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2024-04-26 01:04:06, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_174858 3326 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens adenylate kinase 5 (AK5), transcript variant 1, mRNA.
ACCESSION NM_174858
VERSION NM_174858.2 GI:320118914
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3326)
AUTHORS Solaroli,N., Panayiotou,C., Johansson,M. and Karlsson,A.
TITLE Identification of two active functional domains of human adenylate
kinase 5
JOURNAL FEBS Lett. 583 (17), 2872-2876 (2009)
PUBMED 19647735
REMARK GeneRIF: Data demonstrate that human adenylate kinase 5 has two
separate functional domains and that both have enzymatic activity.
REFERENCE 2 (bases 1 to 3326)
AUTHORS Van Rompay,A.R., Johansson,M. and Karlsson,A.
TITLE Identification of a novel human adenylate kinase. cDNA cloning,
expression analysis, chromosome localization and characterization
of the recombinant protein
JOURNAL Eur. J. Biochem. 261 (2), 509-517 (1999)
PUBMED 10215863
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AF445193.1, BC036666.1 and
AW665223.1.
On Jan 27, 2011 this sequence version replaced gi:28144896.
Summary: This gene encodes a member of the adenylate kinase family,
which is involved in regulating the adenine nucleotide composition
within a cell by catalyzing the reversible transfer of phosphate
groups among adenine nucleotides. This member is related to the
UMP/CMP kinase of several species. It is located in the cytosol and
expressed exclusively in brain. Alternatively spliced transcript
variants encoding distinct isoforms have been identified for this
gene. [provided by RefSeq, Jul 2008].
Transcript Variant: This variant (1) represents the shorter
transcript yet it encodes the longer protein (isoform 1).
##Evidence-Data-START##
Transcript exon combination :: AF445193.1, BC036666.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082, ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-2020 AF445193.1 1-2020
2021-3211 BC036666.1 1947-3137
3212-3326 AW665223.1 1-115 c
FEATURES Location/Qualifiers
source 1..3326
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p31"
gene 1..3326
/gene="AK5"
/gene_synonym="AK6"
/note="adenylate kinase 5"
/db_xref="GeneID:26289"
/db_xref="HGNC:365"
/db_xref="HPRD:10472"
/db_xref="MIM:608009"
exon 1..397
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 6
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:150974259"
variation 75
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:35260482"
variation 77
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="c"
/db_xref="dbSNP:2272161"
variation 83
/gene="AK5"
/gene_synonym="AK6"
/replace="g"
/replace="t"
/db_xref="dbSNP:34360007"
variation 164
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:75961421"
misc_feature 206..208
/gene="AK5"
/gene_synonym="AK6"
/note="upstream in-frame stop codon"
variation 242
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="g"
/db_xref="dbSNP:114518551"
variation 321
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:116049705"
CDS 338..2026
/gene="AK5"
/gene_synonym="AK6"
/EC_number="2.7.4.3"
/note="isoform 1 is encoded by transcript variant 1;
adenylate kinase 6; adenylate kinase isoenzyme 5; AK 5;
ATP-AMP transphosphorylase 5"
/codon_start=1
/product="adenylate kinase isoenzyme 5 isoform 1"
/protein_id="NP_777283.1"
/db_xref="GI:28144897"
/db_xref="CCDS:CCDS675.1"
/db_xref="GeneID:26289"
/db_xref="HGNC:365"
/db_xref="HPRD:10472"
/db_xref="MIM:608009"
/translation="
MNTNDAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF
"
misc_feature 734..1285
/gene="AK5"
/gene_synonym="AK6"
/note="adenylate kinase, isozyme 1 subfamily; Region:
aden_kin_iso1; TIGR01360"
/db_xref="CDD:130427"
misc_feature 737..1258
/gene="AK5"
/gene_synonym="AK6"
/note="Adenylate kinase (ADK) catalyzes the reversible
phosphoryl transfer from adenosine triphosphates (ATP) to
adenosine monophosphates (AMP) and to yield adenosine
diphosphates (ADP). This enzyme is required for the
biosynthesis of ADP and is essential for...; Region: ADK;
cd01428"
/db_xref="CDD:30189"
misc_feature order(824..826,839..841,914..916,989..994,998..1003,
1013..1015)
/gene="AK5"
/gene_synonym="AK6"
/note="AMP-binding site [chemical binding]; other site"
/db_xref="CDD:30189"
misc_feature order(839..841,989..991,1001..1003,1106..1108,1157..1159,
1169..1171)
/gene="AK5"
/gene_synonym="AK6"
/note="ATP-AMP (Ap5A)-binding site [chemical binding];
other site"
/db_xref="CDD:30189"
misc_feature 1457..2020
/gene="AK5"
/gene_synonym="AK6"
