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2020-10-26 19:30:26, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_130445               5398 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens collagen, type XVIII, alpha 1 (COL18A1), transcript
            variant 2, mRNA.
ACCESSION   NM_130445
VERSION     NM_130445.2  GI:110611232
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5398)
  AUTHORS   Li,M., Liu,F., Sun,P., Gao,Y., Chen,H., Liu,H., Wang,M., Chen,J.
            and Zhao,Y.
  TITLE     Correlations between serum levels of vascular endothelial growth
            factor and endostatin with clinical pathological characteristics of
            patients with gastrointestinal cancers
  JOURNAL   Hepatogastroenterology 59 (118), 1865-1868 (2012)
   PUBMED   22819906
  REMARK    GeneRIF: Report pre/postoperative endostatin levels in surgically
            treated gastrointestinal cancers.
REFERENCE   2  (bases 1 to 5398)
  AUTHORS   Sunshine,S.B., Dallabrida,S.M., Durand,E., Ismail,N.S., Bazinet,L.,
            Birsner,A.E., Sohn,R., Ikeda,S., Pu,W.T., Kulke,M.H.,
            Javaherian,K., Zurakowski,D., Folkman,J.M. and Rupnick,M.
  TITLE     Endostatin lowers blood pressure via nitric oxide and prevents
            hypertension associated with VEGF inhibition
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 109 (28), 11306-11311 (2012)
   PUBMED   22733742
  REMARK    GeneRIF: Endostatin lowers blood pressure via nitric oxide and
            prevents hypertension associated with VEGF inhibition
REFERENCE   3  (bases 1 to 5398)
  AUTHORS   Melville SA, Buros J, Parrado AR, Vardarajan B, Logue MW, Shen L,
            Risacher SL, Kim S, Jun G, DeCarli C, Lunetta KL, Baldwin CT,
            Saykin AJ and Farrer LA.
  CONSRTM   Alzheimer's Disease Neuroimaging Initiative
  TITLE     Multiple loci influencing hippocampal degeneration identified by
            genome scan
  JOURNAL   Ann. Neurol. 72 (1), 65-75 (2012)
   PUBMED   22745009
REFERENCE   4  (bases 1 to 5398)
  AUTHORS   Chen,Y., Liang,B., Zhao,Y.J., Wang,S.C., Fan,Y.B. and Wu,G.P.
  TITLE     Transcription expression and clinical significance of vascular
            endothelial growth factor mRNA and endostatin mRNA in pleural
            effusions of patients with lung cancer
  JOURNAL   Diagn. Cytopathol. 40 (4), 287-291 (2012)
   PUBMED   22431315
  REMARK    GeneRIF: The detection of VEGF mRNA and endostatin mRNA appears to
            be suitable for distinguishing carcinoma cells from reactive
            mesothelial cells in pleural effusions, they could be useful to
            diagnose the pleural micrometastasis.
REFERENCE   5  (bases 1 to 5398)
  AUTHORS   Wu,X., Wu,J., Xin,Z., Wang,H., Zhu,X., Pan,L., Li,Z., Li,H. and
            Liu,Y.
  TITLE     A 3' UTR SNP in COL18A1 is associated with susceptibility to HBV
            related hepatocellular carcinoma in Chinese: three independent
            case-control studies
  JOURNAL   PLoS ONE 7 (3), E33855 (2012)
   PUBMED   22461898
  REMARK    GeneRIF: Findings indicate that COL18A1 rs7499 may contribute to
            the risk of Hepatocellular carcinoma (HCC) in Han Chinese.
REFERENCE   6  (bases 1 to 5398)
  AUTHORS   Ding,Y.H., Javaherian,K., Lo,K.M., Chopra,R., Boehm,T.,
            Lanciotti,J., Harris,B.A., Li,Y., Shapiro,R., Hohenester,E.,
            Timpl,R., Folkman,J. and Wiley,D.C.
  TITLE     Zinc-dependent dimers observed in crystals of human endostatin
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 95 (18), 10443-10448 (1998)
   PUBMED   9724722
REFERENCE   7  (bases 1 to 5398)
  AUTHORS   Saarela,J., Ylikarppa,R., Rehn,M., Purmonen,S. and Pihlajaniemi,T.
