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2024-04-19 14:07:16, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_153366 12356 bp mRNA linear PRI 15-JUN-2013
DEFINITION Homo sapiens sushi, von Willebrand factor type A, EGF and pentraxin
domain containing 1 (SVEP1), mRNA.
ACCESSION NM_153366 XM_928623 XM_941266
VERSION NM_153366.3 GI:148886653
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 12356)
AUTHORS Pasquale,L.R., Loomis,S.J., Aschard,H., Kang,J.H., Cornelis,M.C.,
Qi,L., Kraft,P. and Hu,F.B.
TITLE Exploring genome-wide - dietary heme iron intake interactions and
the risk of type 2 diabetes
JOURNAL Front Genet 4, 7 (2013)
PUBMED 23386860
REFERENCE 2 (bases 1 to 12356)
AUTHORS Sato-Nishiuchi,R., Nakano,I., Ozawa,A., Sato,Y., Takeichi,M.,
Kiyozumi,D., Yamazaki,K., Yasunaga,T., Futaki,S. and Sekiguchi,K.
TITLE Polydom/SVEP1 is a ligand for integrin alpha9beta1
JOURNAL J. Biol. Chem. 287 (30), 25615-25630 (2012)
PUBMED 22654117
REMARK GeneRIF: polydom is a hitherto unknown ligand for integrin
alpha9beta1 that functions as a physiological ligand in vivo.
REFERENCE 3 (bases 1 to 12356)
AUTHORS Imboden,M., Bouzigon,E., Curjuric,I., Ramasamy,A., Kumar,A.,
Hancock,D.B., Wilk,J.B., Vonk,J.M., Thun,G.A., Siroux,V., Nadif,R.,
Monier,F., Gonzalez,J.R., Wjst,M., Heinrich,J., Loehr,L.R.,
Franceschini,N., North,K.E., Altmuller,J., Koppelman,G.H.,
Guerra,S., Kronenberg,F., Lathrop,M., Moffatt,M.F., O'Connor,G.T.,
Strachan,D.P., Postma,D.S., London,S.J., Schindler,C.,
Kogevinas,M., Kauffmann,F., Jarvis,D.L., Demenais,F. and
Probst-Hensch,N.M.
TITLE Genome-wide association study of lung function decline in adults
with and without asthma
JOURNAL J. Allergy Clin. Immunol. 129 (5), 1218-1228 (2012)
PUBMED 22424883
REFERENCE 4 (bases 1 to 12356)
AUTHORS Taylan,A., Sari,I., Kozaci,D.L., Yildiz,Y., Bilge,S., Coker,I.,
Maltas,S., Gunay,N. and Akkoc,N.
TITLE Evaluation of various endothelial biomarkers in ankylosing
spondylitis
JOURNAL Clin. Rheumatol. 31 (1), 23-28 (2012)
PUBMED 21556780
REMARK GeneRIF: Increased UT-II, sTM, and vWF in ankylosing spondylitis
patient sera regardless of treatment and disease activity suggest
an increased tendency for atherosclerosis.
REFERENCE 5 (bases 1 to 12356)
AUTHORS Yashin,A.I., Wu,D., Arbeev,K.G. and Ukraintseva,S.V.
TITLE Joint influence of small-effect genetic variants on human longevity
JOURNAL Aging (Albany NY) 2 (9), 612-620 (2010)
PUBMED 20834067
REFERENCE 6 (bases 1 to 12356)
AUTHORS Tang,C.S., Sribudiani,Y., Miao,X.P., de Vries,A.R., Burzynski,G.,
So,M.T., Leon,Y.Y., Yip,B.H., Osinga,J., Hui,K.J., Verheij,J.B.,
Cherny,S.S., Tam,P.K., Sham,P.C., Hofstra,R.M. and
Garcia-Barcelo,M.M.
TITLE Fine mapping of the 9q31 Hirschsprung's disease locus
JOURNAL Hum. Genet. 127 (6), 675-683 (2010)
PUBMED 20361209
REMARK GeneRIF: Observational study of gene-disease association and
gene-gene interaction. (HuGE Navigator)
REFERENCE 7 (bases 1 to 12356)
AUTHORS Schwanzer-Pfeiffer,D., Rossmanith,E., Schildberger,A. and
Falkenhagen,D.