/note="adenylate kinase, isozyme 1 subfamily; Region:
aden_kin_iso1; TIGR01360"
/db_xref="CDD:130427"
misc_feature 1469..1987
/gene="AK5"
/gene_synonym="AK6"
/note="Adenylate kinase (ADK) catalyzes the reversible
phosphoryl transfer from adenosine triphosphates (ATP) to
adenosine monophosphates (AMP) and to yield adenosine
diphosphates (ADP). This enzyme is required for the
biosynthesis of ADP and is essential for...; Region: ADK;
cd01428"
/db_xref="CDD:30189"
misc_feature order(1556..1558,1571..1573,1640..1642,1718..1723,
1727..1732,1742..1744)
/gene="AK5"
/gene_synonym="AK6"
/note="AMP-binding site [chemical binding]; other site"
/db_xref="CDD:30189"
misc_feature order(1571..1573,1718..1720,1730..1732,1835..1837,
1886..1888,1898..1900)
/gene="AK5"
/gene_synonym="AK6"
/note="ATP-AMP (Ap5A)-binding site [chemical binding];
other site"
/db_xref="CDD:30189"
exon 398..584
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 431
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:377289573"
variation 503
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:185653281"
variation 506
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:370854870"
variation 511
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="t"
/db_xref="dbSNP:375338556"
variation 569
/gene="AK5"
/gene_synonym="AK6"
/replace="g"
/replace="t"
/db_xref="dbSNP:201693741"
exon 585..752
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 614
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:371926363"
variation 616
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:376603067"
variation 627
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:377402236"
variation 646
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:141811769"
variation 666
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:139371844"
variation 672
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="t"
/db_xref="dbSNP:142682163"
variation 682
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:61750801"
variation 685
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:2815311"
variation 697
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:147092224"
variation 706
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:114141042"
variation 720
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="c"
/db_xref="dbSNP:375637166"
exon 753..922
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 801
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:141828356"
variation 802
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:147715774"
variation 818
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:202109440"
variation 874
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:143289456"
variation 902
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:148313492"
variation 911
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:147728124"
exon 923..1036
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 931
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:145622294"
variation 946
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:1167206"
variation 964
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="c"
/db_xref="dbSNP:199993219"
variation 969
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:202122429"
exon 1037..1228
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 1116
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="c"
/db_xref="dbSNP:6697938"
variation 1125
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:368109019"
variation 1134
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:375971532"
variation 1138
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="t"
/db_xref="dbSNP:149285214"
variation 1159
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="c"
/db_xref="dbSNP:373956524"
exon 1229..1319
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 1233
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="t"
/db_xref="dbSNP:142574855"
variation 1237
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:140334353"
variation 1246
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:145653115"
variation 1302
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:141100989"
exon 1320..1396
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 1341
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:145823239"
variation 1349
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:145725699"
variation 1373
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:112387891"
exon 1397..1439
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 1403..1404
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="c"
