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2020-10-24 07:07:37, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_198976               2320 bp    mRNA    linear   PRI 01-MAY-2013
DEFINITION  Homo sapiens negative elongation factor complex member C/D
            (NELFCD), mRNA.
ACCESSION   NM_198976
VERSION     NM_198976.2  GI:399788585
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2320)
  AUTHORS   Wu,W., Sun,Z., Wu,J., Peng,X., Gan,H., Zhang,C., Ji,L., Xie,J.,
            Zhu,H., Ren,S., Gu,J. and Zhang,S.
  TITLE     Trihydrophobin 1 phosphorylation by c-Src regulates MAPK/ERK
            signaling and cell migration
  JOURNAL   PLoS ONE 7 (1), E29920 (2012)
   PUBMED   22238675
  REMARK    GeneRIF: Trihydrophobin 1 phosphorylation by c-Src regulates
            MAPK/ERK signaling and cell migration.
REFERENCE   2  (bases 1 to 2320)
  AUTHORS   Zou,W., Yang,Y., Wu,Y., Sun,L., Chi,Y., Wu,W., Yun,X., Xie,J. and
            Gu,J.
  TITLE     Negative role of trihydrophobin 1 in breast cancer growth and
            migration
  JOURNAL   Cancer Sci. 101 (10), 2156-2162 (2010)
   PUBMED   20735431
  REMARK    GeneRIF: TH1 might play an important role in regulation of
            proliferation and invasion in human breast cancer.
REFERENCE   3  (bases 1 to 2320)
  AUTHORS   Yang,Y., Zou,W., Kong,X., Wang,H., Zong,H., Jiang,J., Wang,Y.,
            Hong,Y., Chi,Y., Xie,J. and Gu,J.
  TITLE     Trihydrophobin 1 attenuates androgen signal transduction through
            promoting androgen receptor degradation
  JOURNAL   J. Cell. Biochem. 109 (5), 1013-1024 (2010)
   PUBMED   20069563
  REMARK    GeneRIF: These results indicate that TH1 is a novel regulator to
            control the duration and magnitude of androgen signal transduction
            and might be directly involved in androgen-related developmental,
            physiological, and pathological processes.
REFERENCE   4  (bases 1 to 2320)
  AUTHORS   Sun,J. and Li,R.
  TITLE     Human negative elongation factor activates transcription and
            regulates alternative transcription initiation
  JOURNAL   J. Biol. Chem. 285 (9), 6443-6452 (2010)
   PUBMED   20028984
  REMARK    GeneRIF: diverse transcriptional consequence of NELF-mediated
            RNAPII pausing in the human genome
REFERENCE   5  (bases 1 to 2320)
  AUTHORS   Pal,P., Mihanovic,M., Molnar,S., Xi,H., Sun,G., Guha,S., Jeran,N.,
            Tomljenovic,A., Malnar,A., Missoni,S., Deka,R. and Rudan,P.
  TITLE     Association of tagging single nucleotide polymorphisms on 8
            candidate genes in dopaminergic pathway with schizophrenia in
            Croatian population
  JOURNAL   Croat. Med. J. 50 (4), 361-369 (2009)
   PUBMED   19673036
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   6  (bases 1 to 2320)
  AUTHORS   Yin,X.L., Chen,S. and Gu,J.X.
  TITLE     Identification of TH1 as an interaction partner of A-Raf kinase
  JOURNAL   Mol. Cell. Biochem. 231 (1-2), 69-74 (2002)
   PUBMED   11952167
  REMARK    GeneRIF: In a two-hybrid screen of human fetal liver cDNA library,
            TH1 was detected as a new interaction partner of A-Raf; this
            specific interaction may have played a critical role in the
            activation of A-Raf.
REFERENCE   7  (bases 1 to 2320)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
REFERENCE   8  (bases 1 to 2320)
  AUTHORS   Ping,Y.H. and Rana,T.M.
