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2024-03-29 08:17:21, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_145725               7793 bp    mRNA    linear   PRI 15-JUL-2013
DEFINITION  Homo sapiens TNF receptor-associated factor 3 (TRAF3), transcript
            variant 1, mRNA.
ACCESSION   NM_145725
VERSION     NM_145725.2  GI:313661479
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7793)
  AUTHORS   Cai,X., Du,J., Liu,Y., Xia,W., Liu,J., Zou,M., Wang,Y., Wang,M.,
            Su,H. and Xu,D.
  TITLE     Identification and characterization of receptor-interacting protein
            2 as a TNFR-associated factor 3 binding partner
  JOURNAL   Gene 517 (2), 205-211 (2013)
   PUBMED   23333941
  REMARK    GeneRIF: In an attempt to explore TRAF3 binding partners that may
            be involved in TRAF3-regulated signaling, a yeast two-hybrid screen
            of a human spleen cDNA library was undertaken. RIP2 was identified
            as a TRAF3 binding partner.
REFERENCE   2  (bases 1 to 7793)
  AUTHORS   Wolf,K. and Fields,K.A.
  TITLE     Chlamydia pneumoniae impairs the innate immune response in infected
            epithelial cells by targeting TRAF3
  JOURNAL   J. Immunol. 190 (4), 1695-1701 (2013)
   PUBMED   23303668
  REMARK    GeneRIF: Levels of TRAF3 degradation correlate with number of cells
            infected with Chlamydia pneumoniae, because more TRAF3 is detected
            at a lower multiplicity of C. pneumoniae infection.
REFERENCE   3  (bases 1 to 7793)
  AUTHORS   Shen,J., Qiao,Y.Q., Ran,Z.H. and Wang,T.R.
  TITLE     Up-regulation and pre-activation of TRAF3 and TRAF5 in inflammatory
            bowel disease
  JOURNAL   Int J Med Sci 10 (2), 156-163 (2013)
   PUBMED   23329887
  REMARK    GeneRIF: TRAF3 and TRAF5 are overexpressed in inflammatory bowel
            disease. Although the endoscopic appearance can be normal, TRAF3
            and TRAF5 pre-activation can be detected in non-inflamed colonic
            segments
REFERENCE   4  (bases 1 to 7793)
  AUTHORS   Belgnaoui,S.M., Paz,S., Samuel,S., Goulet,M.L., Sun,Q., Kikkert,M.,
            Iwai,K., Dikic,I., Hiscott,J. and Lin,R.
  TITLE     Linear ubiquitination of NEMO negatively regulates the interferon
            antiviral response through disruption of the MAVS-TRAF3 complex
  JOURNAL   Cell Host Microbe 12 (2), 211-222 (2012)
   PUBMED   22901541
  REMARK    GeneRIF: Ubiquitination of NEMO negatively regulates the interferon
            antiviral response through disruption of the MAVS-TRAF3 complex.
REFERENCE   5  (bases 1 to 7793)
  AUTHORS   van Zuylen,W.J., Doyon,P., Clement,J.F., Khan,K.A.,
            D'Ambrosio,L.M., Do,F., St-Amant-Verret,M., Wissanji,T., Emery,G.,
            Gingras,A.C., Meloche,S. and Servant,M.J.
  TITLE     Proteomic profiling of the TRAF3 interactome network reveals a new
            role for the ER-to-Golgi transport compartments in innate immunity
  JOURNAL   PLoS Pathog. 8 (7), E1002747 (2012)
   PUBMED   22792062
  REMARK    GeneRIF: model proposed where dsDNA and dsRNA sensing induces the
            formation of membrane-bound compartments originating from the
            Golgi, which mediate the dynamic association of TRAF3 with MAVS
            leading to an optimal induction of innate immune responses
REFERENCE   6  (bases 1 to 7793)
  AUTHORS   Hsu,H., Shu,H.B., Pan,M.G. and Goeddel,D.V.
