LOCUS       XM_064471547            6014 bp    mRNA    linear   VRT 12-APR-2024
DEFINITION  PREDICTED: Phalacrocorax carbo argonaute RISC catalytic component 3
            (AGO3), mRNA.
ACCESSION   XM_064471547
VERSION     XM_064471547.1
DBLINK      BioProject: PRJNA1098006
KEYWORDS    RefSeq.
SOURCE      Phalacrocorax carbo (great cormorant)
  ORGANISM  Phalacrocorax carbo
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Suliformes;
            Phalacrocoracidae; Phalacrocorax.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_087534) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963921805.1-RS_2024_04
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 04/09/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6014
                     /organism="Phalacrocorax carbo"
                     /mol_type="mRNA"
                     /db_xref="taxon:9209"
                     /chromosome="22"
     gene            1..6014
                     /gene="AGO3"
                     /note="argonaute RISC catalytic component 3; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 48 Proteins"
                     /db_xref="GeneID:104051415"
     CDS             226..2808
                     /gene="AGO3"
                     /codon_start=1
                     /product="protein argonaute-3"
                     /protein_id="XP_064327617.1"
                     /db_xref="GeneID:104051415"
                     /translation="

MEIGSAGPVGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    442..726
                     /gene="AGO3"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    754..906
                     /gene="AGO3"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    907..1269
                     /gene="AGO3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1063..1065,1108..1110,1150..1152,1162..1164,
                     1216..1218,1237..1239,1243..1245)
                     /gene="AGO3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1402..2679
                     /gene="AGO3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1813..1815,1825..1827,1861..1872,1879..1881,
                     1903..1905,1912..1914,1924..1926,1936..1938)
                     /gene="AGO3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2017..2019,2023..2025,2233..2235,2647..2649)
                     /gene="AGO3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gaaatcggtccctctggtagccgccgcgcgccgccaccgcctgaggggacgggacggacggacagaggggagcggcgggcggccgaggcgacgcggcgggccgcagcctgcagggagtggggcgggccgccgcccagcgcagccccgaggggagccccgagccggccgccgggcccggctccgcgcggagcccgcagcccccagcggctgcgcccagctccatgaatggaaatcggcagcgcaggacccgtcggggcacagcccctactcatggtgcccaggcgtcccggctatggcaccatgggcaaacccattaaactgctggccaactgcttccaagttgaaatcccaaagattgatgtctacctctatgaggtggatatcaaaccagataagtgtcctcggagggtgaacagggaggtggtggactcaatggtgcagcattttaaagtgacaatatttggggaccgtagaccagtttatgatgggaaaagaagcctctatacagccaatccgcttcctgtggccactactggggtggatttggatgtgacattaccaggagaaggtggaaaagatcgtcccttcaaagtgtcaataaagtttgtttctcgggtgagctggcacttgctgcatgaagttttgacaggaagaaccttgcctgagcctctggaactagacaaacctatcagcactaaccctgttcatgctgtcgatgtggtgctacgacacctaccctccatgaagtatacccctgtgggccgctccttcttctcagctccagaaggctatgatcaccccttgggtggaggtagggaggtctggtttggattccatcagtctgttcggcctgccatgtggaagatgatgctcaatattgatgtttctgccactgccttctacaaagcacaacctgtaattcagtttatgtgtgaagttcttgacattcataatattgacgaacaaccaagacctctgactgattctcatcgggtaaaattcaccaaagagataaagggtctgaaggtagaagtgactcactgtggaacgatgaggaggaaataccgtgtttgtaatgtaacaaggaggcctgcaagtcatcaaacctttcctttgcagttagaaaatggccagactgtggagagaacagtagcacagtatttcagagagaaatacaacctccagctgaaataccctcatcttccttgcctacaagtgggacaagaacagaaacacacctacctgcctttagaagtatgtaacattgtcgctggccagcggtgtatcaagaagctaacggacaatcagacatcgactatgataaaggccacggcgagatctgctccagataggcaagaggaaataagcagattggtgagaagtgcaaattatgatgcggatccatttgttcaagagttccaattcaaggtccgggatgagatggcccacgtgacggggcgcgtgctcccagcgccgatgttgcagtatggaggacggaatcgaacagtggcaaccccaagccatggagtatgggacatgagagggaagcagtttcacactggtgttgagatcaaaatgtgggctatagcttgctttgcaacacagagacaatgcagagaagaaatactgaagggttttacagaccagctgcgcaagatctccaaagacgcagggatgccgatccaaggccagccctgtttctgtaaatacgcccagggtgcagacagcgtggagcccatgttccgacacctcaagaacacctattcggggcttcagctcatcattgtcatcctgccagggaaaacaccggtgtacgcggaggtgaagcgtgtgggagatacactgctgggaatggccacacagtgtgttcaagtcaagaacgtcattaaaacatctccgcagaccctatcaaatctgtgcctgaagattaacgttaaactaggaggaatcaacaacatccttgtacctcatcaacgaccttctgtgttccagcagccagtgatctttttgggagccgatgtcacccaccctcctgctggagatggaaagaagccttccatagctgctgttgtaggtagtatggatgctcatccaagccggtactgtgccacggtgagagttcagcgaccccggcaggaaatcatccaagatctagcctccatggtgagagagcttctcatccagttctacaagtcaacacggttcaagcccacgcgtatcatcttctatagggacggggtttctgaaggacaatttcgacaggttttgtattatgaactgctagccattagagaagcctgcatcagcttggagaaagattaccagcctggaataacctatatagtggtgcagaagcgacatcatacacgattgttctgtgctgacagaacagaaagggttggacgaagtggcaatattccagctggaacaactgtagataccgacattacacatccatatgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgtccctcacactatcatgttttgtgggatgataactgttttactgcagatgaactccagctgctgacttaccagctctgccacacatacgtgcgctgtacacgatcggtttctatacctgcaccagcgtattatgcgcacctggtagcattcagagcacgataccatcttgtggacaaagaacatgacagtgctgaaggaagccatgtttcaggacaaagcaatgggagagatccgcaggcactcgcgaaggctgtacaaattcaccaagacaccttacgcacgatgtacttcgcttaagtcaataaaatgggagcatactcactgaaaggaagaactgaaaaattaagccacatacagtgtatgtttccagtggggttggtttatggggtgtgcctccaatcatgctgaagttgacactgtgcaggggcgagaggctaacccttaaattgacacaaggaagattgtttacttcatcgagggactcagcactattatgcaatatgaaaccagccaactgcttttttggcgcggtctcctgtaggaagcaccgccatcattttttttttaatttctcgtagtttaaccctcttatgcctttacctcaagttgctcggcagcacaactatctttgcaaaaaaaaaaattttaaaaaatcgatggtgtaatttaaaaaaagcaaaccacctttatagaaacaatcacagtgattgtctgggggagggaagtgtgcaaaaaaaaaaaaatttaagtttttttaccccatttcattgaggaatcttcctcaatattgccatccagcattcgaaggtgagcatatccgagtacatttgaatgtacagcactagctaggaaaaattaagggggaagatgttttgcacactaatccaataatttgaaagtaatttagccaactgctgcctttgtgtcttttcttcacagctttggagttctcggctccaatagttccctttcaaaaagcaaagaagctagtggtattacgtgcaggcagtagcgatccgaactcttcttgctccctggtgaatttactaaagctgctcttttacctagtccaaaagtttcaattattttctatctggcaaatcaaatatgttgaagcttcacgtaagatcagatgtcccaagttttatggaattacatacagtaaacaccagaactgaaactttagagctaaggtgttcttggaaaaaagaaaaatgctagtttacttgctgcctctcacaccttaatgtgatttcatatgtatgtgtttttgaagtttagcttccttttgtttcttttatatttattagagtaataataatgctttaatttaattattacagaacatatggtcaacatcaacttttattttttagaaatgtaaccatgtttatttttagaaaactgacaacttgttttgctatcttttagtgcaataagcgttctaaaggaaaactgtgtccattgagctgtactaaagcagtgttgtaccactaactgtggaagaatggacacctccatgattttaaatggacaaagcaaaagccttaattttgaaaggaaagttttatagtcagaaggaatcttgacttttccttttttaaatcaaaaaatagcaaaaatgctcctagaattctgcaagcttcacttgtcatcgcagcatttgatttaacaaaggaattggccgtatttttggctttgaaatgtggaggatatttgaattaaatggaaagggttttttattaagatctaagtttttacatgcttagttaaatctatttgacatcagtaaaatgtctggaattaataaaagtttttaggcttttttcctctttgataatgactttccttttaaaattaagttattggtaacttcatttcactttgcaaataaagagggctgggatagttctaacatgttaaatcgctgaaatgtgaaacaaattaacgggactctttcattccactttagaggtaaaacaatatttaagatgtcagacgagcatttattcaacaaggggactggggagttttgcactttgtaaactcgtgaactgcatttttgactgtttttatttgcactggttcatagtatatatactgcagatcgtttgtatgggcattgctgttatcccagcccttctgaactccacctgctctccacatgaaaaccagtgggttggtataagtagcttatctcctgtcattctcatgaaatccgctgtttgccaatatactgtattttgagcctaaaatctgagcccgttttgcttcaacaggcatgaatctcccccattttttctgccagaaaacaaagtactgtattttgtgcatttgtatattgtattgaaatgtatgtagtgctgttcacaacactgtttcaaagacctttactaagcagttagtgtatatacatattttatctcccaatatcaaggaagataatgtaaaaagactaactttgcaaagctaaaattgcactggagctagtcgtgacggtgggcggttggctagtggcttgggggtccccggagaggaggtggggggggcgatcacgggagacccggcagaccccgacgtgtcggagagtctctgggctcctgggagccgcacgccttcgccagctgcacccgcaggcccgggaccggcccagccacgctctttgacttcttaatgcacttacctttcagcgccttcgcgtaaacctgccgcagggaggtcggtgtaaccgaacaagtcgagtgagatggtttccgaataagtctctcaaacgtttttcttggtctgtgacctggcggttctctctcagaagcgctctagctagtagttctgtttataaaaggttcaggttaggctttttacagaaaaattgttttaaaatagagaattttttttaaaacaaaatttacaaagaattcttgtggatttctggcgtttaggtgaaaattcctttttaaaacgtcttttaatgctccttttaaagacactgtgcgcttctcatcctgcccacgctcagtgactatgatttcagaagcttttttgcttgctactttcaccaaaagataaagtaaagaaaatgcattgggaaagtgacttaagttccttgtcgagcgagcattttacctggttttcatgtgaagagtatttggaagttttaatctctattcttggttttgcaaatatctacgtaaagtgccgatacttatttgtattacgatatcaagttactggcgttgtgagggccacacatttatgatgctgtagctgctatatttatttaaatggagatggacaattactgcactaaggaatgaggagataagcaaggaatcaaggttagttagatatcttgggtgttttttttttttcaacagagaattaatggtgtgaaatatcaagtgtaacaaagggtgctgtcattttaactgagattaaatagccagatattcttcctttgtttaaaaacatatatattttgatgtttgcagtttgggggtgggggt

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