  TITLE     DSIF and NELF interact with RNA polymerase II elongation complex
            and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA
            polymerase II and DSIF during transcription elongation
  JOURNAL   J. Biol. Chem. 276 (16), 12951-12958 (2001)
   PUBMED   11112772
REFERENCE   9  (bases 1 to 2320)
  AUTHORS   Bonthron,D.T., Hayward,B.E., Moran,V. and Strain,L.
  TITLE     Characterization of TH1 and CTSZ, two non-imprinted genes
            downstream of GNAS1 in chromosome 20q13
  JOURNAL   Hum. Genet. 107 (2), 165-175 (2000)
   PUBMED   11030415
REFERENCE   10 (bases 1 to 2320)
  AUTHORS   Yamaguchi,Y., Takagi,T., Wada,T., Yano,K., Furuya,A., Sugimoto,S.,
            Hasegawa,J. and Handa,H.
  TITLE     NELF, a multisubunit complex containing RD, cooperates with DSIF to
            repress RNA polymerase II elongation
  JOURNAL   Cell 97 (1), 41-51 (1999)
   PUBMED   10199401
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from HY015074.1, AK293410.1 and
            BQ022435.1.
            On Aug 8, 2012 this sequence version replaced gi:39812491.
            
            Summary: The NELF complex of proteins interacts with the DSIF
            protein complex to repress transcriptional elongation by RNA
            polymerase II. The protein encoded by this gene is an essential
            part of the NELF complex. Alternative translation initiation site
            usage results in the formation of two isoforms with different
            N-termini. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC014952.1, AJ238379.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                HY015074.1         2-49
            49-2179             AK293410.1         1-2131
            2180-2320           BQ022435.1         1-141               c
FEATURES             Location/Qualifiers
     source          1..2320
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q13"
     gene            1..2320
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /note="negative elongation factor complex member C/D"
                     /db_xref="GeneID:51497"
                     /db_xref="HGNC:15934"
                     /db_xref="MIM:605297"
     exon            1..162
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       33
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151333"
     CDS             49..1848
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /note="TH1 drosophila homolog; trihydrophobin 1; negative
                     elongation factor proteins C and D; NELF-C/D; TH1-like
                     protein"
                     /codon_start=1
                     /product="negative elongation factor C/D"
                     /protein_id="NP_945327.2"
                     /db_xref="GI:399788586"
                     /db_xref="CCDS:CCDS13473.2"
                     /db_xref="GeneID:51497"
                     /db_xref="HGNC:15934"
                     /db_xref="MIM:605297"
                     /translation="
MRRARSREGMAGAVPGAIMDEDYYGSAAEWGDEADGGQQEDDSGEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLSENYTAVAQTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVFSRVLRTSLATILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRIAQEVQRFAQEKGHDASQITLALGTAASYPRACQALGAMLSKGALNPADITVLFKMFTSMDPPPVELIRVPAFLDLFMQSLFKPGARINQDHKHKYIHILAYAASVVETWKKNKRVSINKDELKSTSKAVETVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIKTEGEHDPVTEFIAHCKSNFIMVN
"
     misc_feature    202..1842
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /note="TH1 protein; Region: TH1; pfam04858"
                     /db_xref="CDD:147160"
     misc_feature    103..105
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /note="translation initiation codon of NELF-D isoform"
     variation       141
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375172251"
     exon            163..278
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       168
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200051352"
     variation       207
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376187583"
     variation       217
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143738831"
     variation       229
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:199938188"
     variation       236
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144656284"
     variation       250..251
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:34679405"
     exon            279..388
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     exon            389..498
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       396
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148513771"
     variation       485
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:202039877"
     exon            499..606
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       507
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139317340"
     variation       516
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142656445"
     variation       524
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201652404"
     variation       526
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74557096"
     variation       562
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367744594"
     variation       566
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371908338"
     variation       600
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2273360"
     exon            607..759
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       618
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142304902"
     variation       631
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368738630"
     variation       657
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371873766"
     variation       678
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375217590"
