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2024-04-24 21:28:46, GGRNA : RefSeq release 60 (20130726)
LOCUS NR_027791 3278 bp RNA linear PRI 16-JUL-2013
DEFINITION Homo sapiens long intergenic non-protein coding RNA 478
(LINC00478), transcript variant 2, non-coding RNA.
ACCESSION NR_027791
VERSION NR_027791.1 GI:239937465
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3278)
AUTHORS Kim DK, Cho MH, Hersh CP, Lomas DA, Miller BE, Kong X, Bakke P,
Gulsvik A, Agusti A, Wouters E, Celli B, Coxson H, Vestbo J, MacNee
W, Yates JC, Rennard S, Litonjua A, Qiu W, Beaty TH, Crapo JD,
Riley JH, Tal-Singer R and Silverman EK.
CONSRTM ECLIPSE, ICGN, and COPDGene Investigators
TITLE Genome-wide association analysis of blood biomarkers in chronic
obstructive pulmonary disease
JOURNAL Am. J. Respir. Crit. Care Med. 186 (12), 1238-1247 (2012)
PUBMED 23144326
REFERENCE 2 (bases 1 to 3278)
AUTHORS Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
Gibbs,R.A. and Butte,N.F.
TITLE Novel genetic loci identified for the pathophysiology of childhood
obesity in the Hispanic population
JOURNAL PLoS ONE 7 (12), E51954 (2012)
PUBMED 23251661
REFERENCE 3 (bases 1 to 3278)
AUTHORS Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B,
Yusuf S, Gerstein HC, Engert JC and Anand S.
CONSRTM DREAM investigators
TITLE Variation at the NFATC2 locus increases the risk of
thiazolidinedione-induced edema in the Diabetes REduction
Assessment with ramipril and rosiglitazone Medication (DREAM) study
JOURNAL Diabetes Care 33 (10), 2250-2253 (2010)
PUBMED 20628086
REMARK GeneRIF: Observational study of gene-disease association,
gene-environment interaction, and pharmacogenomic / toxicogenomic.
(HuGE Navigator)
REFERENCE 4 (bases 1 to 3278)
AUTHORS Mick,E., Todorov,A., Smalley,S., Hu,X., Loo,S., Todd,R.D.,
Biederman,J., Byrne,D., Dechairo,B., Guiney,A., McCracken,J.,
McGough,J., Nelson,S.F., Reiersen,A.M., Wilens,T.E., Wozniak,J.,
Neale,B.M. and Faraone,S.V.
TITLE Family-based genome-wide association scan of
attention-deficit/hyperactivity disorder
JOURNAL J Am Acad Child Adolesc Psychiatry 49 (9), 898-905 (2010)
PUBMED 20732626
REFERENCE 5 (bases 1 to 3278)
AUTHORS Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt
TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M,
Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ,
Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S,
Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD,
Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE
and Hingorani AD.
CONSRTM ASCOT investigators; NORDIL investigators; BRIGHT Consortium
TITLE Gene-centric association signals for lipids and apolipoproteins
identified via the HumanCVD BeadChip
JOURNAL Am. J. Hum. Genet. 85 (5), 628-642 (2009)
PUBMED 19913121
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 3278)
AUTHORS Gardiner,K., Slavov,D., Bechtel,L. and Davisson,M.
TITLE Annotation of human chromosome 21 for relevance to Down syndrome:
gene structure and expression analysis
JOURNAL Genomics 79 (6), 833-843 (2002)
PUBMED 12036298
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
CF135139.1, BC130602.1 and AP000473.2.