  TITLE     Complete primary structure of two variant forms of human type XVIII
            collagen and tissue-specific differences in the expression of the
            corresponding transcripts
  JOURNAL   Matrix Biol. 16 (6), 319-328 (1998)
   PUBMED   9503365
REFERENCE   8  (bases 1 to 5398)
  AUTHORS   Sertie,A.L., Quimby,M., Moreira,E.S., Murray,J., Zatz,M.,
            Antonarakis,S.E. and Passos-Bueno,M.R.
  TITLE     A gene which causes severe ocular alterations and occipital
            encephalocele (Knobloch syndrome) is mapped to 21q22.3
  JOURNAL   Hum. Mol. Genet. 5 (6), 843-847 (1996)
   PUBMED   8776601
REFERENCE   9  (bases 1 to 5398)
  AUTHORS   Oh,S.P., Kamagata,Y., Muragaki,Y., Timmons,S., Ooshima,A. and
            Olsen,B.R.
  TITLE     Isolation and sequencing of cDNAs for proteins with multiple
            domains of Gly-Xaa-Yaa repeats identify a distinct family of
            collagenous proteins
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 91 (10), 4229-4233 (1994)
   PUBMED   8183893
REFERENCE   10 (bases 1 to 5398)
  AUTHORS   Oh,S.P., Warman,M.L., Seldin,M.F., Cheng,S.D., Knoll,J.H.,
            Timmons,S. and Olsen,B.R.
  TITLE     Cloning of cDNA and genomic DNA encoding human type XVIII collagen
            and localization of the alpha 1(XVIII) collagen gene to mouse
            chromosome 10 and human chromosome 21
  JOURNAL   Genomics 19 (3), 494-499 (1994)
   PUBMED   8188291
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CN389577.1, BC063833.1 and
            AF018082.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Jul 20, 2006 this sequence version replaced gi:18765747.
            
            Summary: This gene encodes the alpha chain of type XVIII collagen.
            This collagen is one of the multiplexins, extracellular matrix
            proteins that contain multiple triple-helix domains (collagenous
            domains) interrupted by non-collagenous domains. The
            proteolytically produced C-terminal fragment of type XVIII collagen
            is endostatin, a potent antiangiogenic protein. Mutations in this
            gene are associated with Knobloch syndrome. The main features of
            this syndrome involve retinal abnormalities, so type XVIII collagen
            may play an important role in retinal structure and in neural tube
            closure. Alternatively spliced transcript variants encoding
            different isoforms have been found for this gene. [provided by
            RefSeq, Sep 2008].
            
            Transcript Variant: This variant (2) is generated from a more
            distal promoter. It has an alternate 5' UTR and 5' CDS, as compared
            to variant 3. The resulting isoform (2) has a shorter and different
            N-terminus, as compared to isoform 3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF018082.1, BC063833.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025083 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-343               CN389577.1         46-388
            344-3486            BC063833.1         330-3472
            3487-5398           AF018082.1         3497-5408
FEATURES             Location/Qualifiers
     source          1..5398
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.3"
     gene            1..5398
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="collagen, type XVIII, alpha 1"
                     /db_xref="GeneID:80781"
                     /db_xref="HGNC:2195"
                     /db_xref="MIM:120328"
     exon            1..60
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     CDS             50..4060
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; endostatin; collagen alpha-1(XVIII) chain;
                     antiangiogenic agent; multi-functional protein MFP"
                     /codon_start=1
                     /product="collagen alpha-1(XVIII) chain isoform 2
                     precursor"
                     /protein_id="NP_569712.2"
                     /db_xref="GI:110611233"
                     /db_xref="CCDS:CCDS42971.1"
                     /db_xref="GeneID:80781"
                     /db_xref="HGNC:2195"
                     /db_xref="MIM:120328"
                     /translation="
MAPRCPWPWPRRRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK
"
     sig_peptide     50..148
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     mat_peptide     149..4057
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /product="collagen alpha-1(XVIII) chain isoform 2"
     misc_feature    248..736
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="Laminin G domain; Laminin G-like domains are
                     usually Ca++ mediated receptors that can have binding
                     sites for steroids, beta1 integrins, heparin, sulfatides,
                     fibulin-1, and alpha-dystroglycans. Proteins that contain
                     LamG domains serve a variety of...; Region: LamG; cl00102"
                     /db_xref="CDD:206838"
     misc_feature    <2003..2128
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="Collagen triple helix repeat (20 copies); Region:
                     Collagen; pfam01391"
                     /db_xref="CDD:189968"
     misc_feature    3527..4039
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="Endostatin-like domain; the angiogenesis inhibitor
                     endostatin is a C-terminal fragment of collagen XV/XVIII,
                     a proteoglycan/collagen found in vessel walls and basement
                     membranes; this domain has a compact globular fold similar
                     to that of C-type lectins; Region: Endostatin-like;
                     cd00247"
                     /db_xref="CDD:29322"
     misc_feature    order(3620..3622,3647..3649,3665..3667,3692..3697,
                     3704..3706,3890..3895,3923..3925)
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:29322"
     exon            61..155
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     exon            156..700
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       167
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375719577"
     variation       175
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115800039"
     variation       199
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:190083327"
     variation       205
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373105258"
     variation       215
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375009748"
     variation       225
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200842530"
     variation       235
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372731688"
     variation       236
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377002382"
     variation       266
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370054491"
     variation       275
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374084790"
     variation       290
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:76658745"
     variation       291
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371058906"
