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2024-11-19 20:36:01, GGRNA.v2 : RefSeq release 226 (Sep, 2024)

LOCUS       NM_020384               2961 bp    mRNA    linear   PRI 04-AUG-2024
DEFINITION  Homo sapiens claudin 2 (CLDN2), transcript variant 1, mRNA.
ACCESSION   NM_020384
VERSION     NM_020384.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2961)
  AUTHORS   Eguchi,H., Yu,Y., Yoshino,Y., Hara,H., Tanaka,H. and Ikari,A.
  TITLE     Plasma-activated medium ameliorates the chemoresistance of human
            lung adenocarcinoma cells mediated via downregulation of claudin-2
            expression
  JOURNAL   Arch Biochem Biophys 751, 109846 (2024)
   PUBMED   38056686
  REMARK    GeneRIF: Plasma-activated medium ameliorates the chemoresistance of
            human lung adenocarcinoma cells mediated via downregulation of
            claudin-2 expression.
REFERENCE   2  (bases 1 to 2961)
  AUTHORS   Telgenhoff,D.
  TITLE     Claudin-2 in hyperproliferative migrating keratinocytes and
            migration inhibition via siRNA knockdown
  JOURNAL   Anat Histol Embryol 52 (5), 723-731 (2023)
   PUBMED   37147871
  REMARK    GeneRIF: Claudin-2 in hyperproliferative migrating keratinocytes
            and migration inhibition via siRNA knockdown.
REFERENCE   3  (bases 1 to 2961)
  AUTHORS   Arai,W., Konno,T., Kohno,T., Kodera,Y., Tsujiwaki,M., Shindo,Y.,
            Chiba,H., Miyajima,M., Sakuma,Y., Watanabe,A. and Kojima,T.
  TITLE     Downregulation of angulin-1/LSR induces malignancy via upregulation
            of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism
            in human lung adenocarcinoma A549 cells
  JOURNAL   Oncotarget 14, 261-275 (2023)
   PUBMED   36961882
  REMARK    GeneRIF: Downregulation of angulin-1/LSR induces malignancy via
            upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell
            metabolism in human lung adenocarcinoma A549 cells.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2961)
  AUTHORS   Koumangoye,R., Penny,P. and Delpire,E.
  TITLE     Loss of NKCC1 function increases epithelial tight junction
            permeability by upregulating claudin-2 expression
  JOURNAL   Am J Physiol Cell Physiol 323 (4), C1251-C1263 (2022)
   PUBMED   35968893
  REMARK    GeneRIF: Loss of NKCC1 function increases epithelial tight junction
            permeability by upregulating claudin-2 expression.
REFERENCE   5  (bases 1 to 2961)
  AUTHORS   Kinugasa,T., Tsunoda,T., Mizoguchi,E., Okada,T., Sudo,T.,
            Kawahara,A., Akiba,J. and Akagi,Y.
  TITLE     Chitinase 3-like 1, Carcinoembryonic Antigen-related Cell Adhesion
            Molecule 6, and Ectopic Claudin-2 in the Carcinogenic Processes of
            Ulcerative Colitis
  JOURNAL   Anticancer Res 42 (8), 4119-4127 (2022)
   PUBMED   35896264
  REMARK    GeneRIF: Chitinase 3-like 1, Carcinoembryonic Antigen-related Cell
            Adhesion Molecule 6, and Ectopic Claudin-2 in the Carcinogenic
            Processes of Ulcerative Colitis.
REFERENCE   6  (bases 1 to 2961)
  AUTHORS   Kniesel,U. and Wolburg,H.
  TITLE     Tight junctions of the blood-brain barrier
  JOURNAL   Cell Mol Neurobiol 20 (1), 57-76 (2000)
   PUBMED   10690502
  REMARK    Review article
REFERENCE   7  (bases 1 to 2961)
  AUTHORS   Itoh,M., Furuse,M., Morita,K., Kubota,K., Saitou,M. and Tsukita,S.
  TITLE     Direct binding of three tight junction-associated MAGUKs, ZO-1,
            ZO-2, and ZO-3, with the COOH termini of claudins
  JOURNAL   J Cell Biol 147 (6), 1351-1363 (1999)
   PUBMED   10601346
REFERENCE   8  (bases 1 to 2961)
  AUTHORS   Morita,K., Furuse,M., Fujimoto,K. and Tsukita,S.
  TITLE     Claudin multigene family encoding four-transmembrane domain protein
            components of tight junction strands
  JOURNAL   Proc Natl Acad Sci U S A 96 (2), 511-516 (1999)
   PUBMED   9892664
REFERENCE   9  (bases 1 to 2961)
  AUTHORS   Furuse,M., Fujita,K., Hiiragi,T., Fujimoto,K. and Tsukita,S.
  TITLE     Claudin-1 and -2: novel integral membrane proteins localizing at
            tight junctions with no sequence similarity to occludin
  JOURNAL   J Cell Biol 141 (7), 1539-1550 (1998)
   PUBMED   9647647
REFERENCE   10 (bases 1 to 2961)
  AUTHORS   Shelton,C., LaRusch,J. and Whitcomb,D.C.
