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2024-04-24 01:10:01, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_080797 7657 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens death inducer-obliterator 1 (DIDO1), transcript
variant 3, mRNA.
ACCESSION NM_080797
VERSION NM_080797.3 GI:301129166
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7657)
AUTHORS Braig,S. and Bosserhoff,A.K.
TITLE Death inducer-obliterator 1 (Dido1) is a BMP target gene and
promotes BMP-induced melanoma progression
JOURNAL Oncogene 32 (7), 837-848 (2013)
PUBMED 22469980
REMARK GeneRIF: Dido1 induces the expression of Integrin alphaV, thereby
promoting the attachment, migration, invasion and apoptosis
resistance of melanoma cells.
REFERENCE 2 (bases 1 to 7657)
AUTHORS Sillars-Hardebol,A.H., Carvalho,B., Belien,J.A., de Wit,M.,
Delis-van Diemen,P.M., Tijssen,M., van de Wiel,M.A., Ponten,F.,
Meijer,G.A. and Fijneman,R.J.
TITLE CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma
progression
JOURNAL Cell Oncol (Dordr) 35 (4), 293-300 (2012)
PUBMED 22711543
REMARK GeneRIF: Data show that CSE1L, DIDO1 and RBM39 mRNA expression
levels correlated with chromosome 20q DNA copy number status.
REFERENCE 3 (bases 1 to 7657)
AUTHORS Flachsbart,F., Franke,A., Kleindorp,R., Caliebe,A., Blanche,H.,
Schreiber,S. and Nebel,A.
TITLE Investigation of genetic susceptibility factors for human longevity
- a targeted nonsynonymous SNP study
JOURNAL Mutat. Res. 694 (1-2), 13-19 (2010)
PUBMED 20800603
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 4 (bases 1 to 7657)
AUTHORS Liu,C.Y., Wu,M.C., Chen,F., Ter-Minassian,M., Asomaning,K.,
Zhai,R., Wang,Z., Su,L., Heist,R.S., Kulke,M.H., Lin,X., Liu,G. and
Christiani,D.C.
TITLE A Large-scale genetic association study of esophageal
adenocarcinoma risk
JOURNAL Carcinogenesis 31 (7), 1259-1263 (2010)
PUBMED 20453000
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 5 (bases 1 to 7657)
AUTHORS Yoshida,T., Kato,K., Yokoi,K., Oguri,M., Watanabe,S., Metoki,N.,
Yoshida,H., Satoh,K., Aoyagi,Y., Nozawa,Y. and Yamada,Y.
TITLE Association of genetic variants with hemorrhagic stroke in Japanese
individuals
JOURNAL Int. J. Mol. Med. 25 (4), 649-656 (2010)
PUBMED 20198315
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 7657)
AUTHORS Fu,G.K., Wang,J.T., Yang,J., Au-Young,J. and Stuve,L.L.
TITLE Circular rapid amplification of cDNA ends for high-throughput
extension cloning of partial genes
JOURNAL Genomics 84 (1), 205-210 (2004)
PUBMED 15203218
REFERENCE 7 (bases 1 to 7657)
AUTHORS Mochi,M., Cevoli,S., Cortelli,P., Pierangeli,G., Soriani,S.,
Scapoli,C. and Montagna,P.
TITLE A genetic association study of migraine with dopamine receptor 4,
dopamine transporter and dopamine-beta-hydroxylase genes
JOURNAL Neurol. Sci. 23 (6), 301-305 (2003)
PUBMED 12624717
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 8 (bases 1 to 7657)
AUTHORS Gomes,I., Sharma,T.T., Edassery,S., Fulton,N., Mar,B.G. and
Westbrook,C.A.
TITLE Novel transcription factors in human CD34 antigen-positive
hematopoietic cells
JOURNAL Blood 100 (1), 107-119 (2002)
PUBMED 12070015
REMARK GeneRIF: Novel transcription factors identified in human CD34
antigen-positive hematopoietic stem cells.
