LOCUS       XM_055254947           12428 bp    mRNA    linear   PRI 17-JUL-2024
DEFINITION  PREDICTED: Symphalangus syndactylus argonaute RISC component 1
            (AGO1), transcript variant X5, mRNA.
ACCESSION   XM_055254947
VERSION     XM_055254947.2
DBLINK      BioProject: PRJNA946760
KEYWORDS    RefSeq.
SOURCE      Symphalangus syndactylus (siamang)
  ORGANISM  Symphalangus syndactylus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hylobatidae; Symphalangus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_072441) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Mar 6, 2024 this sequence version replaced XM_055254947.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_028878055.3-RS_2024_07
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 07/16/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12428
                     /organism="Symphalangus syndactylus"
                     /mol_type="mRNA"
                     /isolate="Jambi"
                     /db_xref="taxon:9590"
                     /chromosome="12"
                     /sex="male"
                     /cell_line="Jambi"
                     /cell_type="lymphoblastoid"
                     /tissue_type="blood"
     gene            1..12428
                     /gene="AGO1"
                     /note="argonaute RISC component 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 133
                     long SRA reads, 1 Protein"
                     /db_xref="GeneID:129468933"
     CDS             228..2441
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X5"
                     /protein_id="XP_055110922.1"
                     /db_xref="GeneID:129468933"
                     /translation="

MLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQPSPLPSLGPLTFLSSQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    330..482
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    483..845
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(639..641,684..686,726..728,738..740,792..794,
                     813..815,819..821)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    978..2312
                     /gene="AGO1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1398..1400,1410..1412,1446..1457,1464..1466,
                     1488..1490,1497..1499,1509..1511,1521..1523)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1602..1604,1608..1610,1818..1820,2280..2282)
                     /gene="AGO1"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      12428
                     /gene="AGO1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