TITLE Characterization of SVEP1, KIAA, and SRPX2 in an in vitro cell
culture model of endotoxemia
JOURNAL Cell. Immunol. 263 (1), 65-70 (2010)
PUBMED 20236627
REMARK GeneRIF: acts as regulator of ICAM1 and E-selectin during
endotoxemia
REFERENCE 8 (bases 1 to 12356)
AUTHORS Ferreira,M.A., O'Donovan,M.C., Meng,Y.A., Jones,I.R.,
Ruderfer,D.M., Jones,L., Fan,J., Kirov,G., Perlis,R.H., Green,E.K.,
Smoller,J.W., Grozeva,D., Stone,J., Nikolov,I., Chambert,K.,
Hamshere,M.L., Nimgaonkar,V.L., Moskvina,V., Thase,M.E., Caesar,S.,
Sachs,G.S., Franklin,J., Gordon-Smith,K., Ardlie,K.G.,
Gabriel,S.B., Fraser,C., Blumenstiel,B., Defelice,M., Breen,G.,
Gill,M., Morris,D.W., Elkin,A., Muir,W.J., McGhee,K.A.,
Williamson,R., MacIntyre,D.J., MacLean,A.W., St,C.D., Robinson,M.,
Van Beck,M., Pereira,A.C., Kandaswamy,R., McQuillin,A.,
Collier,D.A., Bass,N.J., Young,A.H., Lawrence,J., Ferrier,I.N.,
Anjorin,A., Farmer,A., Curtis,D., Scolnick,E.M., McGuffin,P.,
Daly,M.J., Corvin,A.P., Holmans,P.A., Blackwood,D.H., Gurling,H.M.,
Owen,M.J., Purcell,S.M., Sklar,P. and Craddock,N.
CONSRTM Wellcome Trust Case Control Consortium
TITLE Collaborative genome-wide association analysis supports a role for
ANK3 and CACNA1C in bipolar disorder
JOURNAL Nat. Genet. 40 (9), 1056-1058 (2008)
PUBMED 18711365
REFERENCE 9 (bases 1 to 12356)
AUTHORS Shur,I., Socher,R., Hameiri,M., Fried,A. and Benayahu,D.
TITLE Molecular and cellular characterization of SEL-OB/SVEP1 in
osteogenic cells in vivo and in vitro
JOURNAL J. Cell. Physiol. 206 (2), 420-427 (2006)
PUBMED 16206243
REMARK GeneRIF: All together makes SEL-OB/SVEP1 an attractive marker for
studying the role of stromal osteogenic cells and their
interactions within the bone marrow microenvironment creating a
network that regulates the skeletal homeostasis.
REFERENCE 10 (bases 1 to 12356)
AUTHORS Gilges,D., Vinit,M.A., Callebaut,I., Coulombel,L., Cacheux,V.,
Romeo,P.H. and Vigon,I.
TITLE Polydom: a secreted protein with pentraxin, complement control
protein, epidermal growth factor and von Willebrand factor A
domains
JOURNAL Biochem. J. 352 (PT 1), 49-59 (2000)
PUBMED 11062057
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
BC030816.1, AY243503.1, CX165144.1, DR008048.1, BF368046.1,
DV080389.1, AK075200.1, AL832416.1, AL158158.14 and BX106110.1.
On Jun 16, 2007 this sequence version replaced gi:116256360.
