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2024-03-29 09:26:29, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_182734               7221 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens phospholipase C, beta 1 (phosphoinositide-specific)
            (PLCB1), transcript variant 2, mRNA.
ACCESSION   NM_182734
VERSION     NM_182734.2  GI:459215048
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7221)
  AUTHORS   Liu,M., Ingle,J.N., Fridley,B.L., Buzdar,A.U., Robson,M.E.,
            Kubo,M., Wang,L., Batzler,A., Jenkins,G.D., Pietrzak,T.L.,
            Carlson,E.E., Goetz,M.P., Northfelt,D.W., Perez,E.A.,
            Williard,C.V., Schaid,D.J., Nakamura,Y. and Weinshilboum,R.M.
  TITLE     TSPYL5 SNPs: association with plasma estradiol concentrations and
            aromatase expression
  JOURNAL   Mol. Endocrinol. 27 (4), 657-670 (2013)
   PUBMED   23518928
REFERENCE   2  (bases 1 to 7221)
  AUTHORS   Jia WH, Zhang B, Matsuo K, Shin A, Xiang YB, Jee SH, Kim DH, Ren Z,
            Cai Q, Long J, Shi J, Wen W, Yang G, Delahanty RJ, Ji BT, Pan ZZ,
            Matsuda F, Gao YT, Oh JH, Ahn YO, Park EJ, Li HL, Park JW, Jo J,
            Jeong JY, Hosono S, Casey G, Peters U, Shu XO, Zeng YX and Zheng W.
  CONSRTM   Colon Cancer Family Registry (CCFR); Genetics and Epidemiology of
            Colorectal Cancer Consortium (GECCO)
  TITLE     Genome-wide association analyses in East Asians identify new
            susceptibility loci for colorectal cancer
  JOURNAL   Nat. Genet. 45 (2), 191-196 (2013)
   PUBMED   23263487
REFERENCE   3  (bases 1 to 7221)
  AUTHORS   Adjobo-Hermans,M.J., Crosby,K.C., Putyrski,M., Bhageloe,A., van
            Weeren,L., Schultz,C., Goedhart,J. and Gadella,T.W. Jr.
  TITLE     PLCbeta isoforms differ in their subcellular location and their
            CT-domain dependent interaction with Galphaq
  JOURNAL   Cell. Signal. 25 (1), 255-263 (2013)
   PUBMED   23006664
  REMARK    GeneRIF: PLCbeta1 is enriched at the plasma membrane.
REFERENCE   4  (bases 1 to 7221)
  AUTHORS   Philip,F., Guo,Y., Aisiku,O. and Scarlata,S.
  TITLE     Phospholipase Cbeta1 is linked to RNA interference of specific
            genes through translin-associated factor X
  JOURNAL   FASEB J. 26 (12), 4903-4913 (2012)
   PUBMED   22889834
  REMARK    GeneRIF: Data show a novel role of phospholipase Cbeta1 (PLCbeta1)
            in gene regulation through translin-associated factor X (TRAX)
            association.
REFERENCE   5  (bases 1 to 7221)
  AUTHORS   Poduri,A., Chopra,S.S., Neilan,E.G., Elhosary,P.C., Kurian,M.A.,
            Meyer,E., Barry,B.J., Khwaja,O.S., Salih,M.A., Stodberg,T.,
            Scheffer,I.E., Maher,E.R., Sahin,M., Wu,B.L., Berry,G.T.,
            Walsh,C.A., Picker,J. and Kothare,S.V.
  TITLE     Homozygous PLCB1 deletion associated with malignant migrating
            partial seizures in infancy
  JOURNAL   Epilepsia 53 (8), E146-E150 (2012)
   PUBMED   22690784
  REMARK    GeneRIF: case report - homozygous deletion associated with
            malignant migrating partial seizures in infancy
REFERENCE   6  (bases 1 to 7221)
  AUTHORS   Hwang,S.C., Park,K.H., Ha,M.J., Noh,I.S., Park,T.B. and Lee,Y.H.
  TITLE     Distribution of phospholipase C isozymes in normal human lung
            tissue and their immunohistochemical localization
  JOURNAL   J. Korean Med. Sci. 11 (4), 305-313 (1996)
   PUBMED   8878798
REFERENCE   7  (bases 1 to 7221)
  AUTHORS   Zini,N., Sabatelli,P., Faenza,I., Ognibene,A. and Maraldi,N.M.