  TITLE     Pancreatitis Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH,
            Gripp KW and Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   24624459
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA743944.1, AK075405.1 and
            AA973123.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jun 2, 2019 this sequence version replaced NM_020384.3.
            
            Summary: This gene product belongs to the claudin protein family
            whose members have been identified as major integral membrane
            proteins localized exclusively at tight junctions. Claudins are
            expressed in an organ-specific manner and regulate tissue-specific
            physiologic properties of tight junctions. This protein is
            expressed in the intestine. Alternatively spliced transcript
            variants with different 5' untranslated region have been found for
            this gene.[provided by RefSeq, Jan 2010].
            
            Transcript Variant: This variant represents the predominant
            transcript. Variants 1-3 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK075405.1, SRR1803611.186626.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03267767, SAMN03267768
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000336803.2/ ENSP00000336571.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-541               DA743944.1         39-579
            542-2524            AK075405.1         540-2522
            2525-2961           AA973123.1         12-448              c
FEATURES             Location/Qualifiers
     source          1..2961
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq22.3"
     gene            1..2961
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="claudin 2"
                     /db_xref="GeneID:9075"
                     /db_xref="HGNC:HGNC:2041"
                     /db_xref="MIM:300520"
     exon            1..150
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /inference="alignment:Splign:2.1.0"
     variation       6
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933373795"
     variation       10
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1349616421"
     variation       19
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933373893"
     variation       21
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:1933373948"
     variation       22
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:747506027"
     variation       30
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933374060"
     variation       31
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1449930218"
     variation       33
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1302495457"
     variation       36
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:4535876"
     variation       38
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933374292"
     variation       41
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933374349"
     variation       44
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1386959127"
     variation       46
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933374470"
     variation       50
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933374552"
     variation       55
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933374629"
     variation       56
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933374706"
     variation       57
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:926423276"
     variation       58
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:747399458"
     variation       59
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933374997"
     variation       63
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:181237145"
     variation       67
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1311042005"
     variation       75
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933375269"
     variation       76
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1456214960"
     variation       77
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933375404"
     variation       80
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1377301686"
     variation       82
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933375583"
     variation       94
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1388739944"
     variation       102
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1161218301"
     variation       103
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933375750"
     variation       110
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:1239223538"
     variation       111..114
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ggg"
                     /replace="gggg"
                     /db_xref="dbSNP:1933376046"
     variation       111
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1306952001"
     variation       112
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368168388"
     variation       113
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:980545342"
     variation       117
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:747689313"
     variation       120
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933376404"
     variation       121
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933376496"
     variation       123
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933376586"
     variation       124
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1246364177"
     variation       127
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:769246277"
     variation       130
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:960240977"
     variation       131
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:897746920"
     variation       141
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:773261761"
     variation       145
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:983725128"
     variation       147
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1270104162"
     variation       150
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:929266093"
     exon            151..2961
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /inference="alignment:Splign:2.1.0"
     variation       158
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1208549824"
     variation       160
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933493664"
     variation       162
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933493727"
     variation       163
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933493778"
     variation       168
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1471173288"
     variation       174
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933493911"
     variation       177
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:896896455"
     variation       183
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1191113016"
     variation       194
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1047512402"
     variation       196
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113920114"
     variation       197
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933494204"
     variation       204
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:768917467"
     variation       205
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2147795655"
     variation       207
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933494331"
     variation       208..213
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gaga"
                     /replace="gagaga"
                     /db_xref="dbSNP:1933494403"
     variation       211
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1187775552"
     variation       220
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:888663699"
     variation       229
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183323379"
     variation       231
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933494648"
     variation       234
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933494732"
     variation       235
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1204039009"
     misc_feature    236..238
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="upstream in-frame stop codon"
     variation       240
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1325476639"
     variation       247
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:998368831"
     variation       252
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1256397132"
     variation       261
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933495019"
     variation       262
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933495115"
     variation       264
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1253584271"
     variation       267
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1006233291"
     variation       268
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1297730800"
     variation       271
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933495534"
     variation       276
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1569290124"
     variation       278..307
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="cctgaagac"
                     /replace="cctgaagacaagggagcagtccctgaagac"
                     /db_xref="dbSNP:1933495744"
     variation       282..289
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="aag"
                     /replace="aagacaag"
                     /db_xref="dbSNP:1933495838"
     variation       287
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933495941"
     variation       289
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:747787877"
     variation       290
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933496132"
     variation       293
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1394396016"
     variation       294
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2147795696"
     variation       305
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2147795698"
     variation       307
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1244391417"
     variation       308
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:758062602"
     variation       316
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:778068250"
     variation       317
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:964209255"
     variation       326
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1392557192"
     variation       327
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:747351580"
     variation       328
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933496899"
     CDS             329..1021
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="SP82"
                     /codon_start=1
                     /product="claudin-2"
                     /protein_id="NP_065117.1"
                     /db_xref="CCDS:CCDS14524.1"
                     /db_xref="GeneID:9075"
                     /db_xref="HGNC:HGNC:2041"
                     /db_xref="MIM:300520"
                     /translation="
MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV"
     misc_feature    350..412
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     transmembrane region"
     misc_feature    395..871
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
     misc_feature    521..523
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="Paracellular cation selectivity.