##Evidence-Data-START##
RNAseq introns :: mixed/partial sample support ERS025081, ERS025082
[ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-2863 BC030816.1 1-2863
2864-3275 AY243503.1 2690-3101
3276-3741 CX165144.1 330-795
3742-4661 AY243503.1 3568-4487
4662-4906 DR008048.1 1-245 c
4907-5134 BF368046.1 147-374 c
5135-5658 AY243503.1 4970-5493
5659-6183 DV080389.1 83-607
6184-9912 AY243503.1 6019-9747
9913-10053 AK075200.1 368-508
10054-11311 AL832416.1 2541-3798
11312-12039 AL158158.14 129866-130593 c
12040-12356 BX106110.1 428-744
FEATURES Location/Qualifiers
source 1..12356
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9q32"
gene 1..12356
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="sushi, von Willebrand factor type A, EGF and
pentraxin domain containing 1"
/db_xref="GeneID:79987"
/db_xref="HGNC:15985"
/db_xref="MIM:611691"
exon 1..868
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
misc_feature 212..214
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="upstream in-frame stop codon"
CDS 338..11053
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="sushi, von Willebrand factor type A, EGF and
pentraxin domain-containing protein 1; selectin-like
protein; serologically defined breast cancer antigen
NY-BR-38; CCP module-containing protein 22; selectin-like
osteoblast-derived protein"
/codon_start=1
/product="sushi, von Willebrand factor type A, EGF and
pentraxin domain-containing protein 1 precursor"
/protein_id="NP_699197.3"
/db_xref="GI:148886654"
/db_xref="CCDS:CCDS48004.1"
/db_xref="GeneID:79987"
/db_xref="HGNC:15985"
/db_xref="MIM:611691"
/translation="
MWPRLAFCCWGLALVSGWATFQQMSPSRNFSFRLFPETAPGAPGSIPAPPAPGDEAAGSRVERLGQAFRRRVRLLRELSERLELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATRVAIVTFSSKNYVVPRVDYISTRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQAAQILLHARENSTKVVFLITDGYSNGGDPRPIAASLRDSGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHCSYLCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLEQQDSANVTWQIPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAIVYTATDLSGNQASCIFHIKVIDAEPPVIDWCRSPPPVQVSEKVHAASWDEPQFSDNSGAELVITRSHTQGDLFPQGETIVQYTATDPSGNNRTCDIHIVIKGSPCEIPFTPVNGDFICTPDNTGVNCTLTCLEGYDFTEGSTDKYYCAYEDGVWKPTYTTEWPDCAKKRFANHGFKSFEMFYKAARCDDTDLMKKFSEAFETTLGKMVPSFCSDAEDIDCRLEENLTKKYCLEYNYDYENGFAIGPGGWGAANRLDYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWENQQRLLQTLETITNKLKRTLNKDPMYSFQLASEILIADSNSLETKKASPFCRPGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGTYQPKFGSRSCLSCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTFWMKSSDDMNYGTPISYAVDNGSDNTLLLTDYNGWVLYVNGREKITNCPSVNDGRWHHIAITWTSANGIWKVYIDGKLSDGGAGLSVGLPIPGGGALVLGQEQDKKGEGFSPAESFVGSISQLNLWDYVLSPQQVKSLATSCPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKRRTGF
"
sig_peptide 338..388
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
mat_peptide 389..11050
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/product="Sushi, von Willebrand factor type A, EGF and
pentraxin domain-containing protein 1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q4LDE5.3)"
misc_feature 602..1069
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Von Willebrand factor type A (vWA) domain was
originally found in the blood coagulation protein von
Willebrand factor (vWF). Typically, the vWA domain is made
up of approximately 200 amino acid residues folded into a
classic a/b para-rossmann type of...; Region:
vWFA_subfamily_ECM; cd01450"
/db_xref="CDD:29223"
misc_feature order(602..604,608..610,614..616,836..838,923..925)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="metal ion-dependent adhesion site (MIDAS); other
site"
/db_xref="CDD:29223"
misc_feature order(608..616,620..622,836..838)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="integrin-collagen binding site; other site"
/db_xref="CDD:29223"
misc_feature order(650..652,905..907,911..913,992..994,1067..1069)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="integrin inhibitor binding pocket; other site"
/db_xref="CDD:29223"
misc_feature order(698..700,743..748,800..805)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="putative vWF-collagen binding site; other site"
/db_xref="CDD:29223"
misc_feature order(725..730,734..736,848..850,857..859,869..874)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="glycoprotein Ib (GpIb) binding site [polypeptide
binding]; other site"
/db_xref="CDD:29223"
misc_feature 1265..1417
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="GCC2 and GCC3; Region: GCC2_GCC3; pfam07699"
/db_xref="CDD:148998"
misc_feature 1469..1639
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(1499..1501,1556..1558)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 1649..1819
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(1679..1681,1736..1738)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 1871..1990
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature 1925..1927
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 2015..2263
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="HYR domain; Region: HYR; pfam02494"
/db_xref="CDD:111397"
misc_feature 2264..2503
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="HYR domain; Region: HYR; pfam02494"
