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2019-03-24 19:53:00, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_182493               7998 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens myosin light chain kinase 3 (MYLK3), mRNA.
ACCESSION   NM_182493
VERSION     NM_182493.2  GI:146219831
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7998)
  AUTHORS   Al-Sadi,R., Ye,D., Dokladny,K. and Ma,T.Y.
  TITLE     Mechanism of IL-1beta-induced increase in intestinal epithelial
            tight junction permeability
  JOURNAL   J. Immunol. 180 (8), 5653-5661 (2008)
   PUBMED   18390750
  REMARK    GeneRIF: data indicate that the IL-1beta-induced increase in MLCK
            protein expression and Caco-2 TJ permeability was mediated by an
            increase in MLCK expression and activity and by an
            NF-kappaB-dependent increase in MLCK gene transcription
REFERENCE   2  (bases 1 to 7998)
  AUTHORS   Chan,J.Y., Takeda,M., Briggs,L.E., Graham,M.L., Lu,J.T.,
            Horikoshi,N., Weinberg,E.O., Aoki,H., Sato,N., Chien,K.R. and
            Kasahara,H.
  TITLE     Identification of cardiac-specific myosin light chain kinase
  JOURNAL   Circ. Res. 102 (5), 571-580 (2008)
   PUBMED   18202317
REFERENCE   3  (bases 1 to 7998)
  AUTHORS   Seguchi,O., Takashima,S., Yamazaki,S., Asakura,M., Asano,Y.,
            Shintani,Y., Wakeno,M., Minamino,T., Kondo,H., Furukawa,H.,
            Nakamaru,K., Naito,A., Takahashi,T., Ohtsuka,T., Kawakami,K.,
            Isomura,T., Kitamura,S., Tomoike,H., Mochizuki,N. and Kitakaze,M.
  TITLE     A cardiac myosin light chain kinase regulates sarcomere assembly in
            the vertebrate heart
  JOURNAL   J. Clin. Invest. 117 (10), 2812-2824 (2007)
   PUBMED   17885681
  REMARK    GeneRIF: Integrated cDNA expression analysis of failing human
            myocardia uncovered a novel protein kinase, cardiac-specific myosin
            light chain kinase (cardiac-MLCK), which acts on MLC2v.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ247087.1, DA561361.1, CR739116.1, AC007225.2 and AL691746.1.
            On May 3, 2007 this sequence version replaced gi:32698825.
            
            Summary: Phosphorylation of cardiac myosin heavy chains (see MYH7B,
            MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase,
            such as MYLK3, potentiates the force and rate of cross-bridge
            recruitment in cardiac myocytes (Chan et al., 2008 [PubMed
            18202317]).[supplied by OMIM, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ247087.1, BC109096.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025082, ERS025083 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-653               AJ247087.1         1-653
            654-1101            DA561361.1         122-569
            1102-2668           AJ247087.1         1102-2668
            2669-3146           CR739116.1         83-560
            3147-7880           AC007225.2         178378-183111
            7881-7998           AL691746.1         27-144              c
FEATURES             Location/Qualifiers
     source          1..7998
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q11.2"
     gene            1..7998
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /note="myosin light chain kinase 3"
                     /db_xref="GeneID:91807"
                     /db_xref="HGNC:29826"
                     /db_xref="MIM:612147"
     exon            1..593
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    27..29
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /note="upstream in-frame stop codon"
     CDS             117..2576
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /EC_number="2.7.11.18"
                     /note="MLC kinase; cardiac-MyBP-C associated Ca/CaM
