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2020-10-26 19:44:42, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_199462               7791 bp    mRNA    linear   PRI 15-JUN-2013
DEFINITION  Homo sapiens dual serine/threonine and tyrosine protein kinase
            (DSTYK), transcript variant 2, mRNA.
ACCESSION   NM_199462 XM_290898
VERSION     NM_199462.2  GI:218563734
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7791)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS ONE 7 (12), E51954 (2012)
   PUBMED   23251661
REFERENCE   2  (bases 1 to 7791)
  AUTHORS   Peng,J., Dong,W., Chen,Y., Mo,R., Cheng,J.F., Hui,C.C., Mohandas,N.
            and Huang,C.H.
  TITLE     Dusty protein kinases: primary structure, gene evolution, tissue
            specific expression and unique features of the catalytic domain
  JOURNAL   Biochim. Biophys. Acta 1759 (11-12), 562-572 (2006)
   PUBMED   17123648
  REMARK    GeneRIF: Confocal imaging of transiently expressed human Dusty-GFP
            fusion proteins showed a cytoplasmic distribution.
REFERENCE   3  (bases 1 to 7791)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   4  (bases 1 to 7791)
  AUTHORS   Zha,J., Zhou,Q., Xu,L.G., Chen,D., Li,L., Zhai,Z. and Shu,H.B.
  TITLE     RIP5 is a RIP-homologous inducer of cell death
  JOURNAL   Biochem. Biophys. Res. Commun. 319 (2), 298-303 (2004)
   PUBMED   15178406
REFERENCE   5  (bases 1 to 7791)
  AUTHORS   Robertson,N.G., Khetarpal,U., Gutierrez-Espeleta,G.A., Bieber,F.R.
            and Morton,C.C.
  TITLE     Isolation of novel and known genes from a human fetal cochlear cDNA
            library using subtractive hybridization and differential screening
  JOURNAL   Genomics 23 (1), 42-50 (1994)
   PUBMED   7829101
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC060870.1, BC053627.1,
            AC093422.3 and AY429674.1.
            On Dec 20, 2008 this sequence version replaced gi:40806180.
            
            Summary: This gene encodes a dual serine/threonine and tyrosine
            protein kinase which is expressed in multiple tissues. It is
            thought to function as a regulator of cell death. Multiple
            transcript variants encoding different isoforms have been found for
            this gene. [provided by RefSeq, Dec 2008].
            
            Transcript Variant: This variant (2) lacks an in-frame exon in the
            3' coding region, as compared to variant 1. The encoded isoform 2
            is missing an internal segment, as compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053627.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025098 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                BC060870.1         1-37
            38-1984             BC053627.1         1-1947
            1985-1985           AC093422.3         54347-54347         c
            1986-3404           BC053627.1         1949-3367
            3405-7791           AY429674.1         3512-7898
FEATURES             Location/Qualifiers
     source          1..7791
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q32.1"
     gene            1..7791
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /note="dual serine/threonine and tyrosine protein kinase"
                     /db_xref="GeneID:25778"
                     /db_xref="HGNC:29043"
                     /db_xref="HPRD:11495"
                     /db_xref="MIM:612666"
     exon            1..329
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     CDS             65..2719
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /EC_number="2.7.12.1"
                     /note="isoform 2 is encoded by transcript variant 2;
                     receptor interacting protein 5; receptor interacting
                     protein kinase 5; dusty protein kinase; sgK496; dusty PK;