  TITLE     Interleukin-1 alpha induces variations of the intranuclear amount
            of phosphatidylinositol 4,5-bisphosphate and phospholipase C beta 1
            in human osteosarcoma Saos-2 cells
  JOURNAL   Histochem. J. 28 (7), 495-504 (1996)
   PUBMED   8872139
REFERENCE   8  (bases 1 to 7221)
  AUTHORS   Zauli,G., Previati,M., Caramelli,E., Bassini,A., Falcieri,E.,
            Gibellini,D., Bertolaso,L., Bosco,D., Robuffo,I. and Capitani,S.
  TITLE     Exogenous human immunodeficiency virus type-1 Tat protein
            selectively stimulates a phosphatidylinositol-specific
            phospholipase C nuclear pathway in the Jurkat T cell line
  JOURNAL   Eur. J. Immunol. 25 (9), 2695-2700 (1995)
   PUBMED   7589147
REFERENCE   9  (bases 1 to 7221)
  AUTHORS   Berstein,G., Blank,J.L., Jhon,D.Y., Exton,J.H., Rhee,S.G. and
            Ross,E.M.
  TITLE     Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11,
            its physiologic regulator
  JOURNAL   Cell 70 (3), 411-418 (1992)
   PUBMED   1322796
REFERENCE   10 (bases 1 to 7221)
  AUTHORS   Banno,Y., Yada,Y. and Nozawa,Y.
  TITLE     Purification and characterization of membrane-bound phospholipase C
            specific for phosphoinositides from human platelets
  JOURNAL   J. Biol. Chem. 263 (23), 11459-11465 (1988)
   PUBMED   2841328
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AB011153.3, AJ278314.1,
            AL049593.10 and BQ184058.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Mar 5, 2013 this sequence version replaced gi:33356543.
            
            Summary: The protein encoded by this gene catalyzes the formation
            of inositol 1,4,5-trisphosphate and diacylglycerol from
            phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium
            as a cofactor and plays an important role in the intracellular
            transduction of many extracellular signals. This gene is activated
            by two G-protein alpha subunits, alpha-q and alpha-11. Two
            transcript variants encoding different isoforms have been found for
            this gene. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (2) includes an alternate exon in
            the 3' end compared to variant 1. This exon contains an in-frame
            stop codon, and the resulting isoform (b) is shorter and has a
            distinct C-terminus compared to isoform a.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ278314.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025082, ERS025084 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3374              AB011153.3         1-3374
            3375-4165           AJ278314.1         2991-3781
            4166-5836           AB011153.3         4048-5718
            5837-5837           AL049593.10        36391-36391
            5838-6666           AB011153.3         5720-6548
            6667-7221           BQ184058.1         1-555               c
FEATURES             Location/Qualifiers
     source          1..7221
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20p12"
     gene            1..7221
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="phospholipase C, beta 1
                     (phosphoinositide-specific)"
                     /db_xref="GeneID:23236"
                     /db_xref="HGNC:15917"
                     /db_xref="MIM:607120"
     exon            1..486
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       218
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:139962835"
     variation       356
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372298655"
     variation       368
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374950042"
     misc_feature    379..381
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="upstream in-frame stop codon"
     CDS             388..3909
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /EC_number="3.1.4.11"
                     /note="isoform b is encoded by transcript variant 2;
                     PLC-beta-1; triphosphoinositide phosphodiesterase;
                     phosphoinositidase C; monophosphatidylinositol
                     phosphodiesterase;
                     1-phosphatidyl-D-myo-inositol-4,5-bisphosphate;
                     inositoltrisphosphohydrolase; phospholipase C-I;
                     1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
                     beta-1"
                     /codon_start=1
                     /product="1-phosphatidylinositol 4,5-bisphosphate
                     phosphodiesterase beta-1 isoform b"
                     /protein_id="NP_877398.1"
                     /db_xref="GI:33356544"
                     /db_xref="CCDS:CCDS13103.1"
                     /db_xref="GeneID:23236"
                     /db_xref="HGNC:15917"
                     /db_xref="MIM:607120"
                     /translation="
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKGEGSSSFLSETCHEDPSVSPNFTPPNPQALKW
"
     misc_feature    436..798
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="Phospholipase C (PLC) pleckstrin homology (PH)
                     domain; Region: PH_PLC; cd01248"
                     /db_xref="CDD:176324"
     misc_feature    order(457..480,502..522,538..558,571..585,598..612,
                     691..711,733..750,763..798)
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="core domain; other site"
                     /db_xref="CDD:176324"
     misc_feature    order(475..477,496..498,508..510,556..558)
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="inositol phosphate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176324"
     misc_feature    1057..1332
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="Phosphoinositide-specific phospholipase C,
                     efhand-like; Region: efhand_like; pfam09279"
                     /db_xref="CDD:150071"
     misc_feature    1333..>1779
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="Catalytic domain of metazoan
                     phosphoinositide-specific phospholipase C-beta; Region:
                     PI-PLCc_beta; cd08591"
                     /db_xref="CDD:176533"
     misc_feature    order(1378..1383,1468..1470,1474..1476,1519..1521,