     variation       337
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149578781"
     variation       344
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199918230"
     variation       345
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375588763"
     variation       346
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368228266"
     variation       359
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112855834"
     variation       364
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201508976"
     variation       385
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61735014"
     variation       390
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373861758"
     variation       393
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367715239"
     variation       401
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200702024"
     variation       416
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376829205"
     variation       441
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368606628"
     variation       442
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372142063"
     variation       469
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:17004775"
     variation       499
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367852328"
     variation       500
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201833726"
     variation       509
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375242667"
     variation       516
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369275624"
     variation       517
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372556095"
     variation       523
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377547341"
     variation       537
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376036984"
     variation       545
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144281842"
     variation       559
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76754353"
     variation       627
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2236453"
     variation       647
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370834739"
     variation       649
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374980607"
     variation       652
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17004776"
     variation       653
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373735265"
     variation       661
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373748503"
     variation       662
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201116208"
     variation       673
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76148908"
     variation       675
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376944366"
     exon            701..787
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       703
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369219412"
     variation       709
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189093550"
     variation       716
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:60162212"
     variation       720
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200168928"
     variation       725
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375001641"
     variation       726
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201095161"
     variation       740
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202012055"
     variation       742
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149772252"
     variation       763
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369721525"
     exon            788..847
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       792
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200073359"
     variation       808
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374330522"
     variation       816
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368233273"
     variation       820
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371736290"
     variation       824
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376722572"
     variation       825
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:62000965"
     exon            848..977
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       850
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145912433"
     variation       852
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375414087"
     variation       853
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368376035"
     variation       877
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2230686"
     variation       885
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375411877"
     variation       886
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2230687"
     variation       890
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:192075600"
     variation       895
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2230688"
     variation       921
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201652671"
     variation       922
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183924183"
     variation       923
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138471288"
     variation       936
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372308402"
     variation       946
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376715250"
     variation       960
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200230216"
     variation       961
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141548934"
     variation       964
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:17338853"
     variation       969
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200882031"
     variation       974
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369289615"
     variation       975
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372726135"
     exon            978..1054
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1011
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372492704"
     variation       1019
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375058072"
     variation       1046
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367882523"
     exon            1055..1270
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1057
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372133935"
     variation       1058
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76547444"
     variation       1061
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369413748"
     variation       1092
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372859456"
     variation       1100
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370176315"
     variation       1106
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369114408"
     variation       1107
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373030953"
     variation       1121
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:62000458"
     variation       1145