/db_xref="CDD:111397"
misc_feature 2996..3019
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q4LDE5.3);
Region: O-glycosylated at one site"
misc_feature 3350..3493
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="GCC2 and GCC3; Region: GCC2_GCC3; pfam07699"
/db_xref="CDD:148998"
misc_feature 3512..3655
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="GCC2 and GCC3; Region: GCC2_GCC3; pfam07699"
/db_xref="CDD:148998"
misc_feature 3674..3796
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="GCC2 and GCC3; Region: GCC2_GCC3; pfam07699"
/db_xref="CDD:148998"
misc_feature 3923..4024
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Calcium-binding EGF-like domain, present in a large
number of membrane-bound and extracellular (mostly animal)
proteins. Many of these proteins require calcium for their
biological function and calcium-binding sites have been
found to be located at the...; Region: EGF_CA; cd00054"
/db_xref="CDD:28936"
misc_feature order(3923..3925,3965..3967)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:28936"
misc_feature 4028..4138
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Calcium-binding EGF-like domain, present in a large
number of membrane-bound and extracellular (mostly animal)
proteins. Many of these proteins require calcium for their
biological function and calcium-binding sites have been
found to be located at the...; Region: EGF_CA; cd00054"
/db_xref="CDD:28936"
misc_feature order(4028..4030,4037..4039,4079..4081)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:28936"
misc_feature 4142..4252
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Calcium-binding EGF-like domain, present in a large
number of membrane-bound and extracellular (mostly animal)
proteins. Many of these proteins require calcium for their
biological function and calcium-binding sites have been
found to be located at the...; Region: EGF_CA; cd00054"
/db_xref="CDD:28936"
misc_feature order(4142..4144,4151..4153,4193..4195)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:28936"
misc_feature 4256..4363
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Calcium-binding EGF-like domain, present in a large
number of membrane-bound and extracellular (mostly animal)
proteins. Many of these proteins require calcium for their
biological function and calcium-binding sites have been
found to be located at the...; Region: EGF_CA; cd00054"
/db_xref="CDD:28936"
misc_feature order(4256..4258,4265..4267,4307..4309)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:28936"
misc_feature 4370..4480
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Calcium-binding EGF-like domain, present in a large
number of membrane-bound and extracellular (mostly animal)
proteins. Many of these proteins require calcium for their
biological function and calcium-binding sites have been
found to be located at the...; Region: EGF_CA; cd00054"
/db_xref="CDD:28936"
misc_feature order(4370..4372,4379..4381,4421..4423)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:28936"
misc_feature 4484..4594
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Calcium-binding EGF-like domain, present in a large
number of membrane-bound and extracellular (mostly animal)
proteins. Many of these proteins require calcium for their
biological function and calcium-binding sites have been
found to be located at the...; Region: EGF_CA; cd00054"
/db_xref="CDD:28936"
misc_feature order(4484..4486,4493..4495,4535..4537)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:28936"
misc_feature 4607..5203
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Laminin G domain; Laminin G-like domains are
usually Ca++ mediated receptors that can have binding
sites for steroids, beta1 integrins, heparin, sulfatides,
fibulin-1, and alpha-dystroglycans. Proteins that contain
LamG domains serve a variety of...; Region: LamG; cl00102"
/db_xref="CDD:206838"
misc_feature order(4772..4774,5003..5005,5009..5011,5030..5032,
5039..5041)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="calcium mediated ligand binding site; other site"
/db_xref="CDD:29068"
misc_feature order(4889..4891,4940..4942,5054..5056,5201..5203)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="intermolecular salt bridges; other site"
/db_xref="CDD:29068"
misc_feature 5255..5395
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(5255..5257,5312..5314)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 5405..5566
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(5435..5437,5486..5488)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 5570..5674
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Calcium-binding EGF-like domain, present in a large
number of membrane-bound and extracellular (mostly animal)
proteins. Many of these proteins require calcium for their
biological function and calcium-binding sites have been
found to be located at the...; Region: EGF_CA; cd00054"
/db_xref="CDD:28936"
misc_feature order(5570..5572,5579..5581,5624..5626)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:28936"
misc_feature 5702..6388
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="secreted complement-binding protein; Provisional;