/db_xref="dbSNP:34538335"
variation 1419
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:370095569"
exon 1440..1484
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
exon 1485..1648
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 1572
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:61746349"
variation 1582
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:200866780"
variation 1583
/gene="AK5"
/gene_synonym="AK6"
/replace="g"
/replace="t"
/db_xref="dbSNP:201908609"
variation 1585
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="c"
/db_xref="dbSNP:188562692"
variation 1615
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:141264115"
variation 1620
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="t"
/db_xref="dbSNP:143683857"
variation 1648
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="t"
/db_xref="dbSNP:371973784"
exon 1649..1765
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 1651
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:148262226"
variation 1652
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:61755974"
variation 1677
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:371556654"
variation 1693
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:199723351"
variation 1694
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:150764329"
variation 1702
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="c"
/db_xref="dbSNP:143509402"
variation 1707
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:375069994"
variation 1730
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:140295986"
variation 1731
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:2803140"
variation 1757
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:369967441"
exon 1766..1957
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
STS 1776..1913
/gene="AK5"
/gene_synonym="AK6"
/standard_name="D1S1862E"
/db_xref="UniSTS:72926"
variation 1804
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:151295675"
variation 1819
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="g"
/db_xref="dbSNP:139378577"
variation 1823
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:370891362"
variation 1842
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:373612539"
variation 1861
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:146562729"
variation 1868
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:367716253"
variation 1879
/gene="AK5"
/gene_synonym="AK6"
/replace="g"
/replace="t"
/db_xref="dbSNP:1801656"
variation 1886
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:144951885"
variation 1888
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:370947292"
variation 1891
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:374567822"
variation 1901
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="t"
/db_xref="dbSNP:202099336"
variation 1909
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:148897349"
variation 1934
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:201375489"
exon 1958..3325
/gene="AK5"
/gene_synonym="AK6"
/inference="alignment:Splign:1.39.8"
variation 1984
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:143678200"
variation 1997
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:377203431"
variation 2016..2020
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="tat"
/db_xref="dbSNP:79671213"
variation 2016
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:77198824"
variation 2017..2018
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="tat"
/db_xref="dbSNP:71756472"
variation 2019..2020
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="att"
/db_xref="dbSNP:72506825"
variation 2020..2021
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="aat"
/replace="t"
/db_xref="dbSNP:6485"
variation 2021..2022
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="att"
/db_xref="dbSNP:71823108"
variation 2021
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="t"
/db_xref="dbSNP:77417596"
variation 2023
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:61750802"
variation 2040..2043
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="tgtt"
/db_xref="dbSNP:200727498"
variation 2051
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="c"
/db_xref="dbSNP:373112277"
variation 2052
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:142470217"
variation 2158..2159
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="tgtt"
/db_xref="dbSNP:202043220"
variation 2237
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:151239663"
variation 2273