                     sugen kinase 496; RIP-homologous kinase;
                     receptor-interacting serine/threonine-protein kinase 5"
                     /codon_start=1
                     /product="dual serine/threonine and tyrosine protein
                     kinase isoform 2"
                     /protein_id="NP_955749.1"
                     /db_xref="GI:40806181"
                     /db_xref="CCDS:CCDS1452.1"
                     /db_xref="GeneID:25778"
                     /db_xref="HGNC:29043"
                     /db_xref="HPRD:11495"
                     /db_xref="MIM:612666"
                     /translation="
MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHNHTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQDCNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAHQGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDLVNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESERSPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAKALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGARPERLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMNRLCKSNSEQPNRGLDDST
"
     misc_feature    2021..2620
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /note="Serine/Threonine protein kinases, catalytic domain;
                     Region: S_TKc; smart00220"
                     /db_xref="CDD:197582"
     misc_feature    2036..2620
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /note="Catalytic domain of Protein Kinases; Region: PKc;
                     cd00180"
                     /db_xref="CDD:173623"
     misc_feature    order(2036..2050,2060..2062,2099..2101,2105..2107,
                     2195..2197,2264..2275,2279..2281,2393..2395,2399..2401,
                     2405..2410,2414..2416,2447..2449,2456..2458,2495..2506)
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /note="active site"
                     /db_xref="CDD:173623"
     misc_feature    order(2036..2050,2060..2062,2099..2101,2105..2107,
                     2195..2197,2264..2275,2393..2395,2399..2401,2405..2410,
                     2414..2416,2447..2449)
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:173623"
     misc_feature    order(2048..2050,2279..2281,2393..2395,2399..2401,
                     2405..2407,2456..2458,2495..2506)
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173623"
     misc_feature    order(2444..2464,2495..2506)
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /note="activation loop (A-loop); other site"
                     /db_xref="CDD:173623"
     exon            330..718
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     exon            719..1388
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     STS             929..1016
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="SHGC-76207"
                     /db_xref="UniSTS:17625"
     STS             980..1063
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="STS-M62021"
                     /db_xref="UniSTS:26245"
     exon            1389..1621
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     exon            1622..1705
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     exon            1706..1882
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     exon            1883..2012
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     exon            2013..2169
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     variation       2092
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1062715"
     exon            2170..2302
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     exon            2303..2416
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     exon            2417..2531
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     exon            2532..7774