                     1621..1623)
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="putative active site [active]"
                     /db_xref="CDD:176533"
     misc_feature    order(1378..1380,1519..1521)
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="catalytic site [active]"
                     /db_xref="CDD:176533"
     misc_feature    order(1381..1383,1468..1470,1474..1476,1621..1623)
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="Ca binding site [ion binding]; other site"
                     /db_xref="CDD:176533"
     misc_feature    <2005..2316
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="Catalytic domain of phosphoinositide-specific
                     phospholipase C-like phosphodiesterases superfamily;
                     Region: PI-PLCc_GDPD_SF; cl14615"
                     /db_xref="CDD:213131"
     misc_feature    2416..2775
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="C2 domain present in Phosphoinositide-specific
                     phospholipases C (PLC); Region: C2_PLC_like; cd00275"
                     /db_xref="CDD:175974"
     misc_feature    order(2467..2469,2545..2547,2638..2640,2644..2646,
                     2650..2652,2656..2658)
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="Ca2+ binding pocket [ion binding]; other site"
                     /db_xref="CDD:175974"
     misc_feature    3046..3048
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:01498"
     misc_feature    3046..3048
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:01501"
     misc_feature    3097..3204
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="Protein of unknown function (DUF1154); Region:
                     DUF1154; pfam06631"
                     /db_xref="CDD:148313"
     misc_feature    3331..3333
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    3331..3333
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /db_xref="HPRD:03479"
     misc_feature    3457..3882
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /note="PLC-beta C terminal; Region: PLC-beta_C; pfam08703"
                     /db_xref="CDD:204032"
     variation       415
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150241349"
     STS             452..1384
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /standard_name="Plcb1"
                     /db_xref="UniSTS:507150"
     exon            487..564
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       489
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:16994453"
     variation       493
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377750225"
     variation       501
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146304198"
     variation       504
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371499786"
     variation       508
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191106606"
     variation       516
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374402412"
     variation       525
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368510730"
     exon            565..633
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     exon            634..771
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       670
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199888561"
     variation       672
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138183168"
     variation       673
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200016726"
     variation       674
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375710411"
     variation       675
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200521017"
     variation       718
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373051695"
     exon            772..851
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       793
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201510657"
     variation       796
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369124253"
     variation       819
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142874818"
     variation       837
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373476629"
     variation       843
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200598979"
     variation       845
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:45496299"
     variation       851
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148738915"
     exon            852..905
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       873
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202085165"
     variation       889
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142186851"
     exon            906..981
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       962
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:78758453"
     variation       969
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150770296"
     exon            982..1082
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       1014
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151006778"
     variation       1024
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200713241"
     variation       1026
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:140899287"
     variation       1047
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184317533"
     variation       1077
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145276029"
     exon            1083..1249
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       1101
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147567110"
     variation       1111
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200567140"
     variation       1114
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372097607"
     variation       1115
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:13037181"
     variation       1116
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:13041270"
     variation       1125
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375123870"
     variation       1184
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369226956"
     variation       1239
