LOCUS       XM_066084865            2871 bp    mRNA    linear   INV 28-JUN-2024
DEFINITION  PREDICTED: Magallana gigas protein argonaute-2 (LOC105329532),
            transcript variant X6, mRNA.
ACCESSION   XM_066084865
VERSION     XM_066084865.1
DBLINK      BioProject: PRJNA1118722
KEYWORDS    RefSeq.
SOURCE      Magallana gigas (Pacific oyster)
  ORGANISM  Magallana gigas
            Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
            Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae;
            Magallana.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_088857) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963853765.1-RS_2024_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/20/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2871
                     /organism="Magallana gigas"
                     /mol_type="mRNA"
                     /db_xref="taxon:29159"
                     /chromosome="5"
     gene            1..2871
                     /gene="LOC105329532"
                     /note="protein argonaute-2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     Protein"
                     /db_xref="GeneID:105329532"
     CDS             139..2871
                     /gene="LOC105329532"
                     /codon_start=1
                     /product="protein argonaute-2 isoform X6"
                     /protein_id="XP_065940937.1"
                     /db_xref="GeneID:105329532"
                     /translation="

MFPIAPGITSILHNQQLNGGQTPFSPFPAMQEGQSSIPFSTFPTEGQSSGLPFTSFPTDGQTSIPFSVFPPVQPPEGGFAFPPPQPPPGPPSGPPKPPGPPGPPKPSDFICPPRPNYGTEGKPILLRANHFQVRIPKGVLHHYDISIVPDKCPRRVNREIIETMVTAYSQKIFSGQKPVFDGRKNLYSREPLPIGREKVELEVTLPGEGKDRVFNITMKWVQQISLFGLEEALQGHTREIPQDAITAVDIIMRHLPSMTYTPVGRSFFSPPEGYDHPLGGGREVWFGFHQSVRPSHWKMMLNIDVSATAFYKAQPVIEFMCEVLDIKDVNEQKRPLTDSQRVKFTKEIRGLKVEITHCGTMRRKYRVCNVTRRPAQTQSFPLQLDSGQTVECTVARYFLERYKMKLQYPHLPCLQVGQEQKHTYLPLEVCNVVGGQRCIKKLTDMQTSTMIKATARSAPDREREINNLVRKANFNADPFLQTFGININPMMCDLQGRVLHPPKILYGGRTKAQAVPNQGVWDMRGKQFYSGTEIRVWAIACFAPQRTVREDALRNFTQQLQRISNDAGMPILGQPCFCKYATGPDQVEPMFRYLKNTYQGLQLIVVVLPGKTPVYAEVKRVGDILFGLATQCVQAKNVNKTTPQTLSNLCLKINVKLGGINNILLPSIRPSIFREPVIFLGADVTHPPAGDASKPSIAAVVGSMDAHPSRYSSTVRVQQHRQEIIQELSSMVRELLIHFYKATRFKPTRIIFYRDGVSEGQFQQVLQHELRAVREACMKLELGYQPGITFIVVQKRHHTRLFCADRKDQIGRSGNIPAGTTVDVGITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFNADELQTLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDR"