                     /evidence=ECO:0000250|UniProtKB:O88552; propagated from
                     UniProtKB/Swiss-Prot (P57739.1); other site"
     misc_feature    572..634
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     transmembrane region"
     misc_feature    677..739
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     transmembrane region"
     misc_feature    815..877
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     transmembrane region"
     misc_feature    941..1018
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    983..985
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O88552; propagated from
                     UniProtKB/Swiss-Prot (P57739.1); phosphorylation site"
     misc_feature    995..997
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O88552; propagated from
                     UniProtKB/Swiss-Prot (P57739.1); phosphorylation site"
     misc_feature    1013..1018
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     Region: Interactions with TJP1, TJP2 and TJP3.
                     /evidence=ECO:0000250"
     variation       337
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1050947241"
     variation       341
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1339788803"
     variation       342
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1174689287"
     variation       351
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1165776868"
     variation       354
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:771374270"
     variation       355
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933497606"
     variation       356
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933497671"
     variation       357
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:776970197"
     variation       376
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1006766993"
     variation       379
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2046912333"
     variation       384
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:151003816"
     variation       386
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1441579095"
     variation       388
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:769979747"
     variation       390
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375239457"
     variation       392
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1225428237"
     variation       395
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:763199682"
     variation       409
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1322581753"
     variation       412
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1707367563"
     variation       415
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:141147283"
     variation       425
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:773012005"
     variation       426
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933498654"
     variation       427
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933498733"
     variation       433
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933498790"
     variation       436
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:760367001"
     variation       437
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:766238256"
     variation       439
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933499011"
     variation       445
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933499076"
     variation       447
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:753717485"
     variation       456
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933499204"
     variation       457
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:754968467"
     variation       473
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2147795815"
     variation       494
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1340271277"
     variation       495
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:764672394"
     variation       499
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1253322406"
     variation       502
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1197923613"
     variation       504
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1428983841"
     variation       508
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:923605747"
     variation       511
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1358867065"
     variation       513
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933499801"
     variation       521
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:387907423"
     variation       524
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:752232715"
     variation       529
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144975285"
     variation       532
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1602463347"
     variation       535
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:777266817"
     variation       547
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2147795842"
     variation       550
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369821153"
     variation       551
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138837133"
     variation       552
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147795850"
     variation       556
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:757556657"
     variation       572
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:750248939"
     variation       574
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933500564"
     variation       583
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199729528"
     variation       584
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1299571339"
     variation       586
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:781662821"
     variation       589
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:746302840"
     variation       595
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933500855"
     variation       610
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933500923"
     variation       614
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:774565639"
     variation       622
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1223885391"
     variation       626
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1285034346"
     variation       628
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:770428538"
     variation       630
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1194923745"
     variation       632
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:780242387"
     variation       640
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:916721142"
     variation       646
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:749402798"
     variation       651
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:768907606"
     variation       652
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147795897"
     variation       662
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1163686076"
     variation       663
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:774406442"
     variation       665
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:762164452"
     variation       666
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:770621723"
     variation       673
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:776503740"
     variation       675
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2147795915"
     variation       681
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1371738496"
     variation       682
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1446301117"
     variation       684
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:759405019"
     variation       687
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1168737487"
     variation       688
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1421690119"
     variation       691
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:765178431"
     variation       694
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:752676378"
     variation       695
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:762416149"
     variation       696
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:763723377"
     variation       697
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:751157579"
     variation       706
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1046516234"
     variation       715
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1180765203"
     variation       716
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1405527623"
     variation       725
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:756945099"
     variation       727
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1324491659"
     variation       734
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:867807470"
     variation       737
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933503017"
     variation       745
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933503085"
     variation       747
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1602463484"
     variation       750
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1226193123"
     variation       751
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1179022340"
     variation       756
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:373340705"
     variation       759
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:781343821"
     variation       761
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1343608436"
     variation       762
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200980922"
     variation       766
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:756640886"
     variation       772
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933503740"
     variation       774
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1490646672"
     variation       776
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1569290268"
     variation       777
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1225424186"
     variation       784
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:773581067"
     variation       790
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:140513089"
     variation       801
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150418351"
     variation       802
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1248266075"
     variation       808
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1194085483"
     variation       809
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1555979575"
     variation       814
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933504527"
     variation       815
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:940952718"
     variation       819
