggagagtgaacagggaagttgtggattcaatggttcagcattttaaagtaactatatttggggaccgtagaccagtttatgatggaaaaagaagcctttacacagccaatccacttcctgtggcatctactggggtagatttagatgttactttacctggggaaggtggaaaagatcgacctttcaaagtgtcaatcaagtttgtctctcgggtgagttggcacctactacatgaagtactgacaggacggaccttgcctgagccactggaattagacaagccaatcagcactaatcctgtccatgctgttgatgtggtgctacgacatctgccctccatgaaatatacgcctgtggggcgttcctttttctccgctccagaaggatatgaccaccctctaggagggggcagggaagtatggtttggattccatcaatctgttcggcctgccatgtggaaaatgatgcttaatattgatgtttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgacattcataatattgatgagcaaccaagacctctgactgattctcatcgggtaaaattcaccaaagagataaaaggtctgaaggttgaagtgactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacaagacggcctgccagtcaccaaacctttcctttacagttagaaaatggccaaactgtggagagaacagtagcacagtatttcagagaaaagtatactcttcagctgaagtacccacaccttccctgtctgcaagtggggcaggagcagaaacatacatatctgccgttagaagtctgtaatatcgtggcagggcaacgatgtatcaagaagctaacggacaatcagacttccactatgatcaaagcaacagcaagatctgcaccagatagacaagatgaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcaatttaaagttcgagatgaaatggcccacgtaaccggacgtgtacttccagcgcctatgctccagtatggaggacggaatcggacggtagcaacaccaagccatggagtatgggacatgcgagggaaacagttccacacgggagttgaaataaaaatgtgggctatagcttgttttgccacacagagacagtgcagagaagaaatactgaagggtttcacggaccagctgcgtaagatttccaaggatgcagggatgcccatccagggccagccttgcttctgcaaatatgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggttgcagctcattatcgtcatcctgccagggaagacgccagtgtatgcggaggtgaaacgtgtaggagatacacttttgggtatggctacacagtgtgtacaagtcaagaatgtaataaaaacatcccctcaaactctctcaaacctgtgcctaaagataaatgttaaactcggagggatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagcagatgtcactcatccaccagctggtgatggaaagaagccttctattgctgctgttgtaggtagtatggatgcccacccaagcagatactgtgctacagtaagagttcagagaccccgacaggagatcatccaggacttggcctccatggtccgagaacttctgattcaattttataagtcaactcggttcaaacctactcgtatcatcttttatcgcgatggtgtttcagagggacagtttaggcaggtattatattatgaactactagcaattcgagaagcctgcatcagtctggagaaagactatcaacctggaataacctacattgtagttcagaagagacatcacactcgattattttgtgctgataggacagaaagggttggaagaagtggcaatatcccagctggaacaacagttgatacagacattacacacccatatgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgtccttcacactatcatgttttatgggatgataactgctttaccgcagatgaacttcagctgctgacttaccagctctgccacacttacgtgcgctgtacacgatcagtttctatacctgcaccagcgtattatgctcacctggtggcattcagagccagatatcatctcgtagacaaagaacatgacagtgctgaaggaagtcatgtttcaggacagagcaatgggcgagacccacaagctcttgccaaggctgtacagattcaccaggataccttacgcacaatgtactttgcttaaaaagtctgaaaatattctctgagaggaagaactgaaagatgaaacaacgtccagcgtatgtttcgagtggagtcagttgactgaagatgcctccagccatacagaaaccaacactgtggggaccagggtctgatttttatgttgatgcaaggaagattgtttacttcatcaaggaacacagcaccattatgcaatatgaaaccagccaactgcttttttgtgcggtctcctgtaggaagtatcgccattattttgttttcactttcttgtagtctaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaaaaggtaaagaaaagataactgatggtg

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