LOCUS       XM_018563609            2797 bp    mRNA    linear   VRT 30-SEP-2016
DEFINITION  PREDICTED: Nanorana parkeri argonaute 2, RISC catalytic component
            (AGO2), mRNA.
ACCESSION   XM_018563609
VERSION     XM_018563609.1
DBLINK      BioProject: PRJNA344660
KEYWORDS    RefSeq.
SOURCE      Nanorana parkeri
  ORGANISM  Nanorana parkeri
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Dicroglossidae;
            Dicroglossinae; Nanorana.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_017306948.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Nanorana parkeri Annotation Release
                                           100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2797
                     /organism="Nanorana parkeri"
                     /mol_type="mRNA"
                     /isolate="BGI_ZX_2015"
                     /isolation_source="muscle sample"
                     /db_xref="taxon:125878"
                     /chromosome="Unknown"
                     /sex="female"
                     /geo_loc_name="China"
                     /collection_date="Aug-2012"
     gene            1..2797
                     /gene="AGO2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 35 Proteins, and 96% coverage of
                     the annotated genomic feature by RNAseq alignments"
                     /db_xref="GeneID:108792766"
     CDS             75..2651
                     /gene="AGO2"
                     /codon_start=1
                     /product="protein argonaute-2"
                     /protein_id="XP_018419111.1"
                     /db_xref="GeneID:108792766"
                     /translation="

MYSGAGPVLAPPPPPPLPEYTFKPPSRPDFGTSGRTIKLQANFFEMEIPKIEIYHYEIDIKPEKCPRRVNREIVEHMVLHFKAQIFGDRKPVFDGRKNLYTAMPLPIARDKVELEVTLPGEGKDRIFKVAIKWMACVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCANPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPFVREFGIMVKDDMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELHLKTFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLIVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFTSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQVHQDTLRTMYFA"

     misc_feature    312..569
                     /gene="AGO2"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    597..749
                     /gene="AGO2"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    750..1112
                     /gene="AGO2"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(906..908,951..953,993..995,1005..1007,1059..1061,
                     1080..1082,1086..1088)
                     /gene="AGO2"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1245..2522
                     /gene="AGO2"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1656..1658,1668..1670,1704..1715,1722..1724,
                     1746..1748,1755..1757,1767..1769,1779..1781)
                     /gene="AGO2"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1860..1862,1866..1868,2076..2078,2490..2492)
                     /gene="AGO2"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

ccattgtcgccctcgcgggatagcgagtctgcgtgtgtccttcggcttagctcgtgaccgcccaaaccagcaccatgtactccggagccggccctgtgcttgcaccgccgccgccgccccccctgccggagtatactttcaagcctccatctagacctgattttggcacctcagggaggaccatcaagctgcaggcgaacttctttgagatggaaattcccaaaatagagatttatcattatgaaatagatatcaagccagaaaaatgtcccaggagggtaaacagggaaatagttgaacacatggtcctgcatttcaaggctcagatctttggagatcgtaaaccagtatttgatggcagaaagaacctctacactgcaatgcctcttccaattgccagagacaaagtggagttggaagtgacactgcccggggaaggaaaggatcgcatcttcaaagttgccattaagtggatggcttgcgtcagcttgcaggctctacacgatgcattgtctggacggcttcccagcgtcccttttgagactatacaggcgttagatgttgtgatgagacatttaccctctatgaggtatactcctgtaggtcgttctttttttactgcatccgaaggatgtgctaatcctcttggtggaggtagagaagtttggtttggcttccaccaatctgtcagaccttcactctggaaaatgatgctcaacatagatgtatctgctacagcgttttataaagcacaaccggtcatcgagttcatgtgtgaagttttggattttaaaagcatagaagagcaacaaaaacctctcacagattcccaaagggttaagtttaccaaagaaattaaaggcttaaaagtagaaattacacactgtggacaaatgaagagaaaatacagagtgtgcaatgtaacaaggcgaccagcaagtcatcaaacattccctctccagcaagagagcgggcaaacggtggaatgtaccgttgcacagtacttcaaggatagacacaaactagtacttcgctaccctcatcttccatgtttacaggtcgggcaggagcagaaacacacatacctccctctcgaggtatgcaatatagtggcaggacaaaggtgcataaagaaactgacagacaatcaaacctccactatgataagagccactgcccgctcagctccagaccgccaagaagagatcagtaaattgatgcgcagtgcaagttttaatactgatccgtttgtacgggaatttggtattatggtaaaagatgacatgacagatgtaaccggaagagtcctacaacctccttcaatcctatacggaggcaggaataaggccattgccacccctgtccagggtgtgtgggatatgaggaataaacagttccacactggcattgaaattaaagtgtgggcgatagcttgctttgctcctcagcggcaatgtacggaacttcacctcaaaactttcactgaacagttgcggaagatctctcgcgatgcaggaatgcccattcaggggcagccatgtttttgcaaatatgctcaaggagcagacagtgtggagcccatgttcaggcatctgaagaacacctatactggcctacagctgattgttgtaattctccccggaaagacccctgtgtatgcggaggtaaaacgtgtgggagacactgtgctgggcatggcgacgcagtgtgtgcagatgaaaaatgtacagagaactacaccgcagactctgtctaacctctgcctgaagattaatgtcaagttaggaggcgtcaataacattttgttaccccagggcaggcccccggtcttccagcagccggttatattcctcggagcggatgttactcatcctcctgcaggggatggaaaaaagccatcgattgcagcagttgtaggtagcatggacgcacaccccaaccgctattgtgccactgtaagggtgcagcagcacagacaggagatcatccaagatttggctgccatggtccgagaactgcttatccagttttacaagtcaacacgtttcaagcccacacggatcatcttctacagggatggggtttctgaaggacagttccagcaggtgttacatcatgagctattggcaattagggaagcctgtatcaagttggaaaaggattatcagcccggcattacctttatcgttgtacagaaaagacatcacacgcgacttttctgcacggacagaaatgagcgggtggggaaaagtggaaatattccagctggtacgacagtggacacaaaaatcacccacccgtcggagtttgatttttacctgtgcagccatgctggtattcagggaacaagcaggccctcacattatcatgtcctttgggatgacaaccggtttacttctgatgagctgcaaatcctcacttaccagctctgtcacacttatgtccgctgcactcgatctgtgtctatccctgccccagcctactacgcacacttagtcgcatttagagcccggtatcaccttgtggataaagagcatgacagcgctgaaggcagccacacttctggtcagagcaacgggagagatcaacaagcacttgctaaggcagttcaggttcaccaggacacactgcgtacaatgtactttgcttaactggtgctggtacccagatcttataggcactaaccaaggaggattcacgccagaccagctgcacttacttgtattgtagtccgcactacagtgacatccaagtgcaatctaccacaaccctatctttatcattatcccttgatcac

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