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1602463548"
     variation       820
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933504729"
     variation       824
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:768614767"
     variation       831
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:770506958"
     variation       832
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1423720929"
     variation       838
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933504949"
     variation       846
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2147796017"
     variation       850
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:387907422"
     variation       853
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1240174457"
     variation       855
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1337976305"
     variation       859
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933505157"
     variation       867
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933505232"
     variation       884
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1330462225"
     variation       888
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377500294"
     variation       891
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:779109711"
     variation       898
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933505552"
     variation       899
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:748262983"
     variation       900
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138227214"
     variation       901
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:918298567"
     variation       908
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933505877"
     variation       911
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1420501590"
     variation       913
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:776235840"
     variation       914
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371377414"
     variation       916
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200850588"
     variation       918
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:941607638"
     variation       921
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1007147163"
     variation       926
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:769614194"
     variation       928
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1043568277"
     variation       929
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:775398321"
     variation       936
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933506655"
     variation       943
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:149607136"
     variation       949
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1365377833"
     variation       950
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:763452096"
     variation       951
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:751085480"
     variation       954
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933507064"
     variation       958
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933507141"
     variation       962
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:767221740"
     variation       967
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:903761545"
     variation       973
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:750149991"
     variation       974
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:144353049"
     variation       988
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:752176611"
     variation       993
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933507602"
     variation       996
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1463118604"
     variation       1000
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:754385986"
     variation       1002
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:755524810"
     variation       1003
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933507919"
     variation       1009
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:778796184"
     variation       1011
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933508060"
     variation       1012
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:748294630"
     variation       1014
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933508203"
     variation       1023
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:758454165"
     variation       1029
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199803730"
     variation       1031
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1183247319"
     variation       1032
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1487375584"
     variation       1033
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:747295372"
     variation       1039
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1446531289"
     variation       1041..1046
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ggggg"
                     /replace="gggggg"
                     /db_xref="dbSNP:1933508658"
     variation       1041
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1013632794"
     variation       1046
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1361984240"
     variation       1047
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933508798"
     variation       1052
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1024159272"
     variation       1053
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:769560991"
     variation       1057..1060
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="tg"
                     /replace="tgtg"
                     /db_xref="dbSNP:753226000"
     variation       1069
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1223314804"
     variation       1076
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="cc"
                     /db_xref="dbSNP:1933509110"
     variation       1078
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:763951976"
     variation       1079
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933509164"
     variation       1081
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1029793431"
     variation       1082
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933509285"
     variation       1085
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933509379"
     variation       1087
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933509430"
     variation       1088
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933509489"
     variation       1094
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:1933509549"
     variation       1095
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933509613"
     variation       1102
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933509661"
     variation       1109
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:760647123"
     variation       1115
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:985353276"
     variation       1116
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1016465854"
     variation       1124
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933509934"
     variation       1128
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1602463748"
     variation       1129
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933510046"
     variation       1132
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1187932935"
     variation       1134..1138
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ga"
                     /replace="gagga"
                     /db_xref="dbSNP:1173935028"
     variation       1140
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933510341"
     variation       1164
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1469120360"
     variation       1165
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933510483"
     variation       1170
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1430213662"
     variation       1178
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374633456"
     variation       1181
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1427753487"
     variation       1184
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191880523"
     variation       1186
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933510708"
     variation       1188
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:767031230"
     variation       1189
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933510890"
     variation       1193
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933510931"
     variation       1196
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:918215242"
     variation       1198
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933511016"
     variation       1212
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933511073"
     variation       1221
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:933666615"
     variation       1223
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933511171"
     variation       1224
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:754393914"
     variation       1228
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:910947988"
     variation       1232
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1602463797"
     variation       1233
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1030639588"
     variation       1235..1240
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ct"
                     /replace="ctttct"
                     /db_xref="dbSNP:754666261"
     variation       1238..1240
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="t"
                     /replace="tct"
                     /db_xref="dbSNP:2147796201"
     variation       1246
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376522492"
     variation       1247
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:942487142"
     variation       1251
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1349375470"
     variation       1252
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1043537300"
     variation       1254
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:989380513"
     variation       1265
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:755453835"
     variation       1269
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1363071254"
     variation       1270
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1225026609"
     variation       1274
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1359444888"
     variation       1280
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1269010559"
     variation       1282
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200371519"
     variation       1283
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1328074593"
     variation       1288
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1334666073"
