LOCUS       NR_027450               3106 bp    RNA     linear   PRI 16-JUL-2013
DEFINITION  Homo sapiens family with sequence similarity 186, member B
            (FAM186B), transcript variant 2, non-coding RNA.
ACCESSION   NR_027450
VERSION     NR_027450.1  GI:226246614
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3106)
  AUTHORS   Simpson,J.C., Wellenreuther,R., Poustka,A., Pepperkok,R. and
            Wiemann,S.
  TITLE     Systematic subcellular localization of novel proteins identified by
            large-scale cDNA sequencing
  JOURNAL   EMBO Rep. 1 (3), 287-292 (2000)
   PUBMED   11256614
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK302702.1, DC402111.1, AL136748.1 and AI829695.1.
            
            Summary: This gene product is a member of the FAM186 family,
            however, its exact function is not known. Alternatively spliced
            transcript variants have been found for this gene. [provided by
            RefSeq, Sep 2009].
            
            Transcript Variant: This variant (2) uses an alternate donor splice
            site in the first exon, and also contains an alternate 3' terminal
            exon, compared to variant 1. It is represented as non-coding
            because the use of the 5'-most supported translational start codon,
            as used in variant 1, renders the transcript a candidate for
            nonsense-mediated mRNA decay (NMD).
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-348               AK302702.1         1-348
            349-583             DC402111.1         340-574
            584-2864            AL136748.1         348-2628
            2865-3088           AK302702.1         2865-3088
            3089-3106           AI829695.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..3106
                     /organism="Homo sapiens"
                     /mol_type="transcribed RNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.12"
     gene            1..3106
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /note="family with sequence similarity 186, member B"
                     /db_xref="GeneID:84070"
                     /db_xref="HGNC:25296"
     misc_RNA        1..3106
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /product="family with sequence similarity 186, member B,
                     transcript variant 2"
                     /db_xref="GeneID:84070"
                     /db_xref="HGNC:25296"
     exon            1..426
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    151..324
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /inference="COORDINATES:
                     alignment:Blast2seq::RefSeq|NM_032130.2"
                     /note="primary ORF has stop codon >50 nucleotides from the
                     terminal splice site; nonsense-mediated decay (NMD)
                     candidate"
     exon            427..652
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /inference="alignment:Splign:1.39.8"
     exon            653..835
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /inference="alignment:Splign:1.39.8"
     exon            836..2501
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /inference="alignment:Splign:1.39.8"
     variation       1891
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:199944340"
     exon            2502..2694
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /inference="alignment:Splign:1.39.8"
     exon            2695..2864
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /inference="alignment:Splign:1.39.8"
     exon            2865..3099
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
                     /inference="alignment:Splign:1.39.8"
     polyA_site      3099
                     /gene="FAM186B"
                     /gene_synonym="C12orf25"
ORIGIN      