Region: PHA02927"
/db_xref="CDD:165238"
misc_feature 5702..5866
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(5732..5734,5783..5785)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 5876..6040
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(5906..5908,5957..5959)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 6050..6211
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(6080..6082,6131..6133)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 6224..6385
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(6254..6256,6305..6307)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 6398..6574
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature 6479..6481
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 6584..6745
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(6614..6616,6674..6676)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 6773..6934
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(6803..6805,6854..6856)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 6947..7117
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(6977..6979,7031..7033)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 7127..7291
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(7157..7159,7208..7210)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 7304..7468
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(7331..7333,7385..7387)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 7478..7627
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(7508..7510,7562..7564)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature <7715..7819
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature 7736..7738
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 7829..8647
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="secreted complement-binding protein; Provisional;
Region: PHA02927"
/db_xref="CDD:165238"
misc_feature 7829..7990
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(7859..7861,7910..7912)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 8003..8161
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(8033..8035,8084..8086)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature <8345..8476
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature 8393..8395
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 8471..9169
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="secreted complement-binding protein; Provisional;
Region: PHA02927"
/db_xref="CDD:165238"
misc_feature 8486..8650
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(8516..8518,8567..8569)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 8660..8824
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(8690..8692,8741..8743)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 8834..8998
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(8864..8866,8915..8917)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 8870..8878
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q4LDE5.3);
Region: Cell attachment site (Potential)"
misc_feature 8993..9688
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="secreted complement-binding protein; Provisional;
Region: PHA02927"
/db_xref="CDD:165238"
misc_feature 9008..9172
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature 9089..9091
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 9356..9517
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(9383..9385,9434..9436)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 9527..9691
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature 9608..9610
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 9701..9865
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(9731..9733,9782..9784)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 9878..10027
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature 9959..9961
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 10058..10222
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(10088..10090,10139..10141)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 10232..10396
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(10262..10264,10313..10315)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 10406..10573
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(10439..10441,10490..10492)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
misc_feature 10583..10744
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="Complement control protein (CCP) modules (aka short
consensus repeats SCRs or SUSHI repeats) have been
identified in several proteins of the complement system;
Region: CCP; cd00033"
/db_xref="CDD:153056"
misc_feature order(10613..10615,10664..10666)
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/note="receptor-ligand interactions; other site"
/db_xref="CDD:153056"
exon 869..1124
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 1125..1301
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 1302..1460
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
variation 1332
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/replace="c"
/replace="g"
/db_xref="dbSNP:3818764"
exon 1461..1640
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 1641..1820