     variation       1305
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1296027863"
     variation       1314
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1362142694"
     variation       1320
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933512431"
     variation       1323
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:16987204"
     variation       1325
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1023597988"
     variation       1327
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:781381086"
     variation       1328
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933512714"
     variation       1338
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1052307518"
     variation       1344
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933512824"
     variation       1346
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1288471544"
     variation       1371
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:779363433"
     variation       1374
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:981899851"
     variation       1377
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:927804897"
     variation       1381
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1476460542"
     variation       1383
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:748203460"
     variation       1386
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2147796247"
     variation       1387
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1183586731"
     variation       1389..1392
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace=""
                     /replace="gacc"
                     /db_xref="dbSNP:1933513354"
     variation       1389
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183625207"
     variation       1391
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933513405"
     variation       1392
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:930046697"
     variation       1393..1396
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ctct"
                     /replace="ctctct"
                     /db_xref="dbSNP:1933513537"
     variation       1424
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1485418465"
     variation       1433..1434
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:1933513676"
     variation       1435
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1853350578"
     variation       1437
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933513733"
     variation       1441
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933513799"
     variation       1452..1454
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ggg"
                     /replace="gggg"
                     /db_xref="dbSNP:1202868595"
     variation       1456..1460
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ag"
                     /replace="aggag"
                     /db_xref="dbSNP:1933513925"
     variation       1460
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:983299811"
     variation       1461
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933514064"
     variation       1468
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933514134"
     variation       1471..1474
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ttt"
                     /replace="tttt"
                     /replace="ttttt"
                     /db_xref="dbSNP:778150160"
     variation       1474
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933514291"
     variation       1477
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1214619280"
     variation       1478
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:572499503"
     variation       1479
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933514454"
     variation       1480
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1312821032"
     variation       1487
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933514576"
     variation       1491
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933514632"
     variation       1494
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1023666118"
     variation       1510
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:1933514742"
     variation       1520
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1602463942"
     variation       1528
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:941404389"
     variation       1541
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:749662629"
     variation       1543
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933515021"
     variation       1544
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933515108"
     variation       1549
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933515197"
     variation       1552
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1439784475"
     variation       1554
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933515388"
     variation       1556
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:905258957"
     variation       1558
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1354137394"
     variation       1561
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933515650"
     variation       1568
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1006350382"
     variation       1575
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1329843379"
     variation       1583
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933515911"
     variation       1584
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1016436169"
     variation       1585
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:962214642"
     variation       1586
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933516155"
     variation       1588
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933516253"
     variation       1589
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933516352"
     variation       1590
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1383529237"
     variation       1598..1601
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="aaaa"
                     /replace="aaaaa"
                     /db_xref="dbSNP:1933516526"
     variation       1604
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1163020561"
     variation       1610
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:972284147"
     variation       1611
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1039924368"
     variation       1613
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933516954"
     variation       1615
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933517034"
     variation       1616
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1445097089"
     variation       1619
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933517192"
     variation       1620
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:771330771"
     variation       1624
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933517400"
     variation       1627
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:955010979"
     variation       1631
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933517593"
     variation       1646
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:986852663"
     variation       1648
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933517806"
     variation       1653
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:910927841"
     variation       1658
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:900060604"
     variation       1659
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933518128"
     variation       1665
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1403729492"
     variation       1669
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1288879315"
     variation       1671
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933518404"
     variation       1672
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933518500"
     variation       1681
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1128218"
     variation       1687
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1346071962"
     variation       1688
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933518864"
     variation       1689..1697
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="aaaaa"
                     /replace="aaaaaaaa"
                     /replace="aaaaaaaaa"
                     /replace="aaaaaaaaaa"
                     /db_xref="dbSNP:759145216"
     variation       1690
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1456924720"
     variation       1696
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1318869665"
     variation       1697
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:867306371"
     variation       1698
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933519422"
     variation       1719
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933519512"
     variation       1726
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2147796376"
     variation       1727
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1385471805"
     variation       1731
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1453943065"
     variation       1733
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933519790"
     variation       1736
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:771733386"
     variation       1738
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1284177053"
     variation       1744
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933520057"
     variation       1749
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933520153"
     variation       1752
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41309528"
     variation       1756
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:760105451"
     variation       1760
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1302584554"
     variation       1761
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:972096283"
     variation       1762
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933520702"
     variation       1764
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:979159103"
     variation       1765
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:1713557154"
     variation       1768
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:764086272"
     variation       1769
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933520976"
     variation       1770..1780
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gaggaaagcac"
                     /replace="gaggaaagcacgaggaaagcac"
                     /db_xref="dbSNP:1284505266"
     variation       1781
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933521152"
     variation       1790
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933521234"
     variation       1791..1797
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="aaga"