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377028409"
     variation       1155
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371330320"
     variation       1186
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374344376"
     variation       1192
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2230689"
     variation       1243
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370965213"
     variation       1252
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375400196"
     variation       1261
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367951949"
     variation       1264
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370283993"
     variation       1270
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368902481"
     exon            1271..1297
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1273
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:13046486"
     variation       1274
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200553372"
     variation       1297
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185296216"
     exon            1298..1360
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1303
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368594049"
     variation       1306
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:183085141"
     variation       1310
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375265466"
     variation       1315
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113540632"
     variation       1324
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1131100"
     variation       1339
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1131101"
     variation       1341
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201414473"
     variation       1354
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1131102"
     exon            1361..1447
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1372
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201380467"
     variation       1391
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373670175"
     variation       1436
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376357877"
     variation       1439
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61738822"
     exon            1448..1501
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1477
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2236467"
     variation       1478
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375852929"
     variation       1484
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369917403"
     variation       1501
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373106775"
     exon            1502..1660
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1509
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371292624"
     variation       1532
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375739796"
     variation       1556
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368194132"
     variation       1558
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112723616"
     variation       1559
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375045387"
     variation       1584
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367836626"
     variation       1589
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:79292579"
     variation       1591
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200106008"
     variation       1596..1597
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35603970"
     variation       1598
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368600244"
     variation       1604
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:61737706"
     variation       1606
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372703675"
     variation       1622
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375198952"
     variation       1630
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369409660"
     exon            1661..1723
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1664
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375417533"
     variation       1672
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376461054"
     variation       1683
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373536407"
     variation       1691
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370509732"
     variation       1723
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181807938"
     exon            1724..1750
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1732
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75222922"
     variation       1736
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201476017"
     exon            1751..1882
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1809
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199823547"
     variation       1873
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370138639"
     exon            1883..1945
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1888
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369792535"
     variation       1900
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376114537"
     variation       1901
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368967629"
     variation       1914
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371586411"
     variation       1920
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377286160"
     variation       1930
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370015560"
     variation       1931
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181012655"
     exon            1946..1972
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1954
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199523495"
     variation       1969
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11702425"
     exon            1973..2008
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       1984
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367928373"
     variation       1985
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371970491"
     variation       1998
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376627920"
     variation       1999
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61731167"
     variation       2005
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372310838"
     exon            2009..2080
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2030
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:62000962"
     variation       2032
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375695180"
     variation       2044
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185089648"
     variation       2047
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:62000963"
     variation       2052..2053
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35277478"
     exon            2081..2116
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2083
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375058430"
     variation       2106