  TITLE     TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF
            receptor 1 signal transduction pathways
  JOURNAL   Cell 84 (2), 299-308 (1996)
   PUBMED   8565075
REFERENCE   7  (bases 1 to 7793)
  AUTHORS   Cheng,G., Cleary,A.M., Ye,Z.S., Hong,D.I., Lederman,S. and
            Baltimore,D.
  TITLE     Involvement of CRAF1, a relative of TRAF, in CD40 signaling
  JOURNAL   Science 267 (5203), 1494-1498 (1995)
   PUBMED   7533327
REFERENCE   8  (bases 1 to 7793)
  AUTHORS   Mosialos,G., Birkenbach,M., Yalamanchili,R., VanArsdale,T., Ware,C.
            and Kieff,E.
  TITLE     The Epstein-Barr virus transforming protein LMP1 engages signaling
            proteins for the tumor necrosis factor receptor family
  JOURNAL   Cell 80 (3), 389-399 (1995)
   PUBMED   7859281
REFERENCE   9  (bases 1 to 7793)
  AUTHORS   Sato,T., Irie,S. and Reed,J.C.
  TITLE     A novel member of the TRAF family of putative signal transducing
            proteins binds to the cytosolic domain of CD40
  JOURNAL   FEBS Lett. 358 (2), 113-118 (1995)
   PUBMED   7530216
REFERENCE   10 (bases 1 to 7793)
  AUTHORS   Hu,H.M., O'Rourke,K., Boguski,M.S. and Dixit,V.M.
  TITLE     A novel RING finger protein interacts with the cytoplasmic domain
            of CD40
  JOURNAL   J. Biol. Chem. 269 (48), 30069-30072 (1994)
   PUBMED   7527023
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from U21092.1, AL132801.5,
            BX247977.1, AL117209.7 and BQ000015.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Dec 7, 2010 this sequence version replaced gi:22027617.
            
            Summary: The protein encoded by this gene is a member of the TNF
            receptor associated factor (TRAF) protein family. TRAF proteins
            associate with, and mediate the signal transduction from, members
            of the TNF receptor (TNFR) superfamily. This protein participates
            in the signal transduction of CD40, a TNFR family member important
            for the activation of the immune response. This protein is found to
            be a critical component of the lymphotoxin-beta receptor (LTbetaR)
            signaling complex, which induces NF-kappaB activation and cell
            death initiated by LTbeta ligation. Epstein-Barr virus encoded
            latent infection membrane protein-1 (LMP1) can interact with this
            and several other members of the TRAF family, which may be
            essential for the oncogenic effects of LMP1. Several alternatively
            spliced transcript variants encoding three distinct isoforms have
            been reported. [provided by RefSeq, Dec 2010].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1). Variants 1 and 3
            both encode the same isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX247977.1 [ECO:0000332]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-81                U21092.1           4-84
            82-106              AL132801.5         21810-21834         c
            107-154             U21092.1           110-157
            155-2537            BX247977.1         1-2383
            2538-7771           AL117209.7         122476-127709
            7772-7793           BQ000015.1         1-22                c
FEATURES             Location/Qualifiers
     source          1..7793
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q32.32"
     gene            1..7793
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /note="TNF receptor-associated factor 3"
                     /db_xref="GeneID:7187"
                     /db_xref="HGNC:12033"
                     /db_xref="HPRD:03539"
                     /db_xref="MIM:601896"
     exon            1..197
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       131
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1051750"
     exon            198..336
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       212
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:79869075"
     variation       242
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140896812"
     misc_feature    267..269
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /note="upstream in-frame stop codon"
     variation       327
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:186237761"
     exon            337..598
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       346
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370752725"
     variation       348
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:190521973"
     CDS             354..2060
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /note="isoform 1 is encoded by transcript variant 1; CD40
                     binding protein; CD40 receptor associated factor 1; CD40
                     associated protein 1; LMP1-associated protein 1"
                     /codon_start=1
                     /product="TNF receptor-associated factor 3 isoform 1"
                     /protein_id="NP_663777.1"
                     /db_xref="GI:22027618"
                     /db_xref="CCDS:CCDS9975.1"
                     /db_xref="GeneID:7187"
                     /db_xref="HGNC:12033"
                     /db_xref="HPRD:03539"
                     /db_xref="MIM:601896"
                     /translation="
MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDLPDP
"
     misc_feature    507..638
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /note="RING-finger (Really Interesting New Gene) domain, a
                     specialized type of Zn-finger of 40 to 60 residues that
                     binds two atoms of zinc; defined by the 'cross-brace'
                     motif C-X2-C-X(9-39)-C-X(1-3)-
                     H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved
                     in...; Region: RING; cd00162"
                     /db_xref="CDD:29102"
     misc_feature    order(510..512,519..521,555..557,561..563,570..572,
                     579..581,615..617,624..626)
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /note="cross-brace motif; other site"
                     /db_xref="CDD:29102"
     misc_feature    759..929
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /note="TRAF-type zinc finger; Region: zf-TRAF; pfam02176"
                     /db_xref="CDD:190233"
     misc_feature    942..1106
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /note="TRAF-type zinc finger; Region: zf-TRAF; pfam02176"
                     /db_xref="CDD:190233"
     misc_feature    1485..2042
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /note="Tumor Necrosis Factor Receptor (TNFR)-Associated
                     Factor (TRAF) family, TRAF3 subfamily, TRAF domain; TRAF
                     molecules serve as adapter proteins that link TNFRs and
                     downstream kinase cascades resulting in the activation of
                     transcription factors and the...; Region: MATH_TRAF3;
                     cd03777"
                     /db_xref="CDD:58108"
     misc_feature    order(1548..1550,1557..1559,1581..1583,1587..1589,
                     1608..1610,1614..1616,1698..1703,1794..1796,1803..1805,
                     1854..1856)
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:58108"
     misc_feature    order(1722..1724,1728..1730,1740..1742,1746..1748,
                     1773..1775,1887..1889,1896..1898,1911..1913,1941..1952)
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /note="TNFR binding site; other site"
                     /db_xref="CDD:58108"
     variation       362
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377427517"
     variation       387
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139127242"
     variation       389
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199639339"
     variation       400..401
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:376342002"
     variation       406
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145456077"
     variation       427
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370955205"
     variation       428
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1051749"
     variation       429
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375545964"
     variation       469
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147686384"
     variation       491
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201415483"
     variation       538
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183443558"
     variation       542
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142350527"
     exon            599..650
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       599
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146435455"
     variation       620
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147871145"
     variation       623
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:149018928"
     exon            651..755
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       694
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12896018"
     variation       700
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372370114"
     variation       705
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143813189"
     variation       730
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:377142394"
     variation       739
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1131877"
     exon            756..923
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       802
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141920055"
     variation       836
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374166578"
     variation       860
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145367471"
     variation       915
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:137916856"
     exon            924..1004
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       935
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368161114"
     variation       938
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186117694"
     variation       939
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142439625"
     variation       979
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199989168"
     variation       981
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145947234"
     variation       1000
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139458877"
     exon            1005..1079
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       1059