                     /replace="aagaaga"
                     /db_xref="dbSNP:1157601776"
     variation       1795
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1327975160"
     variation       1801..1802
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gg"
                     /replace="ggg"
                     /db_xref="dbSNP:200233084"
     variation       1804
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1179326894"
     variation       1810
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1473347848"
     variation       1811
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147796421"
     variation       1818
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:761681083"
     variation       1822
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1221064448"
     variation       1823
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:765163859"
     variation       1827
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933521807"
     variation       1830..1835
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gactcc"
                     /replace="gactccgactcc"
                     /db_xref="dbSNP:1267143367"
     variation       1832
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933521924"
     variation       1841
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:935183925"
     variation       1860
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:903364031"
     variation       1861
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933522111"
     variation       1863
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933522165"
     variation       1870
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933522215"
     variation       1871
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933522272"
     variation       1876
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933522334"
     variation       1881
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1235706727"
     variation       1886
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1052276795"
     variation       1887
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933522527"
     variation       1895
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1471850304"
     variation       1896
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7883582"
     variation       1897
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1825830632"
     variation       1904
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1282931637"
     variation       1911
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933522778"
     variation       1913
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933522840"
     variation       1918
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1405594851"
     variation       1924
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1347536629"
     variation       1930
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:999272013"
     variation       1931..1942
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ggcta"
                     /replace="ggctaagggcta"
                     /db_xref="dbSNP:1453596416"
     variation       1935..1936
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:1933523254"
     variation       1938
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933523335"
     variation       1946
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933523431"
     variation       1951
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:980248325"
     variation       1952
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:949356395"
     variation       1962
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933523685"
     variation       1963..1964
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:1031193019"
     variation       1965
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933523876"
     variation       1968
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1045470856"
     variation       1970
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933524079"
     variation       1978
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933524166"
     variation       1979
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933524242"
     variation       1980
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933524337"
     variation       1982
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:755206308"
     variation       1988
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1468618129"
     variation       1989
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:905228764"
     variation       2000
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1198325716"
     variation       2006
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1006278229"
     variation       2009
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933524835"
     variation       2010
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933524910"
     variation       2013
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:893472718"
     variation       2022
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1268771437"
     variation       2024..2027
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ggg"
                     /replace="gggg"
                     /db_xref="dbSNP:755582862"
     variation       2024
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1184260913"
     variation       2025
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1602464146"
     variation       2030
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933525425"
     variation       2031
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1010613160"
     variation       2035
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187325704"
     variation       2038
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1157242320"
     variation       2043
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2081095094"
     variation       2045
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933525787"
     variation       2047
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73533029"
     variation       2053
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:969267590"
     variation       2054
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933526083"
     variation       2057
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933526166"
     variation       2059
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933526247"
     variation       2060
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:1933526323"
     variation       2063
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933526405"
     variation       2068
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1262741766"
     variation       2070
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1602464170"
     variation       2071
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192635116"
     variation       2074
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933526678"
     variation       2077
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:982037199"
     variation       2087
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933526836"
     variation       2089
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:993651568"
     variation       2092
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933527013"
     variation       2093..2100
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gt"
                     /replace="gtgggtgt"
                     /db_xref="dbSNP:1034844997"
     variation       2097
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:778318354"
     variation       2103
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933527311"
     variation       2104
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933527391"
     variation       2107
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1602464186"
     variation       2112
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933527525"
     variation       2115
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1293477754"
     variation       2125..2129
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ccccc"
                     /replace="cccccc"
                     /db_xref="dbSNP:1334078065"
     variation       2125
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933527649"
     variation       2127
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1030521600"
     variation       2130
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933527836"
     variation       2132
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:951313095"
     variation       2136
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933527969"
     variation       2141
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933528029"
     variation       2145
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1602464204"
     variation       2146
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:982884104"
     variation       2146
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:955125195"
     variation       2151
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1445010608"
     variation       2153
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933528313"
     variation       2156
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1177620206"
     variation       2163
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1279565556"
     variation       2165
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:749797089"
     variation       2166
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:941456311"
     variation       2172
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933528785"
     variation       2174
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1167642904"
     variation       2176
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1007842765"
     variation       2177..2183
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="cccccc"
                     /replace="ccccccc"
                     /replace="cccccccc"
                     /replace="ccccccccc"
                     /db_xref="dbSNP:777233825"
     variation       2178
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1459801475"
     variation       2179
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1242240915"
     variation       2181
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1018323664"
     variation       2182
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933529621"
     variation       2183
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933529693"
     variation       2184
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1226138814"
     variation       2186
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184610738"
     variation       2191
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933529994"
     variation       2192
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933530082"
     variation       2193