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367841049"
     exon            2117..2206
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2134
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373006940"
     variation       2140
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376084472"
     variation       2148
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370141116"
     variation       2149
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373318899"
     variation       2152
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377652187"
     variation       2166
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:79980197"
     variation       2168
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375408962"
     variation       2170
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377533410"
     variation       2176
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370417664"
     variation       2185
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374390595"
     variation       2187
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367570320"
     variation       2192
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372801767"
     variation       2197
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374522196"
     exon            2207..2236
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2215
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201512380"
     variation       2222
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116111018"
     variation       2229
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377720407"
     variation       2232
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:58380358"
     exon            2237..2263
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2241
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201805043"
     variation       2245
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115470104"
     variation       2252
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372137898"
     variation       2263
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199910738"
     exon            2264..2326
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2278
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376292745"
     variation       2303
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370009347"
     variation       2316
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370673713"
     exon            2327..2401
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2342
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371808014"
     variation       2353
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373455911"
     variation       2389
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2230693"
     exon            2402..2428
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2409
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367994730"
     variation       2410
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371966493"
     variation       2426
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376597265"
     variation       2427
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367551698"
     exon            2429..2482
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2437
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139122081"
     variation       2441
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201566264"
     variation       2445
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376924299"
     variation       2482
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200147240"
     exon            2483..2557
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2491
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375606333"
     variation       2500
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368730788"
     variation       2501
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372658384"
     variation       2526
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375575507"
     variation       2527
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369390092"
     variation       2539
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377601838"
     exon            2558..2626
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2559
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377444691"
     variation       2567
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372552105"
     variation       2617
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376919554"
     exon            2627..2669
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2627
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200779516"
     variation       2645
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372312684"
     variation       2650
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374530279"
     exon            2670..2732
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2672
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371993501"
     variation       2681
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377290522"
     variation       2693
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374976416"
     variation       2698
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369139821"
     variation       2712
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373528509"
     variation       2722
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191481067"
     exon            2733..2776
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2742
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201753320"
     variation       2743
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190374248"
     variation       2751..2753
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ttc"
                     /db_xref="dbSNP:371849586"
     variation       2754
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ttc"
                     /db_xref="dbSNP:78636159"
     exon            2777..2908
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2816
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372982447"
     variation       2830
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11544970"
     variation       2831
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187721798"
     variation       2836
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11544971"
     variation       2848
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370771189"
     variation       2864..2881
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ggcccccccggcccccca"
                     /db_xref="dbSNP:201180574"
     variation       2871
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="cggcccccc"
                     /db_xref="dbSNP:72301048"
     variation       2873..2881
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ggcccccca"
                     /db_xref="dbSNP:149296338"
     variation       2881
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:28696990"
     variation       2885
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="cccccaggc"
                     /db_xref="dbSNP:11276732"