REFERENCE 9 (bases 1 to 7657)
AUTHORS Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
Rogers,J.
TITLE The DNA sequence and comparative analysis of human chromosome 20
JOURNAL Nature 414 (6866), 865-871 (2001)
PUBMED 11780052
REFERENCE 10 (bases 1 to 7657)
AUTHORS Garcia-Domingo,D., Leonardo,E., Grandien,A., Martinez,P.,
Albar,J.P., Izpisua-Belmonte,J.C. and Martinez-A,C.
TITLE DIO-1 is a gene involved in onset of apoptosis in vitro, whose
misexpression disrupts limb development
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 96 (14), 7992-7997 (1999)
PUBMED 10393935
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA294135.1, AB002331.2,
AL035669.43 and AW206895.1.
On Jul 23, 2010 this sequence version replaced gi:71044476.
Summary: Apoptosis, a major form of cell death, is an efficient
mechanism for eliminating unwanted cells and is of central
importance for development and homeostasis in metazoan animals. In
mice, the death inducer-obliterator-1 gene is upregulated by
apoptotic signals and encodes a cytoplasmic protein that
translocates to the nucleus upon apoptotic signal activation. When
overexpressed, the mouse protein induced apoptosis in cell lines
growing in vitro. This gene is similar to the mouse gene and
therefore is thought to be involved in apoptosis. Alternatively
spliced transcripts have been found for this gene, encoding
multiple isoforms. [provided by RefSeq, Jul 2008].
Transcript Variant: This variant (3) contains a different terminal
exon, compared to variant 4. It encodes a protein (isoform b) that
has a distinct and shorter C-terminus when it is compared to
isoform c. Variants 3 and 6 encode the same protein (isoform c).
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AB002331.2 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-68 DA294135.1 1-68
69-5983 AB002331.2 1-5915
5984-6542 AL035669.43 137492-138050 c
6543-7626 AB002331.2 5916-6999
7627-7657 AW206895.1 1-31 c
FEATURES Location/Qualifiers
source 1..7657
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="20"
/map="20q13.33"
gene 1..7657
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/note="death inducer-obliterator 1"
/db_xref="GeneID:11083"
/db_xref="HGNC:2680"
/db_xref="HPRD:10363"
/db_xref="MIM:604140"
exon 1..157
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
exon 158..354
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
variation 165
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="c"
/replace="t"
/db_xref="dbSNP:11544691"
misc_feature 252..254
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/note="upstream in-frame stop codon"
exon 355..1195
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
CDS 357..3926
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/note="isoform b is encoded by transcript variant 3;
death-associated transcription factor 1"
/codon_start=1
/product="death-inducer obliterator 1 isoform b"
/protein_id="NP_542987.2"
/db_xref="GI:71044477"
/db_xref="CCDS:CCDS13508.2"
/db_xref="GeneID:11083"
/db_xref="HGNC:2680"
/db_xref="HPRD:10363"
/db_xref="MIM:604140"
/translation="
MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLSLRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASETRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERPLKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEGKAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
"
misc_feature 357..359
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="N-acetylmethionine; propagated from
UniProtKB/Swiss-Prot (Q9BTC0.5); acetylation site"
misc_feature 807..809
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q9BTC0.5); phosphorylation site"
misc_feature 807..809
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 810..812
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9BTC0.5); phosphorylation site"
misc_feature 810..812
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 816..818
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9BTC0.5); phosphorylation site"
misc_feature 816..818
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 822..824
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature <834..1262
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/note="Chromatin remodeling protein, contains PhD zinc
finger [Chromatin structure and dynamics]; Region: TNG2;
COG5034"
/db_xref="CDD:34639"
misc_feature 849..875
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BTC0.5);
Region: Nuclear localization signal (Potential)"
misc_feature 909..935
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BTC0.5);
Region: Nuclear localization signal (Potential)"
misc_feature 1164..1316
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/note="PHD-finger; Region: PHD; pfam00628"
/db_xref="CDD:201356"
misc_feature 2370..2675
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/note="Domain in the central regions of transcription
elongation factor S-II (and elsewhere); Region: TFS2M;
smart00510"
/db_xref="CDD:128786"
misc_feature 2385..2387
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2769..2771
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9BTC0.5); phosphorylation site"
misc_feature 2781..2783
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9BTC0.5); phosphorylation site"
misc_feature 2781..2783
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2787..2789
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2805..2807
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3048..3050
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9BTC0.5); phosphorylation site"
misc_feature 3048..3050
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3411..3413
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9BTC0.5); phosphorylation site"
misc_feature 3444..3446
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9BTC0.5); phosphorylation site"
misc_feature 3474..3476
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9BTC0.5); phosphorylation site"
misc_feature 3474..3476
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3525..3845
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/note="SPOC domain; Region: SPOC; pfam07744"
/db_xref="CDD:203754"
variation 588
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="c"
/replace="t"
/db_xref="dbSNP:35714670"
variation 764
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="a"
/replace="g"
/db_xref="dbSNP:36034272"
variation 1082
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="a"
/replace="g"
/db_xref="dbSNP:34097003"
variation 1157
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="c"
/replace="t"
/db_xref="dbSNP:34047884"
exon 1196..1517
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
exon 1518..1730
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
variation 1628
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="a"
/replace="g"
/db_xref="dbSNP:34820000"
exon 1731..1944
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
exon 1945..2410
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
variation 1996
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="a"