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1249886275"
     variation       2198
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:779196711"
     variation       2200
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1308223987"
     variation       2207..2210
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ag"
                     /replace="agag"
                     /db_xref="dbSNP:1933530456"
     variation       2211
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147829672"
     variation       2219
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933530703"
     variation       2222
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:921283334"
     variation       2223
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1439418990"
     variation       2224
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2147796635"
     variation       2229
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1337754013"
     variation       2234
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1205169441"
     variation       2235
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1403875070"
     variation       2236
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141297568"
     variation       2239
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933531384"
     variation       2246
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:934216616"
     variation       2250
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:956485078"
     variation       2251
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1051814528"
     variation       2252
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:924786790"
     variation       2259..2263
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gtcca"
                     /replace="gtccagtcca"
                     /db_xref="dbSNP:1442626557"
     variation       2259
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1384560660"
     variation       2263
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:775069708"
     variation       2264
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1425380488"
     variation       2266
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:987916679"
     variation       2267
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:917799064"
     variation       2268
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933532433"
     variation       2276
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1276782566"
     variation       2286
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933532617"
     variation       2288
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1431803991"
     variation       2293
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:949321986"
     variation       2301
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1480960024"
     variation       2303
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1052185255"
     variation       2308
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:893519288"
     variation       2316
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1010676925"
     variation       2320
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1044998511"
     variation       2328
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:926579900"
     variation       2329
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145166443"
     variation       2334..2338
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="tgt"
                     /replace="tgtgt"
                     /db_xref="dbSNP:1304391959"
     variation       2336
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:878973134"
     variation       2338
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2063898797"
     variation       2357
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1044721618"
     variation       2360
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:904886092"
     variation       2361
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933533559"
     variation       2362
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1309268282"
     variation       2363
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933533682"
     variation       2368
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1422270796"
     variation       2369
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1037732398"
     variation       2370
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1163841985"
     variation       2374
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933533914"
     variation       2375
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:897892712"
     variation       2379
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1035386486"
     variation       2383
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:745435515"
     variation       2394
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933534152"
     variation       2410
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933534216"
     variation       2412..2414
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="aga"
                     /db_xref="dbSNP:1180829728"
     variation       2423
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1419855621"
     variation       2428
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1822830889"
     variation       2429
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:951237979"
     variation       2434
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:993619322"
     variation       2435
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1197334973"
     variation       2437
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1602464404"
     variation       2447..2449
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="tt"
                     /replace="ttt"
                     /db_xref="dbSNP:771337109"
     variation       2448
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933534669"
     variation       2451
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1330173589"
     variation       2453
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1369382611"
     variation       2461
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1407504770"
     variation       2462
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1304580367"
     variation       2468
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933534977"
     variation       2469
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1293133173"
     variation       2471
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:769158456"
     variation       2472
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1004419212"
     variation       2473
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1260436024"
     variation       2475
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933535250"
     variation       2481
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373807733"
     variation       2484
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933535357"
     variation       2491
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186720703"
     variation       2492
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1016771138"
     variation       2494
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1289881056"
     variation       2497
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1402553812"
     variation       2503
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933535555"
     variation       2506
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933535616"
     variation       2518
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1344384425"
     variation       2519
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1323660980"
     variation       2520
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1406953096"
     variation       2523
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:780022444"
     variation       2532
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933535890"
     variation       2538
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147796780"
     variation       2544
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1157729882"
     variation       2545
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1457615982"
     variation       2549
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1232079457"
     variation       2553
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1685133009"
     variation       2554
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933536131"
     variation       2560
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201099546"
     variation       2562
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:975483117"
     variation       2566
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1272814342"
     variation       2567
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933536405"
     variation       2568
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:890637044"
     variation       2573
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:749161015"
     variation       2579
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933536659"
     variation       2583
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1008185180"
     variation       2585
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:921252090"
     variation       2591
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1261703235"
     variation       2592
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:768441150"
     variation       2598
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933537048"
     variation       2599
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1206059325"
     variation       2600
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933537240"
     variation       2603
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933537310"
     variation       2612
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1331747466"
     variation       2618
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1269618855"
     variation       2621
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933537582"
     variation       2625
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933537675"
     variation       2631
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1221244497"
     variation       2632
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933537835"
     variation       2637
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:963653805"
     variation       2639
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2147796834"
     variation       2640
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933538005"
     variation       2644
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192199825"
     variation       2645
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:774091882"
     variation       2646
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1273876982"