gtgtttggcagttaccagaggagctgtgcctgggcagagggtacccaggagacaccctggtgcccttaacctccaaagcaggcaacattgtgtgtccaggcctgtggaccagaaacacaggatgttttgtgactgacagagtgatccaaaatggagaaggatgaccccccacagttggtgactcccacatcagtgaaagccatcatcctgaggattgaggctgcccagctaactcgggctcaagaggtagcccctgagatgaaggaatcactcttacattgggatctgatgcggagactgggggctgatcccaggtttgagtgagattccagctctgggtcctcagaggccctgggatattcagcaacctgggtctgcagacagattagtataaattatctctctcctaaacttggcatatacagggatatttctacccagctctcagacattttggacaatgtcaattgtgtcatcaaccgcttccaggaagaattaggatatgatttaaaagaaaatgccaaatctcagcagagagatccaaagggcaagaagagattcatcttgctggaaaaaattgcctccttctccaaagatgctatgatgaaggagaagcacctgtatgacattctccgctggctgggtgactggggtgacactctgacctatgagattgggcccaggaagagtgaagaggaagcagcagctctggacgaatggattgaagtgacggagaaagtgttaccgctgtccctcattgccaccaaaagaggcatcgagtcactcactgccctttgctccactctcattgaaggacaaaagaaaaggtcacaagtgtccaaacgcaccttctggcagggctggcagggaagaagcccacagacatctccatcccatcctcagccactaagcccagaacagatgctccaggaccagcataccatgaacacgaaggcctcggaggtgacgtccatgctgcaggagctcctggactctaccatgttcagcaagggggaggtcagggccatcaggtacatggccactgtggtggagaacctcaacaaggccttgatcctccaacacaaggagaacaggagcctggagaccaaatacaggcacctgcaaatgcaggcgaccaaagagctcagcagccagaggctgcacttccagcagttcatggaggtccttgagagcaggagggatgctctgctgaagcaggtagagatcttagggggaaggtaccatgaccttctcctgatgaagcaggccttggagttccagctgaagaaggctcagaatgctacaggtcaggcagaagacctggctgaggtttctgttgactccccaggtccctctgagagagagaccctcccaaggaaagaaacagtcatggaggaaagccaacaggaaccgatgaaggaggagcagttgttctcgccacttcccccaagtcccatggccatgatacgggacagtggtgctatagctgcagggcaccagccactttccaccatgactgtgcgctcgagggtcgcagatgtgttcggcagcaaggacactgagagccttgagcctgtgcttttacccttagtagatcgcaggtttcctaagaaatgggaaagaccggtggcagaaagcttaggccacaaagacaaagaccaggaggactacttccagaagggaggactccaaattaagttccactgtagcaagcagctgtctctagagagctccaggcaggtgacctctgagagccaagaggagccctgggaggaggaattcggccgggagatgcggaggcagctgtggctggaggaggaggagatgtggcagcagcggcagaagaagtgggccctgctggagcaggagcatcaggagaagctgcggcagtggaatctggaagacctggccagggagcaacagcggagatgggtccagctagaaaaggagcaggagagcccacggagagagccagagcagctaggggaggatgtggagaggaggatcttcacacccaccagtcgatggagggacttggagaaggcagagctatcattagtgcctgccccaagccggacccaatctgctcaccaaagcaggaggccacacttgcccatgtctcctagtacccagcagcctgccctgggaaagcagagacctatgagttcagtggagtttacctacagaccacggacccgccgagttcccacaaagcccaagaaatctgcctcctttcctgtcactgggacatccatccgaaggctgacctggccctctttgcagatatcccctgcaaatattaagaagaaggtgtaccacatggacatggaggcccagaggaagaacctgcagctcctgagtgaggagtctgagttgaggctgccccactacctgcgcagcaaagcactggagctcaccaccaccaccatggagctgggcgcgctcaggctgcagtacctgtgccataagtacatcttctatagacgcctccagagcctccggcaagaagcgatcaaccatgtacaaatcatgaaagaaacggaggcttcctacaaggcccagaacctctacatcttcctggaaaacattgaccgcctgcagagtctcaggctgcaggcctggacggacaagcagaaggggctggaggagaagcaccgagagtgcctgagcagcatggtgaccatgttccccaagctccagctggagtggaacgttcacctgaacatccctgaggtcacctcgccaaagccaaagaaatgcaagttgcctgcagcctcaccccggcacatccgccccagtggccccacctacaagcagccctttctgtctaggcaccgggcatgtgtgcccctgcagatggcccggctcttggcactgtgcttaaggggcctggtggctgaacttgctctggtgatggaggactttgaccttctgcacgtcctctagcgagctctctggcaagcatgcagagtgtctgacattcttctcctgctttggtaacaatttcatcttcttaaaggcaaagaaagcctgcacgggccaagctgtgaagccaagagggttggaagacaaatatatatgtgtgtgtatctttgtgtaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:84070 -> Cellular component: GO:0043234 [protein complex] evidence: IDA