/replace="c"
/db_xref="dbSNP:80279994"
exon 2411..2570
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
exon 2571..2687
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
exon 2688..2792
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
variation 2734
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="c"
/replace="g"
/db_xref="dbSNP:750077"
variation 2774
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="a"
/replace="g"
/db_xref="dbSNP:750078"
exon 2793..2928
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
exon 2929..3457
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
exon 3458..3611
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
exon 3612..3701
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
exon 3702..7643
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/inference="alignment:Splign:1.39.8"
variation 5415
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="a"
/replace="g"
/db_xref="dbSNP:3746765"
variation 5484..5485
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace=""
/replace="a"
/db_xref="dbSNP:3833336"
STS 5705..6029
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/standard_name="SHGC-57951"
/db_xref="UniSTS:75228"
variation 5739
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="c"
/replace="t"
/db_xref="dbSNP:201803216"
variation 6221
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="c"
/replace="t"
/db_xref="dbSNP:3746766"
variation 6343
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="a"
/replace="g"
/db_xref="dbSNP:3746767"
variation 6372
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="a"
/replace="c"
/db_xref="dbSNP:3746768"
variation 6591
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="a"
/replace="g"
/db_xref="dbSNP:3746769"
variation 7167
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/replace="a"
/replace="g"
/db_xref="dbSNP:1056984"
STS 7385..7586
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/standard_name="RH25609"
/db_xref="UniSTS:87957"
STS 7411..7567
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/standard_name="SHGC-2352"
/db_xref="UniSTS:23735"
STS 7421..7630
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
/standard_name="SHGC-24151"
/db_xref="UniSTS:75978"
polyA_signal 7623..7628
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
polyA_site 7643
/gene="DIDO1"
/gene_synonym="BYE1; C20orf158; DATF-1; DATF1; DIDO2;
DIDO3; DIO-1; DIO1; dJ885L7.8"
ORIGIN
gtacttgcgcagaactcccctcgcggcgaccacgcactacgggttggcgccagagtcaaaaggcgtcggccctctggcaagatggctgctgcggaggcgttggagcgcggaaatctggaaccgggatggcgacgtctacactgagtcggaggcgaaggagcttactccacgggaacagcctctagataatctgagttgttgaaaatacgaagcctgttactcgtgaacagtggctgacaacagtgttgttgtgagcctggctgtctgcttggacccagaggtttcgtctgccagggtttttggttgtatttaggatttcagggaaaagtgtccaagctttcagtgttggagcaggtatggacgacaaaggcgacccgagcaatgaggaggcacctaaggccatcaaacccaccagcaaagagttcaggaaaacatggggttttcgaaggaccactatcgccaagcgagagggcgcaggggacgcggaggctgacccactggagccgccacccccacagcagcagctgggcctgtccctgcggcgcagtgggaggcagcccaagcgcactgagcgcgtggagcagttcctgaccattgcgcggcgccgcggcaggaggagcatgcctgtctccctggaggattctggtgagcccacgtcctgccccgccacagacgccgagacagcctccgagggcagcgtggaaagcgcttctgagaccagaagcggcccccagtctgcttccacagctgtgaaggaacgaccagcctcttctgaaaaggtgaaaggaggggatgaccacgatgacacctccgatagtgacagcgatggcctgaccttgaaagagcttcagaatcgccttcgcaggaagcgggaacaggagcccactgagaggcccctgaaagggatccagagtcgcctgcggaagaagcgccgggaggagggtcccgccgagactgtgggctccgaggccagtgacactgtggagggcgtcctgcccagtaagcaggagcccgagaacgatcagggggttgtgtcccaggctgggaaagatgacagagagagtaagttggagggaaaggcggctcaggacatcaaagatgaggagcctggagacttgggccgaccgaagcctgaatgtgagggttacgaccccaacgccctgtattgcatttgccgccagcctcacaacaacaggtttatgatttgctgtgaccgctgtgaagaatggtttcatggcgattgtgtgggcatttctgaggctcgagggaggcttttggaaaggaatggggaagactatatctgcccaaactgcaccattctgcaagtgcaggatgagactcattcagaaacggcagatcagcaggaagctaaatggagacctggagatgctgatggcaccgattgtacaagtataggaacaatagagcagaagtctagcgaagaccaagggataaagggtagaattgagaaagctgcaaatccaagtggcaagaagaaactcaagatcttccagcctgtgatagaggcgcctggtgcctcaaaatgtattggccccgggtgctgtcacgtggcgcagcccgactcggtgtactgcagtaatgactgtatcctcaaacacgccgcagcgacaatgaagtttctaagctcaggtaaagaacagaagccaaagcctaaagaaaagatgaagatgaagccagagaagcccagtcttccgaaatgcggtgctcaggcaggtattaaaatctcttctgtgcacaagagaccagctccagaaaaaaaagagaccacagtgaagaaggcagtggtggtccctgcgcggagtgaagcactcgggaaggaagcagcttgtgagagcagcacgccgtcgtgggcgagcgatcacaattacaatgcagtaaagccagaaaagactgctgctccctcgccgtcactgttgtataaatccacgaaggaagacaggaggtccgaggagaaagcggcagccatggcagcctcaaagaaaacagcccctccaggctccgcggtgggcaagcagcctgcacctagaaacctcgtgccaaagaagtcttcttttgctaatgtggcagcagccacaccagccattaaaaagccaccctcaggtttcaagggcaccatccccaagaggccatggctctccgctaccccatcgagtggtgcttcagctgccaggcaggccggaccggcacctgcagcggcaacggctgcctccaagaagttccctggctccgctgctttggtgggagccgtaaggaagccagtggtaccttctgttccaatggcctcgccagccccaggacgccttggggctatgagtgctgcaccatcgcagccaaattcacaaattcggcaaaatatcagacgctccttaaaagagattttgtggaaaagagtcaatgacagcgatgacttaatcatgacagaaaacgaagtaggaaaaattgccctccatattgagaaggagatgtttaacttgtttcaagttacagataatcgctacaagagtaaatatcgcagcatcatgttcaacctgaaggaccctaaaaatcagggactcttccatcgtgttctgcgtgaggaaatctctttggcgaaacttgtgagactgaagccagaagaacttgtatctaaagagctttccacgtggaaagagaggccagcgagatctgtgatggagtccagaactaaactgcacaatgaaagcaagaagacggcccccaggcaggaggccatccccgatctggaggactctccgccagtgtcggattcagaggaacagcaagagtcagcacgtgctgtccctgagaagagcacagcgccgcttctcgacgtcttcagcagcatgttgaaagacaccaccagtcagcaccgcgcacacctcttcgatctcaactgtaaaatttgcacaggccaggttccctccgcagaagatgagccagctccgaaaaaacaaaaattgtcagcttctgttaagaaagaagacttaaaatcaaagcatgacagctctgcacctgacccagctccggattcagctgatgaggtgatgccggaggctgtgcctgaagttgcctctgagccaggcctagaaagtgcttctcatccaaatgtggacagaacgtatttccctgggcctccaggagatggccatcccgagccctccccgctggaagacctgtccccctgcccagcctcctgtgggagcggggtggtcaccaccgtcacagtgtccggccgggaccccaggaccgctccaagcagttcatgcacagccgtggcctccgcagcatcccgcccagacagcacccacatggtggaagccagacaggatgtgccgaagcctgtcttgacttctgtgatggtgcccaagtccatactagctaagccatcctcatctcctgacccaagatacctgtcagttcctccgtcaccaaatatcagcacttcagaatcacgttcccctccagagggagacacgaccctctttttgtctcgactcagcaccatttggaaaggatttattaacatgcagagtgtggcaaaatttgtcactaaggcgtatcctgtctctgggtgttttgattacctcagtgaggatttgcctgacacaattcacattggtgggaggatcgcaccgaagacagtttgggattatgttggcaaactcaagtcttctgtgtctaaggagctctgtctgatccgcttccaccccgccacagaggaagaggaggtcgcctatatctctctctactcctatttcagcagccgtggccgctttggtgttgtagctaataacaacaggcacgtcaaggacctctacctgatcccgctgagcgcccaggaccctgttccatccaaactcttgccctttgagggaccaggtaagcgccggctttctgggtggaggtgaggcccacctgcacctgcacccctcctcccactgacatgccctgctgagtcctgaccagcccagggctctctgggagcaggagttaggagcacagacgcagcggttagcaataggattcatctttgagggcgtaggactgtggcacgagaagtacccctgattcacagcataaattgtcttaggagagttttttagagagggaaaaacccacagcctgcaaccagctcatcttggcctcaggtcagagaagactcagtgcccagaagcccaaggctcagccagaaagggaggtgacactcccagcggccctgctctttcctctagacagactcgggagccagcacacaccgggaagtggctccatcagggatcacttctctaacagggatggatttccaggagacttaacaataatgacatagaaaactatttctagaaataattattttaaaatctgcagctcaaattgtaataggttcattcatctttggcaagctattttgtgtttgcacgttccttggaaagtactgtatttaaacgattatttacaaatagcctaaaatacatctttgtcaagggttgagggtgattccaggggccacgtgctctgttagtgaccagctctttcatagccccttagaagaagctgatgtgacttcagttaggggttagtatctgatgcccaactgaagtgtctccgtggccatgcagtccccagaggattggtgttctctcaaagcgggtgtgtggatcacacagtgtcctctgaagtgcttcgtcataaaggcaggtgctgtctggaccctgtgcctcagtgccctctgtccctgtcaccaggcctcggcgggtgttcctgccatagctgtgcagggtgttcccacccacacccctcatgccgcaccctagctagctggggtcctgtaggggccactccacatcttgggcgggacttctgtcgccccaggcacagcccacgttcctactggagcccattcttcacagctggagtgggctcagcctatgcctgtgttgtggaattatatgtccataaagggattggttggtatcagtaatttcagggttaaatatttgctggcgtggtgcattaaattattttagtgccagataaatttttaaaagcaaagtgctttagtgtgtcccctcaaatcctacttgggataaagagatgccacctaatgggtggcagaaaggaccctggtagaggttcttggtgttgcttgtgaagagctctggccagctccacgtgaccagggagaggaaaagcccggccctcctggaggtgaagaccgagaagctggcctctccgcacctgtgaagacccactggtcagttgcaagtgcgacagtgtgtgcactcagtgcagacactgcagcacctcagcacctccctaccggggtggaaagagcactttttctttacagaaacatgattcttagatagcgagcctcccctttttaaaacaattgaggcgatatttcatcctttcttgagcttctctccctgctcatctccaaacttggagctgtcaggtgagcacggttgtagggtgttgagcgagccccggcgcatgccgggcaccgggttccccacactgggcagtgacggggcccagggaggccaccagaggagcggcgcctccattctccccacagcaagggctggctgtgcaggtgcagccccggggcagagggaaaggacaggtctcccagcacctcccggatggcaccgggacaaggagggctgggctggggtcactcaccttgtctgctgagtgcgatggcaccaaccacccacactgtcagctccgcgaccagctgggggaacgtcacactcgcccaccaaggcacttgctgaggccacgacgccgcctgacggggacacacaaaagccccagggactttgatccacgataaagagcagaggcgtctgggtaaagtaacacagggcaagggactttagaaaagtaacagctagtgaaacctttccatacacttcagaaatgttttaacttaagacttcagtataatgttaacttctcctgatgtccttgttgacatgaatgcgtgtgcgtgaaatctcacacacttccatggtcactaaacagccttcaccccgggccaggccatcgggtactcggcccgcttcacgtactgattacttgacttggcgttttctagatataaacatgtacatgtgtgtcctggctttgtggtgtaaatgtgtagtgcgtgtgcatgtgcgcgcgtgtgtgtgtgtaaggctaggtcctggcatgtttcccctgtctcagcggaccctgtcctcacggagatagcccagaagcccttggacagcacaggccacacctgagggtgctgatggtggtgactccacagagctgtggtcaggggtgagcgtgtgctgcgcagcttggagtcacgcccccagaagtgctgggtgagggtctgcaggacccagctccattccacagcctcagttctctgcggcacatgcagcacaggcctgaaggagacctggcgccccagccttgagctgcccgtctgcatcagggcactgatgtgggagcatcttcccctggggatgttaaggagaaggtcctgttgggggtagagattcacgcagaaaagagtgactgactcgtccatgtgcctcagtttataccacacaattgcaggtgtccatgcctcccacacatggggacctagtgggttttgacagcgtggtgtccagtcctagccccctcagtgcttgctgttcacacttaagcaagtgaaggcctgaaggtgcccagctgtgccctcaggggaaacttaagtcacccgccctgtcagcacttggcccttgtcgggcagtgagagtggagctgcccccgcagcaccctcaggagccatgcagttcacagcagtagctggatctccctgaggacatttgtccttgcatatcttaatgatttgtccacagaaacaccgggttgtcttcctctgcccctctgccccgcagtgggggcactctctgtaactcagcatcacggtggggggcagctgggaggcctggttccaggtgaccttctccacctagatgttcaccccactcagttccagctttaccaacagggccccccgcagggacttggggtcgcagagtcccggcctgtctcagggccttgttcatggaagggagatgagtcaggttgaaagctcatcgtgtagggttctgtgcagggcccttacaggactggaccgcagccaagatgcctgcctgttaaccatgcccagcccccgtcatttccgcgtgaagccgcaggcctcggagccttggtctgaaatgcctgtggagtaacctcggtccataaacatgggtgcacagtctgttctccccaagtacagggcaggaggaaacaccgccctctgtagctgctcgaatggaaagggctcttttctctgaggtctttatacattagaaagctcttctgggaagaatgtttgaatccatagtgtctttctgtattcacttttaattgctttctaaattagctgagaaattctgacttgaaatattgtcaggtaagcatttcttcagttttcatgtgtgtatgtaacagtagctttgcatggaaattgtaatcagagtcaaatacagtattgaatggaatgtactgccttctcctcctaaatcaataaacatctttcatggaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:11083 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
GeneID:11083 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:11083 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:11083 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
GeneID:11083 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA
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DBCLS
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