     variation       2647
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:748340523"
     variation       2648
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:772383789"
     variation       2657
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:956455777"
     variation       2664
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:955400201"
     variation       2665
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1203177441"
     variation       2667
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1271156409"
     variation       2673
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933538927"
     variation       2676
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:776602466"
     variation       2680
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1317603558"
     variation       2685
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1198463696"
     variation       2686
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1390634814"
     variation       2691
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933539272"
     variation       2694
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1174004516"
     variation       2695
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1266588979"
     variation       2696
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933539561"
     variation       2702
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1426173249"
     variation       2703
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1358982432"
     variation       2707
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:761802048"
     variation       2713
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933539879"
     variation       2718
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1174338721"
     variation       2721
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:917711333"
     variation       2722
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933540148"
     variation       2726
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:773273862"
     variation       2733
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933540329"
     variation       2737
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933540390"
     variation       2742
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:987070328"
     variation       2743
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1245296801"
     variation       2748
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:970591926"
     variation       2751..2755
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="cccc"
                     /replace="ccccc"
                     /db_xref="dbSNP:1189847520"
     variation       2759
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:981065507"
     variation       2760
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1241616633"
     variation       2761
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:926512216"
     variation       2764
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:941948344"
     variation       2769
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933541210"
     variation       2771
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1169752336"
     variation       2772
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1602464597"
     variation       2775
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933541482"
     variation       2776..2781
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ctt"
                     /replace="cttctt"
                     /db_xref="dbSNP:1933541567"
     variation       2778
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:934938927"
     variation       2779
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147588227"
     variation       2780
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1164875011"
     variation       2786
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:919291399"
     variation       2791
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1228977913"
     variation       2807
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367974655"
     variation       2812
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:773087022"
     variation       2813
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:929340273"
     variation       2814..2819
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="tt"
                     /replace="ttattt"
                     /db_xref="dbSNP:1933542357"
     variation       2815
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1451674765"
     variation       2816
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933542539"
     variation       2819..2831
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="tgtgtgtgtgt"
                     /replace="tgtgtgtgtgtgt"
                     /replace="tgtgtgtgtgtgtgt"
                     /db_xref="dbSNP:766584577"
     variation       2827
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:904856493"
     variation       2829
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:760876206"
     variation       2832
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1602464638"
     variation       2838
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933543075"
     variation       2842
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:762850832"
     variation       2849
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933543241"
     variation       2850
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1051859941"
     variation       2851
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933543407"
     variation       2856
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933543496"
     variation       2861
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933543584"
     variation       2862
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1327946869"
     variation       2870
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1395792399"
     variation       2871
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1169313136"
     variation       2880
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:767777714"
     variation       2881..2892
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ct"
                     /replace="ctagacctctct"
                     /db_xref="dbSNP:1933544046"
     variation       2882
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1451841557"
     variation       2888
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1003653062"
     variation       2897..2901
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ccccc"
                     /replace="cccccc"
                     /db_xref="dbSNP:1183348344"
     variation       2898
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147796960"
     variation       2901
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:890596206"
     variation       2917
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933544507"
     variation       2921
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1602464670"
     variation       2922
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1473352127"
     variation       2925
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933544663"
     variation       2931
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933544718"
     variation       2932
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:752922976"
     variation       2936
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933544850"
     variation       2940
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933544927"
     regulatory      2941..2946
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="hexamer: AATAAA"
     variation       2958
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933544998"
     variation       2959
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1211868419"
     polyA_site      2961
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="major polyA site"
ORIGIN      
gcagatggattttgcaaagctgtggttaacgattagaaatcctttatcacctcagcccgtggccccttgtacttcgctcccctccctcaggatccctttctccctctccaggggcatctccccctccaaggctctgcaaagaactgccctgtcttctagatgccttcttgaggctgcttgtggccacccacagacacttgtaaggaggagagaagtcagcctggcagagagactctgaaatgagggattagaggtgttcaaggagcaagagcttcagcctgaagacaagggagcagtccctgaagacgcttctactgagaggtctgccatggcctctcttggcctccaacttgtgggctacatcctaggccttctggggcttttgggcacactggttgccatgctgctccccagctggaaaacaagttcttatgtcggtgccagcattgtgacagcagttggcttctccaagggcctctggatggaatgtgccacacacagcacaggcatcacccagtgtgacatctatagcacccttctgggcctgcccgctgacatccaggctgcccaggccatgatggtgacatccagtgcaatctcctccctggcctgcattatctctgtggtgggcatgagatgcacagtcttctgccaggaatcccgagccaaagacagagtggcggtagcaggtggagtctttttcatccttggaggcctcctgggattcattcctgttgcctggaatcttcatgggatcctacgggacttctactcaccactggtgcctgacagcatgaaatttgagattggagaggctctttacttgggcattatttcttccctgttctccctgatagctggaatcatcctctgcttttcctgctcatcccagagaaatcgctccaactactacgatgcctaccaagcccaacctcttgccacaaggagctctccaaggcctggtcaacctcccaaagtcaagagtgagttcaattcctacagcctgacagggtatgtgtgaagaaccaggggccagagctggggggtggctgggtctgtgaaaaacagtggacagcaccccgagggccacaggtgagggacactaccactggatcgtgtcagaaggtgctgctgaggatagactgactttggccattggattgagcaaaggcagaaatgggggctagtgtaacagcatgcaggttgaattgccaaggatgctcgccatgccagcctttctgttttcctcaccttgctgctcccctgccctaagtccccaaccctcaacttgaaaccccattcccttaagccaggactcagaggatccctttgccctctggtttacctgggactccatccccaaacccactaatcacatcccactgactgaccctctgtgatcaaagaccctctctctggctgaggttggctcttagctcattgctggggatgggaaggagaagcagtggcttttgtgggcattgctctaacctacttctcaagcttccctccaaagaaactgattggccctggaacctccatcccactcttgttatgactccacagtgtccagactaatttgtgcatgaactgaaataaaaccatcctacggtatccagggaacagaaagcaggatgcaggatgggaggacaggaaggcagcctgggacatttaaaaaaataaaaatgaaaaaaaaacccagaacccatttctcagggcactttccagaattctctcatatttgtgggctgggatcaagcctgcagcttgaggaaagcacaaggaaaggaaagaagatctggtggaaagctcaggtggcagcggactctgactccactgaggaactgcctcagaagctgcgatcacaactttggctgaagcccctgcctcactctagggcacctgacctggcctcttgcctaaaccacaaggctaagggctatagacaatggtttccttaggaacagtaaaccagtttttctagggatggcccttggctgggggatgacagtgtgggagctgtggggtactgaggaagacaccattccttgacggtgtctaagaagccaggtggatgtgtgtggtggctccagtgggtgtttctactctgccagtgagaggcagccccctagaaactcttcaggcgtaatggaaaatcagctcaaatgagatcaggcccccccagggtccacccacagagcactacagagcctctgaaagaccatagcaccaagcgagccccttcagattcccccactgtccatcggaagatgctccagagtggctagagggcatctaagggctccagcatggcatatccatgcccacggtgctgtgtccatgatctgagtgatagctgcactgctgcctgggattgcagctgaggtgggagtggagaatggttcccaggaagacagttccacctctaaggtccgaaaatgttccctttaccctggagtgggagtgaggggtcatacaccaaaggtattttccctcaccagtctaggcatgactggcttctgaaaaattccagcacacctcctcgaacctcattgtcagcagagagggcccatctgttgtctgtaacatgcctttcacatgtccaccttcttgccatgttccagctgctctcccaacctggaaggccgtctccccttagccaagtcctcctcaggcttggagaacttcctcagcgtcacctccttcattgagccttctctgatcactccatccctctcctacccctccctcccccaaccctcaatgtataaattgcttcttgatgcttagcattcacaatttttgattgatcgttatttgtgtgtgtgtgtccgatctcacaagtatattgtaaacccttcggtgggtgggggccatatcctagacctctctgtatcccccagactatctgtaacagtgccaggcacacagtaggtgatcaataaacacttgttgattgag
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]