     variation       2886
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="cccaggccc"
                     /db_xref="dbSNP:56328291"
     variation       2887..2888
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="cccaggccc"
                     /db_xref="dbSNP:78227997"
     variation       2889
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202106628"
     exon            2909..3053
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       2930
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371106773"
     variation       2936
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374058652"
     variation       2968
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368077149"
     variation       2969
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371933414"
     variation       2974
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375548890"
     variation       2975
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376598650"
     variation       2977
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367549674"
     variation       2987
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372973695"
     variation       2988
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200299380"
     variation       3001
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369702868"
     variation       3022
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367651350"
     variation       3042
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375478181"
     exon            3054..3127
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3062
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201381498"
     variation       3076
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370656151"
     variation       3115
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375254978"
     variation       3116
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367825934"
     exon            3128..3256
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3147
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199718927"
     variation       3164..3169
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="caggtg"
                     /db_xref="dbSNP:201754608"
     variation       3173
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200427354"
     variation       3182
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201265799"
     variation       3199
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371774034"
     variation       3223
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376728632"
     variation       3235
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374911370"
     variation       3236
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:369018715"
     variation       3238
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377152291"
     exon            3257..3289
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3270
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200839439"
     variation       3271
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12483761"
     variation       3282
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199583095"
     exon            3290..3535
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3314
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:76086392"
     variation       3351
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:187670025"
     variation       3354
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374207420"
     variation       3356
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377620137"
     variation       3381
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:112359725"
     variation       3392
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113268527"
     variation       3398
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372741290"
     variation       3419
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375753362"
     variation       3420
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370102608"
     variation       3427
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377093259"
     variation       3446
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199836125"
     variation       3459
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372765303"
     variation       3469
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375601931"
     variation       3484
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150227889"
     variation       3487
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1050351"
     variation       3520
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370921955"
     exon            3536..3733
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3550
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374326288"
     variation       3568
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:9980939"
     variation       3571
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376208451"
     variation       3572
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369592585"
     variation       3577
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373470254"
     variation       3579
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200484625"
     variation       3589
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370643343"
     variation       3619
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372559352"
     variation       3636
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375590764"
     variation       3647
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371038039"
     variation       3649
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114276639"
     variation       3650
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144147445"
     variation       3664
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370750158"
     variation       3665
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374880663"
     variation       3670
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368134801"
     variation       3686
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369304666"
     variation       3689
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371989063"
     variation       3696
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200043539"
     variation       3700
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367565307"
     variation       3705
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201006742"
     variation       3708
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377226690"
     variation       3712
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369895316"
     variation       3713
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77326997"
     variation       3721
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2838952"
     exon            3734..3849
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3742
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372684121"
     variation       3759
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375813847"
     variation       3775