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 1821..2018
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
variation 1906
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/replace="a"
/replace="g"
/db_xref="dbSNP:3737156"
exon 2019..2137
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 2138..2267
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 2268..2375
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 2376..2507
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 2508..2702
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 2703..2824
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 2825..2936
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 2937..3101
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 3102..3335
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 3336..3497
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 3498..3659
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 3660..3821
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 3822..3913
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 3914..4010
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 4011..4124
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 4125..4238
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 4239..4440
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 4441..4598
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
variation 4583
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/replace="a"
/replace="c"
/db_xref="dbSNP:1889323"
exon 4599..4800
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 4801..4976
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 4977..5101
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 5102..5225
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 5226..5396
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 5397..5570
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 5571..5690
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 5691..5867
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 5868..5952
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 5953..6144
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 6145..6312
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 6313..6985
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 6986..9777
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
variation 8156
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/replace="a"
/replace="g"
/db_xref="dbSNP:3802433"
variation 8977
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/replace="g"
/replace="t"
/db_xref="dbSNP:79933952"
exon 9778..10003
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
variation 9818
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/replace="a"
/replace="t"
/db_xref="dbSNP:3739451"
exon 10004..10159
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 10160..10223
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 10224..10397
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 10398..10574
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 10575..10745
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 10746..10841
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 10842..10937
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 10938..11031
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
exon 11032..12344
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/inference="alignment:Splign:1.39.8"
STS 11104..11310
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/standard_name="D9S2010"
/db_xref="UniSTS:44828"
STS 11144..11311
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/standard_name="RH91731"
/db_xref="UniSTS:91448"
STS 11145..11311
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/standard_name="SHGC-132375"
/db_xref="UniSTS:170802"
STS 11160..11309
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/standard_name="SHGC-24282"
/db_xref="UniSTS:15417"
polyA_signal 11286..11291
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
polyA_site 11310
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
polyA_signal 11390..11395
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
polyA_site 11416
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
variation 11948
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/replace="a"
/replace="c"
/db_xref="dbSNP:3739453"
variation 12034
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/replace="a"
/replace="c"
/db_xref="dbSNP:1046653"
variation 12039
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/replace="c"
/replace="t"
/db_xref="dbSNP:3180638"
STS 12109..12234
/gene="SVEP1"
/gene_synonym="C9orf13; CCP22; POLYDOM; SEL-OB; SELOB"
/standard_name="RH12799"
/db_xref="UniSTS:53940"
ORIGIN