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368804411"
     variation       1071
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200118821"
     exon            1080..1172
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       1083
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:149327017"
     variation       1127
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144578195"
     variation       1159
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369640883"
     variation       1160
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201211273"
     exon            1173..1313
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       1191..1192
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:35228820"
     variation       1307
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182757817"
     exon            1314..1488
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       1315
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148461790"
     variation       1322
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1131876"
     variation       1340
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372134660"
     variation       1376
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145200267"
     variation       1413
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369697250"
     variation       1445
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201374351"
     variation       1452
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147610812"
     variation       1463
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1051743"
     variation       1465
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144719184"
     exon            1489..7776
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /inference="alignment:Splign:1.39.8"
     variation       1538
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376141594"
     variation       1547
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151258452"
     variation       1553
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370697221"
     variation       1577
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140423891"
     variation       1580
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150483724"
     variation       1592
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111762207"
     variation       1607
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201486992"
     variation       1622
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377168511"
     variation       1649
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145391228"
     variation       1667
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:3742448"
     STS             1697..2587
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /standard_name="TRAF3_v555"
                     /db_xref="UniSTS:277842"
     variation       1706
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1051742"
     variation       1736
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141356642"
     variation       1760
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200974693"
     variation       1769
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150561735"
     variation       1838
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199868254"
     variation       1841
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145126372"
     variation       1862
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138943371"
     variation       1867
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186844617"
     variation       1880
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202084269"
     variation       1895
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374255469"
     variation       1931
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:142501447"
     variation       1980
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372089179"
     variation       1987
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144637377"
     variation       1997
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370725073"
     variation       2042
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148195281"
     variation       2051
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377148855"
     variation       2077
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369453811"
     STS             2098..2229
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /standard_name="RH69049"
                     /db_xref="UniSTS:33196"
     variation       2116
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373244439"
     variation       2165
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191258518"
     variation       2178
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377143104"
     variation       2190
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139584485"
     STS             2214..2451
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /standard_name="G15867"
                     /db_xref="UniSTS:12048"
     variation       2410..2411
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace=""
                     /replace="ac"
                     /db_xref="dbSNP:371921986"
     variation       2411..2412
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace=""