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:10873950"
variation 2278
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:113893032"
variation 2327
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:181213889"
variation 2330
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:74090653"
variation 2331
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:186460953"
variation 2415..2416
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="agtc"
/replace="cagt"
/db_xref="dbSNP:112935115"
variation 2416..2417
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="gtca"
/db_xref="dbSNP:373682778"
variation 2435
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="c"
/db_xref="dbSNP:140451977"
variation 2448
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:150417038"
variation 2466
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:191693728"
variation 2480..2481
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="cat"
/db_xref="dbSNP:112287024"
variation 2481..2482
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="cat"
/db_xref="dbSNP:370751498"
variation 2493..2494
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="tgtc"
/db_xref="dbSNP:200359662"
variation 2549..2550
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="ttga"
/db_xref="dbSNP:374195502"
variation 2598..2599
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="att"
/db_xref="dbSNP:377521979"
variation 2637
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:78679929"
variation 2645
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="g"
/db_xref="dbSNP:370618959"
variation 2659
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:12184282"
variation 2682..2687
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="tattat"
/db_xref="dbSNP:145212571"
variation 2692..2693
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="atta"
/replace="attattt"
/db_xref="dbSNP:373208507"
variation 2718
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:3767031"
variation 2719
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:112338588"
variation 2720..2721
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="att"
/db_xref="dbSNP:201307752"
variation 2720
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:3767030"
variation 2791
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:181577428"
variation 2870
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:74090654"
variation 2872..2873
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="tat"
/db_xref="dbSNP:3835546"
variation 2901
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="gtat"
/db_xref="dbSNP:200030950"
variation 2902..2905
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="aata"
/db_xref="dbSNP:3835545"
variation 2902
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="attt"
/db_xref="dbSNP:10577779"
variation 2905
/gene="AK5"
/gene_synonym="AK6"
/replace="g"
/replace="t"
/db_xref="dbSNP:113619910"
variation 2907
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:201281306"
variation 2956
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:141319214"
variation 2978
/gene="AK5"
/gene_synonym="AK6"
/replace="g"
/replace="t"
/db_xref="dbSNP:145435264"
variation 2991
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:77098319"
variation 3082..3083
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="t"
/db_xref="dbSNP:34108682"
variation 3106
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:116079431"
variation 3110
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="t"
/db_xref="dbSNP:116330920"
variation 3112
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:186075277"
variation 3125
/gene="AK5"
/gene_synonym="AK6"
/replace="g"
/replace="t"
/db_xref="dbSNP:4949811"
variation 3130
/gene="AK5"
/gene_synonym="AK6"
/replace="c"
/replace="t"
/db_xref="dbSNP:4949660"
variation 3141
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:75798281"
STS 3175..3293
/gene="AK5"
/gene_synonym="AK6"
/standard_name="SHGC-30349"
/db_xref="UniSTS:63095"
variation 3222
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:3509"
variation 3235
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:114513739"
variation 3268
/gene="AK5"
/gene_synonym="AK6"
/replace="a"
/replace="g"
/db_xref="dbSNP:190884445"
variation 3272
/gene="AK5"
/gene_synonym="AK6"
/replace=""
/replace="t"
/db_xref="dbSNP:370705588"
ORIGIN