     variation       696
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369321955"
     variation       759
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17851253"
     exon            760..890
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       778
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368991410"
     variation       839
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373372450"
     variation       875
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147835273"
     exon            891..1056
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       899
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199670127"
     variation       900
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147821977"
     variation       916
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375256983"
     variation       949
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:61750762"
     variation       975
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368073324"
     variation       990
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148866352"
     variation       1008
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200745856"
     variation       1009
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375888011"
     variation       1026
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368566687"
     variation       1047
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372830513"
     variation       1052
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:375994512"
     exon            1057..1191
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       1060
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:150325198"
     variation       1062
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:59729619"
     variation       1070
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140786664"
     variation       1080
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377766658"
     variation       1086
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:137872664"
     variation       1104
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35963878"
     variation       1123
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143044496"
     variation       1157
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200667528"
     variation       1158
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369337569"
     variation       1161
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148160603"
     variation       1162
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372815228"
     variation       1170
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143108259"
     exon            1192..1331
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       1200
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:41276960"
     variation       1202
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188525919"
     variation       1245
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138968784"
     variation       1272
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372620907"
     exon            1332..1446
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     STS             1337..1499
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /standard_name="TH1L"
                     /db_xref="UniSTS:505928"
     variation       1380
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368381606"
     variation       1392
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189567482"
     variation       1401
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200807638"
     variation       1427
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:193192"
     variation       1433
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371084351"
     variation       1434
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141996345"
     exon            1447..1542
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       1450
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150855329"
     variation       1468
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:6123843"
     variation       1473
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:139324271"
     variation       1478
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149977485"
     variation       1506
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144257648"
     variation       1530
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372330781"
     variation       1533
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376830862"
     exon            1543..1683
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       1549
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373208083"
     variation       1584
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374913633"
     variation       1615
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140598361"
     variation       1642
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369278623"
     variation       1646
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:144525220"
     variation       1668
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200887618"
     variation       1677
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141353754"
     exon            1684..1813
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       1684
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370660207"
     variation       1692
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113105477"
     variation       1705
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367687877"
     variation       1722
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371935126"
     variation       1727
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142546785"
     variation       1728
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368757097"
     variation       1761
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150954057"
     variation       1767
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:188308685"
     variation       1779
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113490649"
     variation       1786
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150087382"
     exon            1814..2305
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /inference="alignment:Splign:1.39.8"
     variation       1834
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374163096"
     variation       1837
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138548641"
     variation       1862
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201888062"
     variation       1892
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368311400"
     variation       1893
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372607429"
     variation       1903
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:71754390"
     variation       1933
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:7341"
     variation       1977
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1043219"
     variation       1998
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182559465"
     variation       2002
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11542235"
     STS             2024..2261
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /standard_name="A004R34"
                     /db_xref="UniSTS:40603"
     variation       2027
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371727543"
     variation       2050
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184888819"
     variation       2055
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3182973"
     variation       2077
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:71743473"
     variation       2099
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189775868"
     variation       2127
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:111278153"
     STS             2165..2292
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /standard_name="SHGC-31778"
                     /db_xref="UniSTS:47319"
     variation       2205
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:375356368"
     polyA_site      2285
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
     polyA_site      2305
                     /gene="NELFCD"
                     /gene_synonym="HSPC130; NELF-C; NELF-D; TH1; TH1L"
ORIGIN      
gaggcgcgcggccgcgcgtgcgcccgcccgcccgtccccgcctcgcgcatgcgccgcgctcgctcgcgggagggcatggcgggggccgtgccgggcgccatcatggacgaggactactacgggagcgcggccgagtggggcgacgaggctgacggcggccagcaggaggatgattctggagaaggagaggatgatgcggaggttcagcaagaatgcctgcataaattttccacccgggattatatcatggaaccctccatcttcaacactctgaagaggtattttcaggcaggagggtctccagagaatgttatccagctcttatctgaaaactacaccgctgtggcccagactgtgaacctgctggccgagtggctcattcagacaggtgttgagccagtgcaggttcaggaaactgtggaaaatcacttgaagagtttgctgatcaaacattttgacccccgcaaagcagattctatttttactgaagaaggagagaccccagcgtggctggaacagatgattgcacataccacgtggcgggaccttttttataaactggctgaagcccatccagactgtttgatgctgaacttcaccgttaagcttatttctgacgcagggtaccagggggagatcaccagtgtgtccacagcatgccagcagctagaagtgttctcgagagtgctccggacctctctagctacaattttagatggaggagaagaaaaccttgaaaaaaatctccctgagtttgccaagatggtgtgccacggggagcacacgtacctgtttgcccaggccatgatgtccgtgctggcccaggaggagcaggggggctccgctgtgcgcaggatcgcccaggaagtgcagcgctttgcccaggagaaaggtcatgacgccagtcagatcacactagccttgggcacagctgcctcctaccccagggcctgccaggctctcggggccatgctgtccaaaggagccctgaaccctgctgacatcaccgtcctgttcaagatgttcacaagcatggaccctcctccggttgaacttatccgcgttccagccttcctggacctgttcatgcagtcactctttaaaccaggggctcggatcaaccaggaccacaagcacaaatacatccacatcttggcgtacgcagcaagcgtggttgagacctggaagaagaacaagcgagtgagcatcaataaagatgagctgaagtcaacgtcaaaagctgtcgaaaccgttcacaatttgtgttgcaacgagaacaaaggggcctctgaactagtggcagaattgagcacactttatcagtgtattaggtttccagtggtagcaatgggtgtgctgaagtgggtggattggactgtatcagaaccaaggtactttcagctgcagactgaccatacccctgtccacctggcgttgctggatgagatcagcacctgccaccagctcctgcacccccaggtcctgcagctgcttgttaagctttttgagactgagcactcccagctggacgtgatggagcagcttgagttgaagaagacactgctggacaggatggttcacctgctgagtcgaggttatgtacttcctgttgtcagttacatccgaaagtgtctggagaagctggacactgacatttcactcattcgctattttgtcactgaggtgctggacgtcattgctcctccttatacctctgacttcgtgcaacttttcctccccatcctggagaatgacagcatcgcaggtaccatcaaaacggaaggcgagcatgaccctgtgacggagtttatagctcactgcaaatctaacttcatcatggtgaactaatttagagcatcctccagagctgaagcagaacattccagaacccgttgtggaaaaaccctttcaagaagctgttttaagaggctcgggcagcgtcttgaaaatgggcaccgctgggaggaggtggatgacttctttacaaaggaaaatggtagcagcttcagtgagaaactgcccttacaaacagtcccttctctgctgtcaatccaatactgctcccaaatcctgttttcagtgttcatttccctcaaggcaggcgctgggctcccacgacccctcaggacagatctggccgtcagccgcgggccgctgggaactccactcggggaactcctttccaagctgacctcagttttctcacaagaacccagttagctgatgttttattgtaattgtcttaatttgctaagaacaagtaataagtaaatttttaaaaagcctttctgctgggttggattaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:51497 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:51497 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: TAS
            GeneID:51497 -> Biological process: GO:0006368 [transcription elongation from RNA polymerase II promoter] evidence: TAS
            GeneID:51497 -> Biological process: GO:0010467 [gene expression] evidence: TAS
            GeneID:51497 -> Biological process: GO:0016032 [viral process] evidence: TAS
            GeneID:51497 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IEA
            GeneID:51497 -> Biological process: GO:0050434 [positive regulation of viral transcription] evidence: TAS
            GeneID:51497 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
            GeneID:51497 -> Cellular component: GO:0032021 [NELF complex] evidence: IDA

by @meso_cacase at DBCLS
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