                     /replace="ac"
                     /db_xref="dbSNP:142806500"
     variation       2411
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201568881"
     variation       2514
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184183944"
     variation       2943
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188857207"
     variation       2970..2971
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:57120368"
     variation       3004
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142745057"
     variation       3016
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192894065"
     variation       3037
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:147370186"
     variation       3041
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:185305434"
     variation       3084
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139583976"
     variation       3127
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144980713"
     variation       3129
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:80216614"
     variation       3172
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:190155467"
     variation       3290
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374592471"
     variation       3341
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75249707"
     variation       3358..3359
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace=""
                     /replace="atct"
                     /db_xref="dbSNP:375424663"
     variation       3373
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:72704737"
     variation       3572
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373295670"
     variation       3577
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372051148"
     variation       3634
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:112261683"
     variation       3672
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376429109"
     variation       3679..3680
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace=""
                     /replace="ca"
                     /db_xref="dbSNP:201700309"
     variation       3813
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182212093"
     variation       3846
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148584503"
     variation       3914
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367719643"
     variation       3984
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142988351"
     variation       3997..3998
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:34474027"
     variation       4013
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151084914"
     variation       4016
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186127559"
     variation       4065
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:141331668"
     variation       4099
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:117897999"
     variation       4106
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:117475076"
     variation       4165
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188198787"
     variation       4259
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:114392221"
     variation       4322
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376100146"
     variation       4339
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:145120246"
     variation       4381
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:117653635"
     variation       4382
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:117106738"
     variation       4408
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7152158"
     variation       4502
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:34578787"
     variation       4560
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116178840"
     variation       4610
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374825187"
     variation       4616
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:180688846"
     variation       4649
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11160707"
     variation       4823
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11552465"
     variation       5000
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185075993"
     variation       5026
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146802843"
     variation       5039
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191356380"
     variation       5076
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372945156"
     variation       5101
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183222973"
     variation       5133
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:45517731"
     variation       5206
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376995306"
     variation       5269
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:45585743"
     variation       5333
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:78630751"
     variation       5366
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201281332"
     variation       5385
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:186841343"
     variation       5413
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:80197834"