Transcript Variant: This variant (2) differs in the 5' region and
lacks an internal exon in the 3' region, compared to variant 1.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
##Evidence-Data-START##
Transcript exon combination :: AL700268.1, BM194465.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082, ERS025084 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-16 CF135139.1 8-23
17-497 BC130602.1 1-481
498-3278 AP000473.2 216-2996
FEATURES Location/Qualifiers
source 1..3278
/organism="Homo sapiens"
/mol_type="transcribed RNA"
/db_xref="taxon:9606"
/chromosome="21"
/map="21q21.1"
gene 1..3278
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/note="long intergenic non-protein coding RNA 478"
/db_xref="GeneID:388815"
/db_xref="HGNC:1274"
misc_RNA 1..3278
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/product="long intergenic non-protein coding RNA 478,
transcript variant 2"
/db_xref="GeneID:388815"
/db_xref="HGNC:1274"
exon 1..255
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/inference="alignment:Splign:1.39.8"
variation 33
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:377556417"
variation 38
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="g"
/db_xref="dbSNP:16994440"
variation 75
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:368620969"
variation 92
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:143151691"
variation 108
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:148215361"
variation 109
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:62219500"
variation 161
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="g"
/db_xref="dbSNP:372893223"
variation 183
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:150750465"
variation 184
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:139060431"
variation 205
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="c"
/db_xref="dbSNP:144814897"
variation 250
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:146380740"
exon 256..315
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/inference="alignment:Splign:1.39.8"
variation 260
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:139786545"
variation 262
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:144391170"
variation 309
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="c"
/db_xref="dbSNP:368911017"
exon 316..387
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/inference="alignment:Splign:1.39.8"
variation 321
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:145371190"
variation 329
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:148738419"
variation 362..364
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace=""
/replace="aag"
/db_xref="dbSNP:199686904"
variation 369
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:374168603"
variation 377
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:377098625"
exon 388..436
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/inference="alignment:Splign:1.39.8"
variation 395
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:147246782"
exon 437..497
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/inference="alignment:Splign:1.39.8"
variation 444
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:375104814"
exon 498..3278
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/inference="alignment:Splign:1.39.8"
variation 582
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:79969089"
variation 585
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:181829513"
variation 613
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:76221349"
variation 627
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:138525130"
variation 668
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:56083400"
variation 693
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="g"
/db_xref="dbSNP:141583376"
variation 737
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="c"
/db_xref="dbSNP:113878929"
variation 774
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="g"
/db_xref="dbSNP:185367465"
variation 806
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="c"
/db_xref="dbSNP:148431020"
variation 888
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="g"
/replace="t"
/db_xref="dbSNP:189792869"
variation 915
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:142904378"
variation 927
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="g"
/db_xref="dbSNP:150672285"
variation 988
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:79641229"
variation 989
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:182786681"
variation 1064
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="g"
/replace="t"
/db_xref="dbSNP:144910494"
variation 1071
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:187175616"
variation 1131
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:368035548"
variation 1138
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:147967639"
variation 1145
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:141541363"
variation 1173
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:192059958"
variation 1175
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="c"
/db_xref="dbSNP:183477283"
variation 1179
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:188475535"
variation 1304
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:371964594"
variation 1344..1345
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace=""
/replace="tg"
/db_xref="dbSNP:371895006"
variation 1355
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:77585114"
variation 1393
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:112744752"
variation 1411
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:2226435"
variation 1462
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="g"
/db_xref="dbSNP:75217989"
variation 1466
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="g"
/db_xref="dbSNP:371336983"
variation 1507
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:111312706"
variation 1509
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:377294423"
variation 1633
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="g"
/db_xref="dbSNP:145229615"
variation 1644
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:9284477"
variation 1734
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="t"
/db_xref="dbSNP:77085254"
variation 1754