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368913533"
     variation       3783
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373537140"
     variation       3790
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199498978"
     variation       3796
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371424181"
     variation       3797
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374321733"
     variation       3803
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199908300"
     variation       3818
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12483377"
     variation       3821
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375269967"
     variation       3830
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202104330"
     exon            3850..5382
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /inference="alignment:Splign:1.39.8"
     variation       3863
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:61736805"
     variation       3875
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200871316"
     variation       3877
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113315760"
     variation       3891
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202049650"
     variation       3901
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372279165"
     variation       3902
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370953127"
     variation       3940
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375390952"
     variation       3944
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370518474"
     variation       3945
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373708039"
     variation       3960
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61735035"
     variation       3968
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374822514"
     variation       3980
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372436243"
     variation       3996
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375488894"
     variation       4005
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201489582"
     variation       4011
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371861582"
     variation       4012
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375109205"
     variation       4066
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138930698"
     variation       4075
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:149459132"
     variation       4076
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7499"
     variation       4084
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369152864"
     variation       4089
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371710532"
     variation       4090
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373537387"
     variation       4093
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376696662"
     variation       4102
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369684141"
     variation       4131
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:8199"
     variation       4187
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369628824"
     STS             4249..4480
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /standard_name="SHGC-8080"
                     /db_xref="UniSTS:7730"
     variation       4273
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143852653"
     variation       4337
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17004784"
     variation       4351
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148610040"
     variation       4359
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183949177"
     variation       4362
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:17255281"
     variation       4366
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:17004785"
     variation       4400
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7867"
     variation       4408
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146206934"
     variation       4491
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368394587"
     variation       4499
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371166816"
     variation       4502
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11544972"
     variation       4834
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370216895"
     variation       4909
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:17255379"
     variation       4912
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:17004786"
     variation       4924
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:186538749"
     variation       4965
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367569832"
     variation       4978
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:117981301"
     STS             5020..5361
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /standard_name="SHGC-12530"
                     /db_xref="UniSTS:98863"
     variation       5103
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377445664"
     variation       5106
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1063505"
     STS             5138..5364
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /standard_name="SHGC-87711"
                     /db_xref="UniSTS:81506"
     variation       5207..5208
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ca"
                     /db_xref="dbSNP:143456926"
     variation       5208..5209
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ca"
                     /db_xref="dbSNP:78063943"
     variation       5208
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201512613"
     variation       5209..5210
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace=""
                     /replace="ca"
                     /db_xref="dbSNP:71868999"
     variation       5209
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1063507"
     variation       5251
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190947105"
     variation       5278
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144079697"
     variation       5297
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115900328"
     variation       5307
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182474443"
     variation       5321
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:78156175"
     polyA_signal    5359..5364
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
     polyA_site      5382
                     /gene="COL18A1"
                     /gene_synonym="KNO; KNO1; KS"
ORIGIN      