gccacgctgtcctccctcctccgctccctgcgccccacccctggcggccgcgctgcctggcagcccgggaagccgcggcacagctgctcggcgcctgcagctccggctcgggggctggaaccgaagcgggggcggcgggagcgcggagaccacagcccccggggagaggcggagggggtccctggcctgggcggagaggctgagctgagtgcgcgtgagaaagagggctgcaccgctgctcggcgcggactctgccagccccagcttcagccccggctcaggtcgccgcagcccgggagcctccccgcttgcgccccaaggcacgcgcggcacagccatgaacaccaacgatgccaaggagtatctggcccggagggaaatccctcagctttttgagagccttttgaatggactgatgtgttctaagcccgaagatccagtagaatacttggaaagttgtttacaaaaagtaaaggaactgggtggctgtgacaaggtgaaatgggatacatttgtaagccaggaaaagaagaccttacctccactaaatggaggacagtcacggagatcctttctaagaaatgtaatgcctgaaaactcaaactttccatatcggcggtatgaccggctccctccaatccatcaattctccatagaaagtgacacggatctctctgagactgcagagttgattgaggagtatgaggtttttgatcctaccagacctcgaccaaaaatcattcttgttataggtggtccaggaagtggaaagggtactcagagtttgaaaattgcagaacgatatggattccaatacatttctgtgggagaattattaagaaagaagatccacagtaccagcagcaataggaaatggagtcttattgccaagataattacaactggagaattggccccacaggaaacaacaattacagagataaaacaaaaattgatgcaaatacctgatgaagagggcattgttattgatggatttccaagagatgttgcccaggctctatcttttgaggaccaaatctgtacccccgatttggtggtattcctggcttgtgctaatcagagactcaaagaaagattactgaagcgtgcagaacagcagggccgaccagacgacaatgtaaaagctacccaaaggagactaatgaacttcaagcagaatgctgctccattggttaaatacttccaggaaaaggggctcatcatgacatttgatgccgaccgcgatgaggatgaggtgttctatgacatcagcatggcagttgacaacaagttatttccaaacaaagaggctgcagcaggttcaagtgaccttgatccttcgatgatattggacactggagagatcattgatacaggatctgattatgaagatcagggtgatgaccagttaaatgtatttggagaggacactatgggaggtttcatggaagatttgagaaagtgtaaaattattttcataattggtggtcctggctctggcaaaggcacacagtgtgaaaagctggtggaaaaatatggatttacacatctctcaactggcgagctcctgcgtgaggaactggcatcagaatctgaaagaagcaaattgatcagagacattatggaacgtggagacctggtgccctcaggcatcgttttggagctcctgaaggaggccatggtggccagcctcggggacaccaggggcttcctgattgacggctatcctcgggaggtgaagcaaggggaagagttcggacgcaggattggagacccacagttggtgatctgtatggactgctcggcagacaccatgaccaaccgccttctccaaaggagccggagcagcctgcctgtggacgacaccaccaagaccatcgccaagcgcctagaagcctactaccgagcgtccatccccgtgatcgcctactacgagacaaaaacacagctacacaagataaatgcagagggaacaccagaggacgtttttcttcaactctgcacagctattgactctattttctgaaggcaaaaatgcatgtttgttagaatggaaacagaaaaacattaaaaagttcattccttaacacaatgtttcaagttaaaccttttgtgtcaccgcccccaccaaccaccacctcctaaatcctgacagcactgtttgcttcccagctagacctgtgtgagaggtgtctggaaatcatgcatggtgtatttgggactatatcaacctattctccacacttcagacaactgtctgcactcacggcacacacactttgtatcatgcaggccacactcagagctagtcagtacatgaacagtggtgcggtgccagtctgtgtccgttgtgatcacaggccttgctagaccctgatcatctggttctcctctcattaagcatccctaacccccagtcacaccttcctcttacatactgttccccaatggaggcccctggcataggggacagccctgggcatcttcctttggtgtctggctgttttgtcaactctcatccactggtggctcagagccataaggtgggttgattacacaatgccttgtacatgatatagaggcatcaagcaagtaaaatttgacagaaattttaaaatatgaagatgtatagctttcccaagatgatggtaaaacccaggttagtcatcagtaaccttctctattattattattttttagaaacttggaatactgtcgtcatggctaagagaacaaatctgataaattgtgtaacctagtctcttctctacatggtgatgcatttcagcaattataaattaatataaatgaccaaaagtaacttaaaagcatgagatatttgctatttcattcattgggcacatatcaaattataattttgattttaaatggtcacccatgtatttatttgttgccaagcaagtaaaaaaataccctaacaaacctgatgtgggtgggaggggcatgtcagtaagtggtgtgttcaatgtgtttgtttcatatgggccctttccaggagtttgcaaaccttgtcatacccatatgcaaaactgtgtttccttgcattaaaccagtgaagtttgggttctcttttgtgctatcaatcagttgtaaaatcagagctgcttatatattctactggaataactgcatcttccactcagtcactacaaaaaagcatagtttcagtttgcatgaatttttttttttttcttcaatggctgtgcagataaggatccatttctgggatagaattgtattttttaagtcatttttttttcttgaaatggatatgtacaaataaaataaatggaagacaggataaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:26289 -> Molecular function: GO:0004017 [adenylate kinase activity] evidence: IEA
GeneID:26289 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:26289 -> Molecular function: GO:0008603 [cAMP-dependent protein kinase regulator activity] evidence: IEA
GeneID:26289 -> Molecular function: GO:0019206 [nucleoside kinase activity] evidence: EXP
GeneID:26289 -> Biological process: GO:0006172 [ADP biosynthetic process] evidence: TAS
GeneID:26289 -> Biological process: GO:0006173 [dADP biosynthetic process] evidence: TAS
GeneID:26289 -> Biological process: GO:0007165 [signal transduction] evidence: IEA
GeneID:26289 -> Biological process: GO:0009220 [pyrimidine ribonucleotide biosynthetic process] evidence: TAS
GeneID:26289 -> Biological process: GO:0015949 [nucleobase-containing small molecule interconversion] evidence: TAS
GeneID:26289 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
GeneID:26289 -> Biological process: GO:0046034 [ATP metabolic process] evidence: IEA
GeneID:26289 -> Biological process: GO:0055086 [nucleobase-containing small molecule metabolic process] evidence: TAS
GeneID:26289 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:26289 -> Cellular component: GO:0005813 [centrosome] evidence: IDA
GeneID:26289 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_777283 -> EC 2.7.4.3
by
@meso_cacase at
DBCLS
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