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /inference="alignment:Splign:1.39.8"
     STS             2764..2966
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="HSC26A082"
                     /db_xref="UniSTS:76608"
     variation       2770
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:11367"
     STS             2831..3006
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="SHGC-76213"
                     /db_xref="UniSTS:41049"
     polyA_site      3019
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
     STS             3198..3388
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="STS-N25749"
                     /db_xref="UniSTS:37728"
     STS             3245..3365
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="SHGC-76208"
                     /db_xref="UniSTS:74468"
     STS             3513..4645
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="D8S2279"
                     /db_xref="UniSTS:473907"
     STS             3513..3602
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="D8S2279"
                     /db_xref="UniSTS:473907"
     variation       4255
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1061132"
     variation       4306
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11240369"
     STS             4416..4537
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="SHGC-76193"
                     /db_xref="UniSTS:10283"
     STS             4611..4700
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="PMC156606P1"
                     /db_xref="UniSTS:271408"
     variation       4740
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:67700841"
     variation       5572
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3183297"
     STS             6676..6829
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="RH69217"
                     /db_xref="UniSTS:10312"
     STS             6773..6874
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="SHGC-76211"
                     /db_xref="UniSTS:70767"
     STS             6900..7086
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="D1S1361"
                     /db_xref="UniSTS:149557"
     STS             6900..7014
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="D10S16"
                     /db_xref="UniSTS:155756"
     STS             7616..7741
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /standard_name="SHGC-76209"
                     /db_xref="UniSTS:18928"
     variation       7619
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1046925"
     polyA_signal    7751..7756
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
     variation       7762
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7554368"
     polyA_site      7774
                     /gene="DSTYK"
                     /gene_synonym="DustyPK; HDCMD38P; RIP5; RIPK5"
ORIGIN      
ggggaggagggaggccgggcctgcggccggggaccgagccgcaaagacagagcgggcagaggcgatggagggcgacggggtgccatggggcagcgagcccgtctcgggtcccggccccggcggcggcggaatgatccgcgagctgtgccggggcttcggccgctaccgccgctacctgggacggctgcgacagaacctgcgcgagacccagaagttcttccgcgacatcaagtgctcccacaaccacacttgtctctcctccctcacgggcggcggcggggccgagcgcggccctgcaggcgatgtcgccgaaaccgggctgcaggcgggccaactgagctgcatttccttcccacctaaggaagagaagtacctccagcagattgtggactgcctcccttgcatactgatcctcggccaggattgtaacgtcaagtgccagctgttgaatctgctgttgggggtgcaggtgcttcccaccaccaagctgggcagtgaggagagctgtaagcttcggcgcctccgcttcacctatgggactcagactcgggtcagcctggcgctccctggacagtatgaactagtgcacacgctggttgctcatcagggcaactgggagaccatccctgaggaggatctggaggtccaagagaacaatgaggatgctgctcatgttttagcggaactggaggtaacgatgcaccatgctctcttacaggaagtggacgttgtggtagcaccatgccaaggcctccggcccacagtggatgttctgggtgacttggtgaatgatttcttgcctgtgataacctatgcactccacaaagatgaactctctgagagggatgagcaagagcttcaggaaatccgaaagtatttctcctttcctgtattctttttcaaagtgccgaaactgggctcggagataatagactcctcaaccaggagaatggagagcgaaagatcaccgctttatcgccagctaattgacctgggctatctgagcagcagtcactggaactgtggggctcctggccaggatactaaagctcagagcatgttggtggaacagagtgaaaagctgagacacttgagcacattttctcaccaggtgttacagactcgcctggtggatgcagccaaggccctgaacctggtgcactgccactgccttgacatctttattaaccaggcatttgacatgcagcgggacctgcagatcactcccaaacgtctggaatatactcgaaaaaaggagaatgagttgtatgaatcattgatgaatattgccaaccgaaagcaggaggaaatgaaggatatgattgttgagacacttaataccatgaaggaggaacttctggatgatgctactaacatggagtttaaagacgtcattgtccctgagaatggagaaccagtaggcaccagagagatcaaatgctgcatccgacagatccaggaactcatcatctcccgacttaatcaggcagtggctaataagctgatcagctcagtggattacctgagggaaagcttcgtcggaaccctggaacgatgtctgcagagcctggagaagtctcaggatgtctcagttcacatcaccagtaattatctcaaacagatcttaaatgctgcctatcatgttgaagtcacgtttcactcagggtcgtcagttacaaggatgctatgggagcaaatcaaacagatcatccagcgcatcacatgggtgagcccacctgccatcactctggaatggaagaggaaggtggcccaggaagccattgagagcctcagcgcctccaaattggctaagagcatttgcagccaattccggactcggctcaatagttcccacgaggcttttgcagcctccttgcggcagctggaagctggccactcaggccggttagagaaaacggaagatctatggctgagggttcggaaagatcatgctccccgcctggcccgcctttctctggaaagctgttctttacaggatgtcttgcttcatcgtaaacctaaactgggacaggaactgggccggggccagtatggtgtggtatacctgtgtgacaactggggaggacacttcccttgtgccctcaaatcagttgtccctccagatgagaagcactggaatgatctggctttggaatttcactatatgaggtctctgccgaagcatgagcgattggtggatctccatggttcagtcattgactacaactatggtggtggctccagcattgctgtgctcctcattatggagcggctacaccgggatctctacacagggctgaaggctgggctgaccctggagacacgtttgcagatagcactagatgtggtggagggaatccgcttcctgcacagccagggacttgtccatcgtgatatcaaactgaaaaatgtgctgctggataagcagaaccgtgccaagatcactgacttaggattctgcaagccagaggccatgatgtcaggcagcattgtggggacaccaatccatatggcccctgaacttttcacaggggctcgcccagaacgtcttcctgtgtttgatgaggagtgctggcagttgatggaagcctgttgggatggcgaccccttgaagaggcctctcttgggcattgtccagcccatgctccagggcatcatgaatcggctctgcaagtccaattctgagcagccaaacagaggactagatgattctacttgaaagcaaagacctttctctttcactctctagttatttccttccccctcaccttttggccatggggagaatttgacatttattcactataggacacactcccaagggaactggtgcttgctgggaaacttggaaccttcccaggcagggatgactcctggacagtgaagagttgaatgactgagcatattcagcagctcactgaagcgccaagctatccctttagcaaaaaagtgtctcagatgtgtaaaagctgaggaatgtggtgttctggcttcacaaatgaaaaggaggcagatgttaccattgtcttttcactgtatatacttctaagacagcaagcgggacactgcagtggcaatagtgttaaaaaatctcattctcatgatttttggctctagctaggaatagtttagtcaggactcagaaaatttgagcttagttctgggattatgaaaacatggggacaaaaacaataacttgtggatgtctggttcctgctgtctgcagccaggtatctcaggttgcaatggtcagaagtcccagtgagggagctagaaacagagctatctgttcctcatagtgccagtgtgtttacatttataggaccacatatccctggtttctgggggagggtttcactgttacatcaccaagaggccctgaaaagaggaaaaaaaaaaaaaaagaggccaggcatggtggctcacgcctgtaatctcagcactttgggaggctgaggcgggcggatcacaaggtccagagttcaagagcagcctggccaacatggtgaaaccccgtctctactaaagatacaaaaaattagccgggcgtggtggtgcatgcctgtaatccaagatactcaggaggctgaggcaggagaatcgcttgaacctgggaggcggaggttgcagtgagccgagatcatgccattgcactccagcctgggcgacagagtgagactctgtctcaaaaaaaaaaaaaaaatagaatgtgtatgcatatatttgtgtgtatatgtatatatgtgtgtgtgtctatatctctatctatatagacatacacacaggagttattggatttagagttactgctaaccccagaacagaatctgttcttttacctttgagtcttttcttttgtttacctcttttcatctcaaagtgggaaagctccagataacatggtacttaggagtgagtgtctaagcaaaaccaacccaatgcgaagtatttgggtgagaactgagaggtgggagatgattggaggccatggcctatgtacaaacatactggaagaaaaccagcttgtttttaaaacttaacacaatcagaaatttttctttttgtgtttgaatctaacacactgacgtttggaaaacttgatcaatgagcttttaaccacgatttctcccgcaatttgttccttctttttacctttttaaaaatctgttagaagaaaaaaagcagcagacgaaagagaaaaaccctcctctggtagttctgtgtgtgcccctcacccctgtgtgctagtgtctgggaagtttccctgaaaggtgggaggcgggtgggtggtcttttggagggttcctcatgaagtgtgcttgaggaaagaaattctgattctaggcagaggaaggggaacaatttaaatattggtgcatctcagatgcacttgacttcaagccttcctcaaccaaactggtccattagattccgaaaaacaggtagacgaggaagtagacagtggaagtgagtagtctccctccatctgcctaatccccaataactgtggtctggcccctgtgttcagcccgagagtttgtaaaacaggtccccaggtaggtgtataagatgagttgcaaattagccgggcatgctggcacgcaccagtaatcccagctacttgggaggctgaggcaggagaatcacttgaacccgggaggcagaggtcatggtgagccgagatcacgccactgcactccagcctgggcaacagagcgagactctatctcaaaaaaaaacaaaaaaaaaaacaaaaaacaaagatgagtcgcacatctgctgctgggattttctagggttgtctatgacagaatgaccatcttttaaatattaatggagtataaatggagtctataatgggtctttcatataacttttaactctttggctatcctgggctctgatcatgatatgtttgagcatagtagctccctaaactcttggagcctttcagaaattccatgtagtgctaataacctttttacttgcaaatgataaagtaactgactcagtgtctttgggctctgcaggctttagccttgttttggtaggatgttcagtatattctcagaatttttaccacctatttagctatacttcaagtactctattctctgcactaacttactgtccttctgggaactatgatggggcttcaagggagtcaggtgtcaagaaaggaggggtaagtactctctacttgctggaaaatcattgtaagtctgttgtgtatgaaattttaggaaaagtcttatatagttccctttccagactgttttcttttgactctaactataatcataagtctgtgcttccattatgaaggtcacattcctagcattcttgggaagtattagctcatactctcattcacatatgggaggttagatttttttcctctacccagagtccctttttagtttaccccacggcttagtttgctgtcagataccagttctctagcagattccccaacagttttttccccagtggggagggtggaagggagggactgatataagtaaggagatgagtagttgtgttacagttcattttctttaaaaaaaagtattttgagaaaaggtgcaaaatattcttgaaagtctctaggccagccaaagtccacatatggatatttggggatgttatttaaatactcagcaggctgagtgcaggtatacgtgtgtatagagtgtgtatactttgcttttgttttataacattgtcagctaattttggctttgttctttggcatccattcttattataagtgatggaatgccatgaaatgtactgtattgtatattacttgggaggacactaggttttcaaagaagtctggcagcacttgggttatagagggctcagcatgaccaaagtcctaaagattttacctcccagctttggttgtatgtgttcccaagtggtgaggtgagattgtggctggaggaagaaaaaggatggcatgaaagaatgacccttattgtggtctgtccttctaatcaacataattagggcagcttaccccaacatgaaaatgatgacctggccatttttaatggccagagcttgaagtctggtctctcattttgtttcagaaatgagtgagaggccttcctgcagagcagtcaggagaaatggtggagcctggggccctggaatggctgaccctgtgcctagagagctgatggcaagggctgtctggcatggctcatttgggtggggtttccccaggcataccttagttccctgatcctctgcaaagagtagctcattgactgagcaagcgcttcaggaggactgtgctggttgttcccagaccaaagagagtcacttttgactccatcaacttcaaggggacagagcctaggcagcagattctcctaatttttaacactaaaattcaaggaagcagtggaggaaagaatgcattactaccacagatagaaataggggactcatagaactctcgactagtacctgtcagctctcaaatgcattcttgtgtctttgcttgagctgccaaagaagggtcacaaagtgttcttcctcatggaagaagtgcctcggggttgcagggctgcaaagtgacaactgcactgaatgacactttattttttggctttggcttattatttagcactgggaggcccaggggaattggtgattacagtagcactttgggaagttaaagccccctttgggcttgctttggagagatgatggcatgcttggtattccatttggataatcaggaagcctccctagtccatccatattgtgtcagagtgggattaacaaccctggaagagtccactgccaaaagagtagttgctttcctggaatttccaaagcttttggattttctggatcaagtaacccactttttaaaacctgaggtcaggagttcgagaccagcctggtaacatggtgaaaccccgtctctattaaaaatagaaaaaattagccaggcatggtggcgggcacctatagtcccagctactcaggaggctgaggtaggagaattgcttgaacccaggagacagaggctgcattgagccaagatcacaccactgcactccagcctgggcagcagagcaagactccatctcaaaaaaaaaaaaaagaaaaagaaaaagaaggttaatccttcagttatggaggtgggatgaatagagcttgtttgatgttaaagtgggtaaggagggagtggccttgagacacttgtattccaaactctcctggaggtttccagtagcactactgttcctaaaagggtttcatttttaacttcatctgttttgttaacatccagtccaattgaggtgatctcagaggtgcatcaggacatctagcactggggaggccaccttgcccagatagttgaaaagaaaattggtctgggcagcctgttgtcttttgtcttcatgtaatgttttttctttgttttaaaggactaatgtttattacagtgttaaataaaagtgtaagatactaagtgtgtagaataaaagtgcaataacaaaagacaatgactttggcacacacttcagtctttatcctctctcctttcttgtgctacctggctctttccataatattgttacagcaggaccgtcttaattgtgtgcattttgaagagatgcgactctgggttaatcttcattagtgtaatattgaagggttgggtttggttttatagagtattctgtatacttgttgggatacacaaataccagatgtgctgtataataaagatcacattaacgttttaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:25778 -> Molecular function: GO:0004674 [protein serine/threonine kinase activity] evidence: IEA
            GeneID:25778 -> Molecular function: GO:0004712 [protein serine/threonine/tyrosine kinase activity] evidence: IEA
            GeneID:25778 -> Molecular function: GO:0004713 [protein tyrosine kinase activity] evidence: IEA
            GeneID:25778 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
            GeneID:25778 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:25778 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:25778 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA
            GeneID:25778 -> Cellular component: GO:0045111 [intermediate filament cytoskeleton] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_955749 -> EC 2.7.12.1

by @meso_cacase at DBCLS
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