     misc_feature    502..894
                     /gene="LOC105329532"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    922..1074
                     /gene="LOC105329532"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    1075..1437
                     /gene="LOC105329532"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1231..1233,1276..1278,1318..1320,1330..1332,
                     1384..1386,1405..1407,1411..1413)
                     /gene="LOC105329532"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1570..2847
                     /gene="LOC105329532"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1981..1983,1993..1995,2029..2040,2047..2049,
                     2071..2073,2080..2082,2092..2094,2104..2106)
                     /gene="LOC105329532"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2185..2187,2191..2193,2401..2403,2815..2817)
                     /gene="LOC105329532"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gcgtcgcgtcgcgattgaagcgccctctttggctctagtcatagttgtgaacattgctcaaaattacaaagtcaaagtgaatttacgaagcctttgagggcacaatttacagataatctgtaaacatataatgccaatatgtttccgatagcgccaggtatcacaagcatactgcacaaccagcagcttaacggtggacagacccccttctcacctttccctgctatgcaggaaggtcagtcgtccattccattctcaacatttccaacagaaggtcaatcttcaggcctgccgttcacatctttcccaacagatggccagacttcgattccgttttcggtattcccacccgttcagccaccggagggaggatttgccttcccccctcctcagcccccacctggcccgccttcaggaccacccaagccaccaggacctcctggtcctcccaaaccatcggactttatatgtccgccccgtcccaactacgggacggagggcaaaccaatcctactgcgtgccaatcatttccaagtgcgtattcccaagggagttcttcaccactacgatatttcaatagtgcctgacaaatgtccacgaagagtcaacagggagattattgagacaatggtaactgcttatagccagaaaatcttctcagggcagaaaccggtgtttgatggacgcaaaaacctctacagtcgcgagcctcttcccattggtcgagaaaaggtggagctggaagttactctcccgggggagggcaaggaccgcgtctttaacataacaatgaaatgggtccagcagatcagcctgtttgggctggaggaagcactgcagggccacacccgggagattccccaggacgcaatcaccgccgtcgatattatcatgcgtcacttgccaagtatgacatacactcctgtgggacgttcattcttctccccaccggaggggtacgaccaccccctgggagggggcagggaggtgtggttcggcttccatcagagtgtgaggccctcccactggaaaatgatgctcaacattgacgtatctgccactgccttttacaaagcgcagcctgtgatagagttcatgtgtgaagtgttggatatcaaagacgtcaacgaacagaaacgccccctcaccgattctcagagggtcaaatttacaaaggaaatcagaggactcaaggtagagatcactcactgtggaaccatgagacgtaaatatcgcgtgtgtaacgtgactcgacgacccgcccagacacagtcgtttcccctgcagctggactcgggacagaccgtggagtgtaccgtggcccgctacttcctggagcgatacaaaatgaagctacaataccctcacttgccatgcttacaagtcggccaggaacagaagcacacctatcttcctctggaggtgtgtaacgtggtgggcggccagaggtgtatcaagaagctgaccgacatgcagacgtccaccatgatcaaggccacagcccgatctgccccggacagagagagagaaatcaacaaccttgtgaggaaagccaacttcaacgctgatccatttctacaaacatttggaataaacatcaacccaatgatgtgtgacctccagggcagagttcttcatcctcccaaaatcctgtatggaggaaggaccaaagcccaggcagtgccaaaccaaggtgtctgggacatgaggggcaagcagttctactcggggacggagatcagggtgtgggccatcgcttgtttcgccccccagaggacggtcagggaggacgctctcagaaacttcacccagcagctacaaaggatctcgaacgacgctgggatgcccattctaggccagccttgtttctgtaaatacgccacaggccccgatcaggtggagcccatgttccgatatctcaagaacacttaccaaggcctccagctcatcgtcgttgtactgccgggaaaaacgcccgtatatgctgaggtgaagcgtgtgggtgacattttatttggattagccacacaatgtgttcaagccaaaaacgtgaacaaaacaaccccccagaccctgtccaatctctgcctcaagatcaacgtcaagctgggcggtatcaacaacatccttctgccaagtattcgtccctccatatttagagagcccgtcatattcctgggtgccgatgtgactcatccccccgcaggagatgccagtaaaccatccatagctgcagtggtaggcagcatggacgcccaccccagccgctactcctccacggtccgagtccagcagcacagacaggaaatcatacaggagttgtcttccatggtgcgggaactcctgatccacttctacaaggcgacgcgattcaagccgacgcgcatcatcttctacagagacggcgtcagtgagggacagttccagcaggtgttacagcacgagctgcgtgctgtgagagaggcctgcatgaagcttgagcttggataccagcccggtatcacctttatcgtggtccagaagagacaccacacccgactgttctgtgccgaccgcaaggaccagataggacgaagcggaaatatcccggccggaaccaccgtggatgtcggaatcacccaccccacagagtttgatttttacctgtgtagtcatgctggtatacagggcaccagtcgcccctctcactaccacgtcctgtgggacgacaaccggttcaacgcggacgagctccagacgctgacctaccagctgtgtcacacctatgtccgctgtacccgcagtgtctccatccccgcccctgcttactatgcacatctagtcgccttccgggcccgctaccacctggtggagaaagagcacgacaggtaa

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