cctcgccggcctggcattggcactgtggggaaaccaatcaagctcctggccaattactttgaggtggacatccctaagatcgacgtgtaccactacgaggtggacatcaagccagataagtgtccccgtagagtcaaccggtcgactttgaggtgacaatccctggggaagggaaggatcgaatctttaaggtctccatcaagtggctagccattgtgagctggcgaatgctgcatgaggccctggtcagcggccagatccctgttcccttggagtctgtgcaagccctggatgtggccatgaggcacctggcatccatgaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttctataaggcacagccagtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcagcccaagcccctcacggactctcagcgcgttcgcttcaccaaggagatcaagggcctgaaggtggaagtcacccactgtggacagatgaagaggaagtaccgcgtgtgtaatgttacccgtcgccctgctagccatcagacattccccttacagctggagagtggacagactgtggagtgcacagtggcacagtatttcaagcagaaatataaccttcagctcaagtatccccatctgccctgcctacaagttggccaggaacaaaagcatacctaccttcccctagaggtctgtaacattgtggctgggcagcgctgtattaaaaagctgaccgacaaccagacttcgaccatgataaaggccacagctagatccgctccagacagacaggaggagatcagtcgcctgatgaagaatgccagctacaacttagatccctacatccaggaatttgggatcaaagtgaaggatgacatgacggaggtgacagggcgagtgctgccggcgcccatcttgcagtacggcggccgggtgagcaggaaccgggccattgccacacccaatcagggtgtctgggacatgcgggggaaacagttctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaaacagtgtcgagaagaggtgctcaagaacttcacagaccagctgcggaagatttccaaggatgcggggatgcctatccagggtcaaccttgtttctgcaaatatgcacagggggcagacagcgtggagcctatgttccggcatctcaagaacacctactcagggctgcagctcattattgtcatcctgccagggaagacgccggtgtatgctgaggtgaaacgtgttggagatacgctcttgggaatggctacgcagtgtgtgcaggtgaagaacgtggtcaagacctcacctcagactctgtccaacctctgcctcaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgccgtttttcaacagccagtgatattcctgggagcagatgttacacaccccccagcaggggatgggaaaaaaccttctatcacagcagtggtaggcagtatggatgcccaccccagccgatactgtgctactgtgcgggtacagcgaccacggcaagagatcattgaagacttgtcctacatggtgcgtgagctcctcatccagttctacaagtccacccgtttcaagcctacccgcatcatcttctaccgagatggggtgcctgaaggtcagctaccccagatactccactatgagctactggccattcgtgatgcctgcatcaaactggaaaaggactaccagccggggatcacttatattgtggtgcagaaacgccatcacacccgccttttctgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggaccacagtggacaccaacatcacccacccatttgagtttgacttctatctgtgcagccacgcaggcatccagccatctcctctgcccagcctgggacccctcaccttcctatcttcccagggcactagccgaccatcccattactatgttctttgggatgacaaccgtttcacagcggatgagctccagatcctgacgtaccagctgtgccacacttacgtacgatgcacacgctctgtctctatcccagcacctgcctactatgcccgcctggtggctttccgggcacgataccacctggtggacaaggagcatgacagtggagaggggagccacatatcggggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaggagctgtgccacccaaatccagaggaagcaaggaggagggaggtggggtagggaggagtgtaggacgccttgtttccttctgtagaggtggtgtaagagtggggaacagggccagcaagacagaccaccagccagaaatctctgatatcaacctcatgtcccccacccctcaccccatcttgtcacatctggccctgaccccactggaccaaaaggggcagcactggtgcccaccatacacacaggtgtctcatgtgactcacagtgctaaagactcatgcttgacagcttggtaaggtcaactctgtagccctgcagacaaaagctggttaggtttgggtttgatactttagatgggaaagtgaggggcttgagaaagtgggtgggaggagggaaggattttttaggagccttaatcagaaaaggactagatttgtttaagaagaaaaatgaaaccagacccagatcaatattttaggatactagatgttttaatgggttcagaatccagtttgtaggaagattttttaatggttttggttgctcctcccccagctgccaccccccaccttccccttattcctctctgtccacattttctgccccaccttacttctcctccctgacagacatccagcccctagtaatacttaaggcactatggcacttagctttgaagtgacacgaccctgtcttccttccgcccgctggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctttctttggggaatggggtgggggtgggagaggaggtagatggggaagaaataccccagacccaacaaacctccagccagaaagccagctattttgcatttgaaggaattgacttcctcattcattgagctttttaaaagatcacaacctcaagatggttataatccattgacatttgcactttcaaacatgacaagtctcggagctgctgagatgactggcccctggcctttccacttacgcctccttttctccttgttcctcctacctcccgccccacccaggtctggagttactttcatagcatttttcactcttggcttattttctcccttgatggtcaagtctcttatgtttcaatatttctaaactggggtgtcttataacaaaaaactcttaggtctaaaatgagaaaaaagagagaaaacaaaatgttatttttataccataacttgagtgtattgccaaaatttggaaatccttcccatgcctgatgagtttatatcccggaaacattgagccatcagaatgaactgtgtacctgacctggctaggtagggagggggtggttatcgccccaagatggggtccaggctccatccttcctctgtgcagataataccttttgcttgctatagcctccctcctctgcactgtcctgcactctttcttgcaagtgcatctttttccttcccctggactgtcctctgaccctttggctcatcctagattccagtgtgtcctgtggacaggctggggaattttgctgctccctattgcttctgtttacacaaatgaatttttcctggtttcccactagggcatgtgagtgggtggcatgggcttgtttttttttttttttttttttttgtcatcttgagacatggggtttggctgtcttgcaggactggagaaggtggtggttctagcttggtctctgctggccttgaagcaagcatcccccactgccctttttccttgactgttcatttttttcctgccccactgcttgggatggggagttgcaacttcagtgtggaatttcctctttttgaggaggctgggcttggatctatcctgatctggtgatgaagccatgattactttagacctagcccaggcttggaggccagctggaggaagaagggtctaaatcctggcctgtagagttagaactaccatttcctcccgtcagctgcccttgtatgacccagatttgctatgcaaaacaatctatcccaggttctgttctggttggctacattgttcagcaactcataaaacgtagcacaaacattcattgtggagaaagcatcaggactgttgagtaactcctcctttacttttttcctgctggctacagcatggggtgccctatataggcacaagcccagctgaagaacagaatggagggctctgggaggaggcagctcactggagagcctacattccttacacaagtgcctaaagagagtgatgctaacactccatctgccctgtccattgccttcatatacagtctacttcgtgttctgtcaccctttggggaggggagctctcctgggacagtgggctctgcatgttctctacttgggtacattttggggctaggatcagggcactattcctggagggtccagtcattcaccagcatttgcaaatgtccatagggagcaggtggcagcctctactcccagcaacaagtttgtgttctctccttttctctctttgcctcactctctccagttggttttcagctggggcttgaaatgcatttttagccctttggcatggcatatgccattcaagaaataaaaaacaagagaatcagctttgggcaatgacaagaaatgacttcttactctgatttttttgtaaaaaaataatttttgagacttgaaaaataccccgaccttgaggattattcctgtttgaaaggtggtgcatgcagatggagaagtggtgttggcagcaagctttggctcgtgtggatttggtttaagtggtgcttcttacccaagcttcaaggaagtgcttgggggacccccagcctcatcctcttagttgggtctcttgctccctttgtaccactgttttgccttccttttcctcttctctctttccctggcttcctttcccttttcttctattcactctgcttgcttgctggccggcctgcctgcctgcctgcctgtctgcctgtctgcctatgtgatgacaaaatctctgcatgactgcaatgattccactgttagctggcagggtcaggcttagctccttgactgcagaagaccaagaacctgttccccaagcccagagatgtccacctgggctggactgccctcaagcttatactagagaagagcaactgacctgcctaacttgtgtgaagccaggagggtttctggcattttccacacctgtccactccttggagctggtttctctcattgctttttctaaatctggttctttctctctttacctgggcctggcttttctgagatcgtcttagggttgagctacttgggtatcctgggtttgagtgtcaggggatggacataaaggaaaaagagtgatgagaagagaatggagagaatttgaataaaaggtgggaaaggagagcactgttctttgattgtttatccagtccaacctgatccattagggattgaggtgctacactggcctccagggataagcctggggctattgttgctgggaacttaggcttaacataaagccgaagaagaagatacctagaaatttgaaacttccctaaaaagctcctaatgcccacctgctagatagcttctccgtggcctcctatttagctaagcagcagtgttttgggatacttttttttttctgtttgtgaataaggccagcactcaagatgggcagccaagggcgcactgactattagctggcccataggatatctgtaaggctggtgggacaattttggacctggaatcatgtgtaactaacaaggttggaagtttcttccccatcggggtagaaaaatcatctcaaactagccaaaaggcagttttggaaactacattggaggaagttatttttatttatatatggggcctaggccaatccaggatggtagctggaataccttccttcttaaaatctgatcatggcagggatatgcagggcactttttactatttggccttctaagcagattgggaaggaggtattttctgttcttctctttcctccgacttaataggacttgccttctccctgggcagggagagaggctgggttggtgctctccccttactgtattcatactgacttagaacctctggctgctgtttgggcgtccaagaaagggaggggaaggaatgagctagaaacaaaacagaatgaggtgggaaagggagatttccttctttacagaggaaaataggaaaccctccaagaattgtgcaagtaaagacatttgttgaatgcactgagtcccttggtgtagtagcaataaggaaaaatgaaattactttcctgtgcacacagtccagcctaattggtatgtgatgttgcacttagcagccatgtggtgggcatgtgtgactactctggttttcactttagtttctaaactttttatccctctcaagtccagcatggatggggaaatgtctctggatccccatagctgtgtacttgtttgcatttgtttccctttgagacttgtgtttgtgtcctgctttgagctgtaccttgtccagtccattgtgaaattatcccagcagctgtaatgtacagttccttctgaagcaagcaacatcagcagcagcagcagcagcacaattctgtgttttataaagacaacagtggcttctatttctaaagtgcggtctttctctttttttacctaccagcaaaacaaacttttgggactgattacatctctaatagattttaggtgagaataatactgtagactgttatgcaggaatacttcacagagccttcatttattcttcaacaaacatgcaaagcactgtgccagcagtactgtggggagggcaggcacaattcaaaatgaggaaaatagtgtctgtctcgttaagggaattaagtttggtgggggatatgattagccaaatagtcccctggcataggaggaagatagtgagggagtggaataaggctacagcaacgaatatagggaggaagggacagatttgagagacaagatagaattaataggactcgatggctggtgggaggagaagacaggagtagaggttagctcccaggtttctccttgacaataggagtgtgttgggacattctgccagtcaagatgggggtgacggggagactgtagaaggaaggtggggagtttttgaagaaagacaatgtcgtatagactgagttttgaggtttttgtggggcaggaagggtaaggtgtccggtaaacacaggttggtgctcaggtaagactgtaaaactgcatttatagatatgggagtcttatagatggtagttaaagccataggcatgaatgagatagcttagaaaaagagaagagaaacatagtatacagccccctaagaaactcaatttaaaggttcgggggaggaagcagatcttaaggtgacagatcactggtagacagtttgtgggttttttgtttctttgtttaaccagtttagtgaggtaggagaagaaatcagagtagaagaaggttcatgaagggagtgattaacaacatgaactgctgcagagagggagttcttttttttctgtttgttttacctttctactccccatcttttggggatcttataactctatgactcacttaggttattctccagtatttcttgaaaatgagcattggaaaagccaactctaaagtggctaaaactaggactttcgagttcaccacaactaccaccaattaggagataattgtaaaagaataaacaaaacctaattttgttcctagccaatattataaactgtgttccagtgtactagataatagtagcatactatatttatttccataacttgtcttctttagcacctgtgaactcctaggagcagaagctacattctcttcatttttgtcatctcagggtcatggcatataccaacggatcagtatgtgcaaatataattaataggctagtagtctgtggtttatgagtatgggctgggtgggcagcagatcaagaagtgataggcatacacaggatgaactcagaattcctgaatcttcaggtaagcagatacttaaccagattatcattgtattttcccactcaccccaagttggaggttctatggttttgtactttaagctggtggtataattgtcaagcatgtaaattctggcattctttctggtactgctagagcattgttatttctatgcatgggggtaagaaggctcagagaaggattctggcagatagcccagtgagaaatcgtcagtggcagccagtatgtacatacgtggacctagcattcctctggaggccaagtgttgtgaattggcctgtagctatcacctggcagactcccttggcaaagagccagccagccccatgcctcttttcagcagcaagggttagggaggttggttgaacttgaagagcagattggacatggagcagattttgcccacttgaaataagacataaatttatgatcccgagtgaggcagaaataaagtacttagcagggggaataggaggaggatgattatggcaaattttgctataaactttagttttagaaaagattgatattgaaaagccttcaggatttgcctgtggttgctactcaagttaaaaagactgggagcctgcattgtctggtcctggagttcaaggttttcagtgaaggcttgtcctggcacccctgggcattccttttcattactggttgagcacccttccttctgctctgtcatttggcaaaatatgctggagcacattctggactagcagttgccttggggtagtcaggctgggtatttgtttggtacctcttggtgtagcagaccccagaatctcatggcaattaggatttggtggctaaacgaaagagtgcaaggaaaagactagttggaagttctgagtctgggccatccttaagctgctgtctactgcttgaatgggaagtaatgtcgaattggaaaattaactcaccttttttgtttctagctttgcagacatttattcctctgatgataggctgagaaatgcctaggcaggcttagaaggcacacagaacatgacagaagtactccttcaaagcagctgtgtcaagaaggaagagctggaaaagtggatttgctggggaattagatgcatttagttttccacttatgcacacctgccttctccagtatatcataccaaggttttttaggcctttgtggcttaccctgcaggaacatactgtcctgttgttctggactttagcaccttcaccaccatcctcttggcaatggttttttgtttgggctttttttttttttggacaaagtgtaataatattgagggacctttctagggagccgttggtccttcgtccccattttccaaagggagggaactttcctcttaaaagagacagtaggaacttttagccaggtttctggaaaaggcctgtgggctattaatgagagtgagctgcacgaggaggaagggtttgtttgggtactttgaagtacttggctaggtattttctacagtatcttatataattgcatcttacagcatctttacatgcgaaatagtttatcagttatcttcaattgcatattacaaaattctgattaaatttttcttaaataagaaaactatcatttcatatggcaagaaatcctaatttaatgttactccaaggttggttaattcagtggctcagtgataacagcaaagactcagtttcttgaaatctttttgctctgccatcctccatgtttatcctcatgccagttcgcctcatggtcccaatatggctactgtaattctgggaaggaaatgctgacagaaccgtgtctggcaaaagagagacaaatttttctgtgtccttctaaagcaaggaagtctttccctggaagctccagcagatacggcctcatggctttgctagaaatgggtcatctcactcctgtcattggcaaagcaagtaagatcatccatcaggagtggcttaatgaattatcctttgagtcacgtagactagaaagttcagtcatgtctactagcaagaaagaagataagagctattggataagcagcatctagtctcaaaggtacttcaacttttacagatgagaaacatgaatctgagtgactttcccaggctcacagcaagtaagagagggccttcagtgttagctgtgtctgtccctaaagcccatgttttatattgtatcttgctagagtataaagtaacttactttctaccttgtagaaactgatggtctaggagaagagatttgaactcaggtgcccagttgactctaatcttggcccatgtgagaggattgtactcagttgctctcctcatccagtgatgtttcttgtctaacacaagaagcctaggagtagaaagtcctaagtggagtagaataatagcggcagcagggagggaagtgtgcactgtgtgtccctgagcctgacttactgggcagggacgtggcacttaaaagtggcagctagccaccctgtctttcctgcatgcactgagtatttggtagctcattatgcctttccttagcgaccagtgatattgatcatcttttcatgtgcttacgtactatccccatatctttgttgttggcatcttttacccattgtatttgttgtttttgagacagtgtctcactctgtcacccaggctggagtgcagtggcatgatcacggctcactgcagtttctgcctcctgggctcaagcaatcctcccacctcagcctcctaagtagctgggcttacaggcacacaccaccacgcccagctaattaaaaaaaaaaaaaattttttttttgtagcgttcggtctcattattattgcccaggctggcctctcttagcttcaagctatcctcccgcctcggcctcccaaagtgctggaattacaggcataagccactgggcccagcctcttttacctgcttcaaaattgagttttattgagttgtaagagttctttattcattttgaacacaagtcctttgttggatatatcttttacatctatttttcccagtctgtggcttgccttttcattttgaagagcaaaagtttaaaattttgcgaatttattaaagctccatttgttgcttttttcttttctagtttatacttttgtatcatattttaggaaattttgcactgggtatttgatggctcctgaggagattcaactttcagagggcactgatttctctgcacctgagattttgtactatttctgtatttctttcttctcagaacaaccagtgtcaccaggtatgagagcagagttttagtttgtttgctcagttccattcttgaagcttatttatttattcatctatctatccatcaatccaacaaatatactgaatgctgctatgtgccaggcactggcactgttctaggtactggggcaatgatagttaagataatacccaatgaccctgttctgtaagagcagactcagttgggaatgagttatccaaatatagggtgtacatgtagtcaggagagagcctcatacagctttgcctttggcagaatccttcaaacctctttgtcttcctacttcttgatattacaaattatgagcctttcacatgcgttcactctaaagaggtgggttcctggatagcagaagtagataggaaggcatcattgacatttactgagatggattgaatcagagggtgtaaattctgctccatcaatgtcgaaaaggactagcccaccccaagggtttatcactgtcaccatgtctaatgtctactctggaagaagctgaagaagtctgcctttgtttagggaaccagttccagaatcagaggggttgaggatataaaagacccttgcacaagagttggtatttaccctgtcagatgctgctaccaagatttggattgtgtacagtcgaggattaaaaatgacttttaagatgca

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