agggagagaaggagggaagcgggagatttttcttgactgccccctttccttcaaacattttataggcttcagggagagagaggaggaggagagagggaagaaaaaaagaggagagcgagaggggtagagagcgcgcgccgttccctccggagttcccgagctgctgaggagtctggattgtgtctgtccccagtgtcagatgaaagggcgctgaggctcttggccgctgccccgcgcccagctccgcgcacgcccctctgcgagtccggccgcccagcgcctcttcccgcccgagccgccgcctgcgctccggggcagccgctctgtctccagcgcgatgtggcctcgcctggccttttgttgctggggtctggcgctcgtttcgggctgggcgacctttcagcagatgtccccgtcgcgcaatttcagcttccgcctcttccccgagaccgcgcccggggcccccgggagtatccccgcgccgcccgctcctggcgacgaagcggcggggagcagagtggagcggctgggccaggcgttccggcgacgcgtgcggctgctgcgggagctcagcgagcgcctggagcttgtcttcctggtggatgattcgtccagcgtgggcgaagtcaacttccgcagcgagctcatgttcgtccgcaagctgctgtccgacttccccgtggtgcccacggccacgcgcgtggccatcgtgaccttctcgtccaagaactacgtggtgccgcgcgtcgattacatctccacccgccgcgcgcgccagcacaagtgcgcgctgctcctccaagagatccctgccatctcctaccgaggtggcggcacctacaccaagggcgccttccagcaagccgcgcaaattcttcttcatgctagagaaaactcaacaaaagttgtatttctcatcactgatggatattccaatgggggagaccctagaccaattgcagcgtcactgcgagattcaggagtggagatcttcacttttggcatatggcaagggaacattcgagagctgaatgacatggcttccaccccaaaggaggagcactgttacctgctacacagttttgaagaatttgaggctttagctcgccgggcattgcatgaagatctaccttctgggagttttattcaagatgatatggtccactgctcatatctttgtgatgaaggcaaggactgctgtgaccgaatgggaagctgcaaatgtgggacacacacaggccattttgagtgcatctgtgaaaaggggtattacgggaaaggtctgcagtatgaatgcacagcttgcccatcggggacatacaaacctgaaggctcaccaggaggaatcagcagttgcattccatgtcctgatgaaaatcacacctctccacctggaagcacatcccctgaagactgtgtctgcagagagggatacagggcatctggccagacctgtgaacttgtccactgccctgccctgaagcctcccgaaaatggttactttatccaaaacacttgcaacaaccacttcaatgcagcctgtggggtccgatgtcaccctggatttgatcttgtgggaagcagcatcatcttatgtctacccaatggtttgtggtccggttcagagagctactgcagagtaagaacatgtcctcatctccgccagccgaaacatggccacatcagctgttctacaagggaaatgttatataagacaacatgtttggttgcctgtgatgaagggtacagactagaaggcagtgataagcttacttgtcaaggaaacagccagtgggatgggccagaaccccggtgtgtggagcgccactgttccacctttcagatgcccaaagatgtcatcatatccccccacaactgtggcaagcagccagccaaatttgggacgatctgctatgtaagttgccgccaagggttcattttatctggagtcaaagaaatgctgagatgtaccacttctggaaaatggaatgtcggagttcaggcagctgtgtgtaaagacgtggaggctcctcaaatcaactgtcctaaggacatagaggctaagactctggaacagcaagattctgccaatgttacctggcagattccaacagctaaagacaactctggtgaaaaggtgtcagtccacgttcatccagctttcaccccaccttaccttttcccaattggagatgttgctatcgtatacacggcaactgacctatccggcaaccaggccagctgcattttccatatcaaggttattgatgcagaaccacctgtcatagactggtgcagatctccacctcccgtccaggtctcggagaaggtacatgccgcaagctgggatgagcctcagttctcagacaactcaggggctgaattggtcattaccagaagtcatacacaaggagaccttttccctcaaggggagactatagtacagtatacagccactgacccctcaggcaataacaggacatgtgatatccatattgtcataaaaggttctccctgtgaaattccattcacacctgtaaatggggattttatatgcactccagataatactggagtcaactgtacattaacttgcttggagggctatgatttcacagaagggtctactgacaagtattattgtgcttatgaagatggcgtctggaaaccaacatataccactgaatggccagactgtgccaaaaaacgttttgcaaaccacgggttcaagtcctttgagatgttctacaaagcagctcgttgtgatgacacagatctgatgaagaagttttctgaagcatttgagacgaccctgggaaaaatggtcccatcattttgtagtgatgcagaggacattgactgcagactggaggagaacctgaccaaaaaatattgcctagaatataattatgactatgaaaatggctttgcaattggaccaggtggctggggtgcagctaataggctggattactcttacgatgacttcctggacactgtgcaagaaacagccacaagcatcggcaatgccaagtcctcacggattaaaagaagtgccccattatctgactataaaattaagttaatttttaacatcacagctagtgtgccattacccgatgaaagaaatgatacccttgaatgggaaaatcagcaacgactccttcagacattggaaactatcacaaataaactgaaaaggactctcaacaaagaccccatgtattcctttcagcttgcatcagaaatacttatagccgacagcaattcattagaaacaaaaaaggcttcccccttctgcagaccaggctcagtgctgagagggcgtatgtgtgtcaattgccctttgggaacctattataatctggaacatttcacctgtgaaagctgccggatcggatcctatcaagatgaagaagggcaacttgagtgcaagctttgcccctctgggatgtacacggaatatatccattcaagaaacatctctgattgtaaagctcagtgtaaacaaggcacctactcatacagtggacttgagacttgtgaatcgtgtccactgggcacttatcagccaaaatttggttcccggagctgcctctcgtgtccagaaaacacctcaactgtgaaaagaggagccgtgaacatttctgcatgtggagttccttgtccagaaggaaaattctcgcgttctgggttaatgccctgtcacccatgtcctcgtgactattaccaacctaatgcagggaaggccttctgcctggcctgtcccttttatggaactaccccattcgctggttccagatccatcacagaatgttcaagttttagttcaactttctcagcggcagaggaaagtgtggtgccccctgcctctcttggacatattaaaaagaggcatgaaatcagcagtcaggttttccatgaatgcttctttaacccttgccacaatagtggaacctgccagcaacttgggcgtggttatgtttgtctctgtccacttggatatacaggcttaaagtgtgaaacagacatcgatgagtgcagcccactgccttgcctcaacaatggagtttgtaaagacctagttggggaattcatttgtgagtgcccatcaggttacacaggtcagcggtgtgaagaaaatataaatgagtgtagctccagtccttgtttaaataaaggaatctgtgttgatggtgtggctggctatcgttgcacatgtgtgaaaggatttgtaggcctgcattgtgaaacagaagtcaatgaatgccagtcaaacccatgcttaaataatgcagtctgtgaagaccaggttgggggattcttgtgcaaatgcccacctggatttttgggtacccgatgtggaaagaacgtcgatgagtgtctcagtcagccatgcaaaaatggagctacctgtaaagacggtgccaatagcttcagatgcctgtgtgcagctggcttcacaggatcacactgtgaattgaacatcaatgaatgtcagtctaatccatgtagaaatcaggccacctgtgtggatgaattaaattcatacagttgtaaatgtcagccaggattttcaggcaaaaggtgtgaaacagaacagtctacaggctttaacctggattttgaagtttctggcatctatggatatgtcatgctagatggcatgctcccatctctccatgctctaacctgtaccttctggatgaaatcctctgacgacatgaactatggaacaccaatctcctatgcagttgataacggcagcgacaataccttgctcctgactgattataacggctgggttctttatgtgaatggcagggaaaagataacaaactgtccctcggtgaatgatggcagatggcatcatattgcaatcacttggacaagtgccaatggcatctggaaagtctatatcgatgggaaattatctgacggtggtgctggcctctctgttggtttgcccatacctggtggtggtgcgttagttctggggc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//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:79987 -> Molecular function: GO:0003682 [chromatin binding] evidence: IEA
GeneID:79987 -> Molecular function: GO:0005509 [calcium ion binding] evidence: IEA
GeneID:79987 -> Biological process: GO:0007155 [cell adhesion] evidence: IEA
GeneID:79987 -> Cellular component: GO:0005576 [extracellular region] evidence: IEA
GeneID:79987 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA
GeneID:79987 -> Cellular component: GO:0016020 [membrane] evidence: IEA
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