                     kinase; putative myosin light chain kinase 3;
                     cardiac-MyBP-C-associated Ca/CaM kinase; cardiac-MLCK"
                     /codon_start=1
                     /product="myosin light chain kinase 3"
                     /protein_id="NP_872299.2"
                     /db_xref="GI:146219832"
                     /db_xref="CCDS:CCDS10723.2"
                     /db_xref="GeneID:91807"
                     /db_xref="HGNC:29826"
                     /db_xref="MIM:612147"
                     /translation="
MSGTSKESLGHGGLPGLGKTCLTTMDTKLNMLNEKVDQLLHFQEDVTEKLQSMCRDMGHLERGLHRLEASRAPGPGGADGVPHIDTQAGWPEVLELVRAMQQDAAQHGARLEALFRMVAAVDRAIALVGATFQKSKVADFLMQGRVPWRRGSPGDSPEENKERVEEEGGKPKHVLSTSGVQSDAREPGEESQKADVLEGTAERLPPIRASGLGADPAQAVVSPGQGDGVPGPAQAFPGHLPLPTKVEAKAPETPSENLRTGLELAPAPGRVNVVSPSLEVAPGAGQGASSSRPDPEPLEEGTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEMDTPGEMLMTGRGSLGPTLTTEAPAAAQPGKQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQESSSPGGVKAEEEQRAGAEPGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSPAPPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
"
     misc_feature    1653..2426
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /note="Serine/Threonine protein kinases, catalytic domain;
                     Region: S_TKc; smart00220"
                     /db_xref="CDD:197582"
     misc_feature    1677..2417
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /note="Catalytic domain of Protein Kinases; Region: PKc;
                     cd00180"
                     /db_xref="CDD:173623"
     misc_feature    order(1677..1691,1701..1703,1740..1742,1746..1748,
                     1833..1835,1881..1892,1902..1904,1908..1910,2022..2024,
                     2028..2030,2034..2039,2043..2045,2082..2084,2091..2093,
                     2136..2147)
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /note="active site"
                     /db_xref="CDD:173623"
     misc_feature    order(1677..1691,1701..1703,1740..1742,1746..1748,
                     1833..1835,1881..1892,1902..1904,2022..2024,2028..2030,
                     2034..2039,2043..2045,2082..2084)
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:173623"
     misc_feature    order(1689..1691,1902..1904,1908..1910,2022..2024,
                     2028..2030,2034..2036,2091..2093,2136..2147)
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173623"
     misc_feature    order(2079..2099,2136..2147)
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /note="activation loop (A-loop); other site"
                     /db_xref="CDD:173623"
     exon            594..684
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            685..1117
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            1118..1578
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            1579..1684
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            1685..1778
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            1779..1888
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            1889..2030
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            2031..2101
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            2102..2230
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            2231..2383
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            2384..2516
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     exon            2517..7998
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /inference="alignment:Splign:1.39.8"
     variation       3147
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1645939"
     misc_feature    3583..3648
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /note="GRAIL 2 excellent exon, frame 1"