     variation       5445
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191683954"
     variation       5453
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183394545"
     variation       5479
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74082969"
     variation       5528
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:187691773"
     variation       5533
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:4906271"
     variation       5642
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375292813"
     variation       5755
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35360806"
     variation       5857
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368940960"
     variation       5970
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4906272"
     variation       6024
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375381789"
     variation       6068
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138179996"
     variation       6091
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:117406867"
     variation       6096
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:149530934"
     variation       6128
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143203754"
     variation       6133
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191019034"
     variation       6178
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369985542"
     variation       6197
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11620870"
     variation       6221
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182443319"
     variation       6234
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186731083"
     variation       6264
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:192760623"
     variation       6325
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:117597898"
     variation       6333
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138947290"
     variation       6346
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142791534"
     variation       6419
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147406100"
     variation       6423
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:4906273"
     variation       6463
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:373563762"
     variation       6499
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138001318"
     variation       6517
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376776135"
     variation       6540
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370848396"
     variation       6571
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:45478597"
     variation       6577
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:188439936"
     variation       6713
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374197709"
     variation       6726
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:193031191"
     variation       6729
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369332741"
     variation       6767
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:4900558"
     variation       6807
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377603736"
     variation       6838
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184726526"
     variation       6971
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370260743"
     variation       7005
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143573604"
     variation       7006
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374968722"
     variation       7071
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377708288"
     variation       7195
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150503115"
     variation       7260
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10133111"
     variation       7264
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1046299"
     variation       7288
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:45528941"
     variation       7293
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11552464"
     variation       7401
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:79926472"
     variation       7410
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368377660"
     variation       7416
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:117858701"
     STS             7638..7746
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /standard_name="WI-13969"
                     /db_xref="UniSTS:60858"
     variation       7659
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115804335"
     variation       7681
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:78211216"
     polyA_signal    7753..7758
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
     polyA_site      7776
                     /gene="TRAF3"
                     /gene_synonym="CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1"
ORIGIN      