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147648227"
     exon            1250..1396
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       1262
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370605921"
     variation       1266
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141935046"
     variation       1276
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149661663"
     variation       1299
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374061975"
     variation       1300
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370525961"
     variation       1306
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373633394"
     variation       1311
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:6056003"
     variation       1312
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368967370"
     variation       1329
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182563538"
     variation       1362
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372723242"
     variation       1377
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375950955"
     exon            1397..1554
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       1471
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199900846"
     variation       1514
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201807011"
     exon            1555..1637
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       1575
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202109404"
     variation       1617
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148848282"
     exon            1638..1722
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       1662
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143366963"
     exon            1723..1900
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       1802
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368448785"
     variation       1803
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201789409"
     variation       1820
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:146833633"
     variation       1821
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:13042785"
     variation       1833
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372481162"
     variation       1852
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:13043353"
     variation       1856
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:45608240"
     variation       1857
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:13042803"
     variation       1878
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145869401"
     variation       1889
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200375635"
     variation       1899
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374258684"
     exon            1901..1968
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       1913
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150686631"
     variation       1914
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141857911"
     variation       1926
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199565459"
     variation       1932
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201832361"
     variation       1938
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150189968"
     variation       1946
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367767018"
     variation       1960
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138851178"
     exon            1969..2065
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       2004
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:149364174"
     variation       2031
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147407762"
     exon            2066..2150
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       2139
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370361540"
     variation       2148
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143755415"
     exon            2151..2275
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       2170
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:370981396"
     variation       2172
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147227102"
     variation       2268
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:45492700"
     exon            2276..2430
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       2301..2302
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:11484096"
     variation       2302..2303
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:34975251"
     variation       2331
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200073364"
     variation       2348
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369668806"
     variation       2394
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373550621"
     variation       2415
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142083540"
     exon            2431..2595
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       2449
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140292070"
     variation       2469
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3761170"
     variation       2475
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189186909"
     variation       2499
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139095432"
     variation       2514
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3761169"
     variation       2578
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:61755434"
     variation       2586
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:8118206"
     exon            2596..2695
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       2666
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377440334"
     variation       2673
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202079822"
     exon            2696..2800
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       2715
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145778961"
     variation       2717
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:6086575"
     variation       2738