     STS             3753..3919
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /standard_name="G35510"
                     /db_xref="UniSTS:44150"
     STS             3795..3883
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /standard_name="D8S2279"
                     /db_xref="UniSTS:473907"
     STS             4336..4963
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /standard_name="D1S1361"
                     /db_xref="UniSTS:149557"
     STS             4521..4784
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /standard_name="L17705"
                     /db_xref="UniSTS:66091"
     STS             4538..4878
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /standard_name="GDB:313783"
                     /db_xref="UniSTS:13512"
     STS             4796..4905
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /standard_name="D10S275"
                     /db_xref="UniSTS:147992"
     variation       5623
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:698417"
     variation       5774
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:698416"
     STS             5923..7619
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /standard_name="GDB:631802"
                     /db_xref="UniSTS:158429"
     variation       6682
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:425556"
     variation       7290
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:615366"
     STS             7475..7607
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /standard_name="D7S2067E"
                     /db_xref="UniSTS:151120"
     variation       7928..7929
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75112486"
     variation       7929
                     /gene="MYLK3"
                     /gene_synonym="caMLCK; MLCK; MLCK2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370159"
ORIGIN      
aggagtctgtcagctacggaggacaatgaccttgcagacaccaccgcctgagtgagaaccaggggtctgtgcctctcctcattccccgctcttgcccttgtcaagcctgcaccagcatgtcaggaacctccaaggagagtctggggcatggggggctgccagggttgggcaagacctgcttaacaaccatggacacaaagctgaacatgctgaacgagaaggtggaccagctcctgcacttccaagaagatgtcacagagaagttgcagagcatgtgccgagacatgggccacctggagcggggcctgcacaggctggaggcctcccgggcaccgggcccgggcggggctgatggggttccccacattgacacccaggctgggtggcccgaggtcctggagctggtgagggccatgcagcaggatgcggcccagcacggtgccaggctggaggccctcttcaggatggtggctgcggtggacagggccatcgctttggtgggggccacgttccagaaatcaaaggtggcggatttcctcatgcaggggcgtgtgccctggaggagaggcagcccaggtgacagccctgaggagaataaagagcgagtggaagaagagggaggaaaaccaaagcatgtgctgagcaccagtggggtgcagtctgatgccagggagcctggggaagagagccagaaggcggacgtgctggaggggacagcggagaggctgccccccatcagagcgtcagggctgggagctgaccccgcccaggcagtggtctcaccgggccagggagatggtgttcctggcccagcccaggcattccctggccacctgcccctgcccacaaaggtggaagccaaggctcctgagacacccagcgagaacctcaggactggcctggaattggctccagcacccggcagggtcaatgtggtctccccgagcctggaggttgcaccaggtgcaggacaaggagcatcgtccagcaggcctgaccctgagcccttagaggaaggcacgaggctgactccagggcctggccctcagtgcccagggcctccagggctgccagcccaggccagggcaacccacagtggtggagaaacacctccaaggatctccatccacatacaagagatggatactcctggggagatgctgatgacaggcaggggcagccttggacccaccctcaccacagaggctccagcagctgcccagccaggcaagcagggcccacctgggaccgggcgctgcctccaagcccctgggactgagcccggagaacagacccctgaaggagccagagagctctccccgctgcaggagagcagcagccccgggggagtgaaggcagaggaggagcaaagggctggggccgagcctggcacgagaccaagcttggccaggagtgacgacaatgaccacgaggttggggccctgggcctgcagcagggcaaaagcccaggggcgggaaaccctgagcctgagcaggactgtgcagccagggctccggtgagagctgaagcagtaaggaggatgcccccaggcgccgaggctggcagcgtggttctggatgacagtccggccccaccagctccttttgaacaccgggtagtgagcgtcaaggagacctccatctctgcgggttacgaggtgtgccagcacgaagtcttgggagggggtcggtttggccaggtccacaggtgcacagagaagtccacaggcctcccactggctgccaagatcatcaaagtgaagagcgccaaggaccgggaggacgtgaagaacgagatcaacatcatgaaccagctcagccacgtgaacctgatccagctctatgacgccttcgagagcaagcacagctgcacccttgtcatggagtacgtggacgggggtgagctcttcgaccggatcacagatgagaagtaccacctgactgagctggatgtggtcctgttcaccaggcagatctgtgagggtgtgcattacctgcaccagcactacatcctgcacctggacctcaagccggagaacatattgtgcgtcaatcagacaggacatcaaattaagatcattgactttgggctggccagaaggtacaagcctcgagagaagctgaaggtgaacttcggcactcctgagttcctggccccagaagtcgtcaattatgagtttgtctcattccccacagacatgtggagtgtgggagtcatcacctacatgctactcagtggcttgtccccatttctaggggaaacagatgcagagaccatgaatttcattgtaaactgtagctgggattttgatgctgacacctttgaagggctctcggaggaggccaaggactttgtttcccggttgctggtcaaagagaagagctgcagaatgagtgccacacagtgcctgaaacacgagtggctgaataatttgcctgccaaagcttcaagatccaaaactcgtctcaaatcccaactactgctgcagaaatacatagctcaaagaaaatggaagaaacatttctatgtggtgactgctgccaacaggttaaggaaatttccaacttctccctaatcttcaactctgctgctccaatgggtccagaaattactgaggccagtggtgaagtgaagagatgactcaaacatttaaataatttggctttttggtattattgattccacttattttgtaaaaatggttatggctgctgccttccttgtggatgaaaagtggctgtaaagaagcttcctaagaacgtttttttctgccttgtaagatcactacgtgtgaaatgctctgagtacctttcaaatatacctacttttggtggtaagtgtagggatgctttaggtaggtactttgcatctgtcgaatttaaattctaaactcacactgattaaggaactcagtagactactttgcaggggccatgttattcagtgttatctcctccagtacaaagaattcctagaattttgatttgctcaggtgtgagctgacattttattgtactaccccattcttgtgttaagccatgtggatttaggacagtgatcttcaaacttgctttaacttatgctcccttttgagaatcagcatcacttgaaatgtcaaaatatgtcaactctcatagccaaatcaaagaagtgatcattttgactgtgctttttaaatctccacacacctccacctctctcctaattctgcctgtcttaacccctctgtcttagttataaatttctggtcttgtaagtctggaagctgataggcaatttatgaaagagataagaatgtaatgaggttccgctttctgagaaacacagaaatgatacatcctgagacataaaggaaagctgctcttctgctgcctcaggctgtagcactctcaatgttgtcactctacacatacactttctatatacatgtacagttgacccttgaacagggtttgaattgcagtcaacttaaatgtggattttctttcacctttgtcacccctgagacagcaacaccatgctctcctcttcatcccactctgcagcctactcaacaggaagatgatgaagatgaacacctttatgatgatccactttcacttaatgaatagtaaacatatgttttcctccttatgattttagtaacttttctctagcttactttattgtaagaatacagtatataagctgggtgtggtggctcatgcccataatcccagcactttgggaggctgaggcaggcagatcacttgaggtcaggagttcaagaccagcctggccaacacagtgaaaccccatctctactaaaaatacaaaaattagtggggcgtggtggcggatgcctgtaatgtcagctactctggaggctgaggcaggagaactgcttgaacctgggaggtggagtttgcagtgagccaagattgcaccactgcactccagcctaggcaacagagcaagactccgtctcaaaaaaaaaaaaaaaaaagaatacagtatatgtatatatacacacacacaaacacacacacacacgaacacatatgtgtgtatgggtattaactgactgtttatattattgatagggcttccagtcaacattaggctattagtagttaagtttttggggagacaaaagttatactcagattttctactgcaagggggtaggcactcctaaccctcacattgttcaagggtccactgtacatttaaacacttttctatatgcattagagtagccctgtcatcccttcactgaaatcatactgttctcaacatggcaagcaactaacacttttttttttttttgagacagggtctcactctgttgcccaggctgcagtgcagtggtgtgatcttggctcactgtagcctccgcctcctgggctcaggcgatcatgagtacctgggaccataggtgcccgctactacacccagctaatttttgtatttttagtggagatagggttttgccatgttgcccaacctggtcttgagctcaagcgatccacctgccccagcctcccaaagtgctgggattataggtgtgagccaccacacccagcttcaactaacacatttacgaacttgtatacatgtatatttagatactttaccaacttgtaaaatggttaaaggagtactttattatgaaaaaatatacaatctttaaaatttccttacttctacatgatttttgtgctattcccatttttttcctcaggtgagcagctttagttttttattttttttgagagagtcttcctctgtcacccaggctggagtgcactggtgtgttcttggctcactgcaacctctgcctcccgggttcaagtgatcttgtgcctcagcctcccaggtagctgggattacaggcgtgtgctgccacgcccagctaatttttgtatttttggtagagatggggttttgccatgttggccaggctggtctcgaactcctgacctcagatgatccacctgtcttggcctcccaaagagctgggaatataggcatgagccactgtgcttggcctcaggtgagcagctttagtcaatgttgtgaattttagattttaattagacatgcaacagtttcactacctttcaggatttttgtcctgtaacagaggctcttgctttttgacagagaggtaggcaggtggagaggttatcctgctgctgcagttctcaagttgttaagtttcctctggaaggctaacccttgttgggaactaacagtttcaataccagcaagtctaggcctgctccaagttggtcagctgaagaatgaacatcagaagacacagctgctgaaagttgtcctttgatgagacagtgatagtgatttggtaaaatgtcttattttttaaatgtcagttatctttctttaaaaggttttttgagggcagcctccagaaggagctagagagtatattttatagttctattgtggttcataccctgttttcgacttaagattctggagaatgctatgaaacatctccccagaaaaagacagttaattaccatatctagagcagcactgcccaacaaaaatatagtacaggctatacacataattaaaacatttctagtagcttctctaacaaaacccattgaaagccaattttaataatttatataacttagtgtatcaaaaatatttcaatatgtaatcaacataaaattgagatactttaccagctactagggaggctgaggccagagaatcacttgaacccagggggtggaggttgcagtgagccaagatcacaccattgaactccagcctgggcaacaagagcaaaactccgtctcaaaaaaaaagagatattttatattctttttctcatactaagtctcaaaaatctggtatattttacacttaaaaacacatgtcaaggctaggcatggtggctcacatctgtaatcccagcactttgggaggccaaggtgggcagattgctggccaacatggtaaaaccccatctctaaaaatataaaaattagctgggcgtggtggcgcatacctgtaatcccagctacttgggaggctaaggcacaagaatcacttaaacaggaggcaggggttgcagtgagctgagatcacaccactgcactccagcctgggtggcagagcaaaactttgtccccacccctgacaaaaaacaaacaaacaaacaaaacaaaaaaaaacctgtcaattcagatgctaggttttcatcagacgtacttaatctgtatttagatttcttaaaacttactgtggaaaatgtatttacatactcaagttgtttgaaacataactcactgttttccaataactgaagtatccacttttacatgtattaaaattaaataaaattagaaattcagttctgcagttgcactagccacattttaagtgtttaatagccacacgtggttagtggcatctatattggacagggcagatctagagagaatcctgtatctaacaattttaatttttttccctttatgctgttattccttacctagagaaacaatttccctccaaagttcctttgaggggtctgtttaggccaggccaacacaagtgacctatgtggattttagcatcctttttttgaaatttgaggttttatgaagcttgagtttttctggatatttttagtaatttgctggtgtgtacttagctcaaatacttgattgcaactgtgttgggtcaactatttctaatgggacttttccatttgcatgtacagtcactggaaactgctgggcagagaaactctaaaaggtagttggggcacactttttccacctgtcagattggtgaagaattggtgaggctgtggggaaaatggcattctcccacttttgatggatatgtatccaaataaaagtcattcccatgctttctttcatccagaaattttatttctagaaatttatccctccgtacttgaacaattgtatagagatttattcaaaatgatgtttactatagcactgttgctaatggcccagtaaaaacaaccaacacatgcctattagtttggttttagttaaatgaattttgccacatccatgtagtggaatacctcacagctgttatagatagatctagatatactgaaagccattttttcttaaattatagaatgtatatatggtatcatcccatttgtgaagagacatatgcttatatgtgcattaaaaaaccgtaggatatgcaagaaacttaacagtggagtgtgaaaagtgggtgattgggagagggggaattccacttttcatttatctttctgaaccttttgaatcttttttttttttttttttacaatgagcatgtattcctttttttttttttctttccaagatggagtctcactctgttgccaggctggagtgcagtggcgcaatcttggcttactgcaacatccacctcccgagttcaagtgatttctcctgcctcagcctcccaagtagctgggactacaggcatgcgccaccacgcccagctaatttttgtgtttttagtagagatgggctttcaccatgctggccaggatggtctcgatctcttgacctcgtgatctgcccacctcggcctcccaaagtgctgggattacaggtgtgagccactgcgcctggcccgcatgtattacatttataattaaaaattcacaactcaatgtcaagtgtgaaccttgtgttgaccctgatttgagcaagcaataaaaagatatttttgagacatttagattatgaatttcacatttgatgatagttactattaattttgtgaggtgtgatattggcaatgtggttagatgacttcagagaaaaaggaaggtatagttaagcaagtatggcaacatctaataacttgggtctaggtgatgtgtatgggtttcattatactgtcctctttactgttgtatgtatttgaaaacattcatgacaaaaaaactttttaatcagttaaataaaccatgaagaacggttaaagaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:91807 -> Molecular function: GO:0004683 [calmodulin-dependent protein kinase activity] evidence: ISS
            GeneID:91807 -> Molecular function: GO:0004687 [myosin light chain kinase activity] evidence: ISS
            GeneID:91807 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
            GeneID:91807 -> Biological process: GO:0002528 [regulation of vascular permeability involved in acute inflammatory response] evidence: IMP
            GeneID:91807 -> Biological process: GO:0006468 [protein phosphorylation] evidence: ISS
            GeneID:91807 -> Biological process: GO:0045214 [sarcomere organization] evidence: ISS
            GeneID:91807 -> Biological process: GO:0048769 [sarcomerogenesis] evidence: ISS
            GeneID:91807 -> Biological process: GO:0055003 [cardiac myofibril assembly] evidence: ISS
            GeneID:91807 -> Biological process: GO:0060298 [positive regulation of sarcomere organization] evidence: ISS
            GeneID:91807 -> Biological process: GO:0071347 [cellular response to interleukin-1] evidence: IMP
            GeneID:91807 -> Cellular component: GO:0005737 [cytoplasm] evidence: ISS
            GeneID:91807 -> Cellular component: GO:0005829 [cytosol] evidence: ISS
            GeneID:91807 -> Cellular component: GO:0015629 [actin cytoskeleton] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_872299 -> EC 2.7.11.18

by @meso_cacase at DBCLS
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