gggagcgcggcgcggccgccgcgtgcgcgagccggggttgcagcccagccgggactttccagccggcggcagccgcggcggccgccggctcttccccgccccccgccatggggcagcccggggagcagaacgctgcggaccgcggcggaggacgcgcccggcgcccctgagccggccgagcggcgacggaccgcgagatgaggaaaatgaggcccaaagaagtgatgccacttggttaaggtcccagagcaggtcagaatcagacctaggatcagaaacctggctcctggctcctggctccctactcttctaaggatcgctgtcctgacagaagagaactcctctttcctaaaatggagtcgagtaaaaagatggactctcctggcgcgctgcagactaacccgccgctaaagctgcacactgaccgcagtgctgggacgccagtttttgtccctgaacaaggaggttacaaggaaaagtttgtgaagaccgtggaggacaagtacaagtgtgagaagtgccacctggtgctgtgcagcccgaagcagaccgagtgtgggcaccgcttctgcgagagctgcatggcggccctgctgagctcttcaagtccaaaatgtacagcgtgtcaagagagcatcgttaaagataaggtgtttaaggataattgctgcaagagagaaattctggctcttcagatctattgtcggaatgaaagcagaggttgtgcagagcagttaatgctgggacatctgctggtgcatttaaaaaatgattgccattttgaagaacttccatgtgtgcgtcctgactgcaaagaaaaggtcttgaggaaagacctgcgagaccacgtggagaaggcgtgtaaataccgggaagccacatgcagccactgcaagagtcaggttccgatgatcgcgctgcagaaacacgaagacaccgactgtccctgcgtggtggtgtcctgccctcacaagtgcagcgtccagactctcctgaggagcgagttgagtgcacacttgtcagagtgtgtcaatgcccccagcacctgtagttttaagcgctatggctgcgtttttcaggggacaaaccagcagatcaaggcccacgaggccagctccgccgtgcagcacgtcaacctgctgaaggagtggagcaactcgctcgaaaagaaggtttccttgttgcagaatgaaagtgtagaaaaaaacaagagcatacaaagtttgcacaatcagatatgtagctttgaaattgaaattgagagacaaaaggaaatgcttcgaaataatgaatccaaaatccttcatttacagcgagtgatagacagccaagcagagaaactgaaggagcttgacaaggagatccggcccttccggcagaactgggaggaagcagacagcatgaagagcagcgtggagtccctccagaaccgcgtgaccgagctggagagcgtggacaagagcgcggggcaagtggctcggaacacaggcctgctggagtcccagctgagccggcatgaccagatgctgagtgtgcacgacatccgcctagccgacatggacctgcgcttccaggtcctggagaccgccagctacaatggagtgctcatctggaagattcgcgactacaagcggcggaagcaggaggccgtcatggggaagaccctgtccctttacagccagcctttctacactggttactttggctataagatgtgtgccagggtctacctgaacggggacgggatggggaaggggacgcacttgtcgctgttttttgtcatcatgcgtggagaatatgatgccctgcttccttggccgtttaagcagaaagtgacactcatgctgatggatcaggggtcctctcgacgtcatttgggagatgcattcaagcccgaccccaacagcagcagcttcaagaagcccactggagagatgaatatcgcctctggctgcccagtctttgtggcccaaactgttctagaaaatgggacatatattaaagatgatacaatttttattaaagtcatagtggatacttcggatctgcccgatccctgataagtagctggggaggtggatttagcagaaggcaactcctctgggggatttgaaccggtctgtcttcactgaggtcctcgcgctcagaaaaggaccttgtgagacggaggaagcggcagaaggcggacgcgtgccggcgggaggagccacgcgtgagcacacctgacacgttttataatagactagccacacttcactctgaagaattatttatccttcaacaagataaatattgctgtcagagaaggttttcattttcatttttaaagatctagttaattaaggtggaaaacatatatgctaaacaaaagaaacatgatttttcttccttaaacttgaacaccaaaaaaacacacacacacacacacgtggggatagctggacatgtcagcatgttaagtaaaaggagaatttatgaaatagtaatgcaattctgatatcttctttctaaaattcaagagtgcaattttgtttcaaatacagtatattgtctatttttaaggcctcatctggtctctgttttaataatttgtttgtcagaagaccctgaagtatatacctaggtcttttttttgaaagtctctaaattcagaatcattttttaatttaaagttctacaaataattgttactgcaaacattttattttaaaacgttgatagactgatatttcttggaagaaaatataaaatatcaaacactggttatcacttgtgataggaaagagaatattcaacctgttgttatttctcgttagaaatgtaaaccttcaaatatctgtcgtagttaatgacacgacttcacaattctgaacggagcctcgctcatggatgctgtgcatcattttcagatttataattgttttcaccctaaaatagggcatccgttgaactttggagttctaaacaaaatcctgtaggtgtttggattctgccccatgtgttcggacgagctctctgttgctgacagcaccggccttcggtctccatgtcaggggtgggcgggtgactgctgagggaggcccgcaggtgtgtttctccatcccgtcatcttgctgcatgccgtcaacggtctccgaaagcaacgttgtgcgtagagctggtggcatacggcccacgtgccttagatgggacatgctgcttctccaccctgggtttgcattgagcatcattctagaaagtgctagtttaaccagacttttctctccaccactagatctttgtctctacaagggccctcagacacctctgcacctgctgaggggaagccaggctccaccgtcggcttctggagcctccgctgcttaattaccacagattccaaatctctaggccccacgagtgagccgcctggtccaagtacggcctggtcccaccctgagggaggcaggtgtggaacagaagccgagcctctccgtgtccccaccggggccgtgggcacccccacagcccgaagcagaaccctctgagcattccagagaccgctgctcgggggcctgcccaggctgaccaacgggcgctcctgaccaccaccctggcgggaagggtggccacggggcccgtcgtcccagcctgtgcctgcccagatggcattttctcaactcactgtttactgtctctcagtgtccaactgtgattagaagcctggagcctgccccctgcaccccttttgctatgcaccacgcttcatggtgctcttaccactgatgggtgctacacgcgacgggtgcttcttaggcaaaaccaatgtgtgcgaactgtcacacctgtgccactcgcccacaagccgcgcccacaattggccagctgggccgtgcacgtcagactgcctgcctcggctctccccgtggccgcgcggggacagcttggtgggtgcccggtggcccacctgtctctggtgctgccatctgtcctgggtgtgccttcgccccagtgcctgctggaagtgccctccgtcgcacccctgtgccctgagctcccgtgaggggcccgccgcgccctttcgcggtcgaagcgttccgttgttcttatctgcctttcctttccccgctctcctgggattactttgggggaatgagtatccttggttctgccctgtgagggagtcgtgtgtccctgctcataaaggaaggacttcctgcagaagctgcggaaaactactgttccctcgaaggtgtcccccacctgaggcctgtcccctacctgccctcaggtagttttcctgaggccaggggttaacaacagggacatccctgcaacttccccttcacaaaatgtataatattagatgaaggatatgcaacatcttggtctagtaagaaccgtttcctcccctctgggttgaagtcctggtgtggcccccagaagcagcagtgcgtgtcactgggacgtctccagtagcccttcccaggcagacgctcctggcgggacgccatggggcccacctgagggtcccacagacgtaacctgagtgacaggagtccttgaggatgggatggcctatgtcacacactttgtccttgaacctgagtgatgggggtccttgaggatgggatggcctgtgtcacgcgctttgtctttgtgtttggttgtatcggggtctctgttctgagtgtgtcttcctctcatgtactcaacacagtgggcagcagcctgggacggcgtcccctctcccggcggcgggcaagccttgcgctgctccaccctcggcctgggcaccctcacttggcgctggccacctgggccagcctggggccatggtctctctgcagctgaggcccagtggccccttgggcagtgatcggccctccccgcatcacagggccctggcagcaagcgggaaatgggggcgcacactgtgtgcttgggggtgctgcttgtttaccacacatgaccagactcccagcaggacagagctgctcagtactttacagaaaccaactgagtcgtttgtgcatgaattaagccggtctgcttccccgtcaccttcgtaacaaaacaacgtcccctctcccctcgcctcgagcagtttcttcaggacaccgtggctcgggctgctccctgctgccaggcacgctggttggctggcctgggcccggctcacgtgaagggcactggctcttgtgaccacactgagccacgtgcaagccgcagccgggcctggaagcctgaccctctggttctagggcttgtcccgcggagcctgcagagctagacgttggggtgtgtccgtgatgatatgggggccaggctgggagtagggcctttctagcagggttgggtggctcagtgagggtgtggaagtgggggacccacggggcctggctttgggactagacatgccagccccagctgggctggagggagcctgagtgagccccgacatacgctgggcctttcagctcgccgtgctctggtgacacacaggcggccaggttgggatttgtgtcaattctaggagccatcaagcatgaatgtggttctgtctcctgagcgcaagcctcgccggacccctgggcgaaggcctggacttgcagatgtgtgttccctgtgcgggtggacagagggggcccttatgacccacattgcagccccattccaccaccccttcctccccagagcagtctctgccgagggacagcacctgtgtcccttcgatgccacaacagccagttgaacaggggagccctttgctcaggcagcttctcctgcctctccctcctttctccttccctgccccatccccgtgcccttcttggcctgtggcgctggggagccatggtgtggcatactggggctcctgctccttgggccacttcctcagcccgggccccacaggcccaccacctgccagggctcccactgcactggctgtggcaggaggcttccccatgaccccgtgtggcccagctcggtgaggatgcagttctaggcacagcccctgggacagccagctgcctcccagaccacgtcagcctgctccagggtcctcagtcaccctgggccaggggccacgtgtcccatggatgtcgaccatgccaacgtcacattccagcaccccttttgcttgatggcgtctggtggtagtcagcatggtggacccacatcctacagccagaggtgatgttggacaaaggaaggggagtctggatgggtccttaaacgaccattctgtccgcagcggggtcattccttgtcagcccaagggagggccggggagtacactgatcccaacagctgggctgacacctcctttctcccctgcacggggaggattggcctgaggaccgtcaccctgtgcacagccccagtagggtggcagtgccactgtctccttgggccgttgcaggattgggcgggtgcagactccccttgcgggccccttgctcaatccccggccctcccagactcctccctctactgggggtaatttgtgtgtcagaagggctctggcagagctgtaaaatactgttttttaaaaattttagtccagatctttacttattagactgcagaaggagagctagggagagtgggggaagcccccttgcttttgtatctgtgaggtgaatgagggtctgtcacccaaatctacttctcagcccatgaccatagttctgttttccgtttgcaaatctcagtagctctgttttctccaaagtagaatgtgcgcaccggggtcctagccaggcgaggtcagtgtcggcaggctacctggtcattattgctgcctcgtccaggctgatgctgatggtcacaggcacggtggcatcagggagccgggccagcaggcggcgtgaggcggggccagcagctcactgcaagggcattttccacctgatcctggtgtgccccacatgcggtggcagggcagacgtgtgaagcctcggccgtctcggggctggcaggtgtgcgggtgaggaggccccggtggccaagcagagcctgcgtttcatttctcctgctgcactgtgtctagtctgtcttgtgaactctcaccgtgaaaagaggctagaagtccaggatcgctgtaccgctcctgtaattaggtgatgactggatttgacaacttagtcccctcagacaagtaagataccctccaacagcaaattcaatgacttaattggaaaacacacaagctggcatgatgtccggtgatttctgtaagaaatgcctgtaggagaaggtctgtgaagtgtggagggcagtgtcgacgctgcacagcatctgcagattcgcagcctcttctctgccggtgcctctgttcggttctgttacccaaaaacaaagaccaaagaaggccaatctctcatttgaccctgtctttttaatctgcctgttttaaaagttgcgtctgtagtagccgcttgctgtgaagacacatcttgacagtccaagtgattttgtgaccagtgatttgggtcctgttttccgctcttctaagaaaaaacaaaaagaccgtgagttattgcccagcaataatcatgttgttactgtgagttagcaacatgcctgacttcctgatagcattactgttttctagttttgtttattgtatattatgtgtggttttatttggtatttatttgtgttttgaggtcttgcaatgtttttgtgtttctgatgctaataactaaagtttgtaagactgtagaatgcaaaactcggagatgctaaactgtcttattagaggaaaataaatctgattatggagtctcaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:7187 -> Molecular function: GO:0004842 [ubiquitin-protein ligase activity] evidence: TAS
            GeneID:7187 -> Molecular function: GO:0004871 [signal transducer activity] evidence: TAS
            GeneID:7187 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:7187 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
            GeneID:7187 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IEA
            GeneID:7187 -> Molecular function: GO:0031625 [ubiquitin protein ligase binding] evidence: IPI
            GeneID:7187 -> Molecular function: GO:0031996 [thioesterase binding] evidence: IPI
            GeneID:7187 -> Biological process: GO:0001817 [regulation of cytokine production] evidence: ISS
            GeneID:7187 -> Biological process: GO:0002224 [toll-like receptor signaling pathway] evidence: ISS
            GeneID:7187 -> Biological process: GO:0002224 [toll-like receptor signaling pathway] evidence: TAS
            GeneID:7187 -> Biological process: GO:0002756 [MyD88-independent toll-like receptor signaling pathway] evidence: TAS
            GeneID:7187 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
            GeneID:7187 -> Biological process: GO:0006917 [induction of apoptosis] evidence: TAS
            GeneID:7187 -> Biological process: GO:0007165 [signal transduction] evidence: TAS
            GeneID:7187 -> Biological process: GO:0008063 [Toll signaling pathway] evidence: IEA
            GeneID:7187 -> Biological process: GO:0030162 [regulation of proteolysis] evidence: IMP
            GeneID:7187 -> Biological process: GO:0032088 [negative regulation of NF-kappaB transcription factor activity] evidence: IMP
            GeneID:7187 -> Biological process: GO:0032480 [negative regulation of type I interferon production] evidence: TAS
            GeneID:7187 -> Biological process: GO:0032648 [regulation of interferon-beta production] evidence: ISS
            GeneID:7187 -> Biological process: GO:0033209 [tumor necrosis factor-mediated signaling pathway] evidence: IMP
            GeneID:7187 -> Biological process: GO:0034138 [toll-like receptor 3 signaling pathway] evidence: TAS
            GeneID:7187 -> Biological process: GO:0034142 [toll-like receptor 4 signaling pathway] evidence: TAS
            GeneID:7187 -> Biological process: GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] evidence: TAS
            GeneID:7187 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
            GeneID:7187 -> Biological process: GO:0050688 [regulation of defense response to virus] evidence: ISS
            GeneID:7187 -> Cellular component: GO:0005739 [mitochondrion] evidence: IEA
            GeneID:7187 -> Cellular component: GO:0005768 [endosome] evidence: IEA
            GeneID:7187 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:7187 -> Cellular component: GO:0009898 [internal side of plasma membrane] evidence: ISS
            GeneID:7187 -> Cellular component: GO:0035631 [CD40 receptor complex] evidence: ISS

by @meso_cacase at DBCLS
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