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112272450"
     variation       2741
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202199288"
     variation       2792
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377053037"
     exon            2801..2910
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       2861
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146646749"
     variation       2899
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144264179"
     exon            2911..3043
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       2937
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:141433824"
     variation       2938
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368627128"
     variation       2951
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201764744"
     variation       2952
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2076413"
     variation       2957
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184436336"
     variation       2975
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148288081"
     exon            3044..3097
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       3060
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:142813933"
     exon            3098..3317
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       3115
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147055196"
     variation       3165
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138373296"
     variation       3184
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143664316"
     variation       3185
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147191017"
     variation       3197
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113429373"
     variation       3228
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35245209"
     variation       3240
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:202226833"
     variation       3255
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149312175"
     variation       3294
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368328261"
     variation       3307
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372269921"
     exon            3318..3498
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       3333
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369387650"
     variation       3334
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371547145"
     variation       3354
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:45464693"
     variation       3366
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148394888"
     variation       3374
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:142497580"
     variation       3375
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2235613"
     variation       3426
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139859188"
     exon            3499..3575
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       3503
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75820839"
     variation       3507
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61755436"
     variation       3516
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141102170"
     exon            3576..3665
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       3589
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:41275588"
     variation       3621
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:58386879"
     exon            3666..3723
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       3687
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:370182417"
     variation       3691
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376179077"
     exon            3724..3810
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       3724
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2294597"
     variation       3734
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148936543"
     exon            3811..3928
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       3813
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113051085"
     variation       3834
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375157750"
     variation       3837
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368188429"
     variation       3884
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138434221"
     variation       3888
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372137190"
     exon            3929..7207
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /inference="alignment:Splign:1.39.8"
     variation       3952
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142432676"
     STS             3957..4154
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /standard_name="A007B46"
                     /db_xref="UniSTS:3741"
     variation       4017
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145966488"
     variation       4024
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369783351"
     STS             4032..4133
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /standard_name="D20S580E"
                     /db_xref="UniSTS:7842"
     variation       4038
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200309017"
     variation       4051
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148236379"
     variation       4055
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:28390202"
     variation       4074
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200781362"
     variation       4089
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186429469"
     variation       4094
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:199568969"
     variation       4095
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:190019296"
     variation       4111
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200558916"
     variation       4112
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150804955"
     variation       4140
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202009902"
     STS             4146..4297
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /standard_name="D20S594E"
                     /db_xref="UniSTS:37163"
     variation       4148
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138077430"
     variation       4182
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142723816"
     variation       4198
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368625100"
     variation       4204
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372734005"
     variation       4247
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:146432082"
     variation       4253
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41275590"
     variation       4314
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:41275592"
     variation       4324
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:138231814"
     variation       4413
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:374099954"
     variation       4451
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376353155"
     variation       4509
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182132458"
     variation       4532..4533
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="aat"
                     /db_xref="dbSNP:147873196"
     variation       4533..4534
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="aat"
                     /replace="ata"
                     /db_xref="dbSNP:369758360"
     variation       4538
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187192857"
     variation       4619
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:6039314"
     variation       4753
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370143156"
     variation       4763
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192618264"
     variation       4905
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:16995375"
     variation       4947
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:6077450"
     variation       5011
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115731722"
     variation       5080
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:6077451"
     variation       5095
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:6056227"
     variation       5098
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41275594"
     variation       5118
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41275596"
     variation       5147
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:139726114"
     variation       5184
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:188506001"
     variation       5330..5331
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:34193042"
     variation       5351
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377303019"
     variation       5402..5403
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:373951022"
     variation       5497..5499
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="aat"
                     /db_xref="dbSNP:200025372"
     STS             5503..5650
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /standard_name="A006R17"
                     /db_xref="UniSTS:39851"
     variation       5694
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:116163517"
     variation       5707
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:77690948"
     variation       5733
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:111518686"
     variation       5800
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:193061195"
     variation       5826
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:41275598"
     variation       5837
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1047381"
     variation       5863
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:708910"
     variation       5954
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:73089700"
     variation       5963
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185730557"
     variation       6020
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:6056228"
     variation       6027
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200559753"
     variation       6058
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:189287307"
     variation       6109..6112
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="actt"
                     /db_xref="dbSNP:140751915"
     variation       6110..6113
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="ctta"
                     /db_xref="dbSNP:78940282"
     variation       6132..6133
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="tctt"
                     /db_xref="dbSNP:202098034"
     variation       6152
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11906786"
     variation       6196
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191314641"
     variation       6252..6254
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="gaa"
                     /db_xref="dbSNP:140743311"
     variation       6355
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:139585499"
     variation       6651
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113838596"
     variation       6666
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1047383"
     variation       6741
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:41275600"
     variation       6868..6869
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35474573"
     STS             6901..6998
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /standard_name="RH78853"
                     /db_xref="UniSTS:46819"
     variation       6945
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:188626146"
     variation       7028
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181420228"
     variation       7056
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:374699222"
     variation       7091
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:186428545"
     polyA_signal    7187..7192
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
     polyA_site      7207
                     /gene="PLCB1"
                     /gene_synonym="EIEE12; PI-PLC; PLC-154; PLC-I; PLC154;
                     PLCB1A; PLCB1B"
ORIGIN      
cactcgctctctccctctgtgtatagaggatgtgctgaatggtgcgctttgaggcggcggcggcggaggagcagaatccgccgcgactggcagcctcggctgaccggctcggcttctcttcgccttccgaggctcctcatccaccgcgggctccagacctcgcgtcccgcccggggcatggccgggcgctgcgcccccgcgcgctctgcctgctgagcggcgccggagggaggtgcggaggccgggaggccggggaggccggcggggagcagagtcgagcgcctccggagcagagaaaggagcccgcgccccgcgccccgcgccccgcgcacggtccccagtccctgccgcgctcgcccgggccgcccggagcccagatgagcccagatggccggggctcaacccggagtgcacgccttgcaactcaagcccgtgtgcgtgtccgacagcctcaagaagggcaccaaattcgtcaagtgggatgatgactcaactattgttactccaattattttgaggactgaccctcagggatttttcttttactggacagatcaaaacaaggagacagagctactggatctcagccttgtcaaagatgccagatgtgggagacacgccaaagctcccaaggaccccaaattacgtgaacttttggatgtggggaacatcgggcgcctggagcagcgcatgatcacagtggtgtatgggcctgacctcgtgaacatctcccatttgaatctcgtggctttccaagaagaagtggccaaggaatggacaaatgaggttttcagtttggcaacaaacctgctggcccaaaacatgtccagggatgcatttctggaaaaagcctatactaaacttaagctgcaagtcactccagaagggcgtattcctctcaaaaacatatatcgcttgttttcagcagatcggaagcgagttgaaactgctttagaggcttgtagtcttccatcttcaaggaatgattcaatacctcaagaagatttcactccagaagtgtacagagttttcctcaacaacctttgccctcgacctgaaattgataacatcttttcagaatttggtgcaaaaagcaaaccatatcttaccgttgatcagatgatggattttatcaaccttaagcagcgagatcctcggcttaatgaaatactttatccacctctaaaacaagagcaagtccaagtattgattgagaagtatgaacccaacaacagcctcgccagaaaaggacaaatatcagtggatgggttcatgcgctatctgagtggagaagaaaacggagtcgtttcacctgagaaactggatttgaatgaagacatgtctcagcccctttctcactatttcattaattcctcgcacaacacctacctcacagctggccaactggctggaaactcctctgttgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtggagctggactgctggaagggacggactgcagaagaggaacctgtcatcacccatggcttcaccatgacaactgaaatatctttcaaggaagtgatagaagcaattgcggagtgtgcatttaagacttcaccttttccaattctcctttcgtttgagaaccatgtggattccccaaagcagcaagccaagatggcggagtactgccgactgatctttggggatgcccttctcatggagcccctggaaaaatatccactggaatctggagttcctcttccaagccctatggatttaatgtataaaattttggtgaaaaataagaagaaatcacacaagtcatcagaaggaagcggcaaaaagaagctctcagaacaagcctccaacacctacagtgactcctccagcatgttcgagccctcatccccaggagccggagaagctgatacggaaagtgacgacgacgatgatgatgatgactgtaaaaaatcttcaatggatgaggggactgctggaagtgaggctatggccacagaagaaatgtctaatctggtgaactatattcagccagtcaagtttgagtcatttgaaatttcaaaaaaaagaaataaaagttttgaaatgtcttccttcgtggaaaccaaaggacttgaacaactcaccaagtctccagtggaatttgtagaatataacaaaatgcagcttagcaggatatatccaaaaggaacacgtgtggattcatccaactatatgcctcagctcttctggaatgcaggttgtcagatggtggcacttaatttccagacaatggacctggctatgcaaataaatatggggatgtatgaatacaacgggaagagtggctacagattgaagccagagttcatgaggaggcctgacaagcattttgatccatttactgaaggcatcgtagatgggatagtggcaaacactttgtctgttaagattatttcaggtcagtttctttctgataagaaagttgggacttacgtggaagtagatatgtttggtttgcctgtggatacaaggaggaaggcatttaagaccaaaacatcccaaggaaatgctgtgaatcctgtctgggaagaagaacctattgtgttcaaaaaggtggttcttcctactctggcctgtttgagaatagcagtttatgaagaaggaggtaaattcattggccaccgtatcttgccagtgcaagccattcggccaggctatcactatatctgtctaaggaatgaaaggaaccagcctctgacgctgcctgctgtctttgtctacatagaagtgaaagactatgtgccagacacatatgcagatgtcatcgaagctttatcaaacccaatccgatatgtgaacctgatggaacagagagctaagcaattggctgctttgacactggaagatgaagaagaagtaaagaaagaggctgatcctggagaaacaccatcagaggctccaagtgaagcgagaacgactccagcagaaaatggggtgaatcacactacaaccctgacacccaagccaccctcccaggctctccacagccagccagctccaggttctgtaaaggcacctgccaaaacagaagatcttattcagagtgtcttaacagaagtggaagcacagaccatcgaagaactaaagcaacagaaatcgtttgtgaaacttcaaaagaaacactacaaagaaatgaaagacctggttaagagacaccacaagaaaaccactgaccttatcaaagaacacactaccaagtataatgaaattcagaatgactacttgagaaggagagccgctttggaaaagtccgccaaaaaggacagtaagaaaaaatcggaacccagcagccctgatcatggttcatcaacgattgagcaagacctcgctgctctggatgctgaaatgacccaaaagttaatagacttgaaggacaaacaacagcagcagctgcttaatcttcggcaagaacagtattatagtgaaaaataccagaagcgagaacatattaaactgcttattcaaaagttgacggatgtcgcagaagagtgtcagaacaatcagttaaagaagctcaaagaaatctgtgagaaagaaaagaaagaattaaagaagaaaatggataaaaagaggcaggagaagataacagaagctaaatccaaagacaaaagtcagatggaagaggagaagacagagatgatccggtcatatatccaggaagtggtgcagtatatcaagaggctagaagaagcgcaaagtaaacggcaagaaaaactcgtagagaaacacaaggaaatacgtcagcagatcctggatgaaaagcccaagggggaaggttcctcctcattcttgtcggaaacttgccatgaggatccctctgtttcccccaactttactccccccaaccctcaagctctcaagtggtgaccaccgtccttccggccagctgcaggtggagctggagcaagaataccaagacaaattcaaaagactgcccctcgagattttggaattcgtgcaggaagccatgaaaggaaagatcagtgaagacagcaatcacggttctgcccctctctccctgtcctcagaccctggaaaagtgaaccacaagactccctccagtgaggagctgggaggagacatcccaggaaaagaatttgatactcctctgtgaatgctcctgccaggccttcagaaattgcatggccactccagcgtcatcggactctctcttattacaaagatcactgcccaggaccatcttcccgagaagcatcccttagcctaaaatccacaccaaagggagagttccagaggaatccatgaagaattcccatgcccaggctccatgtgtcatgtggaaacctccacaggtctgctagtgaagaatgcatgtatgtgagatttttgttttctttccaatagcaaattcaaagcaagcaacttgcaggctccatggaacttttaatgaaggacagtgtcttctttgaagaaaatcaagctcgtgtttttattcgaagctctggtgtaaaatatttcaaagtcatagaaatagtttgagaaatgcatagcattatttaacactattgaacagccgactttgagcattgtttcttctaactgcccctcaactaccattatcttcaagtcaacatgcatattacattttcatcctttgctttgcaagcactggtggcttgcagtttgctaatttatttatcatagagtcatcaatgtatttgttgctgacatggttttattagatactgtagtgattcaaataagttttctatttgaaaaaaaaaatcacttgattgtatccttgcccagtgaagccatcctaagacttagcaatatggattgtacatttggctgcatgagcaagtcggccgcacacttccagacagtgtgctgtttgaattgactatttgcactcaaagtctgggtattcattggttattggcctgaaatgatcaaataactacaaatgatctgttgaataaaaatagttgagctgatatatgttaagcagatattcaatcagaatgaacaggttccggtggttattttgccgtttgacattttttatggttcatttatttttaatatagagaggaagattgaatatttatctagagaatacaaagacccacatgtaaatgataggtattatctccatgtatatatgtacccacttagtcatgtaagtgcatatacacatacacacacatgagtgtagacatgtgtttattaattgacaatgacccaaatctcttccacaagacttaaaaccaaattcagggacaaatggatagagaagaaaagggtcaaacatcgagattacatggatgttaaattatatggagacgctaagaaataattgatggagccattgatgcaaaccgaagtagatttagaacttatatgaatttgatttatattttgcaagatcaaaaattagatgttaagtatcagattttaagcttgttttaatggtcaaaaaattaggacagaaataatatggacatttattagtatcttccataatttttaagtctgacacatttctattttattctaacataaaaaaacttccattatatatttactaagtatatttaattcacttaactctgtctttataagttcctattttagatggaataagagaaacaaattatatcaaggtaaaactgatcaaaagcataattgaaagttctgaaaaaagaaaaataataatatgtagaaaaatgtaacttagagagtaacacatgaacattgaagttaaaacccagaagccagatgctcacagttttattttactttaaaataaacctgtctgactgtagctttgtgaaatatcttaaaacgcaaaaaccaattgtgtcctgaaaattgtttcaagaatttaatatttttatgaaaattattttatttaactttaagcaataactagagattacaattaaattttaatcaaaatgaaggcttagttcaaacataaggaaacagtgtttgattaaaaaaaacacatctagtaagacgtaaggggaaaatcacatcctctttggagatgattatattttgatctgaagggtttggggtgttcattagacacttaataaaacttaacttccaatgaaaaagaaatcttttgtaaatcattctacttttgcactttgaaagaaaggcgttaatcataaagaagcaagaatggtcaaaatcgaatgctgcatttttataaacaaaattacagactgtctgaaattgaagaagaatgaactaataatagcattcataaccaaacacaatgatgattattgcagaacattgtatcacattttagtccagagatagaataaagttgaataaccttgacttacacaaaactgttttggtagttggatttcattatcttagtgaatttagtcattttacaatatgtttgtatttggccatttactgtaatcacatttttatatctgtacaatgacactttttgcagttgtggggtagtgtgtaacactgtccatcttgcatcattgaaactactacaatgatactatcatttaataatattaatattacttgaaatagactaagataaagaaaaggggtctgtatgatgtgcagttttgtgcctttatgtatttgccttgttctttgtcgaatgtgtgaaattccgtactgtggtttttcctataatagaaagtagagctgtgtattaaattagactgtgtctctctgatacctttacactactgagaatagcatggttttggccatgtaaaccaattttcaaagttctaatgacatagccatgtgtttttggttttttatatttcattttaaaatttgagtatcaccatacattaattaatactcctgtagtagataagctgtcattaagtaattcccaaaaaaagggccatttgcttgcattactttgaatttaatgttgcgcttgtgcactgtgttaatattgtttgtgatggattggacgttgtgactcttgccttttaagaagaaaaaaaagataggacaaagtatttgaagctcttaaaatgtacatattttggttcttctatctcaaattatttaaaatgcataattcacatttttgtaataattctatgcaattttgtggcatgatgtttcttccacttgtaattttatgtgctttcatcacaaatccaaaggaaagaataaaaatttcttaacacaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:23236 -> Molecular function: GO:0004435 [phosphatidylinositol phospholipase C activity] evidence: ISS
            GeneID:23236 -> Molecular function: GO:0004435 [phosphatidylinositol phospholipase C activity] evidence: NAS
            GeneID:23236 -> Molecular function: GO:0004871 [signal transducer activity] evidence: IEA
            GeneID:23236 -> Molecular function: GO:0005096 [GTPase activator activity] evidence: IDA
            GeneID:23236 -> Molecular function: GO:0005509 [calcium ion binding] evidence: IEA
            GeneID:23236 -> Molecular function: GO:0005516 [calmodulin binding] evidence: IPI
            GeneID:23236 -> Molecular function: GO:0005521 [lamin binding] evidence: IEA
            GeneID:23236 -> Molecular function: GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding] evidence: IDA
            GeneID:23236 -> Molecular function: GO:0019899 [enzyme binding] evidence: IPI
            GeneID:23236 -> Molecular function: GO:0042803 [protein homodimerization activity] evidence: ISS
            GeneID:23236 -> Biological process: GO:0000086 [G2/M transition of mitotic cell cycle] evidence: ISS
            GeneID:23236 -> Biological process: GO:0007165 [signal transduction] evidence: NAS
            GeneID:23236 -> Biological process: GO:0007213 [G-protein coupled acetylcholine receptor signaling pathway] evidence: ISS
            GeneID:23236 -> Biological process: GO:0007215 [glutamate receptor signaling pathway] evidence: ISS
            GeneID:23236 -> Biological process: GO:0007268 [synaptic transmission] evidence: TAS
            GeneID:23236 -> Biological process: GO:0007613 [memory] evidence: ISS
            GeneID:23236 -> Biological process: GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] evidence: ISS
            GeneID:23236 -> Biological process: GO:0016042 [lipid catabolic process] evidence: IEA
            GeneID:23236 -> Biological process: GO:0021987 [cerebral cortex development] evidence: ISS
            GeneID:23236 -> Biological process: GO:0032735 [positive regulation of interleukin-12 production] evidence: ISS
            GeneID:23236 -> Biological process: GO:0035556 [intracellular signal transduction] evidence: IEA
            GeneID:23236 -> Biological process: GO:0035722 [interleukin-12-mediated signaling pathway] evidence: IDA
            GeneID:23236 -> Biological process: GO:0035723 [interleukin-15-mediated signaling pathway] evidence: IDA
            GeneID:23236 -> Biological process: GO:0040019 [positive regulation of embryonic development] evidence: ISS
            GeneID:23236 -> Biological process: GO:0043547 [positive regulation of GTPase activity] evidence: IDA
            GeneID:23236 -> Biological process: GO:0043647 [inositol phosphate metabolic process] evidence: TAS
            GeneID:23236 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
            GeneID:23236 -> Biological process: GO:0045444 [fat cell differentiation] evidence: IEA
            GeneID:23236 -> Biological process: GO:0045663 [positive regulation of myoblast differentiation] evidence: ISS
            GeneID:23236 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: ISS
            GeneID:23236 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: ISS
            GeneID:23236 -> Biological process: GO:0046330 [positive regulation of JNK cascade] evidence: IDA
            GeneID:23236 -> Biological process: GO:0046488 [phosphatidylinositol metabolic process] evidence: ISS
            GeneID:23236 -> Biological process: GO:0048009 [insulin-like growth factor receptor signaling pathway] evidence: ISS
            GeneID:23236 -> Biological process: GO:0048639 [positive regulation of developmental growth] evidence: ISS
            GeneID:23236 -> Biological process: GO:0060466 [activation of meiosis involved in egg activation] evidence: ISS
            GeneID:23236 -> Biological process: GO:0070498 [interleukin-1-mediated signaling pathway] evidence: IDA
            GeneID:23236 -> Biological process: GO:0080154 [regulation of fertilization] evidence: ISS
            GeneID:23236 -> Biological process: GO:1900087 [positive regulation of G1/S transition of mitotic cell cycle] evidence: ISS
            GeneID:23236 -> Biological process: GO:2000344 [positive regulation of acrosome reaction] evidence: ISS
            GeneID:23236 -> Biological process: GO:2000438 [negative regulation of monocyte extravasation] evidence: ISS
            GeneID:23236 -> Biological process: GO:2000560 [positive regulation of CD24 biosynthetic process] evidence: ISS
            GeneID:23236 -> Cellular component: GO:0000790 [nuclear chromatin] evidence: ISS
            GeneID:23236 -> Cellular component: GO:0005634 [nucleus] evidence: NAS
            GeneID:23236 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:23236 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:23236 -> Cellular component: GO:0016607 [nuclear speck] evidence: IDA
            GeneID:23236 -> Cellular component: GO:0031965 [nuclear membrane] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_877398 -> EC 3.1.4.11

by @meso_cacase at DBCLS
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