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="t"
/db_xref="dbSNP:73891630"
variation 1812
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="t"
/db_xref="dbSNP:9976817"
variation 1846
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:149171029"
variation 1852
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:377611210"
variation 1895..1896
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace=""
/replace="g"
/db_xref="dbSNP:148668068"
variation 1902
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:193123000"
variation 1946
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:143305143"
variation 1961
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:117398552"
variation 1963
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:75732738"
variation 2002
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:184578703"
variation 2198
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="t"
/db_xref="dbSNP:186748256"
variation 2199
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:148030533"
variation 2258
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="g"
/replace="t"
/db_xref="dbSNP:141055187"
variation 2308
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:117053721"
variation 2318..2320
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace=""
/replace="ttc"
/db_xref="dbSNP:142143973"
variation 2320..2322
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace=""
/replace="ctt"
/db_xref="dbSNP:371330516"
variation 2339
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:35137281"
variation 2356
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:201405636"
variation 2440..2441
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace=""
/replace="t"
/db_xref="dbSNP:34791936"
variation 2642
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:144882834"
variation 2701
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:116481940"
variation 2791
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:62222249"
variation 2799
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="g"
/replace="t"
/db_xref="dbSNP:373264853"
variation 2941
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="g"
/db_xref="dbSNP:9305770"
variation 3029
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="t"
/db_xref="dbSNP:191263808"
variation 3160
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:2823908"
variation 3171..3172
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace=""
/replace="a"
/replace="c"
/db_xref="dbSNP:36068540"
variation 3173..3174
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace=""
/replace="c"
/db_xref="dbSNP:68111259"
variation 3173
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="c"
/db_xref="dbSNP:80037519"
variation 3185
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:141490819"
variation 3255
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="c"
/replace="t"
/db_xref="dbSNP:184131334"
variation 3256
/gene="LINC00478"
/gene_synonym="C21orf34; C21orf35; FLJ38295"
/replace="a"
/replace="c"
/db_xref="dbSNP:150723595"
ORIGIN
tgaactgaaagaacaaatcgcctacttcaggcggtggcaagcgtatggaaattatattagaacttcagcaaagtgcacagctgcataatagagaagccggcactcagattgacaggcaaataagccagcttgtggaaggggcctctgggtggcagctctgggcttttgggtgttggacaaccataggcaaaactgaaatggaacaggggcagaaaatagcacacttttactctacgcaactgttgctttttcatgatcttcaggaattttactgggataattatccaaataaattgcaagcattctatccaaatggagctctttctgagatgaagagaattctcaatgtcaagatttgaacaagaagagaatggaatacacaatatggacatccataaaaattcatcagagagcattttactactgagctgcaaagggaaaaacttaaaatggatatgaaaagtgaagaaagtgatcataggagaaaaccatttcagatgacaagagcacctcaaaggcagcagcctcaaggagcagccatggccccagacttgtcgcacggatgcagaaaacttaatggaggaggctgaggtcagaatgggaagagtttttaaaaaataaaaaggggagctaatatgtgaggaactgattgctgtgcattattttccactgaacagaccttcttttaacttctaatctcaagcacatagcagctgttgttttcatattaaagatcagtaagtgtttgttgaatgaatgtataaattcttccccaatctctgttccatgtaataagaactaagttagcattcaattataaagaggacttagaaagtctgcagacatttttgatcaaaaatccttttaactgtcttcttatggttcccggtaacacctaagcccaaaaaactcaggtcatttcttgcctgtactgttgcaatagcctcataataactagtcttctcctttatcaaccacagtcgtctccgctacacaaagaagagagggtgctaatctaaagtgtaaattattttaaatcagcacccttcttgtaatttcccagtggtttttcctgtcataagaataacatgcaaaattccttgcttgcaaagccaggtatgaccttgccccgtctaccttactggcatcgtctctcatgactcttcccctttttcactctccatcttgccttttcccaaccatgcctgctagtgagccttagcccttgtgttttctctgccagggatgcatgactggcttctttactttattctgatctctctgctcaaatgtcatctttttagagatagctttcctaaacatctttaaaagtaccccatgaactgtgaaacacctttcctgctttttcttcatagtacttatcacttcctgatattatgttagacaacaagcaaataagtatatgctgttcccactaaaatataagctccatttgaacaggagccttgattattcctgagtatacccctagtgcccagaacctagtagggctttaataaatattagattcatttgttgaatgaaaaaatgaatgaataattgaataaagatatccaggtagagtgtccgggcagcccaacctatgtgaagccagtacaagaatgtttctgtgacatagtgagcgcaattattcctctaaatgatgaacttgcatgagtacacaaggataaaattaagcacgtagtttagatttctgcaagtctcttcctcagattgaggaaaaacaaagaaattgagcttattctcacctcattcttacatgaactaaatccagaataaagcatcatttaaataccaagcacatccctacctcagccactcatggaatactttatctgtaaagggacagatagatagtaaatatttttggctttggggaccgtacagtctgtgtcgccactactcagcacttctgttgaggtgtggaatcagccctagacaacacataaacaaatgggtgtggctgtgttccaataaaatgttatttataaaactaggaaatcagcagatttagtccacaggctgtagtttgctgacccttgaattagagagtcttccccaaatcctcttcccaagttattgaaagaatgcccataggaccatagctccctcacctggttctttcaagaaatgagacaaattcagggatggttggagggtggaacgcctacctgtgacatgactattgagcctgatttctttccttttatctctttaaagtgagtcaggtcttaactttaaactgtctctaaagtggcaataactgggccatgtcaaatactcccaatgacaaaatttcttcttggagaatgaatgagggttgcatacagtggtgtgttggtaaatgtttagcaactggctctcttactgatttctgtagtgtaaattctcccatcctggccatctgaaactaccaatatgatgtcacttgatgtagagttgggaaaagacagtctcttgaataagtatgagctggttccagcccactgctgaacacatatttaaaagctacaatagctctgctcactgccattgcagagtctggaggaaagagtagcaggcttgataggagcaattggctgaataatcttttgcaatgccaataaataatgaaaaagtatataaatataacgctgtatagaaagctctcaagttcagtgtttggttaaaatacatactcagtaaatggtagctattattgtcttagtttaagttattgcaagcattaaaattaaatgtttagctacagactcaatccagttttaatgtcattgtgttaataaggcctcttaacattgaagcaacaaagataaaggaatttttttgtagctattcacgattctgcccagctcaaggtaaagatagcaacaaaatactccaaccagaataaaagaagtctccacttgactgcagctcttcgcaacacttcacaagggtcaagctgtgttagtttccttcagtgttaaacagaatgcatcttaagagaatagttcaattattgattgaatagtaggttcaagttgactataatcccaactaatacactctaagaccagggatgggccgacagaagggtaaagttttccactcaagtctcgaggcaaacactcagatagaagtagtaatatggatgccttctattatttggtcaatacaatactgttccagcccagttgtgcaaaactggtgaaataaaaggcaaaaatattgacaacagtttgggtaactggattccaaaatgggcatccatctaagag
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