cgcggcggaggaggcagcatcccgcggcgctgacggtcctggggagagcatggcgccgaggtgcccctggccatggccgcggcggcggcgcctcctggacgtgctcgcgcccctggtcctgctgctcggggtccgcgcggcctccgcggagccagagcgcatcagcgaggaggtggggctgctgcagctccttggggaccccccgccccagcaggtcacccagacggatgaccccgacgtcgggctggcctacgtctttgggccagatgccaacagtggccaagtggcccggtaccacttccccagcctcttcttccgtgacttctcactgctgttccacatccggccagccacagagggcccaggggtgctgttcgccatcacggactcggcgcaggccatggtcttgctgggcgtgaagctctctggggtgcaggacgggcaccaggacatctccctgctctacacagaaccaggtgcaggccagacccacacagccgccagcttccggctccccgccttcgtcggccagtggacacacttagccctcagtgtggcaggtggctttgtggccctctacgtggactgtgaggagttccagagaatgccgcttgctcggtcctcacggggcctggagctggagcctggcgccgggctcttcgtggctcaggcggggggagcggaccctgacaagttccagggggtgatcgctgagctgaaggtgcgcagggacccccaggtgagccccatgcactgcctggacgaggaaggcgatgactcagatggggcatccggagactctggcagcgggctcggggacgcccgggagcttctcagggaggagacgggcgcggccctaaaacccaggctccccgcgccaccccccgtcaccacgccacccttggctggaggcagcagcacggaagattccagaagtgaagaagtcgaggagcagaccacggtggcttcgttaggagctcagacacttcctggctcagattctgtctccacgtgggacgggagtgtccggacccctgggggccgcgtgaaagagggcggcctgaaggggcagaaaggggagccaggtgttccgggcccacctggccgggcaggccccccaggatccccatgcctacctggtcccccgggtctcccgtgcccagtgagtcccctgggtcctgcaggcccagcgttgcaaactgtccccggaccacaaggacccccagggcctccggggagggacggcacccctggaagggacggcgagccgggcgaccccggtgaagacggaaagccgggcgacaccgggccacaaggcttccccgggactccaggggacgtaggtcccaagggcgacaagggagaccctggggttggagagagagggcccccaggaccccaagggcctccagggcccccaggaccctccttcagacacgacaagctgaccttcattgacatggagggatctggcttcgggggcgatctggaggccctgcggggtcctcgaggcttccctggacctcccggaccccccggtgtcccaggcctgcccggcgagccaggccgctttggggtgaacagctccgacgtcccaggacccgccggccttcctggtgtgcctgggcgcgagggtccccccgggtttcctggcctcccgggacccccaggccctccgggaagagaggggcccccaggaaggactgggcagaaaggcagcctgggtgaagcaggcgccccaggacataaggggagcaagggagcccccggtcctgctggtgctcgtggggagagcggcctggcaggagcccccggacctgctggaccaccaggcccccctgggccccctgggcccccaggaccaggactccccgctggatttgatgacatggaaggctccggggggcccttctggtcaacagcccgaagcgctgatgggccacagggacctcccggcctgccgggacttaagggggatcctggcgtgcctgggctgccgggggcgaagggagaagttggagcagatggagtccccgggttccccggcctccctggcagagagggcattgctgggccccaggggccaaagggagacagaggcagccggggagaaaagggagatccagggaaggacggagtcgggcagccgggcctccctggcccccccggacccccgggacctgtggtctacgtgtcggagcaggacggatccgtcctgagcgtgccgggacctgagggccggccgggtttcgcaggctttcccggacctgcaggacccaagggcaacctgggctctaagggcgaacgaggctccccgggacccaagggtgagaagggtgaaccgggcagcatcttcagccccgacggcggtgccctgggccctgcccagaaaggagccaagggagagccgggcttccgaggacccccgggtccatacggacggccggggtacaagggagagattggctttcctggacggccgggtcgccccgggatgaacggattgaaaggagagaaaggggagccgggagatgccagccttggatttggcatgaggggaatgcccggccccccaggacctccagggcccccaggccctccagggactcctgtttacgacagcaatgtgtttgctgagtccagccgccccgggcctccaggattgccagggaatcagggccctccaggacccaagggcgccaaaggagaagtgggcccccccggaccaccagggcagtttccgtttgactttcttcagttggaggctgaaatgaagggggagaagggagaccgaggtgatgcaggacagaaaggcgaaaggggggagcccgggggcggcggtttcttcggctccagcctgcccggcccccccggccccccaggcccacgtggctaccctgggattccaggtcccaagggagagagcatccggggccagcccggcccacctggacctcagggaccccccggcatcggctacgaggggcgccagggccctcccggccccccaggccccccagggcccccttcatttcctggccctcacaggcagactatcagcgttcccggccctccgggcccccctgggccccctgggccccctggaaccatgggcgcctcctcaggggtgaggctctgggctacacgccaggccatgctgggccaggtgcacgaggttcccgagggctggctcatcttcgtggccgagcaggaggagctctacgtccgcgtgcagaacgggttccggaaggtccagctggaggcccggacaccactcccacgagggacggacaatgaagtggccgccttgcagccccccgtggtgcagctgcacgacagcaacccctacccgcggcgggagcacccccaccccaccgcgcggccctggcgggcagatgacatcctggccagcccccctcgcctgcccgagccccagccctaccccggagccccgcaccacagctcctacgtgcacctgcggccggcgcgacccacaagcccacccgcccacagccaccgcgacttccagccggtgctccacctggttgcgctcaacagccccctgtcaggcggcatgcggggcatccgcggggccgacttccagtgcttccagcaggcgcgggccgtggggctggcgggcaccttccgcgccttcctgtcctcgcgcctgcaggacctgtacagcatcgtgcgccgtgccgaccgcgcagccgtgcccatcgtcaacctcaaggacgagctgctgtttcccagctgggaggctctgttctcaggctctgagggtccgctgaagcccggggcacgcatcttctcctttgacggcaaggacgtcctgaggcaccccacctggccccagaagagcgtgtggcatggctcggaccccaacgggcgcaggctgaccgagagctactgtgagacgtggcggacggaggctccctcggccacgggccaggcctcctcgctgctggggggcaggctcctggggcagagtgccgcgagctgccatcacgcctacatcgtgctctgcattgagaacagcttcatgactgcctccaagtagccaccgcctggatgcggatggccggagaggaccggcggctcggaggaagcccccaccgtgggcagggagcggccggccagcccctggccccaggacctggctgccatactttcctgtatagttcacgtttcatgtaatcctcaagaaataaaaggaagccaaagagtgtatttttttaaaagtttaaaacagaagcctgatgctgacattcacctgccccaactctcccctgacctgtgagcccagctgggtcaggcagggtgcagtatcatgccctgtgcaacctcttggcctgatcagaccacggctcgatttctccaggatttcctgctttgggaagccgtgctcgccccagcaggtgctgacttcatctcccacctagcagcaccgttctgtgcacaaaacccagacctgttagcagacaggccccgtgaggcaatgggagctgaggccacactcagcacaaggccatctgggctcctccagggtgtgtgctcgccctgcggtagatgggagggaggctcaggtccctggggctagggggagccccttctgctcagctctgggccattctccacagcaaccccaggctgaagcaggttcccaagctcagaggcgcactgtgacccccagctccggcctgtcctccaacaccaagcacagcagcctggggctggcctcccaaatgagccatgagatgatacatccaaagcagacagctccaccctggccgagtccaagctgggagattcaagggacccatgagttggggtctggcagcctcccatccagggcccccatctcatgcccctggctgggacgtggctcagccagcacttgtccagctgagcgccaggatggaacacggccacatcaaagaggctgaggctggcacaggacatgcggtagccagcacacagggcagtgagggagggctgtcatctgtgcactgcccatggacaggctggctccagatgcagggcagtcattggctgtctcctaggaaacccatatccttaccctccttgggactgaaggggaaccccggggtgcccacaggccgccctgcgggtgaacaaagcagccacgaggtgcaacaaggtcctctgtcagtcacagccacccctgagatccggcaacatcaacccgagtcattcgttctgtggagggacaagtggactcagggcagcgccaggctgaccacagcacagccaacacgcacctgcctcaggactgcgacgaaaccggtggggctggttctgtaattgtgtgtgatgtgaagccaattcagacaggcaaataaaagtgaccttttacactgaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:80781 -> Molecular function: GO:0005198 [structural molecule activity] evidence: IEA
            GeneID:80781 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:80781 -> Molecular function: GO:0042802 [identical protein binding] evidence: IPI
            GeneID:80781 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
            GeneID:80781 -> Biological process: GO:0001525 [angiogenesis] evidence: IEA
            GeneID:80781 -> Biological process: GO:0001886 [endothelial cell morphogenesis] evidence: IEA
            GeneID:80781 -> Biological process: GO:0007155 [cell adhesion] evidence: IEA
            GeneID:80781 -> Biological process: GO:0007601 [visual perception] evidence: TAS
            GeneID:80781 -> Biological process: GO:0008284 [positive regulation of cell proliferation] evidence: IEA
            GeneID:80781 -> Biological process: GO:0008285 [negative regulation of cell proliferation] evidence: TAS
            GeneID:80781 -> Biological process: GO:0009887 [organ morphogenesis] evidence: TAS
            GeneID:80781 -> Biological process: GO:0022617 [extracellular matrix disassembly] evidence: TAS
            GeneID:80781 -> Biological process: GO:0030198 [extracellular matrix organization] evidence: TAS
            GeneID:80781 -> Biological process: GO:0030335 [positive regulation of cell migration] evidence: IEA
            GeneID:80781 -> Biological process: GO:0030574 [collagen catabolic process] evidence: TAS
            GeneID:80781 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IEA
            GeneID:80781 -> Cellular component: GO:0005576 [extracellular region] evidence: TAS
            GeneID:80781 -> Cellular component: GO:0005581 [collagen] evidence: IEA
            GeneID:80781 -> Cellular component: GO:0005604 [basement membrane] evidence: IEA
            GeneID:80781 -> Cellular component: GO:0005615 [extracellular space] evidence: IDA
            GeneID:80781 -> Cellular component: GO:0005788 [endoplasmic reticulum lumen] evidence: TAS
            GeneID:80781 -> Cellular component: GO:0031012 [extracellular matrix] evidence: IDA
            GeneID:80781 -> Cellular component: GO:0031012 [extracellular matrix] evidence: TAS

by @meso_cacase at DBCLS
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